Paradigms of Health Research week 9
Research Paradigm: reflects one's belief about what constitutes knowledge and how knowledge should be generatedÂ
Three Dimensions: Epistemology, Ontology, MethodologyÂ
Epistemology - concerned with nature and definition of knowledge and truth, define types of data considered “valid” or “useful”
Two parts of Epistemology: Positivism, Interpretivism
PositivismÂ
scientific processes based on observation and measurement
Ex. cause and effect, clinical trials for new drugs, assess causation, measurable outcomesÂ
Ex. Measuring population health through epidemiological studiesÂ
InterpretivismÂ
Generates subjective understandings, not measurement but meaning, more description wise  Â
Ex. understanding patient experience with chronic illness, lived experience of the disease, personal meanings and themesÂ
Ontology - Branch of philosophy focused on nature of reality, things that have a fixed reality is independent of our perspectivesÂ
Two parts: Objectivism, ConstructionismÂ
Objectivism
External reality exists independently of observationÂ
Ex. a tumour exists whether or not a patient/ doctor recognise itÂ
ConstructionismÂ
Socially constructed objects
Reality is socially constructedÂ
Ex. depression is not a biological reality but shaped by social understandingsÂ
Methodology - data collection and analysisÂ
Two parts: Quantitative, QualitativeÂ
QuantitativeÂ
Relies on numeric data and analysis
Guided by measurementÂ
Ex. surveys
Qualitative
Relies on open ended questions, with meaning and experience
Ex. focus groups, interviews
Research Question | What physiological and neurological factors influence pain intensity | How do individuals with chronic pain make sense of their experience? |
Epistemology | Positivism: pain is measurable, objective | Interpretivism: experience of pain is subjective and shaped by the individual / social context |
Ontology | Objectivism: pain exists independently of human perception | Constructivism: pain is socially constructed experience is shaped by language and culture |
Methodology | Quantitative: numerical data, experiments, statistical analyses | Qualitative: narratives, personal stories, thematic analysis |
Patient satisfaction with telehealth services using interviews to understand barriers to access
PositivismÂ
InterpretivismÂ
Obesity as a biological condition caused by genetics and metabolism
ObjectivismÂ
Constructivism
Mental health treatment effectiveness as measured by symptom
QuantitativeÂ
QualitativeÂ
Health Research Methodologies part 1 week 10
Quantitative Methods?
Study designs: driven by study question, available population for study, and current state of researchÂ
Quantitative study designs: Randomised control trial, Cohort, Case- Control, Cross-sectional study
Randomised Control Trial - evaluate the therapeutic effects of disease in a person
researcher controls who receives the treatment or exposure and who gets the alternative
Control group: those receiving alternative
Cohort Study - people with diseases are sampled and classified according to whether they have the exposure or notÂ
Followed overtime to see who gets the disease
Health measurements and incidence rates
Case-control study - cases from specific populations are studiedÂ
Matching: cases and controls from similar populations..age, sex, race/ ethnicity, SES
Cross-sectional / prevalence study - population sampled and disease status measured at the same timeÂ
can’t predict causality, incidence rates cannot be calculated
Ecological studiesÂ
Not individual level data, data summarizing exposure and disease samples or populationsÂ
Statistics - Study of the use of statistical principles that allows us to understand dataÂ
Data - Numbers that represent some features of something you're measuringÂ
Measurement - Process of assigning numbers to a thing
Types of Measurement: Nominal, Ordinal, IntervalÂ
Nominal: number represents a label for a category
Ordinal: category of things can be ordered(smaller, larger, before or after)
Interval: Category of things can be put in groups equally spaced
Categorical judgments
People choose among a number of alternatives
Scaling judgmentsÂ
Continuous judgments: requires person to indicate their response along a continuum
Likert scale: extreme values at both ends
Confidence intervalÂ
Gives range of values within which we expect the true population parameter to fall
Ex. 95% confident that the true effect is between 1.5 and 2.5 = 95% CL of (1.5, 2.5)
P-valueÂ
How likely we are to observe data if the null hypothesis were trueÂ
Health Research methodologies part 2 week 11
 Qualitative research?
Attempts to find out what's going on, what is happening, and the nature of something from the perspective of those involved in the study
Naturalistic: research in natural environment, rather then lab
Interpretive: constructing meaning from data sith the aim of explaining the phenomenonÂ
Explores: identification of health needs, patterns in health seeking behaviorsÂ
Approaches to Qualitative Research: Ethnography, Autoethnography, Phenomenology, Grounded Theory, Qualitative DescriptionÂ
Ethnography:Â
Oldest approach, focus on exploration of cultureÂ
Roots in anthropologyÂ
Specific places, people
Autoethnography:
links personal to cultural through self-narrativeÂ
Focus on the individual, researcher becomes participant and observer
Phenomenology:Â
Seeks to explore, and analyse “lived experience”Â
Gain deeper understanding of nature of everyday experiences
Identifies object of human experience (pain)
Grounded Theory:Â
Develop theory based on dataÂ
Qualitative Description:
Research that doesn’t fit neatly into other typesÂ
Against forcing research into a typeÂ
Sampling:Â
purposeful sampling:
selecting best participants based on quality of their insights
Â
snowball sampling:Â
participants are asked to invite others who meet sampling criteria
convenience sampling:
selected based on availabilityÂ
theoretical sampling:
based on emerging theoretical frameworkÂ
MethodsÂ
Visual methods - photo voice
collaboration with community partners is central focusÂ
Focus groupsÂ
involves more then two participants in a focused interview
InterviewsÂ
guided conversationÂ
Rigour :Â
keeping an audit trail  - documenting research decisions and rationaleÂ
reflexivity - examining one’s place, biography, self and others to understand how they shape analytic exerciseÂ
prolonged engagement - extended time in field
Member engagement - exploring findings with participantsÂ
triangulation - check integrity of inferences using multiple dataÂ
peer debriefing - checking findings and interpretation with a peer
Ethical Consideration Week 12
Ethics :Â
branch of philosophy associated with the systematic examination of right and wrongÂ
Ethical challengesÂ
Conflicts over treatment decisions
Determining essential servicesÂ
All of services for vulnerable populationsÂ
Shortage of healthcare worker to provide care
Decisions about end of life careÂ
Determining who can make health care decisions on behalf of anotherÂ
Medical error emergence of new technologiesÂ
Ability to give informed consent prior to receiving care
Risks and benefits of participation in medical researchÂ
Ethics in healthcare practice:Â
determining essential servicesÂ
lack of services for vulnerable populationsÂ
shortage of healthcare workers to provide careÂ
4. Potential conflicts :Â
conflict of interest - will research team members, or immediate family members receive any personal benefitÂ
restrictions on information - are there any restrictions regarding access, or disclosing of informationÂ
Researcher relationships - are there any pre-existing relationships between the researcher and researched?Â
Collaborative decision making - is this a community based project?