Pharmacology Week 1

Drug

A chemical or substance that alters a physiological or biochemical process in the body

A chemical or substance that alters a physiological or biochemical process in the body

Drug

Medicine

Preparation that is used with therapeutic intent - to prevent or treat disease

Preparation that is used with therapeutic intent - to prevent or treat disease

Medicine

Pharmacokinetics

What the body does to the drug

Pharmacodynamics

What the drug does to the body

What does an agonist do?

Binds to the target and activates it, producing a response (mimics the body’s own molecule)

What binds to the target and activates it, producing a response (mimics the body’s own molecule)?

An agonist

What does an antagonist do?

Binds to the target but does NOT activate it (by occupying the site, it blocks the body’s own molecule from acting on it)

What binds to the target but does NOT activate it (by occupying the site, it blocks the body’s own molecule from acting on it)?

An antagonist

What is the enteral route?

Via the GI tract

What is the route that goes through the GI tract?

The enteral route

What is the parenteral route?

Bypassing the GI tract

What is the route that bypasses the GI tract?

The parenteral route

What are the 5 routes of administration?

Oral (PO), intravenous (IV), intramuscular/subcutaneous (IM/SC), inhaled, topical/transdermal

What are the 4 molecular targets?

• Enzymes

• Transporters/carrier molecules

• Ion channels

• Receptors

What are receptors?

Protein structures that receive your body’s chemical signals

What are protein structures that receive your body’s chemical signals?

Receptors

What are enzymes?

Proteins that catalyse reactions

What are proteins that catalyse reactions?

Enzymes

What are ion channels?

Proteins that control flow of ions across cell membranes

What are proteins that control flow of ions across cell membranes?

Ion channels

What are transporters?

Proteins that carry molecules across cell membranes

What are proteins that carry molecules across cell membranes called?

Transporters

What does the TGA do?

Evaluate, register, regulate manufacturing, monitors post-approval

What is The Poisons Standard?

National system used to classify substances by access control

What is the national system used to classify substances by access control?

The Poisons Standard

To authorise a medicine for a particular patient

Prescribe

To prescribe is to

Authorise a medicine for a particular patient

To provide the medicine to the patient

Supply/dispense

To supply/dispense is to

Provide the medicine to the patient

To give the medicine to the patient

Administer

To administer is to

Give the medicine to the patient