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Digestive System Vocabulary Review

Overview of the Digestive System

  • Lecture Objectives:
    • General features of the digestive system from oral cavity to large intestine and accessory organs.
    • Chemical and mechanical digestion sites across the gut tube.
    • Understanding the enteric nervous system.
    • Description of peritoneum folds.

Anatomy of the Digestive System

  • Key Components:
    • Oral Cavity:
    • Contains teeth and tongue.
    • Involved in ingestion and initial mechanical digestion.
    • Salivary Glands:
    • Parotid, Submandibular, Sublingual Glands
    • Produce saliva to aid in digestion.
    • Esophagus:
    • Transports food from mouth to stomach.
    • Stomach:
    • J-shaped organ for mixing and digesting food.
    • Small Intestine:
    • Comprises the duodenum, jejunum, and ileum.
    • Primary site for chemical digestion and nutrient absorption.
    • Large Intestine:
    • Absorbs water, electrolytes; compacts waste.
    • Contains cecum, colon, rectum, and anus.

Digestion Fundamentals

  • Types of Digestion:
    • Chemical Digestion: Breakdown of food by enzymes (e.g., saliva, gastric juice).
    • Mechanical Digestion: Physical breakdown of food (e.g., chewing, churning in stomach).

The Alimentary Canal

  • A continuous tube from mouth to anus, modified into sections:
    • Ingestion
    • Mechanical Processing
    • Transport
    • Secretion
    • Chemical Changes
    • Absorption
    • Defecation

Layers of the Gut Tube

  1. Mucosa: Innermost layer; contains epithelium, lamina propria.
  2. Submucosa: Connective tissue layer with blood vessels, nerves.
  3. Muscularis: Responsible for peristalsis (circular and longitudinal muscle layers).
  4. Serosa: Outermost layer; visceral peritoneum.

Peritoneum

  • Layers:
    • Parietal Peritoneum: Lines abdominal cavity.
    • Visceral Peritoneum: Covers abdominal organs.
    • Mesentery: Folds of the peritoneum that support organs, containing blood vessels and nerves.

The Digestive Tract

Mouth

  • Structure:
    • Bounded by cheeks, palate, lips; contains vestibule and fauces.

Salivary Glands

  • Functions of Saliva:
    • Hydrolyzes starch with salivary amylase.
    • Provides lubrication for swallowing.
    • Antimicrobial activity via lysozyme.

Teeth

  • Types of Teeth:
    • Incisors: Biting.
    • Canines: Tearing.
    • Molars: Grinding.
  • Components: Enamel, dentine, cementum.

Deglutition (Swallowing)

  1. Voluntary Phase: Bolus pushed to oropharynx; triggers swallowing reflex.
  2. Involuntary Phase: Peristalsis moves food through the esophagus.

Stomach

  • Function:
    • Mixes bolus with gastric juices to form chyme.
    • Chemical Digestion: Pepsin or gastric lipase.
    • Mechanical Digestion: Waves of muscle contraction.

Small Intestine

  • Sections: Duodenum, jejunum, ileum.
  • Functions:
    • Chemical digestion via intestinal juices and enzyme activity.
    • Enhances absorption through villi and microvilli.

Pancreas

  • Functions:
    • Endocrine: Hormone secretion (insulin, glucagon).
    • Exocrine: Produces digestive enzymes (e.g., amylase, lipase).

Liver and Gallbladder

  • Liver Functions:
    • Produces bile for fat emulsification.
  • Gallbladder: Stores bile until needed for digestion.

Large Intestine

  • Mechanism: Peristalsis and haustral churning.
  • Functions:
    • Absorption of water and electrolytes.
    • Formation of feces.
  • Bacterial Fermentation: Conversion of nutrients and production of vitamins.

Defecation

  • Reflex actions leading to expulsion of feces, driven by the gastrocolic reflex and activation of sacral nerves.

Control of Digestive Processes

  • Enteric Nervous System:
    • Regulates digestive activities via sensory and motor neurons.
    • Influenced by autonomic nervous system (ANS).

Digestive Enzymes Summary

  • Salivary: Salivary amylase, lingual lipase.
  • Gastric: Pepsin, gastric lipase.
  • Pancreatic: Amylase, lipase, trypsin, chemotrypsin, nucleases.
  • Intestinal: Peptidase, intestinal lipase, sucrose.

Absorption of Water

  • Approximately 9 liters of fluid secreted into the GI tract daily, with 8 liters reabsorbed by the small intestine.