Bio Chapter 5

Chapter 5 Test Study Guide

The Working Cell


This is a brief overview of the topics we covered in Chapter Five, not a comprehensive guide for the Test. You should review this as well as your notes, worksheets, labs, review games, etc.


Big Ideas: 

  1. A cell membrane’s structure enables its many functions, such as regulating traffic across the membrane. 

  2. A cell’s metabolic reactions transform energy, using ATP to drive cellular work. 

  3. Enzymes speed up a cell’s chemical reactions and provide precise control of metabolism. 


5.1 Membranes are fluid mosaics of lipids and proteins with many functions

  • What is the Fluid mosaic model? 

    • Why is the plasma membrane called that?

    • What does selective permeability mean?

    • What are the types of proteins/molecules found within the plasma membrane 

      • Transport proteins - allows specific ions or molecules to enter and leave the cell

      • Enzymes - grouped to carry out sequential chemical reactions, only the reactant and the substrate can go through

      • Attachment Proteins - attached to the extracellular matrix and cytoskeleton, helps to support the membrane, coordinates external and internal changes

      • Receptor Proteins - signal molecules bind to receptor proteins, relay information by activating other molecules in the cell

      • Junction Proteins - form junctions between two cells to attach them

      • Glycoproteins - act as an ID tag, could be recognized by other membrane proteins on other cells

        • Image pg 87


5.3 Passive transport is diffusion across a membrane with no energy investment

  • Define passive transport.

    • What is diffusion?

      • Know word problems

  • What is a concentration gradient?

    • What direction do molecules move?


5.4 Osmosis is the diffusion of water across a membrane

  • Define osmosis

    • How does water move in relation to other solutes?

      • Know word problems

    • What is the transport protein that allows water to pass through?


5.5 Water balance between cells and their surroundings is crucial to organisms

  • What is tonicity?  

    • Know the difference between isotonic, hypertonic, and hypotonic

    • What examples of each

    • Be familiar with what happens to cells that are placed in those solutions

      • Image pg 81


5.6 Transport proteins can facilitate diffusion across membranes

  • What is facilitated diffusion?

  • How is it different from diffusion?

    • Know word problems


5.8 Cells expand energy in the active transport of a solute 

  • What is active transport?

  • Be familiar with the Na/K pump mechanisms 


5.9 Exocytosis and endocytosis transport large molecules across membranes 

  • What is exocytosis? What is endocytosis?

    • Compare and contrast

    • Know examples of each


5.10 Cells transform energy and matter as they perform work

  • What are the different forms of energy?

  • How is energy transformed?

    • Know the 1st law of thermodynamics

      • Image pg 84


5.11 Chemical reactions either release or store energy 

  • What are exergonic and endergonic reactions?

    • How do they use energy?

    • Know examples of each


5.12 ATP drives cellular work by coupling exergonic and endergonic reactions 

  • What is ATP?

    • Know the chemical structure 

    • Compare and contrast ADP and ATP

  • How do we use ATP?

    • Know examples of different cellular work powered by ATP


5.13 Enzymes speed up the cells’ chemical reaction by lowering energy barriers 

  • What is a catalyst?

  • What is an enzyme?

    • How do they do the work? 



5.14 A specific enzyme catalyzes each reaction

  • What is the catalytic cycle of an enzyme?

    • How is the shape of an enzyme related to its function?

  • What are the optimal conditions for enzymes?


5.15 Enzymes inhibition can regulate enzyme activity in a cell

  • Compare and contrast competitive, noncompetitive and feedback inhibition


5.16 Many drugs, pesticides and poisons are enzyme inhibitors

  • Know some examples 


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