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Rose - Sick individuals and sick populations

  • Case-centered epidemiology identifies individual susceptibility, but it may fail to identify the underlying causes of incidence

  • The high-risk strategy of prevention is an interim expedient, needed in order to protect susceptible individuals, but only for so long as the underlying causes of incidence remain unknown or uncontrollable; if causes can be removed, susceptibility ceases to matter

  • The priority of concern should always be the discovery and control of the causes of incidence

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