Kelsey Kendellen, PhD
Summarize the physical changes that occur in old age
Describe menopause
Identify the pros & cons of hormone replacement therapy (HRT)
Average shrinkage: 1/4 to 1/3 inch per decade after 40
Men: lose ~0.5 inch from ages 30 to 50; additional ¾ inch from 50 to 70
Women: lose approximately 2 inches over 50 years (ages 25 to 75)
Causes of shrinkage:
Loss of fluid in discs between vertebrae (spine shrinks)
Loss of muscle mass contributing to poor posture
Increase in the percentage of overweight/obese adults from early to late adulthood:
18-34 years: 31%
50-64 years: 39%
65+ years: 39%
Overweight and obesity correlate with increased risks for:
Type 2 diabetes
High blood pressure
Heart disease (Source: Statistics Canada, 2021)
Sarcopenia:
Age-related loss of muscle mass and strength
Maximum physical strength occurs in 20s
After age 50, muscle loss is approximately 1-2% per year
Decreased muscle mass can lead to a “sagging” appearance
Osteoporosis:
Extensive loss of bone mass and tissue
Commonly referred to as the “silent thief”
Most susceptible: older women post-menopause due to decreased estrogen levels
Common fracture sites: hip, spine, wrist, and shoulder
Arthritis:
Inflammation of joints leading to pain, stiffness, and movement difficulties
Approximately 1 in 5 Canadians live with arthritis
Degeneration of protective cartilage and joint fluid, making movement painful
Autoimmune disorder where the body attacks its own joint tissues
Usually affects parallel joints on both sides of the body
Decline in all five senses with aging:
Vision
Presbyopia: gradual loss of ability to focus on nearby objects starting in early/middle adulthood
Significant vision decline in late adulthood, especially in contrast sensitivity and glare tolerance
Age-Related Macular Degeneration (AMD): deterioration of the macula leads to loss of central vision, sparing peripheral vision
Cataracts result in cloudy or opaque lens, can progress to blindness
Hearing
Hearing loss begins by age 40, affecting ability to hear high frequencies
Men generally lose sensitivity sooner than women
Smell and Taste
Loss starts around age 60 due to fewer taste buds and changes in brain structure
Touch and Pain
While touch sensitivity declines, many older adults report persistent pain, primarily back pain, peripheral neuropathy, and chronic joint pain
Definition: the cessation of menstrual periods, marks the end of reproductive years
Menopause is influenced by hormonal changes:
Ovaries stop releasing eggs monthly
Decrease in estrogen and progesterone levels
Occurs after 12 consecutive months without a period
Typical age range: around 51, but may vary (45-55)
Perimenopause: 6-8 years prior to menopause, gradual decrease in estrogen production
Premature menopause occurs in 1 in 100 women before age 40, can be due to genetics, metabolic issues, or autoimmune conditions
Can be a result of surgical removal of ovaries, chemotherapy, or pelvic radiation
Symptoms may be more intense than natural menopause
Fluctuating hormonal levels lead to:
Irregular periods
Memory loss
Joint aches
Changes in sexual desire and vaginal dryness
Hot flashes, fatigue, sleep disruption, mood swings
75% of women report symptoms affecting their daily lives
Estrogen-only: for women without a uterus
Combined HRT: estrogen plus progestin, available in various forms (patches, pills, creams, etc.)
Benefits:
Effective for vasomotor symptoms (hot flashes) and genitourinary issues
Helps maintain bone density and improve quality of life
Risks:
Long-term combined HRT (5+ years) associated with:
Increased risks of breast & ovarian cancer, heart disease, stroke, and pulmonary embolism
HRT should be individualized based on severity of symptoms and health status
Not recommended if there’s a history of specific cancers or cardiovascular issues
Best suited for healthy women under 60 who have been menopausal for less than 10 years
Gradual decline in testosterone levels by approximately 1% per year after age 40
By age 70, testosterone levels can drop to 30% below peak
Most men maintain fertility through middle age
Age affects semen parameters:
Sperm concentration, volume, and motility decline with age
Total sperm count = sperm concentration x volume of ejaculation
Sperm motility (ability to swim) is key for fertility