Actin filaments

formin- nucleates assembly and remains associated with the growing plus end

thymosin- binds subunits, prevents assembly

tropomodulin- prevents assembly and disassembly at minus end

cofilin- binds ADP-actin filaments, accelerates disassembly

Gelsolin- severs filaments and binds to plus end

Capping proteins- prevents assembly and disassembly at plus end

Tropomyosin- stabilizes filament, modulates binding of other accessory proteins

Profilin- binds monomers, concentrates them at sites of filament assembly

Arp2/3 complex- nucleates assembly to form a branched network and remains associated with the minus end

actin filament- filament bundling, cross-linking, and attachment to membranes

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