Overview of reconstituting injections using powdered medications for injection
Importance of understanding different types of syringes, parenteral dosages, vials, and ampoules
Focus on prednisone prescriptions commonly encountered in pharmacy settings
Importance of calculating the correct dosage: formula = Desired / Have x Quantity
Applicable to various forms of medication: solids, oral solids, oral liquids, and injections
Accuracy in calculations is critical to patient safety; wrong drug or dosage can have serious consequences
Solutions are easier to withdraw; powders are used for longer shelf life and stability
Powder must be reconstituted properly to ensure safety and efficacy
Understanding drug concentrations: 2% means 2 grams in 100 milliliters
Different ways to express strengths: milligrams per milliliter, units (i.e., insulin)
Example: Insulin dosing expressed in units, e.g., "Inject twenty units before meals"
Single-dose vials are designed for one-time use only
Multi-dose vials can be used multiple times; left overs can be stored according to instructions
Importance of knowing how many doses are required per prescription
Parenteral administration: not via the gastrointestinal tract (subcutaneous, intramuscular, intravenous)
Understanding the Greek origins of the term ‘parenteral’
Critical areas of the syringe that must not be touched to avoid contamination
Proper handling techniques for syringes, particularly in a sterile environment
Different syringes based on dosage; standard 3ml for 1ml or more, tuberculin syringes for less than 1ml
Needles vary in gauge; smaller gauge number indicates thicker needle
Importance of selecting correct needle length and gauge based on injection type
Prefilled syringes ready to use but require careful patient instruction
Safety syringes designed to minimize needle-stick injuries
Specialized for insulin, calibrated in units; must only use insulin syringes for insulin administration
Used for very small doses; calibrated in hundreds of a milliliter
Precise measurements, requiring attention to detail for liquid doses less than one milliliter
Always convert percent concentrations or ratios to indicate dosage strength in milliliters
Two decimal places must be used for doses less than one milliliter
Example: 0.5ml tuberculin syringe for 0.6ml doses
Instructions for reconstituting powdered injections safely
Ensuring no visible particles before administration
Importance of proper storage and refrigeration practices
Mastery of these concepts is essential for pharmacy technicians to ensure safe and effective patient care.