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Sensation, Perception, and Cranial Nerves

Sensation and Perception

  • Sensation: The process where environmental or internal stimuli are converted into electrochemical signals (action potentials).
  • Perception: The processing and interpretation of these signals within the central nervous system (CNS), leading to conscious awareness of the stimulus.

Sensory Receptors

  • Sensory receptors convert stimuli into action potentials.
  • Categorized by location:
    • General Receptors: Spread throughout the body tissues.
      • Examples: Touch/pressure, heat, pain.
    • Special Receptors: Located in specific organs.
      • Examples: Sight, smell, hearing, taste.

Categories of Receptors Based on Stimulus Type

  • Chemoreceptors: Detect the presence and/or concentration of chemicals.
  • Pain Receptors (Nociceptors): Detect tissue damage.
  • Thermoreceptors: Detect changes in temperature.
  • Mechanoreceptors: Detect changes in pressure or movement.
  • Photoreceptors: Detect changes in light energy.

Categories of Receptors Based on Structure

  • Free Nerve Endings:
    • Dendrites of neurons that act as receptors.
  • Encapsulated Nerve Endings:
    • Nerve endings enclosed in a connective tissue capsule.
  • Specialized Receptor Cells:
    • Cells with distinct structures, like rods in the eye.

Sensory Processing Pathway

  • The general sensory processing pathway is as follows:
    • Peripheral sensation → Nerve pathway → CNS → Spinal cord or brainstem → Thalamus → Primary sensory cortex → Association areas

Touch and Related Senses

  • Touch/Pressure Receptors:
    • Free Nerve Endings: Detect general touch and pressure.
    • Meissner’s Corpuscles (Tactile Corpuscles): Detect light touch and low-frequency vibrations, especially in the skin of fingertips and lips.
    • Pacinian Corpuscles (Lamellated Corpuscles): Detect deep pressure and high-frequency vibrations.

Pain Receptors

  • Pain Receptors:
    • Free Nerve Endings: Detect tissue damage.
    • Transmembrane receptors:
      • Bind to chemicals released when tissue is damaged.
      • Triggered by extremes in temperature, pressure/movement and chemicals.

Thermoreceptors

  • Thermoreceptors:
    • Free Nerve Endings: Detect temperatures different from body temperature.
      • Different receptors for hot and cold.

Sensory Processing Pathway (Repeated)

  • The general sensory processing pathway is as follows:
    • Peripheral sensation → Nerve pathway → CNS → Spinal cord or brainstem → Thalamus → Primary sensory cortex → Association areas

Cranial Nerves

The following is a summary table of the 12 cranial nerves:

#NameFunction(S/M/B)Central Connection (Nuclei)Peripheral Connection (Ganglion or Muscle)
IOlfactorySmell(S)Olfactory bulbOlfactory epithelium
IIOpticVision(S)Hypothalamus/thalamus/midbrainRetina (retinal ganglion cells)
IIIOculomotorEye movements(M)Oculomotor nucleusExtraocular muscles (other 4), levator palpebrae superioris, ciliary ganglion (autonomic)
IVTrochlearEye movements(M)Trochlear nucleusSuperior oblique muscle
VTrigeminalSensory/motor - face(B)Trigeminal nuclei in the midbrain, pons, and medullaTrigeminal
VIAbducensEye movements(M)Abducens nucleusLateral rectus muscle
VIIFacialMotor- face, Taste(B)Facial nucleus, solitary nucleus, superior salivatory nucleusFacial muscles, Geniculate ganglion, Pterygopalatine ganglion (autonomic)
VIIIVestibulocochlearHearing/ balance(S)Cochlear nucleus, Vestibular nucleus/cerebellumSpiral ganglion (hearing), Vestibular ganglion (balance)
IXGlossopharyngealMotor - throat, Taste(B)Solitary nucleus, inferior salivatory nucleus, nucleus ambiguusPharyngeal muscles, Geniculate ganglion, Otic ganglion (autonomic)
XISpinal AccessoryMotor - head and neck(M)Spinal accessory nucleusNeck muscles
XVagusMotor/sensory- viscera (autonomic)(B)MedullaTerminal ganglia serving thoracic and upper abdominal organs (heart and small intestines)
XIIHypoglossalMotor - lower throat(M)Hypoglossal nucleusMuscles of the larynx and lower pharynx

Brain Lobe Diagram.

  • Frontal Lobe
    • Includes the precentral gyrus (area 4), which is the primary motor cortex, and Broca's area (areas 44, 45).
  • Parietal Lobe
    • Contains the postcentral gyrus (areas 1, 2, 3), which is the primary somatosensory cortex, the angular gyrus (area 39), and the supramarginal gyrus (area 40).
  • Occipital Lobe
    • Located at the back.
  • Temporal Lobe
    • Features the primary auditory cortex (area 22).
  • Other Structures
    • Includes the midbrain, pons, medulla, hypothalamus, pituitary gland, and thalamus.