Science – Systematic study of the natural world based on observation and experimentation.
Biology – The study of living organisms and their interactions with the environment.
Importance of Biology – Helps us understand life processes, medicine, environmental conservation, and evolution.
Characteristics of Life – Organization, metabolism, homeostasis, growth, reproduction, response to stimuli, evolution.
Hierarchical Organization of Life – Atoms → Molecules → Cells → Tissues → Organs → Organ Systems → Organisms → Populations → Communities → Ecosystems → Biosphere.
Scientific Discovery Process – Observation, hypothesis formation, experimentation, analysis, conclusion.
Hypothesis vs. Theory – A hypothesis is a testable explanation; a theory is a well-supported, broad explanation of phenomena.
Variables in an Experiment – Independent (manipulated), dependent (measured), controlled (constant).
Four Themes in Biology – Evolution, structure-function relationships, information flow, energy transformation, interconnections.
Chapter 2: Chemistry of Life
Atom Structure – Nucleus (protons, neutrons), electrons in orbitals.
Subatomic Particles – Protons (positive), neutrons (neutral), electrons (negative).
Atomic Number vs. Atomic Mass – Atomic number = protons; Atomic mass = protons + neutrons.
Atoms vs. Isotopes – Isotopes have different numbers of neutrons but the same number of protons.
Importance of Isotopes – Used in medicine (radioactive tracers), dating fossils.
Energy Levels & Electrons – Electrons exist in shells; higher shells have more energy.
Octet Rule – Atoms tend to gain, lose, or share electrons to complete an octet.
Ions vs. Atoms – Ions have gained/lost electrons, making them charged.
Chemical Identity – Determined by the number of protons.
Oxidation & Reduction – Oxidation = loss of electrons; reduction = gain of electrons.
Bond Formation – Elements combine based on valence electrons.
Types of Bonds – Covalent (strong), ionic (transfer electrons), hydrogen (weak attractions).
Electronegativity – An atom’s ability to attract electrons.
Water’s Role in Biology – Universal solvent, high heat capacity, cohesion/adhesion.
Water Ionization – H₂O → H⁺ + OH⁻.
Acids vs. Bases – Acids donate H⁺, bases accept H⁺.
pH Scale – Measures acidity/alkalinity; biological systems maintain homeostasis.
Buffers – Maintain stable pH in biological systems.
Chapter 3: Macromolecules
Carbon Chemistry – Carbon forms diverse organic molecules.
Four Macromolecules – Carbohydrates, lipids, proteins, nucleic acids.
Elements in Macromolecules – C, H, O, N, P, S.
Functional Groups – Hydroxyl, carboxyl, amino, phosphate.
Monomers & Polymers – Monomers link to form polymers via dehydration synthesis.
Dehydration vs. Hydrolysis – Dehydration builds molecules; hydrolysis breaks them down.
Carbohydrates – Monosaccharides (glucose), disaccharides (sucrose), polysaccharides (starch).
Isomers – Same formula, different structure (glucose vs. fructose).
Cellulose & Chitin – Structural polysaccharides.
DNA vs. RNA – DNA = double helix, RNA = single-stranded.
Amino Acid Structure – Amino group, carboxyl group, R group.
Protein Structure – Primary, secondary, tertiary, quaternary.
Saturated vs. Unsaturated Fats – Saturated = no double bonds, solid; unsaturated = double bonds, liquid.
Lipid Functions – Energy storage, membrane structure, signaling.
Chapter 4: Cell Structure & Function
Cell Size Limitation – Surface area-to-volume ratio constraints.
Plasma Membrane – Composed of phospholipids, proteins, cholesterol.
Cell Theory – All living things are made of cells; cells arise from preexisting cells.
Prokaryotes vs. Eukaryotes – Prokaryotes lack nuclei; eukaryotes have membrane-bound organelles.
Cell Organelles & Functions – Nucleus (DNA storage), mitochondria (ATP production), ribosomes (protein synthesis).
Rough vs. Smooth ER – Rough ER has ribosomes; smooth ER synthesizes lipids.
Lysosomes vs. Peroxisomes – Lysosomes digest; peroxisomes detoxify.
Cytoskeleton Components – Microfilaments, intermediate filaments, microtubules.
Mitochondria & Chloroplasts – Energy-producing organelles.
Endosymbiotic Theory – Mitochondria and chloroplasts originated from bacteria.
Animal vs. Plant Cells – Plants have cell walls, chloroplasts, central vacuoles.
Extracellular Matrix – Provides structural support in animal cells.
Chapter 5: Membranes & Transport
Phospholipid Bilayer – Hydrophilic heads, hydrophobic tails.
Membrane Components – Phospholipids, proteins, cholesterol, carbohydrates.
Fluid Mosaic Model – Describes dynamic nature of membranes.
Membrane Proteins – Transport, enzymes, receptors, recognition, adhesion, cytoskeleton attachment.
Passive vs. Active Transport – Passive = no energy; active = ATP required.
Diffusion & Osmosis – Movement of molecules and water.
Tonicity – Hypertonic (water leaves), hypotonic (water enters), isotonic (equilibrium).
Endocytosis & Exocytosis – Transport mechanisms for large molecules.
Selective Permeability – Only specific molecules cross membranes freely.