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Comprehensive Study Notes: Atoms, Bonding, Reactions, and Basic Biochemistry

Page 1

  • Atom notation explained

    • ¹¹H means:

    • Atomic number (bottom left) = 1 → 1 proton

    • Mass number (top left) = 1 → 1 proton + 0 neutrons

    • ³₁H means:

    • Atomic number = 1 → 1 proton

    • Mass number = 3 → 1 proton + 2 neutrons

  • Correct Answer: They are isotopes.

    • 💡 Why?

    • Isotopes are atoms of the same element (same number of protons) but different numbers of neutrons.

    • Both atoms are hydrogen (atomic number 1), but:

      • ¹H has 0 neutrons

      • ³H has 2 neutrons

    • So they’re isotopes of hydrogen: specifically, protium (¹H) and tritium (³H).

  • Why the other options are incorrect:

    • Polymers: Polymers are long chains of molecules, not individual atoms.

    • They contain 1 and 3 protons: Both have 1 proton—atomic number defines that.

    • They are compounds: Compounds are made of two or more different elements bonded together. These are single atoms.

    • They each contain 1 neutron: ¹H has 0 neutrons, ³H has 2 neutrons.

  • Atom N: ¹⁴₇N

    • Atomic number = 7 → Nitrogen has 7 protons and 7 electrons (in a neutral atom).

    • 🌀 Electron Configuration of Nitrogen

    • Shell 1 holds 2 electrons

    • Shell 2 holds up to 8 electrons

Page 2

  • The Identity of an Atom

    • The atomic number is what determines the element.

    • Atomic number = number of protons in the nucleus.

    • So…

    • Correct Answer: protons in an atom

  • 💡 Why?

    • If you change the number of protons, you change the atomic number, which means you're now dealing with a completely different element.

    • ○ Example: Carbon has 6 protons → if you add one, it becomes nitrogen (7 protons).

  • Why the other options don’t work:

    • Particles in the nucleus: That includes both protons and neutrons—only changing protons changes the element.

    • Electrons circling the nucleus: Changing electrons affects charge, not the element.

    • Neutrons in an atom: That creates isotopes, not new elements.

  • What determines electron arrangement?

    • The text notes: Electron Configuration of Nitrogen

    • Shells and electron counts lead to understanding valence electrons.

Page 3

  • What are isotopes?

    • Isotopes are atoms of the same element (same number of protons) but with different numbers of neutrons.

    • That means they have the same atomic number, same number of electrons, and same chemical behavior—but different mass numbers.

    • Correct Answer: have different numbers of neutrons

    • Why the other options are incorrect:

    • Different numbers of electrons: Only changes if the atom is an ion—not an isotope.

    • React differently with other atoms: Isotopes of the same element react the same way chemically.

    • Different atomic numbers: That would make them different elements, not isotopes.

  • What makes an atom reactive?

    • Reactivity is all about how eager an atom is to bond with others.

    • That eagerness comes from unpaired electrons in the valence shell (the outermost shell).

    • Atoms “want” to fill or empty their valence shell to become stable—like noble gases.

    • Correct Answer: the existence of unpaired electrons in the valence shell

    • 🔍 Why the other options don’t work:

    • Average distance of the outermost shell: Affects energy levels, but not directly reactivity.

Page 4

  • Potential energy of the valence shell

    • Doesn’t explain why atoms bond—unpaired electrons do.

  • Sum of potential energies of all shells

    • Too broad—reactivity is driven by the outer shell only.

  • Mass number = 15, Atomic number = 7

    • Atomic number = # of protons = 7

    • Mass number = protons + neutrons → So: Neutrons = 15 − 7 = 8

    • Protons repel electrons

    • Nope! Protons are positively charged, electrons are negatively charged → they attract each other.

    • Protons attract other protons

    • Not quite. Protons repel each other because they have the same charge. They're held together in the nucleus by the strong nuclear force, not attraction.

    • Most of an atom's volume is filled with matter

    • Actually, atoms are mostly empty space! The nucleus is tiny, and electrons zip around in a huge cloud.

    • Electrons determine the atom's size

    • Yes! The electron cloud defines how big the atom is. The farther out the electrons orbit, the larger the atom appears.

    • All of the above

Page 5

  • An atom has 8 protons, 8 neutrons, and 8 electrons. Another isotope of the same element might have 10 neutrons.

    • Because only one statement is true, this one’s out.

  • "All the electrons in an atom have similar amounts of energy" False.

    • Electrons in outer shells have more energy than those in inner shells.

  • "The valence shell has higher energy than other occupied shells" True!

  • "Electrons must lose energy to move from the first to the second shell" False.

    • Electrons must gain energy to move to a higher shell, not lose it.

  • "All of the above" Incorrect, since only one statement is true.

  • Given: 6 protons • 6 neutrons • 6 electrons

    • What defines the element?

    • The number of protons = atomic number

    • Atomic number 6 = Carbon (C)

    • Correct Answer: C; it has 6 protons

    • Why the other options don’t work:

    • N; it has 6 electrons: Not enough to define the element; protons define the element.

    • N; it has 6 protons: Not correct for nitrogen.

    • C; it has 6 electrons: True for a neutral atom, but protons define the element.

    • O; its mass number is 12: Oxygen has 8 protons → atomic number 8.

Page 6

  • Chemists assign atoms to chemical elements by counting their protons

  • Which of the following is the key characteristic that is ultimately responsible for the unique chemical properties of each element?

    • Each element has a unique number of protons.

  • 🧪 What is a mole?

    • A mole is a counting unit—like a dozen, but way bigger.

    • 1 mole = 6.022 imes 10^{23} particles (Avogadro’s number)

    • So a mole of anything—sugar, vitamin C, atoms, ions—means you have that many molecules or particles, regardless of their size or mass.

  • Why the other options don’t work:

    • Volume: Different substances have different densities and molecular sizes.

    • Number of atoms: Mole counts vary with molecular size; a mole of different substances won’t have the same total atom count.

    • Mass: Different molecules have different molar masses—so their masses will be different even if you have 1 mole of each.

  • An element is a pure substance made of only one kind of atom. Examples: Carbon (C), Oxygen (O), Hydrogen (H).

  • which of the following is a trace element required by all living organisms?

    • IODINE

  • Radioactive decay happens when an atom’s nucleus is unstable, often due to:

    • Too many neutrons

    • Too few neutrons

    • Imbalance in nuclear forces

    • Correct Answer: Imbalance in nuclear forces

Page 7

  • Which four of the 92 naturally occurring elements make up approximately 96% of the mass of the human body?

    • Carbon, Hydrogen, Nitrogen, Oxygen

  • Trace elements are required by organisms in only minute quantities (less than 0.01% of mass).

  • Which of the following is a trace element that is required by humans and other vertebrates?

    • IODINE

    • Why iodine?

    • Iodine is essential for making thyroid hormones, which regulate metabolism, growth, and development.

    • Deficiency can lead to goiter or other thyroid issues.

  • Why the other options don’t count as trace elements:

    • Nitrogen: Needed in large amounts for proteins and DNA.

    • Calcium: Crucial for bones and muscles—needed in bulk.

    • Phosphorus: Key part of DNA, ATP, and bones—also needed in large amounts.

    • Potassium: Vital for nerve and muscle function—required in significant amounts.

  • Trace elements are required by organisms in only minute quantities (less than 0.01% of mass).

  • Which of the following is a trace element that is required by all organisms? IRON

  • Given only a mass number, one can deduce the number of in each atom of an element. What is the mass number?

    • Mass number = protons + neutrons

Page 8

  • It tells you the total number of particles in the nucleus, but not how many of each.

    • Correct Answer: protons plus neutrons

    • Why the other options don’t work:

    • Neutrons: You need the atomic number (protons) to subtract from the mass number.

    • Protons: Mass number alone doesn’t tell you how many protons—need atomic number.

    • Electrons: Only equal to protons in a neutral atom, and mass number doesn’t include electrons.

    • Protons plus electrons: Mass number doesn’t include electrons at all—just nucleus particles.

  • Oxygen has an atomic number of 8 and a mass number of 16. What is the atomic mass of an oxygen atom?

    • Given: Atomic number = 8 → 8 protons; Mass number = 16 → 8 protons + 8 neutrons

    • What is atomic mass measured in?

    • Atomic mass is typically expressed in daltons (Da) or atomic mass units (amu).

    • 1 proton ≈ 1 dalton, 1 neutron ≈ 1 dalton

    • So: 8 protons + 8 neutrons = ~16 daltons

    • Correct Answer: approximately 16 daltons

    • Why the other options don’t work:

    • 8 daltons: That’s just the number of protons—not the full mass.

  • Protons repel electrons

    • Protons repel electrons

  • Protons attract other protons

    • Not quite. Protons repel each other because they have the same charge. They’re held together in the nucleus by the strong nuclear force, not attraction.

  • Most of an atom's volume is filled with matter

    • Actually, atoms are mostly empty space! The nucleus is tiny, and electrons zip around in a huge cloud.

  • Electrons determine the atom's size

    • Yes, the electron cloud defines how big the atom is.

Page 9

  • An atom has 16 protons, 16 neutrons, and 16 electrons? (Example context from decay section)

  • 16 grams Way too large—grams are used for moles, not single atoms.

  • 24 daltons That would mean extra neutrons—not true for oxygen-16.

  • 8 grams Again, grams are for bulk amounts, not individual atoms.

  • 🧪 What’s happening in this decay?

    • Phosphorus-32 has:

    • 15 protons (atomic number)

    • 17 neutrons (mass number 32 − 15)

    • In beta decay, a neutron turns into a proton, and an electron (beta particle) is emitted.

    • 🔄 What changes?

    • The atom gains 1 proton → atomic number increases from 15 to 16

    • Mass number stays the same → still 32

    • So the new atom has:

    • 16 protons

    • 16 neutrons

    • Mass number = 32

    • Correct Answer: sulfur-32 (atomic number 16)

    • Why the other options don’t work:

    • Negatively charged phosphorus-32 ion: This isn’t ionization—it’s nuclear decay.

    • Phosphorus-31: That’s a different isotope, not the result of this decay.

    • Positively charged phosphorus-31 ion: Wrong isotope and wrong process—this isn’t about losing electrons.

Page 10

  • The chemical behavior of an atom depends primarily upon which of the following?

    • Correct Answer: the number of electrons in the valence shell

    • 💡 Why?

    • The valence shell is the outermost electron shell.

    • The number of electrons in that shell determines how an atom bonds, reacts, and interacts with other atoms.

    • Atoms with full valence shells (like noble gases) are stable and unreactive.

    • Atoms with unpaired or missing electrons in the valence shell are more reactive.

  • Why the other options don’t work:

    • Number of protons: Defines the element, but not its chemical behavior.

    • Total number of electrons: Doesn’t matter unless you know how they’re arranged.

    • Number of electron shells: Affects size and energy, but not reactivity directly.

    • Number of neutrons: Influences isotopes and stability, not chemical behavior.

  • How does the formation of covalent bonds differ from the formation of ionic bonds between two atoms?

    • Correct Answer: Covalent bonds involve the sharing of electrons between atoms; ionic bonds involve the transfer of electrons from one atom to the other.

    • 🔬 Why this is correct:

    • Covalent bonds: Atoms share electrons to fill their valence shells. Example: In H₂O, oxygen shares electrons with hydrogen.

    • Ionic bonds: One atom transfers electrons to another, creating charged ions that attract each other. Example: In NaCl, sodium gives up an electron to chlorine → Na⁺ and Cl⁻ attract.

    • Why the other options don’t work:

    • Sharing of pairs vs. single electrons: Covalent bonds can involve sharing of electron pairs; ionic bonds don’t involve sharing at all.

    • Molecules vs. compounds: Both covalent and ionic bonds can form compounds; this doesn’t explain the bonding mechanism.

    • Transfer vs. electrical attraction: Ionic bonds do involve electrical attraction—but only after the electron transfer. The key difference is sharing vs. transferring.

Page 11

  • Chemical equilibrium is reached when __.

    • Correct Answer: the forward and reverse reactions occur at the same rate so that the concentrations of reactants and products have stabilized at a particular ratio.

    • 💡 Why?

    • Chemical equilibrium doesn’t mean the reaction stops—it means the rate of the forward reaction equals the rate of the reverse reaction.

    • The concentrations of reactants and products stay constant, but not necessarily equal.

    • It’s a dynamic balance, not a freeze-frame.

    • Why the other options don’t work:

    • Matter destroyed/created: Not correct—law of conservation.

    • Reverse reaction begins: That can happen before equilibrium is reached.

    • All reactants converted: That's completion, not equilibrium.

    • Matter is conserved: True in general, but not specific to equilibrium.

  • Which of the following correctly describes any chemical reaction that has reached equilibrium?

    • Correct Answer: The rate of the forward reaction is equal to the rate of the reverse reaction

    • 💡 Why?

    • At chemical equilibrium, the reaction doesn’t stop—it just reaches a point where the forward and reverse reactions happen at the same rate.

    • The concentrations of reactants and products remain constant, but they don’t have to be equal.

    • It’s a dynamic balance, not a complete conversion or freeze.

    • Why the other options don’t work:

    • The reaction is now irreversible: No, equilibrium is reversible.

    • Concentrations are equal: Not necessarily—just stable, not equal.

    • Both reactions have halted: False—they’re still happening, just at equal rates.

Page 12

  • Water molecules have a polarity, which allows them to be electrically attracted to other water molecules and other polar molecules by weak chemical bonds known as _.

    • Correct Answer: hydrogen bonds

    • 💡 Why?

    • Water is polar:

      • Oxygen pulls electrons more strongly, creating partial negative charge on O and partial positive charges on H.

    • This polarity allows water molecules to form weak attractions between the partially positive hydrogen of one molecule and the partially negative oxygen of another.

    • These weak attractions are hydrogen bonds and are responsible for water’s properties.

    • Why the other options don’t work:

    • Nonpolar covalent bonds: Involve equal sharing of electrons—water is polar.

    • Van der Waals interactions: Very weak and non-specific—not the main force between water molecules.

    • Polar covalent bonds: True within a water molecule, but not between molecules.

    • Ionic bonds: Involve full electron transfer—not relevant to water’s intermolecular bonding.

  • Many of water's emergent properties, such as its cohesion, its high specific heat, and its high heat of vaporization, result from the fact that water molecules _.

    • Correct Answer: are attracted to each other by partial negative and positive charges on the oxygen and hydrogen atoms, respectively

    • 💡 Why?

    • Water is a polar molecule:

      • Oxygen has a partial negative charge

      • Hydrogen has a partial positive charge

    • This polarity allows water molecules to form hydrogen bonds with each other.

    • Why the other options don’t work:

    • Very small: True, but not the cause of those specific properties.

    • Extremely large: False—water is a small molecule.

    • In constant motion: Also true, but not the direct cause.

    • Tend to repel each other: No—water molecules attract via hydrogen bonding.

  • An acid is a substance that _.

    • Correct Answer: increases the hydrogen ion concentration of an aqueous solution

    • 💡 Why?

    • Acids release H⁺ ions (hydrogen ions) when dissolved in water.

    • This increase in hydrogen ion concentration is what gives acids their low pH and characteristic reactivity.

    • Example: HCl (hydrochloric acid) → dissolves in water → H⁺ + Cl⁻

    • Why the other options don’t work:

    • Forms covalent bonds: Not unique to acids.

    • Reduces hydrogen ion concentration: That’s what bases do.

    • Is a versatile solvent: Water is a solvent, not acids in general.

    • Contains hydrogen: True, but not all hydrogen-containing substances are acids.

  • pH of 6 is how many times more acidic than a pH of 9?

    • How the pH scale works:

    • The pH scale is logarithmic, meaning each unit change = 10× difference in hydrogen ion concentration.

    • So going from pH 9 to pH 6 is a 3-unit drop → 10^3 = 1000

    • Correct Answer: 1,000

    • 💡 What this means:

    • A solution with pH 6 is 1,000 times more acidic than one with pH 9.

    • That’s why even small changes in pH can have big biological effects—especially in enzymes and cellular processes.

  • Q uestion Correct Answer Why It’s Right

    • 1 cohesion

    • 2 hydrogen bonds

    • 3 neutral

    • 4 100 times more acidic

    • 5 An increase in hydrogen ion concentration means a decrease in pH scale units.

    • 6 A solution that could buffer the bleach and ammonia would remove excess OH⁻ ions.

    • 7 Chlorine is filling its third electron shell. Chlorine gains an electron to complete its outer shell.

    • 8 between an oxygen and a hydrogen atom of different water molecules. Hydrogen bonds form between molecules, not within.

    • 9 Oxygen is more electronegative than the hydrogen atoms. It pulls electrons closer, making water polar.

    • 10 polar covalent

    • 11 (Bonus) two polar covalent bonds

    • 12 (Bonus) polar covalent …………. hydrogen

Page 13

  • Water’s emergent properties are driven by hydrogen bonding between water molecules.

  • Hydrogen bonds: weak attractions between the partially positive H and partially negative O of neighboring water molecules.

  • Water’s polarity underlies its solvent abilities and many of its unique properties (cohesion, surface tension, heat capacity, etc.).

  • The term “polarity” arises from unequal sharing of electrons in a polar covalent bond within a water molecule.

Page 14

  • An acid is a substance that increases the hydrogen ion concentration of an aqueous solution. (Re-stated)

  • The pH scale is logarithmic: a change of 1 pH unit corresponds to a 10× change in [H⁺].

  • If pH goes from 9 to 6, the solution becomes 1000× more acidic.

  • Buffers help stabilize pH by neutralizing excess OH⁻ or H⁺ ions.

  • Chlorine is filling its third electron shell; it gains an electron to complete its outer shell when forming ions.

  • Hydrogen bonding explanations: Bonds form between a hydrogen atom and an electronegative atom (like oxygen) in a different molecule (intermolecular) rather than within the same molecule.

  • Some Q&A highlights:

    • Between an oxygen and a hydrogen atom of different water molecules — Hydrogen bonds.

    • Oxygen is more electronegative than hydrogen; this causes polarity in H₂O.

    • Polar covalent bonds are the intra-molecular bonds in H₂O; hydrogen bonds are the inter-molecular bonds.

Page 15

  • Hydration, cohesion, and surface tension in water are linked to hydrogen bonding.

  • Cohesion is water molecules sticking to each other due to hydrogen bonding.

  • Hydrogen bonds contribute to water’s high surface tension and heat-related properties.

  • pH and acidity basics recap: A decrease in pH means an increase in hydrogen ion concentration.

  • Buffers: stabilize pH by neutralizing extra OH⁻ or H⁺ ions as needed.

  • Example questions reviewed (via answers):

    • 1 cohesion

    • 2 hydrogen bonds

    • 3 neutral

    • 4 1000× more acidic

    • 5 More H⁺ → lower pH

    • 6 Buffers neutralize OH⁻ ions

    • 7 Chlorine gains electron to complete outer shell

    • 8 Hydrogen bonds form between molecules

    • 9 Oxygen is more electronegative → water is polar

    • 10 Polar covalent bonds

    • 11 Two polar covalent bonds

    • 12 Polar covalent… hydrogen (hydrogen bonds)

Page 16

  • Additional item clarifications:

    • 7. Chlorine gaining an electron to complete its outer shell reflects achieving a stable electron configuration.

    • 8. Hydrogen bonds occur between molecules (intermolecular).

    • 9. Oxygen’s electronegativity creates polarity in water.

    1. Polar covalent bonds are the intra-molecular bonds in H₂O.

    1. Two polar covalent bonds exist within a water molecule (H–O and H–O).

    1. Between polar covalent (within molecule) and hydrogen bonds (between molecules).

Page 17

  • Lactose and digestion basics:

    • Lactose intolerance = lack of lactase enzyme → can't break down lactose (milk sugar).

  • Organic compounds are defined by the presence of carbon atoms.

  • Carbon can form up to four covalent bonds (not six).

  • Hydrocarbons are organic compounds (not inorganic).

Page 18

  • Isomers: same molecular formula, different structures → different properties.

  • Hydroxyl group (-OH) is found in alcohols.

  • Carboxyl group (-COOH) is a carbon double-bonded to oxygen and single-bonded to hydroxyl.

  • Amino group (-NH₂) found in amino acids and proteins.

  • Amino acids contain both carboxyl (-COOH) and amino (-NH₂) groups.

  • Disaccharides form when two monosaccharides link and release water (dehydration synthesis).

  • Digestion versus dehydration synthesis:

    • Digestion uses hydrolysis to break bonds (water-involved).

  • Example notes:

    • Most animals cannot break down cellulose; starch is easier to digest because cellulose has β-linkages that many animals cannot digest, whereas starch has α-linkages that are easier to digest.

  • Fats have long nonpolar hydrocarbon chains, making them hydrophobic.

  • Summary of key ideas:

    • Hydrophobic vs hydrophilic properties influence solubility and membrane behavior.

Page 19

  • Lipids and their features:

    • 3 Hydrophobic: fatty acid chains repel water.

    • 4 Unsaturated: double bonds introduce kinks; usually liquid at room temperature.

    • 5 Phospholipid basics: one glycerol, one phosphate group, and two fatty acids. This is the basic structure of a phospholipid, key to cell membranes.

    • 6 Steroids: lipids with a four-ring structure (e.g., cholesterol).

    • 7 Phospholipids: form the bilayer of cell membranes — hydrophilic heads, hydrophobic tails.

  • Enzymes and proteins:

    • 8 Enzymes speed up chemical reactions by lowering activation energy.

    • 9 The chemical properties of their R groups (side chains) determine each amino acid’s traits.

    • 10 The sequence of amino acids in the polypeptide chain determines the protein’s shape and function.

    • 11 (Bonus) Peptide bonds form between amino acids during protein synthesis.

    • 12 (Bonus) The primary structure — the sequence of amino acids in the polypeptide chain — is foundational for protein folding and higher structures (secondary, tertiary, quaternary).

Page 20

  • The central dogma of molecular biology:

    • DNA → RNA → Protein

    • The genes in DNA direct the synthesis of an RNA molecule, which is used to build (direct the synthesis of) a protein.

    • Central dogma summary: DNA is transcribed to RNA, which is translated into protein.

Study guide:

  • DNA (Deoxyribonucleic Acid): The molecule that carries genetic information in cells.

  • RNA (Ribonucleic Acid): A single-stranded molecule that plays a crucial role in coding, decoding, regulation, and expression of genes.

  • Protein: Large, complex molecules essential for the structure, function, and regulation of the body's cells, tissues, and organs.

  • Transcription: The process of copying a segment of DNA into RNA.

  • Translation: The process wherein RNA is decoded by a ribosome to produce a specific polypeptide or amino acid chain, ultimately folding into a functional protein.

I. Atom Structure and Identity
  • Atom Notation

    • Atomic number (bottom left): number of protons (defines the element).

    • Mass number (top left): number of protons + neutrons.

  • Isotopes

    • Same element (same protons), different number of neutrons.

    • Example: ¹H (protium, 0 neutrons) and ³H (tritium, 2 neutrons).

    • They have the same atomic number, same electrons, same chemical behavior, but different mass numbers.

  • Determining Element Identity

    • The atomic number (number of protons) defines the element.

    • Changing the number of protons changes the element.

    • Example: Carbon (6 protons) + 1 proton = Nitrogen (7 protons).

  • Electron Arrangement

    • Electrons occupy shells, determining electron configuration and valence electrons.

    • "The valence shell has higher energy than other occupied shells" - True.

  • Reactivity

    • Determined by the existence of unpaired electrons in the valence shell.

    • Atoms aim to fill or empty their valence shell for stability.

  • Atomic Mass

    • Measured in daltons (Da) or atomic mass units (amu).

    • 1 \text{ proton} \approx 1 \text{ dalton}, 1 \text{ neutron} \approx 1 \text{ dalton}.

    • Example: Oxygen (8 protons, 8 neutrons) has an atomic mass of approximately 16 daltons.

II. Atomic Interactions and Properties
  • Subatomic Particle Roles

    • Protons: Positive charge, repel each other but held by strong nuclear force, define the element.

    • Electrons: Negative charge, attract protons, determine the atom's size (electron cloud).

    • Neutrons: No charge, affect mass number and isotopes.

  • Radioactive Decay

    • Occurs when an atom’s nucleus is unstable due to an imbalance in nuclear forces (e.g., too many or too few neutrons).

    • Example: Beta decay of Phosphorus-32 (15 protons, 17 neutrons) → neutron turns into proton → Sulfur-32 (16 protons, 16 neutrons).

  • Mole Concept

    • A counting unit: 1 mole = 6.022 \times 10^{23} particles (Avogadro’s number).

III. Elements and Life
  • Elements in Human Body

    • Carbon, Hydrogen, Nitrogen, Oxygen make up ~96% of human body mass.

  • Trace Elements

    • Required in minute quantities (less than 0.01% of mass).

    • Iodine: Essential for thyroid hormones.

    • Iron: Required by all organisms.

IV. Chemical Bonding and Water
  • Chemical Behavior

    • Primarily depends on the number of electrons in the valence shell.

  • Covalent Bonds

    • Involve the sharing of electrons between atoms.

  • Ionic Bonds

    • Involve the transfer of electrons from one atom to another, creating charged ions.

  • Water Properties

    • Polar molecule: Oxygen is more electronegative than hydrogen, creating partial negative charge on O and partial positive charges on H.

    • Hydrogen bonds: Weak attractions between partially positive H of one water molecule and partially negative O of another.

    • Responsible for water's emergent properties: cohesion, high specific heat, high heat of vaporization, solvation abilities.

V. Acids, Bases, and pH
  • Acid

    • Increases the hydrogen ion (H⁺) concentration of an aqueous solution.

  • pH Scale

    • Logarithmic scale where each unit change is a 10\times difference in H⁺ concentration.

    • Example: pH 6 is 1,000 times more acidic than pH 9 (10^3 difference).

  • Buffers

    • Stabilize pH by neutralizing excess OH⁻ or H⁺ ions.

VI. Organic Molecules
  • Organic Compounds

    • Defined by the presence of carbon atoms.

    • Carbon can form up to four covalent bonds.

  • Functional Groups

    • Hydroxyl group (-OH): Found in alcohols.

    • Carboxyl group (-COOH): Carbon double-bonded to oxygen and single-bonded to hydroxyl (found in fatty acids, amino acids).

    • Amino group (-NH₂): Found in amino acids and proteins.

  • Carbohydrates

    • Monosaccharides: Simple sugars.

    • Disaccharides: Formed by linking two monosaccharides via dehydration synthesis (releases water).

    • Digestion: Uses hydrolysis (adds water) to break bonds.

    • Cellulose vs. Starch: Cellulose has β-linkages (hard to digest), starch has α-linkages (easier to digest).

  • Lipids

    • Hydrophobic: Long nonpolar hydrocarbon chains.

    • Fats: Often saturated (solid at room temp) or unsaturated (double bonds, kinks, liquid at room temp).

    • Phospholipids: Glycerol + phosphate group + two fatty acids; form cell membrane bilayer (hydrophilic heads, hydrophobic tails).

    • Steroids: Lipids with a four-ring structure (e.g., cholesterol).

  • Proteins

    • Made of amino acids (contain both -COOH and -NH₂ groups).

    • R groups (side chains): Determine amino acid traits.

    • Peptide bonds: Form between amino acids during protein synthesis.

    • Primary structure: Sequence of amino acids, foundational for protein shape and function.

    • Enzymes: Proteins that speed up chemical reactions by lowering activation energy.

VII. Central Dogma
  • DNA → RNA → Protein

    • Genes in DNA direct RNA synthesis (transcription).

    • RNA directs protein synthesis (translation).