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HLTA0H3 FINAL EXAM PT 2

Paradigms of Health Research week 9


Research Paradigm: reflects one's belief about what constitutes knowledge and how knowledge should be generated 


Three Dimensions: Epistemology, Ontology, Methodology 


Epistemology - concerned with nature and definition of knowledge and truth, define types of data considered “valid” or “useful”


Two parts of Epistemology: Positivism, Interpretivism

Positivism 

  • scientific processes based on observation and measurement

Ex. cause and effect, clinical trials for new drugs, assess causation, measurable outcomes 

  • Ex. Measuring population health through epidemiological studies 


Interpretivism 

  • Generates subjective understandings, not measurement but meaning, more description wise   

Ex. understanding patient experience with chronic illness, lived experience of the disease, personal meanings and themes 





Ontology - Branch of philosophy focused on nature of reality, things that have a fixed reality is independent of our perspectives 


Two parts: Objectivism, Constructionism 

Objectivism

  • External reality exists independently of observation 

Ex. a tumour exists whether or not a patient/ doctor recognise it 


Constructionism 

  • Socially constructed objects

  • Reality is socially constructed 

Ex. depression is not a biological reality but shaped by social understandings 


Methodology - data collection and analysis 


Two parts: Quantitative, Qualitative 

Quantitative 

  • Relies on numeric data and analysis

  • Guided by measurement 

Ex. surveys

Qualitative

  • Relies on open ended questions, with meaning and experience

Ex. focus groups, interviews



Research Question

What physiological and neurological factors influence pain intensity

How do individuals with chronic pain make sense of their experience?

Epistemology

Positivism: pain is measurable, objective

Interpretivism: experience of pain is subjective and shaped by the individual / social context 

Ontology

Objectivism: pain exists independently of human perception

Constructivism: pain is socially constructed experience is shaped by language and culture 

Methodology

Quantitative: numerical data, experiments, statistical analyses

Qualitative: narratives, personal stories, thematic analysis


Patient satisfaction with telehealth services using interviews to understand barriers to access

  • Positivism 

  • Interpretivism 

Obesity as a biological condition caused by genetics and metabolism

  • Objectivism 

  • Constructivism

Mental health treatment effectiveness as measured by symptom

  • Quantitative 

  • Qualitative 


Health Research Methodologies part 1 week 10


Quantitative Methods?

  • Study designs: driven by study question, available population for study, and current state of research 


Quantitative study designs: Randomised control trial, Cohort, Case- Control, Cross-sectional study


Randomised Control Trial - evaluate the therapeutic effects of disease in a person

  • researcher controls who receives the treatment or exposure and who gets the alternative

  • Control group: those receiving alternative


Cohort Study - people with diseases are sampled and classified according to whether they have the exposure or not 

  • Followed overtime to see who gets the disease

  • Health measurements and incidence rates


Case-control study - cases from specific populations are studied 

  • Matching: cases and controls from similar populations..age, sex, race/ ethnicity, SES


Cross-sectional / prevalence study - population sampled and disease status measured at the same time 

  • can’t predict causality, incidence rates cannot be calculated

Ecological studies 

  • Not individual level data, data summarizing exposure and disease samples or populations 


Statistics - Study of the use of statistical principles that allows us to understand data 


Data - Numbers that represent some features of something you're measuring 


Measurement - Process of assigning numbers to a thing


Types of Measurement: Nominal, Ordinal, Interval 

Nominal: number represents a label for a category


Ordinal: category of things can be ordered(smaller, larger, before or after)


Interval: Category of things can be put in groups equally spaced


Categorical judgments

  • People choose among a number of alternatives


Scaling judgments 

  • Continuous judgments: requires person to indicate their response along a continuum

  • Likert scale: extreme values at both ends

Confidence interval 

  • Gives range of values within which we expect the true population parameter to fall

Ex. 95% confident that the true effect is between 1.5 and 2.5 = 95% CL of (1.5, 2.5)


P-value 

  • How likely we are to observe data if the null hypothesis were true 


Health Research methodologies part 2 week 11


 Qualitative research?

  • Attempts to find out what's going on, what is happening, and the nature of something from the perspective of those involved in the study

Naturalistic: research in natural environment, rather then lab


Interpretive: constructing meaning from data sith the aim of explaining the phenomenon 

Explores: identification of health needs, patterns in health seeking behaviors 


Approaches to Qualitative Research: Ethnography, Autoethnography, Phenomenology, Grounded Theory, Qualitative Description 


Ethnography: 

  • Oldest approach, focus on exploration of culture 

  • Roots in anthropology 

  • Specific places, people


Autoethnography:

  • links personal to cultural through self-narrative 

  • Focus on the individual, researcher becomes participant and observer


Phenomenology: 

  • Seeks to explore, and analyse “lived experience” 

  • Gain deeper understanding of nature of everyday experiences

  • Identifies object of human experience (pain)


Grounded Theory: 

  • Develop theory based on data 

Qualitative Description:

  • Research that doesn’t fit neatly into other types 

  • Against forcing research into a type 


Sampling: 

purposeful sampling:

selecting best participants based on quality of their insights

 

snowball sampling: 

participants are asked to invite others who meet sampling criteria


convenience sampling:

selected based on availability 


theoretical sampling:

based on emerging theoretical framework 


Methods 

Visual methods - photo voice

  • collaboration with community partners is central focus 

Focus groups 

  • involves more then two participants in a focused interview

Interviews 

  • guided conversation 


Rigour : 

keeping an audit trail  - documenting research decisions and rationale 


reflexivity - examining one’s place, biography, self and others to understand how they shape analytic exercise 


prolonged engagement - extended time in field


Member engagement - exploring findings with participants 

triangulation - check integrity of inferences using multiple data 


peer debriefing - checking findings and interpretation with a peer



Ethical Consideration Week 12


Ethics

  • branch of philosophy associated with the systematic examination of right and wrong 

Ethical challenges 

  • Conflicts over treatment decisions

  • Determining essential services 

  • All of services for vulnerable populations 

  • Shortage of healthcare worker to provide care

  • Decisions about end of life care 

  • Determining who can make health care decisions on behalf of another 

  • Medical error emergence of new technologies 

  • Ability to give informed consent prior to receiving care

  • Risks and benefits of participation in medical research 


Ethics in healthcare practice: 

  • determining essential services 

  • lack of services for vulnerable populations 

  • shortage of healthcare workers to provide care 



4. Potential conflicts : 

conflict of interest - will research team members, or immediate family members receive any personal benefit 


restrictions on information - are there any restrictions regarding access, or disclosing of information 


Researcher relationships - are there any pre-existing relationships between the researcher and researched? 


Collaborative decision making - is this a community based project?