Terms to know:
Glycolipid- any membrane lipid that is bound to a carbohydrate
Cholesterol- type of lipid found in the blood plays a role in building cell membrane and produces hormones
facilitated diffusion- the facilitated transport of ions and polar molecules through a membrane via protein complexes
Hypotonic- the property of a solution that has a lower solute concentrations then another solution
Isotonic- same
Hypertonic- the property of a solution that has a high solute concentration than another solution
Uniport- move 1 molecule in 1 direction, also known as a primary active transport, ex ca
Symport- protein moves 2 different molecules in the same direction
Antiport- protein moves 2 different molecules in 2 different directions
Integral protein- a protein that is embedded in the lipid bilayer
peripheral protein- a protein that on the surface of the membrane
Endocytosis- proteins and large molecules are brought into the cell, membrane folds inward forming pseudopodia “false feet” eventually they fuse forming a vesicle trapping the molecules, import into cell
Exocytosis- vesicles move through cell and fuse will cell membrane, vesicles opens and releases molecules to exterior of cell, used for hormones, proteins that need to get into bloodstream, export out of the cell
Pinocytosis- “cell drinking” cell brings in water and dissolved solutes
Phagocytosis- “cell eating” cell bring in solid molecules (dead cell virus) used by immune system
Be able to label the diagram of the cell membrane.
What are the functions of the cell membrane? (7)
Transport material into cells (glucose, minerals, o2)
Transport products and wastes out of (ATP, protein, Co2)
Prevent entry of unwanted matter (toxic)
Cell recognition- “name tags” recognize cells as self or foreign
Site of reaction- light absorption, ATP synthesis
Communication- between cells, uses hormones, nerve impulses and receptors
Physical connections- connects cell together or to tissue
What is the structure of a phospholipid? How does this account for the formation of the lipid bilayer?
2 fatty acid tails linked to a glycerol backbone with a phosphate group
Tails are hydrophobic (non-polar)
Heads are hydrophilic (polar)
What is the function of sterols in the membrane?
Sterols- act as a membrane stabilizes
influence membrane fluidity
ex cholesterol
What is the function of integral and peripheral proteins?
Integral- span the entire membrane
Peripheral- stuck on outside
What is the function of glycolipids and glycoproteins
carbs attached to lipids or protiens are embedded in the membrane and act as receptors or name tags to help identify the type of cell as well as provide a site for hormones
Compare and contrast passive to active transport. How does facilitated diffusion compare to each?
Passive transport | Active transport |
Movement of substances across a membrane from high concentrations to low concentrations | Solutes move from low concentrations to high concentrations |
No energy required | The cell must use energy (ATP) and a protein to do this |
moves smaller molecules | moves larger molecules |
The larger the gradient the faster the rate | Uniport known as primary active transport |
2 type diffusion and facilitated diffusion | endocytosis and exocytosis |
Facilitated diffusion
Movement from high to low concentrations
Small non-polar molecules (o2, co2)
Small polar uncharged molecules (glycerol, water) can move through the membrane
NO ions, large molecules or charged molecules
What type of molecules will pass by passive? By active?
Small Nonpolar Molecules – (e.g., oxygen, carbon dioxide)
Small Polar Molecules – (e.g., water, ethanol)
Ions (with channels) – (e.g., Na⁺, K⁺ through ion channels)
Large Molecules – (e.g., glucose, amino acids)
Ions – (e.g., Na⁺, K⁺ against concentration gradient)
Macromolecules – (e.g., proteins, polysaccharides)
9.Use a diagram to explain what happens when a cell is in hypertonic, hypotonic and isotonic conditions.
Hypotonic
More solute (NA+) in the cell
Water moves into the dilute (balance)
Concentrations
Animal cells- Lyse “burst”
Plant cells- turgid
Hypertonic
More solutes outside of cell
Water moves out to balance
Animal cells- shrivel
Plant cells- wilt
Isotonic
When the solute concentration
Inside and outside the cell is balanced
Water continues to move in and out
At the equal rate
10. Explain specifically how temperature changes, pH changes and organic solvents work to destroy the cell membrane.
Unsaturated- have kinks or bends which make membrane more fluid
Colder temp- molecules pack together closely and make it more viscous “gel like”
More unsaturated- lower its gelling temp
High temp- help keep phospholipids together
11. uniport = moves 1 molecule in 1 direction (also known as primary active transport)
symport= protien moves 2 different molecules in the same direction
antiport= protien moves 2 different molecules in 2 different directions