Paradigms of Health Research week 9
Research Paradigm: reflects one's belief about what constitutes knowledge and how knowledge should be generated
Three Dimensions: Epistemology, Ontology, Methodology
Epistemology - concerned with nature and definition of knowledge and truth, define types of data considered “valid” or “useful”
Two parts of Epistemology: Positivism, Interpretivism
Positivism
scientific processes based on observation and measurement
Ex. cause and effect, clinical trials for new drugs, assess causation, measurable outcomes
Ex. Measuring population health through epidemiological studies
Interpretivism
Generates subjective understandings, not measurement but meaning, more description wise
Ex. understanding patient experience with chronic illness, lived experience of the disease, personal meanings and themes
Ontology - Branch of philosophy focused on nature of reality, things that have a fixed reality is independent of our perspectives
Two parts: Objectivism, Constructionism
Objectivism
External reality exists independently of observation
Ex. a tumour exists whether or not a patient/ doctor recognise it
Constructionism
Socially constructed objects
Reality is socially constructed
Ex. depression is not a biological reality but shaped by social understandings
Methodology - data collection and analysis
Two parts: Quantitative, Qualitative
Quantitative
Relies on numeric data and analysis
Guided by measurement
Ex. surveys
Qualitative
Relies on open ended questions, with meaning and experience
Ex. focus groups, interviews
Research Question | What physiological and neurological factors influence pain intensity | How do individuals with chronic pain make sense of their experience? |
Epistemology | Positivism: pain is measurable, objective | Interpretivism: experience of pain is subjective and shaped by the individual / social context |
Ontology | Objectivism: pain exists independently of human perception | Constructivism: pain is socially constructed experience is shaped by language and culture |
Methodology | Quantitative: numerical data, experiments, statistical analyses | Qualitative: narratives, personal stories, thematic analysis |
Patient satisfaction with telehealth services using interviews to understand barriers to access
Positivism
Interpretivism
Obesity as a biological condition caused by genetics and metabolism
Objectivism
Constructivism
Mental health treatment effectiveness as measured by symptom
Quantitative
Qualitative
Health Research Methodologies part 1 week 10
Quantitative Methods?
Study designs: driven by study question, available population for study, and current state of research
Quantitative study designs: Randomised control trial, Cohort, Case- Control, Cross-sectional study
Randomised Control Trial - evaluate the therapeutic effects of disease in a person
researcher controls who receives the treatment or exposure and who gets the alternative
Control group: those receiving alternative
Cohort Study - people with diseases are sampled and classified according to whether they have the exposure or not
Followed overtime to see who gets the disease
Health measurements and incidence rates
Case-control study - cases from specific populations are studied
Matching: cases and controls from similar populations..age, sex, race/ ethnicity, SES
Cross-sectional / prevalence study - population sampled and disease status measured at the same time
can’t predict causality, incidence rates cannot be calculated
Ecological studies
Not individual level data, data summarizing exposure and disease samples or populations
Statistics - Study of the use of statistical principles that allows us to understand data
Data - Numbers that represent some features of something you're measuring
Measurement - Process of assigning numbers to a thing
Types of Measurement: Nominal, Ordinal, Interval
Nominal: number represents a label for a category
Ordinal: category of things can be ordered(smaller, larger, before or after)
Interval: Category of things can be put in groups equally spaced
Categorical judgments
People choose among a number of alternatives
Scaling judgments
Continuous judgments: requires person to indicate their response along a continuum
Likert scale: extreme values at both ends
Confidence interval
Gives range of values within which we expect the true population parameter to fall
Ex. 95% confident that the true effect is between 1.5 and 2.5 = 95% CL of (1.5, 2.5)
P-value
How likely we are to observe data if the null hypothesis were true
Health Research methodologies part 2 week 11
Qualitative research?
Attempts to find out what's going on, what is happening, and the nature of something from the perspective of those involved in the study
Naturalistic: research in natural environment, rather then lab
Interpretive: constructing meaning from data sith the aim of explaining the phenomenon
Explores: identification of health needs, patterns in health seeking behaviors
Approaches to Qualitative Research: Ethnography, Autoethnography, Phenomenology, Grounded Theory, Qualitative Description
Ethnography:
Oldest approach, focus on exploration of culture
Roots in anthropology
Specific places, people
Autoethnography:
links personal to cultural through self-narrative
Focus on the individual, researcher becomes participant and observer
Phenomenology:
Seeks to explore, and analyse “lived experience”
Gain deeper understanding of nature of everyday experiences
Identifies object of human experience (pain)
Grounded Theory:
Develop theory based on data
Qualitative Description:
Research that doesn’t fit neatly into other types
Against forcing research into a type
Sampling:
purposeful sampling:
selecting best participants based on quality of their insights
snowball sampling:
participants are asked to invite others who meet sampling criteria
convenience sampling:
selected based on availability
theoretical sampling:
based on emerging theoretical framework
Methods
Visual methods - photo voice
collaboration with community partners is central focus
Focus groups
involves more then two participants in a focused interview
Interviews
guided conversation
Rigour :
keeping an audit trail - documenting research decisions and rationale
reflexivity - examining one’s place, biography, self and others to understand how they shape analytic exercise
prolonged engagement - extended time in field
Member engagement - exploring findings with participants
triangulation - check integrity of inferences using multiple data
peer debriefing - checking findings and interpretation with a peer
Ethical Consideration Week 12
Ethics :
branch of philosophy associated with the systematic examination of right and wrong
Ethical challenges
Conflicts over treatment decisions
Determining essential services
All of services for vulnerable populations
Shortage of healthcare worker to provide care
Decisions about end of life care
Determining who can make health care decisions on behalf of another
Medical error emergence of new technologies
Ability to give informed consent prior to receiving care
Risks and benefits of participation in medical research
Ethics in healthcare practice:
determining essential services
lack of services for vulnerable populations
shortage of healthcare workers to provide care
4. Potential conflicts :
conflict of interest - will research team members, or immediate family members receive any personal benefit
restrictions on information - are there any restrictions regarding access, or disclosing of information
Researcher relationships - are there any pre-existing relationships between the researcher and researched?
Collaborative decision making - is this a community based project?