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nervous system 2425 for moodle pre session

Page 1: Title Slide

  • Nicholas de Mora-Mieszkowski

  • The Nervous System

  • AHP 401 Introduction to Life Sciences

Page 2: Learning Outcomes

  • Identify anatomical structures and components of the nervous system.

  • Describe physiological functions and mechanisms of the nervous system.

  • Explain physiology associated with the sensation of pain.

  • Discuss pathophysiological changes due to common illnesses, diseases, injuries, and conditions of the nervous system.

Page 3: Session Overview

  • Recap anatomy from pre-session activities.

  • Discuss physiological functions.

  • Examine physiology of pain.

  • Address muddiest points.

  • Review pathophysiological functional changes in common conditions/illnesses/injuries/diseases.

Page 4: Structures of the Nervous System

  • Cells and Tissues:

    • Neurones: Basic units of the nervous system conducting impulses.

    • Neuroglia: Supporting cells that provide insulation and support to neurons.

  • Central Nervous System (CNS):

    • Brain

    • Spinal Cord

    • Meninges & Cerebrospinal Fluid

  • Peripheral Nervous System (PNS):

    • Spinal nerves

    • Thoracic nerves

    • Cranial nerves

    • Autonomic nervous system

Page 5: Nervous Tissue

  • Neurones: Specialized cells conducting nerve impulses. Comprising a cell body, axon, and dendrites.

  • Neuroglia: Group of supporting cells that insulate and support neurons.

Page 6: Neuronal Structure

  • Dendrite: Receives signals from other neurons.

  • Nucleus: Control center of the cell.

  • Axon: Transmits impulses away from the neuron.

  • Cell Body: Contains the nucleus and organelles.

  • Myelin Sheath: Insulating layer around the axon.

  • Schwann's Cell: Cell forming the myelin sheath in the PNS.

  • Node of Ranvier: Gaps in the myelin sheath.

  • Axon Terminal: Endpoint of the axon where neurotransmitters are released.

Page 7: Synaptic Transmission

  1. Nerve impulse travels along the axon of the presynaptic neuron.

  2. Calcium ions (Ca2+) enter through voltage-gated channels.

  3. Synaptic vesicles release neurotransmitters into the synaptic cleft.

  4. Neurotransmitters bind to receptors on the postsynaptic neuron.

  5. This opens sodium channels, generating a postsynaptic potential.

  6. Nerve impulse is propagated in postsynaptic neuron.

Page 8: Neuromuscular Junction

  • Reference: Freed, DB (2018).

  • Discusses motor speech disorders regarding the functioning of the neuromuscular junction.

Page 9: Nerves and Connective Tissue

  • Endoneurium: Encloses individual axons.

  • Perineurium: Bundles axons into fascicles.

  • Epineurium: Surrounds the entire nerve.

  • Classification by function: Sensory/Afferent and Motor/Efferent nerves.

Page 10: Central Nervous System Overview

  • Components:

    • The Brain

    • The Spinal Cord

Page 11: Parts of the Central Nervous System

  • Central Sulcus: Major landmark separating brain lobes.

  • Cerebral Cortex: Surface layer of the cerebrum.

  • Choroid Plexus: Produces cerebrospinal fluid.

  • Thalamus: Relay station for sensory impulses.

  • Meninges: Protective coverings of the brain and spinal cord.

Page 12: Meninges Anatomy

  • Dura Mater: Tough outer layer.

  • Arachnoid Mater: Middle web-like layer.

  • Pia Mater: Delicate inner layer hugging the brain.

Page 13: Brain Lobes

  • Frontal Lobe: Involved in decision-making and motor functions.

  • Parietal Lobe: Processes sensory information.

  • Temporal Lobe: Associated with memory and auditory processing.

  • Occipital Lobe: Responsible for vision.

Page 14: Brain Structures

  • Primary Motor Area: Controls voluntary movements.

  • Somatosensory Area: Processes sensory inputs.

  • Wernicke's Area: Involved in language comprehension.

  • Broca's Area: Governs speech production.

Page 15: Brainstem and Cerebellum

  • Brainstem: Controls basic life functions (Midbrain, Pons, Medulla Oblongata).

  • Cerebellum: Coordinates movement and balance.

Page 16: Brain References

  • General structures of the brain and references for surgical care literature.

Page 17: Spinal Cord Structure

  • Ends at L1-L2 vertebrae.

  • Contains nerve roots and meninges structure during thoracic and lumbar levels.

Page 18: Spinal Cord Anatomy

  • Dorsal Horn: Receives sensory input.

  • Ventral Horn: Contains motor neurons.

  • Gray Matter: Contains neuron cell bodies.

  • White Matter: Composed of myelinated axons.

Page 19: Peripheral Nervous System Overview

  • Focus on functions and structure of the PNS.

Page 20: Cranial Nerves

  • Includes 12 paired cranial nerves, responsible for fundamental sensory and motor functions, including special senses and vital functions.

Page 21: Spinal Nerves

  • 31 paired spinal nerves classification (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal).

Page 22: Plexuses

  • A plexus is a network of nerves.

  • Includes cervical, brachial, lumbar, sacral, and coccygeal plexuses (except thoracic).

Page 23: Cranial Nerves Functionality

  • Cranial nerves serve exclusive motor or sensory roles in different combinations.

Page 24: Peripheral Nervous System Types

  • Sensory (Afferent): Convey sensory information to CNS.

  • Motor (Efferent): Transmit motor commands from CNS.

  • Autonomic Nervous System: Divided into sympathetic, parasympathetic, and enteric systems.

Page 25: Physiological Functions

  • Overview of the physiological functions of the nervous system.

Page 26: Central Nervous System Functions

  • Detailed overview of vital functions performed by the CNS.

Page 27: Brain Function Localization

  • Specific areas of the brain associated with particular functions.

Page 28: Broca's Type Aphasia

  • Discusses implications of damage to Broca's area in language production.

Page 29: Broca's vs. Wernicke's Area

  • Comparison of functions between Broca's area (speech production) and Wernicke's area (language comprehension).

Page 30: Wernicke's Type Aphasia

  • Discusses implications of damage to Wernicke's area affecting comprehension.

Page 31: Hemispheres and Lateralization

  • Overview of the left and right brain hemispheres and their specialized functions.

Page 32: Predicting Language Outcomes After Stroke

  • Research and publications relating to language recovery post-stroke.

Page 33: Localization of Brain Functions

  • Review of specific brain areas associated with distinct functionalities.

Page 34: Brain Lateralization

  • Importance of lateralization in understanding brain function, with a warning against oversimplification.

Page 35: Basal Ganglia Structures

  • Overview of the basal ganglia and associated nuclei.

Page 36: Brainstem Components

  • Midbrain, Pons and their respective roles.

Page 37: Cerebellum Variations

  • Comparative anatomy of the cerebellum across species.

Page 38: Commissures and Decussation

  • Overview of pathways where nerve fibers decussate (cross over).

Page 39: Pyramidal Tract Overview

  • Description of the corticospinal tract and its significance in motor function.

Page 40: Spinal Cord Structures

  • Analysis of spinal cord anatomy including dorsal and ventral horns, gray and white matter.

Page 41: Peripheral Nervous System Functions

  • Summary of functions of the PNS.

Page 42: Functional Organization

  • Overview of somatic and autonomic systems in PNS.

Page 43: Somatic Nervous System

  • Involves conscious sensations and voluntary muscle movements.

Page 44: Autonomic Nervous System

  • Differentiates between sympathetic and parasympathetic systems.

Page 45: Autonomic Functions Overview

  • Overview of various autonomic functions.

Page 46: Plexus Overview

  • Insights into major nerve plexuses within the body.

Page 47: Cervical Plexus Overview

  • Mention of specific nerves and their functions.

Page 48: Cervical Nerve Functions

  • Overview of nerves derived from the cervical plexus and their roles.

Page 49: Reference Materials

  • Citation: Freed (2018), discussing motor speech disorders.

Page 50: Sensory Innervation by Spinal Nerves

  • Importance of sensory innervation in surgical procedures.

Page 51: Cranial Nerves Functions

  • Overview of cranial nerve functions including special senses and motor functions.

Page 52: Hemispheric Contributions to Motor Control

  • Discussion of upper and lower motor neuron lesions affecting facial nerve outcomes.

Page 53: Introduction to Pain

  • Overview of concepts concerning pain response.

Page 54: Definition of Pain

  • International Association for the Study of Pain: Defines pain as an unpleasant sensory and emotional experience.

  • Key points on personal experience, learning pain, and pain reporting.

Page 55: Pain Classification System

  • Classification by region, duration, intensity, and causation.

Page 56: Pain Duration Classification

  • Acute Pain: Short-term, resolves with the underlying condition.

  • Chronic Pain: Long-lasting pain affecting quality of life.

Page 57: Pain Characteristics

  • Pain types include dull, burning, or sharp sensations.

Page 58: Nociception Overview

  • Defines nociceptors and their roles in pain detection from damaged tissue.

Page 59: Types of Nociceptors and Functions

  • Thermal, Mechanical, Chemical, Silent, Polymodal: Types based on stimuli response.

Page 60: Action Potential in Neurons

  • Overview of action potential generation in nociceptors.

Page 61: Pain Pathway

  • Overview of pathways involved in transmitting pain signals to the brain.

Page 62: Sharp Pain Process

  • Mechanism describing how sharp pain signals are transmitted to the brain.

Page 63: Dull Pain Process

  • Describes pathways involved in transmitting dull, burning pain signals.

Page 64: Key Pain Terms

  • Terms associated with pain perception and modulation in the nervous system.

Page 65: Pain Perception Theories

  • Gate Control Theory: Mechanism explaining how pain perception is modulated at various levels.

Page 66: Defibrillator and Referred Pain

  • Relevance in general medical procedures related to cardiac function.

Page 67: Integration in the Body

  • Discusses stress response, including functions of the sympathetic nervous system and neuroendocrine response.

Page 68: Break

  • Pause for refreshment and thought.

Page 69: Common Issues in Pain and Functional Disorders

  • Discusses common clinical presentations.

Page 70: Activity

  • Group discussion to review real-life examples of pain conditions.

Page 71: Example Case Study

  • Overview of a specific case related to nervous system health.

Page 72: Revisiting Learning Outcomes

  • Re-evaluation of expected learning outcomes for the session.

Page 73: Questions

  • Open floor for student questions and clarifications.

Page 74: Conclusion

  • End of session summary and information about the next class.

EW

nervous system 2425 for moodle pre session

Page 1: Title Slide

  • Nicholas de Mora-Mieszkowski

  • The Nervous System

  • AHP 401 Introduction to Life Sciences

Page 2: Learning Outcomes

  • Identify anatomical structures and components of the nervous system.

  • Describe physiological functions and mechanisms of the nervous system.

  • Explain physiology associated with the sensation of pain.

  • Discuss pathophysiological changes due to common illnesses, diseases, injuries, and conditions of the nervous system.

Page 3: Session Overview

  • Recap anatomy from pre-session activities.

  • Discuss physiological functions.

  • Examine physiology of pain.

  • Address muddiest points.

  • Review pathophysiological functional changes in common conditions/illnesses/injuries/diseases.

Page 4: Structures of the Nervous System

  • Cells and Tissues:

    • Neurones: Basic units of the nervous system conducting impulses.

    • Neuroglia: Supporting cells that provide insulation and support to neurons.

  • Central Nervous System (CNS):

    • Brain

    • Spinal Cord

    • Meninges & Cerebrospinal Fluid

  • Peripheral Nervous System (PNS):

    • Spinal nerves

    • Thoracic nerves

    • Cranial nerves

    • Autonomic nervous system

Page 5: Nervous Tissue

  • Neurones: Specialized cells conducting nerve impulses. Comprising a cell body, axon, and dendrites.

  • Neuroglia: Group of supporting cells that insulate and support neurons.

Page 6: Neuronal Structure

  • Dendrite: Receives signals from other neurons.

  • Nucleus: Control center of the cell.

  • Axon: Transmits impulses away from the neuron.

  • Cell Body: Contains the nucleus and organelles.

  • Myelin Sheath: Insulating layer around the axon.

  • Schwann's Cell: Cell forming the myelin sheath in the PNS.

  • Node of Ranvier: Gaps in the myelin sheath.

  • Axon Terminal: Endpoint of the axon where neurotransmitters are released.

Page 7: Synaptic Transmission

  1. Nerve impulse travels along the axon of the presynaptic neuron.

  2. Calcium ions (Ca2+) enter through voltage-gated channels.

  3. Synaptic vesicles release neurotransmitters into the synaptic cleft.

  4. Neurotransmitters bind to receptors on the postsynaptic neuron.

  5. This opens sodium channels, generating a postsynaptic potential.

  6. Nerve impulse is propagated in postsynaptic neuron.

Page 8: Neuromuscular Junction

  • Reference: Freed, DB (2018).

  • Discusses motor speech disorders regarding the functioning of the neuromuscular junction.

Page 9: Nerves and Connective Tissue

  • Endoneurium: Encloses individual axons.

  • Perineurium: Bundles axons into fascicles.

  • Epineurium: Surrounds the entire nerve.

  • Classification by function: Sensory/Afferent and Motor/Efferent nerves.

Page 10: Central Nervous System Overview

  • Components:

    • The Brain

    • The Spinal Cord

Page 11: Parts of the Central Nervous System

  • Central Sulcus: Major landmark separating brain lobes.

  • Cerebral Cortex: Surface layer of the cerebrum.

  • Choroid Plexus: Produces cerebrospinal fluid.

  • Thalamus: Relay station for sensory impulses.

  • Meninges: Protective coverings of the brain and spinal cord.

Page 12: Meninges Anatomy

  • Dura Mater: Tough outer layer.

  • Arachnoid Mater: Middle web-like layer.

  • Pia Mater: Delicate inner layer hugging the brain.

Page 13: Brain Lobes

  • Frontal Lobe: Involved in decision-making and motor functions.

  • Parietal Lobe: Processes sensory information.

  • Temporal Lobe: Associated with memory and auditory processing.

  • Occipital Lobe: Responsible for vision.

Page 14: Brain Structures

  • Primary Motor Area: Controls voluntary movements.

  • Somatosensory Area: Processes sensory inputs.

  • Wernicke's Area: Involved in language comprehension.

  • Broca's Area: Governs speech production.

Page 15: Brainstem and Cerebellum

  • Brainstem: Controls basic life functions (Midbrain, Pons, Medulla Oblongata).

  • Cerebellum: Coordinates movement and balance.

Page 16: Brain References

  • General structures of the brain and references for surgical care literature.

Page 17: Spinal Cord Structure

  • Ends at L1-L2 vertebrae.

  • Contains nerve roots and meninges structure during thoracic and lumbar levels.

Page 18: Spinal Cord Anatomy

  • Dorsal Horn: Receives sensory input.

  • Ventral Horn: Contains motor neurons.

  • Gray Matter: Contains neuron cell bodies.

  • White Matter: Composed of myelinated axons.

Page 19: Peripheral Nervous System Overview

  • Focus on functions and structure of the PNS.

Page 20: Cranial Nerves

  • Includes 12 paired cranial nerves, responsible for fundamental sensory and motor functions, including special senses and vital functions.

Page 21: Spinal Nerves

  • 31 paired spinal nerves classification (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal).

Page 22: Plexuses

  • A plexus is a network of nerves.

  • Includes cervical, brachial, lumbar, sacral, and coccygeal plexuses (except thoracic).

Page 23: Cranial Nerves Functionality

  • Cranial nerves serve exclusive motor or sensory roles in different combinations.

Page 24: Peripheral Nervous System Types

  • Sensory (Afferent): Convey sensory information to CNS.

  • Motor (Efferent): Transmit motor commands from CNS.

  • Autonomic Nervous System: Divided into sympathetic, parasympathetic, and enteric systems.

Page 25: Physiological Functions

  • Overview of the physiological functions of the nervous system.

Page 26: Central Nervous System Functions

  • Detailed overview of vital functions performed by the CNS.

Page 27: Brain Function Localization

  • Specific areas of the brain associated with particular functions.

Page 28: Broca's Type Aphasia

  • Discusses implications of damage to Broca's area in language production.

Page 29: Broca's vs. Wernicke's Area

  • Comparison of functions between Broca's area (speech production) and Wernicke's area (language comprehension).

Page 30: Wernicke's Type Aphasia

  • Discusses implications of damage to Wernicke's area affecting comprehension.

Page 31: Hemispheres and Lateralization

  • Overview of the left and right brain hemispheres and their specialized functions.

Page 32: Predicting Language Outcomes After Stroke

  • Research and publications relating to language recovery post-stroke.

Page 33: Localization of Brain Functions

  • Review of specific brain areas associated with distinct functionalities.

Page 34: Brain Lateralization

  • Importance of lateralization in understanding brain function, with a warning against oversimplification.

Page 35: Basal Ganglia Structures

  • Overview of the basal ganglia and associated nuclei.

Page 36: Brainstem Components

  • Midbrain, Pons and their respective roles.

Page 37: Cerebellum Variations

  • Comparative anatomy of the cerebellum across species.

Page 38: Commissures and Decussation

  • Overview of pathways where nerve fibers decussate (cross over).

Page 39: Pyramidal Tract Overview

  • Description of the corticospinal tract and its significance in motor function.

Page 40: Spinal Cord Structures

  • Analysis of spinal cord anatomy including dorsal and ventral horns, gray and white matter.

Page 41: Peripheral Nervous System Functions

  • Summary of functions of the PNS.

Page 42: Functional Organization

  • Overview of somatic and autonomic systems in PNS.

Page 43: Somatic Nervous System

  • Involves conscious sensations and voluntary muscle movements.

Page 44: Autonomic Nervous System

  • Differentiates between sympathetic and parasympathetic systems.

Page 45: Autonomic Functions Overview

  • Overview of various autonomic functions.

Page 46: Plexus Overview

  • Insights into major nerve plexuses within the body.

Page 47: Cervical Plexus Overview

  • Mention of specific nerves and their functions.

Page 48: Cervical Nerve Functions

  • Overview of nerves derived from the cervical plexus and their roles.

Page 49: Reference Materials

  • Citation: Freed (2018), discussing motor speech disorders.

Page 50: Sensory Innervation by Spinal Nerves

  • Importance of sensory innervation in surgical procedures.

Page 51: Cranial Nerves Functions

  • Overview of cranial nerve functions including special senses and motor functions.

Page 52: Hemispheric Contributions to Motor Control

  • Discussion of upper and lower motor neuron lesions affecting facial nerve outcomes.

Page 53: Introduction to Pain

  • Overview of concepts concerning pain response.

Page 54: Definition of Pain

  • International Association for the Study of Pain: Defines pain as an unpleasant sensory and emotional experience.

  • Key points on personal experience, learning pain, and pain reporting.

Page 55: Pain Classification System

  • Classification by region, duration, intensity, and causation.

Page 56: Pain Duration Classification

  • Acute Pain: Short-term, resolves with the underlying condition.

  • Chronic Pain: Long-lasting pain affecting quality of life.

Page 57: Pain Characteristics

  • Pain types include dull, burning, or sharp sensations.

Page 58: Nociception Overview

  • Defines nociceptors and their roles in pain detection from damaged tissue.

Page 59: Types of Nociceptors and Functions

  • Thermal, Mechanical, Chemical, Silent, Polymodal: Types based on stimuli response.

Page 60: Action Potential in Neurons

  • Overview of action potential generation in nociceptors.

Page 61: Pain Pathway

  • Overview of pathways involved in transmitting pain signals to the brain.

Page 62: Sharp Pain Process

  • Mechanism describing how sharp pain signals are transmitted to the brain.

Page 63: Dull Pain Process

  • Describes pathways involved in transmitting dull, burning pain signals.

Page 64: Key Pain Terms

  • Terms associated with pain perception and modulation in the nervous system.

Page 65: Pain Perception Theories

  • Gate Control Theory: Mechanism explaining how pain perception is modulated at various levels.

Page 66: Defibrillator and Referred Pain

  • Relevance in general medical procedures related to cardiac function.

Page 67: Integration in the Body

  • Discusses stress response, including functions of the sympathetic nervous system and neuroendocrine response.

Page 68: Break

  • Pause for refreshment and thought.

Page 69: Common Issues in Pain and Functional Disorders

  • Discusses common clinical presentations.

Page 70: Activity

  • Group discussion to review real-life examples of pain conditions.

Page 71: Example Case Study

  • Overview of a specific case related to nervous system health.

Page 72: Revisiting Learning Outcomes

  • Re-evaluation of expected learning outcomes for the session.

Page 73: Questions

  • Open floor for student questions and clarifications.

Page 74: Conclusion

  • End of session summary and information about the next class.

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