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ectoderm
nervous system, epithelial cells
mesoderm
connective tissue, epithelial cells
endoderm
lining of organs, epithelial cells
mesenchymal cells are found in…
the mesoderm
matrix is composed of
ground substances and fibers
functions of connective tissue
enclosing/separating
connecting
supporting/moving
storage
cushioning/insulation
transporting
protecting
connective tissue types
connective tissue proper
fluid connective tissue
supporting connective tissue
connective tissue proper types
dense: organized, tightly packed
loose: dispersed, open
fluid connective tissue types
blood: sometimes has fiber (fibrous clot when cut), flows with cardiovascular system
lymph: flows with the lymphatic system
supporting connective tissue types
cartilage: solid, rubbery matrix (hyaline, elastic, fibrous)
bone: solid
there are no blood cells in epithelial cells meaning they are…
avascular
epithelial cells in get nourishment from…
connective tissue
mesenchyme derived cells (-blast) means
they’re capable of mitosis
mesenchyme derived cells (-cyte) means
they’re beyond mitosis
collagen fibers
strongest and largest fiber
3 wrapped proteins
elastic fibers
medium size, elasticity
reticular fibers
smallest/thinnest fiber
dsytrophic epidermolysis bullosa
defect in a gene that codes for collagen; collagen typically connects to epithelial cells underling connective tissue
Marfan’s syndrome
defect in elastin by fibrillin protein
ground substance is made of
interstitial fluid, cell adhesion molecules, proteoglycans and GAGs (e.g. hyaluronic acid, fibrous capsule, chondroitin surface
loose (areolar) CT
collagen (pink)
fibroblasts (make collagen)
fat cells
blood cells
mast cells (inflammatory signal)
capillary
macrophage (big eater)
white fat cells
fat pushes to edges and leaves a thin layer of cytosol (one fat cell)
brown fat cells
have a lot of mitochondria that break down sugar and generate heat (multiple fat cells)
non-shivering thermogenesis
reticular tissue
liver, spleen
blood cells, reticular fibers
dense regular connective tissue
collagen fibers are tightly packed, going in the same direction
wraps around muscles
dense irregular connective tissue
collagen fiber in all different directions
very tough collagen fiber
elastic tissue
elastic fibers, recoil after stretching
connecting vertebrae, elastic arteries near heart
red blood cells
no nucleus, carry oxygen via hemoglobin
white blood cells
granulocytes (neutrophil, basophil, eosinophil) & agranulocytes (monocyte, lymphocytes)
platelets
fragments of a blood cell that help form blood clots
types of supportive connective tissue
hyaline cartilage
elastic cartilage
fibrocartilage
hyaline cartilage
ribs connect to sternum, trachea
chondrocyytes in lacuna
no blood vessels (avascular)
interstitial growth
grows innwards to outwards
appositional growth
grows top to bottom
elastic cartilage
maintains shape while allowing great flexibility
chondrocytes in lacuna
ear, tip of nose
fibrocartilage
collagen fibers provide strength to absorb compressive shocks
intervertebral discs
have chondrocytes in lacuna
bone
vascular
central canal contains blood vessels to provide oxygen and nutrients
gap junctions between osteocytes to share oxygen/nutrients
1/3 organic material (cells and collagen)
2/3 inorganic material (calcium and phosphate)
One difference between bone and cartilage is that
Only bone is vascularized
The most abundant protein in connective tissue is
Collagen
Non-shivering thermogenesis is a function of
Brown fat cells
Marfan’s syndrome
Is a genetic condition caused by a defect in elastin associated protein called fibrillin
skeletal muscle
striated (striped) pattern of actin and myosin
multi-nucleated, so they can make protein, repair self, and grow
voluntary (muscles need message from NS in order to contract)
acting and myosin contract directly over top each other
smooth muscle
not striated (actin and myosin are arranged randomly)
contracting in all directions, not just directly overlapping
uni-nucleated
involuntary (controlled by hormones or autonomic NS)
cardiac muscle
striated (striped) pattern of actin and myosin
intercalated discs: junctions between cells
desmosomes: lock cells together
gap junctions: allow ions to travel between cells
uni-nucelated
involuntary (pacemaker cells: establish rhythm of contractions)
affected by hormones and autonomic NS (sympathetic, parasympathetic)
nervous tissue contains
neurons and neuoglia cells that are derived from the ectoderm
dendrites of a neuron
receives signals
neurotransmitter
released by axon terminal
chemical messenger that is specific to each neuron
what transports neurotransmitters and requires ATP?
networks of microtubules
what are the four membranes composed of? to make them what?
connective tissue and epithelial cells, making them organs
cutaneous membrane
skin, epithelial tissue (top) and connective tissue (bottom)
areolar tissue and dense irregular tissue
protection from outside world
mucous membrane
lines the mouth and digestive system
produces mucus
open to the outside world (ingesting things)
serous membrane
double-membrane (visceral: organ, parietal: outside, and serous fluid in between)
enclosed space
creates lubricating surface to smooth/cushion movement of organs
synovial membrane
produces serous fluid to protect cartilage/bone from rubbing together and creating pain
closed membrane, located at joint capsules
superficial fascia
hypodermis, CT (areolar, adipose)
deep fascia
dense connective tissue
subserous fascia
areolar tissue
injury and repair are initiated by…
inflammatory response (makes body aware)
areolar connective tissue has mast cells that release:
heparin
histamine
serotonin
leukotrienes
bradykinins
all inflammatory responses cause…
vasodilation (redness, heat, swelling, pain, lack of function)
in the regeneration of damaged tissue…
inflammation initiatates healing response
new blood vessels need to grow into the area
macrophages are important in the cleanup of debris and elimination of pathogens
Which cells show striations and are multi-nucleated?
skeletal muscle
Which embryonic layer gives rise to the cells of the nervous system?
Ectoderm
What tissue lies directly under the epithelial layer of a membrane?
Areolar connective tissue
In the regeneration of damaged tissue…
All of the above