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Primary sex organs (gonads)
Testes in males and ovaries in females; produce gametes and secrete sex hormones.
Gametes
Sex cells; sperm in males and ova in females.
Androgens
Male steroid sex hormones, primarily testosterone.
Estrogens
Female steroid sex hormones including estradiol, estrone, and estriol.
Progesterone
Female steroid sex hormone important for maintaining the uterine lining and pregnancy.
Accessory reproductive organs
Reproductive structures other than the gonads; include ducts, glands, and external genitalia.
Scrotum
Sac of skin outside the abdominopelvic cavity that contains the testes.
Raphe
Midline septum that divides the scrotum into two compartments.
Dartos muscle
Smooth muscle that wrinkles scrotal skin and pulls the testes closer to the body.
Cremaster muscles
Skeletal muscles that elevate the testes.
Why are the testes outside the body cavity?
Sperm production requires a temperature about 3°C below core body temperature.
Tunica vaginalis
Outer serous covering surrounding each testis.
Tunica albuginea
Inner fibrous capsule surrounding the testis; sends septa into the testis.
Testicular lobules
Compartments of the testis formed by septa; each contains about 1–4 seminiferous tubules.
Seminiferous tubules
Tubules in the testes where sperm are produced.
Straight tubules
Short tubules that receive sperm from seminiferous tubules and carry them toward the rete testis.
Rete testis
Network of tubules that concentrates sperm and reabsorbs excess fluid.
Pampiniform venous plexus
Network of veins surrounding the testicular arteries that cools arterial blood before it enters the testes.
Spermatic cord
Structure containing the ductus deferens, blood vessels, nerves, and lymphatics supplying the testis.
Epididymis
Coiled duct where sperm mature, gain motility, and are stored.
Head of epididymis
Superior portion of epididymis that receives sperm from efferent ductules.
Tail of epididymis
Lower portion of epididymis where mature sperm are stored before ejaculation.
Ductus deferens (vas deferens)
Muscular duct about 45 cm long that transports sperm from the epididymis toward the ejaculatory duct.
Ampulla (male)
Expanded portion of the ductus deferens where sperm can be stored before ejaculation.
Vasectomy
Procedure in which the ductus deferens is cut and tied off to provide permanent birth control.
Ejaculatory duct
Duct formed by the union of the ductus deferens and seminal gland duct; empties into the prostatic urethra.
Urethra
Terminal duct that carries urine and semen out of the male body at different times.
Prostatic urethra
Part of the urethra surrounded by the prostate.
Intermediate urethra
Short portion of the urethra between the prostatic and spongy urethra.
Spongy urethra
Portion of the urethra that runs through the penis and opens at external urethral orifice.
Penis
Male copulatory organ that delivers sperm into the female reproductive tract.
Glans penis
Enlarged distal end of the penis.
Prepuce (foreskin)
Cuff of loose skin covering the glans penis.
Circumcision
Surgical removal of the foreskin.
Corpus cavernosa
Paired erectile bodies that make up most of the penis.
Corpus spongiosum
Erectile tissue surrounding the urethra that helps keep it open during erection.
Erection
Enlargement and stiffening of the penis caused by blood filling erectile tissue.
Seminal glands (seminal vesicles)
Accessory glands that produce viscous alkaline fluid making up about 70% of semen volume.
Seminal vesicle fluid
Contains fructose, prostaglandins, and coagulating enzymes.
Fructose
Provides energy for ATP production and supports sperm movement.
Prostaglandins
Helps sperm move through female reproductive tract.
Prostate
Doughnut-shaped gland below the bladder that surrounds the urethra.
Prostatic fluid
Milky, slightly acidic fluid containing citrate, enzymes, and PSA; makes up about one-third of semen.
PSA (prostate-specific antigen)
Enzyme in prostatic fluid that helps liquefy semen.
Bulbo-urethral glands
Pea-sized glands inferior to the prostate that secrete clear mucus that lubricates the urethra/glan.
Semen
Milky-white mixture of sperm and secretions from the accessory reproductive glands.
Normal semen volume
Approximately 2–5 mL per ejaculation.
Path of sperm
Seminiferous tubules → straight tubules → rete testis → efferent ductules → epididymis → ductus deferens → ejaculatory duct → urethra → exterior.
Spermatogenesis
The production of sperm in the seminiferous tubules.
When does spermatogenesis begin?
At approximately puberty, around age 14, and it continues throughout life.
Three steps of spermatogenesis
Mitosis of spermatogonia → meiosis → spermiogenesis.
Spermatids
Immature sperm.
HPG axis (male)
Hypothalamic-pituitary-gonadal axis; hormonal system regulating gamete and sex hormone production.
GnRH
Gonadotropin-releasing hormone released by the hypothalamus that stimulates the anterior pituitary.
FSH (male)
Stimulates sperm production and supports spermatogenesis.
LH (male)
Stimulates testosterone production by the testes.
Testosterone
Main male sex hormone; supports sperm production and male secondary sex characteristics.
Testosterone before birth
Male fetal testosterone levels reach about two-thirds of adult levels.
Testosterone during childhood
Levels decrease after birth and remain relatively low until puberty.
Testosterone secondary sex effects
Promotes facial, chest, and pubic hair; deepens the voice; increases bone density and muscle mass; increases metabolic rate and libido.
Female primary sex organs
Ovaries.
Female gametes
Ova (egg cells).
Female reproductive hormones
Estrogens and progesterone.
Internal female genitalia
Ovaries, uterine tubes, uterus, and vagina.
External female genitalia (vulva)
Labia majora, labia minora, clitoris, mons pubis, vestibule, and greater vestibular glands.
Ovary
Paired female gonad that produces oocytes and secretes estrogen and progesterone.
Ovarian cortex
Outer region of the ovary containing developing ovarian follicles.
Ovarian medulla
Inner region of the ovary containing large blood vessels and nerves.
Ovarian follicle
Saclike structure in the ovarian cortex containing an immature oocyte.
Primordial follicle
Follicle containing a primary oocyte surrounded by a single layer of follicular cells.
Primary follicle
Developing follicle in which follicular cells become cuboidal and proliferate.
Secondary follicle
Follicle with multiple layers of granulosa cells surrounding the oocyte.
Granulosa cells
Follicle cells that support the oocyte and respond to FSH.
Vesicular (antral) follicle
Mature follicle containing a large fluid-filled antrum.
Ovulation
Release of a secondary oocyte from a mature ovarian follicle.
LH surge
Rapid increase in LH that triggers ovulation and formation of the corpus luteum.
Mittelschmerz
Occasional pain or twinge experienced around ovulation.
Corpus luteum
Structure formed from the ruptured follicle after ovulation; secretes progesterone and some estrogen.
Corpus albicans
Scar tissue left behind after the corpus luteum degenerates.
Uterine tubes (fallopian tubes)
Tubes that receive the ovulated oocyte and are the usual site of fertilization.
Infundibulum
Funnel-shaped distal end of the uterine tube that catches the ovulated oocyte.
Fimbriae
Ciliated projections of the infundibulum that sweep the oocyte into the uterine tube.
Ampulla of uterine tube
Widest region of the uterine tube and usual site of fertilization.
Isthmus of uterine tube
Narrow region connecting the uterine tube to the uterus.
Uterus
Hollow, muscular organ that receives, retains, and nourishes a fertilized ovum.
Anteverted uterus
Uterus tilted forward toward the bladder.
Retroverted uterus
Uterus tilted backward toward the spine.
Fundus
Superior rounded portion of the uterus.
Isthmus of uterus
Narrow inferior region between the body and cervix.
Cervix
Narrow inferior neck of the uterus that projects into the vagina.
Internal os
Opening connecting the uterine body to the cervical canal.
External os
Opening connecting the cervical canal to the vagina.
Perimetrium
Outermost serous layer of the uterine wall.
Myometrium
Middle layer of the uterine wall made of smooth muscle; contracts during childbirth.
Endometrium
Inner uterine lining where a fertilized egg implants (2 layers).
Stratum functionalis
Functional layer of the endometrium that responds to hormones and is shed during menstruation.
Stratum basalis
Basal layer of the endometrium that remains after menstruation and regenerates the functional layer.
Vagina
8–10 cm muscular tube serving as the birth canal, passageway for menstrual flow, and organ of copulation.
Vulva
Collective term for the external female genitalia.
Mons pubis
Fatty area over the pubic symphysis that becomes covered with pubic hair.