What are the two primary divisions of the nervous system?
Central Nervous System (CNS) and Peripheral Nervous System (PNS)
What are the components for the CNS?
brain and spinal cord
What are the components for the PNS?
Cranial Nerves, 31 pairs of spinal nerves
The __________ is the _____________ unit of the nervous system
Neurons, functional
What are the 5 types of neuroglial cells discussed in lecture?
Oligodendrocytes, Microglia, Astrocytes, Ependymal cells, Schwann cells
What is the function of oligodendrocytes?
form myelin in CNS
What is the function of Microglia?
immune function;protect the brain from damage and infection
What is the function of Astrocytes?
form blood brain barrier
What is the function of Ependymall cells?
produce cerebral spinal fluid
What is the function of Schwann cells?
produce myelin in PNS
What are the 4 parts of a neuron?
cell body, dendrites, axon, axon terminals
What is the function of the cell body(soma) in a neuron?
responsible for maintaining the neuron's structure and carrying out metabolic functions (contains nucleus)
What is the function of the dendrites in a neuron?
receive incoming signals from other neurons
What is the function of the Axon in a neuron?
It carries messages away from the cell body.
What is the function of the Axon terminal in a neuron?
forms a synapse with another neuron or a target cell. It contains vesicles filled with neurotransmitters that are released into the synapse to communicate with other cells.
Define Nuclei
group of similar neurons within the CNS
Define Ganglia
group of similar neurons within the PNS
What does sensory(afferent) refer to?
sends information to the brain
What does motor(efferent) refer to?
sends information to the body
What nerves can repair themselves to some extent?
Peripheral nerves (nerves outside brain and spinal cord)
What nerves cannot be repaired?
CNS nerves (brain and spinal cord)
What is the blood brain barrier?
a highly selective and semipermable membrane that separates the circulating blood from the brain
How is the blood brain barrier formed?
formed by tightly connected endothelial cells that line the blood vessels in the brain. These cells are tightly connected by tight junctions that prevent most substances from passing between them and are regulated by astrocytes.
What is the function of the blood brain barrier?
serves to protect the brain from harmful substances and pathogens by preventing them from entering the brain tissue.
Describe the maintenance of the resting membrane potential
maintained by sodium (Na+) and potassium (K+) pumps, K+ is diffused outside the cell creating a negative charge inside the cell which attracts positively charged ions that creates an electrochemical gradient that helps maintains a resting membrane potential -70 mv
What is frequency in relations to action potentials?
number of action potentials that occur
What is amplitude in relations to action potentials?
size or magnitude of electrical signals
What is conduction ratein relations to action potentials?
speed at which an action potential travels down an axon
What is saltatory conduction?
"leaping" of action potential from node to node
What neurotransmitter did Otto Loewi actually discover with his vagustuff experiment?
AcetylColine (A Ch)
How important was the discovery by Otto Loewi?
Significant because we discovered that the nervous system communicates both electrically and chemically.
What is the role of acetylcholine esterase?
enzyme that breaks down the neurotransmitter acetylcholine in the synaptic cleft, which helps to terminate signaling between neurons that use acetylcholine as a neurotransmitter.
What is the role of glycine in the brain?
an inhibitory neurotransmitter in the brain and spinal cord that binds to glycine receptors, which are involved in motor control, pain perception, and sleep regulation.
What is the role of GABA in the brain?
inhibitory neurotransmitter in the brain that helps to regulate the activity of neurons by binding to GABA receptors. These receptors are involved in anxiety, sleep, and muscle tone.
What does the term synaptic plasticity refer to?
the strengthening of synapses to encode memories and other information through repeated activity
Long-term potentiation is involved in ________ formation
memory
What does the term "circuit" mean when talking about the brain?
group of interconnected neurons that work together to perform a specific function
What is the function of the Medulla Oblongata?
controls autonomic functions of internal organs. Ex: BP, heart rate, respiratory control
What is the function of the Cerebellum?
controls basic and skilled movements ex: balance, fine cordination
What is the function of the Pons?
connects cerebellum and spinal cord with higher brain centers "Bridge"
What is the function of the Midbrain?
relays visual and auditory inputs
What is the function of the Thalamus?
receives transfers and processes sensory input to higher brain areas for interpretation
What is the function of the Hypothalamus?
controls the endocrine system by connecting to the pineal gland
What is the function of the Limbic system?
emotions and basic pattern of behaviors
What is the function of the Cerebrum?
coordinates movement, decision making , produces thought and speech. The "soul".
What are the 5 lobes of the cerebrum?
frontal, parietal, temporal, occipital lobe and insula
What is the function of the frontal lobe?
voluntary control of muscles/ movement, speech and personality
What is the function of the parietal lobe?
cutaneous and muscular sensations; interpretation of language, speech, textures, shapes
What is the function of the temporal lobe?
interpretation of auditory sensations, memory storage
What is the function of the occipital lobe?
visual integration, and conscious perception of vision
What is the function of the insula?
memory;sensation of pain, visceral integration/ stomach pain
What is the function of Broca's area in regard to speech?
produce language
What is the function of Wernicke's area in regard to speech?
Receives input from the auditory cortex (words you hear) and visual cortex (words you see) to interpret language
What are some functions of the limbicsystem?
Learning, memory, motivational system, emotions important to survival, , regulate hormonal functions
What region of the brain is especially involved in regulating the limbic system and endocrine systems as well as communicating with the medulla obolngata to regulate autonomic functions?
Hypothalamus
What is the the reticular formation responsible for?
Tuning out unimportant sensory stimulation when sleeping and alerting to important stimulation
What are the basic functions of the autonomic nervous system (ANS)?
Regulates autonomic functions such as the heart, blood vessels, smooth muscles, including the muscles of the intestinal tract and glands of the endocrine system
Does the ANS posses motor, sensory or both motor and sensory fibers?
contains both motor and sensory fibers
What two divisions comprise the ANS?
Sympathetic , parasympathetic division
Preganglionic fibers of the sympathetic division originate in the __________ regions whereas preganglionic fibers of the parasympathetic division originate in the ________ and ________ regions
Thoracolumbar, CNS, Craniosacral
Describe the sympathetic division
Activates the body to either deal with a threat "flight" or "flight" through the release norepinephron from postganglionic neurons and epinephrine (adrenaline) from adrenal glands
Describe the Parasympatheticdivision
"Rest and Digest" slowing the heart rate down, dialtion of visceral blood vessels and increased activity of the digestive tract
Sympathetic effect on the heart
Increases heart rate (norepinephron)
Parasympathetic effect on the heart
Decreases heart rate (acetyl choline)
Sympathetic effect on the pupil
Dilates pupil
parasympathetic effect on the pupils
constricts pupil
Sympathetic effect on the Digestive system
inhibits digestion
Parasympathetic effect on the digestion system
stimulates digestion
Sympathetic effect on the Lungs
Increases respiratory rate
Parasympathetic effect on the Lungs
Decreases respiratory rate
Sympathetic effect on the Blood vessels
constricts blood vessels
Parasympathetic effect on the Blood vessels
dilates blood vessels
Sympathetic effect on the bladder
Relaxes bladder muscles
Parasympathetic effect on the bladder
contracts bladder muscles
Sympathetic effect on the Adrenal gland
causes secretion of epinephrine and norepinephrine by adrenal medulla
Parasympathetic effect on the Adrenal gland
no effect