Puritis II

Where do dermatophytosis commonly infect?

Hair and stratum corneum

Who is most susceptible to dermatophytes?

Young Yorkies and Persians

What are features of dermatophytosis?

Well-demarcated alopecia

Crusts/ scales

Furunculosis

What are gold standard tests for dermatophytosis?

Dermatophyte test medium

PCR testing

You can see macroconidia from ___ and microconidia on _____?

DTM

Cytology

Identify?

Microcondidia

Identify?

Macrocondidium

A DTM culture will never be what colors?

Grey

Black

Green

What is the desired theraphy for dermatophytes?

Malseb - chlorohex + miconazole

Lyme sulfer

If you must use oral tx for dermatophytes, what is recommended?

Itraconozole

Terbinafine

What antifungal should we not use in cats?

Ketoconazole

When can you D/C dermatophytosis Tx?

2 consecutive neg DTM cultures -> cured

What is seb adenitis?

auto immune dz destroying seb glands

Who gets Seb adenitis most commonly?

Poodles

Akitas

What is the most common clinical sign of seb adenitis?

Follicular casts

-loss of curls/ coat color change

(neck, head, dorsum, ears)

What is the best dx for Seb adenitis?

Biopsy

What is tx for Seb adenitis?

Cyclosporine - life long tx

-coat likely will not go back to normal

What is the most common autoimmune skin dz?

Pemphagus foliaceaus

What is Pemphagus foliaceaus characterized by ?

Acantholysis -> desmoglein 1

What is the most common clinical sign of Pemphagus foliaceaus?

Pustules

Name three other dz processes that present w/ acantholytic keratinocytes?

Dermatophytes

Demodex

Pyoderma

What are Tx of Pemphagus foliaceaus?

Steroids

Azathioprine - not in cats

Atopica

Apoquel

-life long

What is mycosis fungoides?

Cutaneous lymphoma

What is the most common type of cutaneous lymphoma?

T-cell

What age do we see Epitheliotrophic T cell lymphoma?

9-12y - likely to see in dogs who have never had allergy problems

What are clinical signs of epitheliotropic T-cell lymphoma?

Exfoliative erythroderma - red scaling

Depigmentation at mucocutaneous junctions

What are tx for Epitheliotrophic T cell lymphoma?

High dose steroids

Apoquel

What is px for Epitheliotrophic T cell lymphoma?

Poor 6-9m

What are clinical signs of pyoderma?

Epidermal collerets/ crusts

Pustules

Who gets pyoderma more commonly dogs or cats?

Dogs

How do you dx pyoderma/ malassezia?

Cytology

What is the most common bacteria of secondary skin infection?

Staphylococcus psuedointermedius

What are 4 indications for culturing a skin infection?

Rod shaped

Failure to respond to therapy

Immunocompromised O

Service dog

You should typically start with _____ tx for pyoderma and malassezia?

Topical

What are a few emprical abx tx for pyoderma?

Cephalosporin

Pen

Lincosamides

Macrolides

How long should you tx a pyoderma infection?

Until gone 21-30 days

RECHECKS w/ cytology are important!!!!

What is the only malassezia that is not lipid dypendent?

malassezia pachydermatitis

What are clinical signs of malassezia?

Lichanification

Hyperpigment

Erythema

What are first line therapys for malassezia?

Miconazole

Climbazole

Ketoconalzoe

Chlorohex

TOPICAL!!!

malassezia in a cat is suggestive of what?

Paraneoplastic syndrome