nervous system 2425 for moodle pre session
Nicholas de Mora-Mieszkowski
The Nervous System
AHP 401 Introduction to Life Sciences
Identify anatomical structures and components of the nervous system.
Describe physiological functions and mechanisms of the nervous system.
Explain physiology associated with the sensation of pain.
Discuss pathophysiological changes due to common illnesses, diseases, injuries, and conditions of the nervous system.
Recap anatomy from pre-session activities.
Discuss physiological functions.
Examine physiology of pain.
Address muddiest points.
Review pathophysiological functional changes in common conditions/illnesses/injuries/diseases.
Cells and Tissues:
Neurones: Basic units of the nervous system conducting impulses.
Neuroglia: Supporting cells that provide insulation and support to neurons.
Central Nervous System (CNS):
Brain
Spinal Cord
Meninges & Cerebrospinal Fluid
Peripheral Nervous System (PNS):
Spinal nerves
Thoracic nerves
Cranial nerves
Autonomic nervous system
Neurones: Specialized cells conducting nerve impulses. Comprising a cell body, axon, and dendrites.
Neuroglia: Group of supporting cells that insulate and support neurons.
Dendrite: Receives signals from other neurons.
Nucleus: Control center of the cell.
Axon: Transmits impulses away from the neuron.
Cell Body: Contains the nucleus and organelles.
Myelin Sheath: Insulating layer around the axon.
Schwann's Cell: Cell forming the myelin sheath in the PNS.
Node of Ranvier: Gaps in the myelin sheath.
Axon Terminal: Endpoint of the axon where neurotransmitters are released.
Nerve impulse travels along the axon of the presynaptic neuron.
Calcium ions (Ca2+) enter through voltage-gated channels.
Synaptic vesicles release neurotransmitters into the synaptic cleft.
Neurotransmitters bind to receptors on the postsynaptic neuron.
This opens sodium channels, generating a postsynaptic potential.
Nerve impulse is propagated in postsynaptic neuron.
Reference: Freed, DB (2018).
Discusses motor speech disorders regarding the functioning of the neuromuscular junction.
Endoneurium: Encloses individual axons.
Perineurium: Bundles axons into fascicles.
Epineurium: Surrounds the entire nerve.
Classification by function: Sensory/Afferent and Motor/Efferent nerves.
Components:
The Brain
The Spinal Cord
Central Sulcus: Major landmark separating brain lobes.
Cerebral Cortex: Surface layer of the cerebrum.
Choroid Plexus: Produces cerebrospinal fluid.
Thalamus: Relay station for sensory impulses.
Meninges: Protective coverings of the brain and spinal cord.
Dura Mater: Tough outer layer.
Arachnoid Mater: Middle web-like layer.
Pia Mater: Delicate inner layer hugging the brain.
Frontal Lobe: Involved in decision-making and motor functions.
Parietal Lobe: Processes sensory information.
Temporal Lobe: Associated with memory and auditory processing.
Occipital Lobe: Responsible for vision.
Primary Motor Area: Controls voluntary movements.
Somatosensory Area: Processes sensory inputs.
Wernicke's Area: Involved in language comprehension.
Broca's Area: Governs speech production.
Brainstem: Controls basic life functions (Midbrain, Pons, Medulla Oblongata).
Cerebellum: Coordinates movement and balance.
General structures of the brain and references for surgical care literature.
Ends at L1-L2 vertebrae.
Contains nerve roots and meninges structure during thoracic and lumbar levels.
Dorsal Horn: Receives sensory input.
Ventral Horn: Contains motor neurons.
Gray Matter: Contains neuron cell bodies.
White Matter: Composed of myelinated axons.
Focus on functions and structure of the PNS.
Includes 12 paired cranial nerves, responsible for fundamental sensory and motor functions, including special senses and vital functions.
31 paired spinal nerves classification (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal).
A plexus is a network of nerves.
Includes cervical, brachial, lumbar, sacral, and coccygeal plexuses (except thoracic).
Cranial nerves serve exclusive motor or sensory roles in different combinations.
Sensory (Afferent): Convey sensory information to CNS.
Motor (Efferent): Transmit motor commands from CNS.
Autonomic Nervous System: Divided into sympathetic, parasympathetic, and enteric systems.
Overview of the physiological functions of the nervous system.
Detailed overview of vital functions performed by the CNS.
Specific areas of the brain associated with particular functions.
Discusses implications of damage to Broca's area in language production.
Comparison of functions between Broca's area (speech production) and Wernicke's area (language comprehension).
Discusses implications of damage to Wernicke's area affecting comprehension.
Overview of the left and right brain hemispheres and their specialized functions.
Research and publications relating to language recovery post-stroke.
Review of specific brain areas associated with distinct functionalities.
Importance of lateralization in understanding brain function, with a warning against oversimplification.
Overview of the basal ganglia and associated nuclei.
Midbrain, Pons and their respective roles.
Comparative anatomy of the cerebellum across species.
Overview of pathways where nerve fibers decussate (cross over).
Description of the corticospinal tract and its significance in motor function.
Analysis of spinal cord anatomy including dorsal and ventral horns, gray and white matter.
Summary of functions of the PNS.
Overview of somatic and autonomic systems in PNS.
Involves conscious sensations and voluntary muscle movements.
Differentiates between sympathetic and parasympathetic systems.
Overview of various autonomic functions.
Insights into major nerve plexuses within the body.
Mention of specific nerves and their functions.
Overview of nerves derived from the cervical plexus and their roles.
Citation: Freed (2018), discussing motor speech disorders.
Importance of sensory innervation in surgical procedures.
Overview of cranial nerve functions including special senses and motor functions.
Discussion of upper and lower motor neuron lesions affecting facial nerve outcomes.
Overview of concepts concerning pain response.
International Association for the Study of Pain: Defines pain as an unpleasant sensory and emotional experience.
Key points on personal experience, learning pain, and pain reporting.
Classification by region, duration, intensity, and causation.
Acute Pain: Short-term, resolves with the underlying condition.
Chronic Pain: Long-lasting pain affecting quality of life.
Pain types include dull, burning, or sharp sensations.
Defines nociceptors and their roles in pain detection from damaged tissue.
Thermal, Mechanical, Chemical, Silent, Polymodal: Types based on stimuli response.
Overview of action potential generation in nociceptors.
Overview of pathways involved in transmitting pain signals to the brain.
Mechanism describing how sharp pain signals are transmitted to the brain.
Describes pathways involved in transmitting dull, burning pain signals.
Terms associated with pain perception and modulation in the nervous system.
Gate Control Theory: Mechanism explaining how pain perception is modulated at various levels.
Relevance in general medical procedures related to cardiac function.
Discusses stress response, including functions of the sympathetic nervous system and neuroendocrine response.
Pause for refreshment and thought.
Discusses common clinical presentations.
Group discussion to review real-life examples of pain conditions.
Overview of a specific case related to nervous system health.
Re-evaluation of expected learning outcomes for the session.
Open floor for student questions and clarifications.
End of session summary and information about the next class.
Nicholas de Mora-Mieszkowski
The Nervous System
AHP 401 Introduction to Life Sciences
Identify anatomical structures and components of the nervous system.
Describe physiological functions and mechanisms of the nervous system.
Explain physiology associated with the sensation of pain.
Discuss pathophysiological changes due to common illnesses, diseases, injuries, and conditions of the nervous system.
Recap anatomy from pre-session activities.
Discuss physiological functions.
Examine physiology of pain.
Address muddiest points.
Review pathophysiological functional changes in common conditions/illnesses/injuries/diseases.
Cells and Tissues:
Neurones: Basic units of the nervous system conducting impulses.
Neuroglia: Supporting cells that provide insulation and support to neurons.
Central Nervous System (CNS):
Brain
Spinal Cord
Meninges & Cerebrospinal Fluid
Peripheral Nervous System (PNS):
Spinal nerves
Thoracic nerves
Cranial nerves
Autonomic nervous system
Neurones: Specialized cells conducting nerve impulses. Comprising a cell body, axon, and dendrites.
Neuroglia: Group of supporting cells that insulate and support neurons.
Dendrite: Receives signals from other neurons.
Nucleus: Control center of the cell.
Axon: Transmits impulses away from the neuron.
Cell Body: Contains the nucleus and organelles.
Myelin Sheath: Insulating layer around the axon.
Schwann's Cell: Cell forming the myelin sheath in the PNS.
Node of Ranvier: Gaps in the myelin sheath.
Axon Terminal: Endpoint of the axon where neurotransmitters are released.
Nerve impulse travels along the axon of the presynaptic neuron.
Calcium ions (Ca2+) enter through voltage-gated channels.
Synaptic vesicles release neurotransmitters into the synaptic cleft.
Neurotransmitters bind to receptors on the postsynaptic neuron.
This opens sodium channels, generating a postsynaptic potential.
Nerve impulse is propagated in postsynaptic neuron.
Reference: Freed, DB (2018).
Discusses motor speech disorders regarding the functioning of the neuromuscular junction.
Endoneurium: Encloses individual axons.
Perineurium: Bundles axons into fascicles.
Epineurium: Surrounds the entire nerve.
Classification by function: Sensory/Afferent and Motor/Efferent nerves.
Components:
The Brain
The Spinal Cord
Central Sulcus: Major landmark separating brain lobes.
Cerebral Cortex: Surface layer of the cerebrum.
Choroid Plexus: Produces cerebrospinal fluid.
Thalamus: Relay station for sensory impulses.
Meninges: Protective coverings of the brain and spinal cord.
Dura Mater: Tough outer layer.
Arachnoid Mater: Middle web-like layer.
Pia Mater: Delicate inner layer hugging the brain.
Frontal Lobe: Involved in decision-making and motor functions.
Parietal Lobe: Processes sensory information.
Temporal Lobe: Associated with memory and auditory processing.
Occipital Lobe: Responsible for vision.
Primary Motor Area: Controls voluntary movements.
Somatosensory Area: Processes sensory inputs.
Wernicke's Area: Involved in language comprehension.
Broca's Area: Governs speech production.
Brainstem: Controls basic life functions (Midbrain, Pons, Medulla Oblongata).
Cerebellum: Coordinates movement and balance.
General structures of the brain and references for surgical care literature.
Ends at L1-L2 vertebrae.
Contains nerve roots and meninges structure during thoracic and lumbar levels.
Dorsal Horn: Receives sensory input.
Ventral Horn: Contains motor neurons.
Gray Matter: Contains neuron cell bodies.
White Matter: Composed of myelinated axons.
Focus on functions and structure of the PNS.
Includes 12 paired cranial nerves, responsible for fundamental sensory and motor functions, including special senses and vital functions.
31 paired spinal nerves classification (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal).
A plexus is a network of nerves.
Includes cervical, brachial, lumbar, sacral, and coccygeal plexuses (except thoracic).
Cranial nerves serve exclusive motor or sensory roles in different combinations.
Sensory (Afferent): Convey sensory information to CNS.
Motor (Efferent): Transmit motor commands from CNS.
Autonomic Nervous System: Divided into sympathetic, parasympathetic, and enteric systems.
Overview of the physiological functions of the nervous system.
Detailed overview of vital functions performed by the CNS.
Specific areas of the brain associated with particular functions.
Discusses implications of damage to Broca's area in language production.
Comparison of functions between Broca's area (speech production) and Wernicke's area (language comprehension).
Discusses implications of damage to Wernicke's area affecting comprehension.
Overview of the left and right brain hemispheres and their specialized functions.
Research and publications relating to language recovery post-stroke.
Review of specific brain areas associated with distinct functionalities.
Importance of lateralization in understanding brain function, with a warning against oversimplification.
Overview of the basal ganglia and associated nuclei.
Midbrain, Pons and their respective roles.
Comparative anatomy of the cerebellum across species.
Overview of pathways where nerve fibers decussate (cross over).
Description of the corticospinal tract and its significance in motor function.
Analysis of spinal cord anatomy including dorsal and ventral horns, gray and white matter.
Summary of functions of the PNS.
Overview of somatic and autonomic systems in PNS.
Involves conscious sensations and voluntary muscle movements.
Differentiates between sympathetic and parasympathetic systems.
Overview of various autonomic functions.
Insights into major nerve plexuses within the body.
Mention of specific nerves and their functions.
Overview of nerves derived from the cervical plexus and their roles.
Citation: Freed (2018), discussing motor speech disorders.
Importance of sensory innervation in surgical procedures.
Overview of cranial nerve functions including special senses and motor functions.
Discussion of upper and lower motor neuron lesions affecting facial nerve outcomes.
Overview of concepts concerning pain response.
International Association for the Study of Pain: Defines pain as an unpleasant sensory and emotional experience.
Key points on personal experience, learning pain, and pain reporting.
Classification by region, duration, intensity, and causation.
Acute Pain: Short-term, resolves with the underlying condition.
Chronic Pain: Long-lasting pain affecting quality of life.
Pain types include dull, burning, or sharp sensations.
Defines nociceptors and their roles in pain detection from damaged tissue.
Thermal, Mechanical, Chemical, Silent, Polymodal: Types based on stimuli response.
Overview of action potential generation in nociceptors.
Overview of pathways involved in transmitting pain signals to the brain.
Mechanism describing how sharp pain signals are transmitted to the brain.
Describes pathways involved in transmitting dull, burning pain signals.
Terms associated with pain perception and modulation in the nervous system.
Gate Control Theory: Mechanism explaining how pain perception is modulated at various levels.
Relevance in general medical procedures related to cardiac function.
Discusses stress response, including functions of the sympathetic nervous system and neuroendocrine response.
Pause for refreshment and thought.
Discusses common clinical presentations.
Group discussion to review real-life examples of pain conditions.
Overview of a specific case related to nervous system health.
Re-evaluation of expected learning outcomes for the session.
Open floor for student questions and clarifications.
End of session summary and information about the next class.