Exchange Reaction: Example with Sodium Chloride and Hydrochloric Acid.
Sodium hydroxide + Hydrochloric acid → Sodium chloride + Water.
Synthesis Reaction: Formation of a Triglyceride from ATP and Fatty Acids.
ATP + Fatty Acids → Triglyceride + Water (water is lost).
Understanding organic vs. inorganic molecules:
Inorganic molecules: Smaller, lack carbon, simple structure.
Examples: Water, salts, acids, bases.
Organic molecules: Larger, contain carbon, more complex.
Examples: Carbohydrates, proteins, nucleic acids.
Water: Most abundant molecule in the body (60-70% of body weight).
High heat capacity: Requires a lot of energy to change temperatures; important for maintaining body temperature (homeostasis).
Ability to dissolve substances: Dissolves salts (Na+ and Cl− ions), critical for muscle contraction, nerve signal transmission, and blood clotting.
Water participation in chemical reactions:
Hydrolysis: Breakdown of larger molecules using water.
Dehydration Synthesis: Formation of larger molecules while releasing water.
Importance in aging: Hydration for joint lubrication and cushioning.
Salts: Formed from reaction of an acid with a base.
Break apart into ions (charged atoms/electrolytes).
Acids and Bases:
Acids: Release hydrogen ions (H+) in water; strength depends on H+ concentration.
Bases: Release hydroxide ions (OH−) in water.
pH Scale: Ranges from 0 to 14; 7 is neutral (e.g., water); blood around 7.4; stomach acid around 1-2; definitions of hyperglycemia and hypoglycemia.
Importance of maintaining pH levels across different body systems; buffers help manage pH.
Carbohydrates: Composed of carbon, hydrogen, and oxygen (C, H, O); ratio is typically 2:1 for H:O.
Groups of carbohydrates:
Monosaccharides: Single sugar units (e.g., glucose, fructose).
Disaccharides: Two monosaccharides (e.g., sucrose from glucose + fructose).
Polysaccharides: Long chains of monosaccharides (e.g., glycogen, starch).
Energy Storage:
Glucose stored as glycogen in liver/muscles and utilized during energy-intensive activities (e.g., exercise).
Structure vs. Function: The shape of molecules influences their roles and functionalities in the body (anatomy and physiology principles).
Structural comparison: Different structures can lead to different biochemical functions, even with the same molecular formula (e.g., glucose vs. fructose vs. galactose, all C6H12O6).
Breakdown of carbohydrates during digestion:
Hydrolysis of starches yields glucose.
Re-synthesis of glucose into glycogen for storage (energy reserves).
The course will cover the role of various molecules (organic and inorganic) in human physiology and biochemistry, linked to digestion, homeostasis, and energy production.