Module 14: Amino Acids
Amino acids - are ter building blocks of proteins.
Amino acids - They belong to an important class of organic compounds that contain both the amino (-NH2) and carboxyl (-COOH) groups.
alpha – amino acids: what do you call the 20 most important amino acids?
the alpha – carbon atom: the amino and carboxyl groups are both attached to a single carbon atom, which is called?
D-(dextrorotatory) or L-(levorotatory): Amino acids may either be?
D-serine: present in the forebrain
D-aspartate: present both in brain and periphery
Amino acids: may have positive, negative or zero net charge.
ionic character: The solubility and melting points of amino acids reflect their?
polar solvents such as water and ethanol: Amino acids are soluble in
nonpolar such as benzene, hexane, or ether: Amino acids are insoluble in?
ALIPHATIC AMINO ACIDS – possess hydrocarbon side chains arranged in chain-like structures otherwise known as the monoamino – monocarboxylic acids
ALIPHATIC AMINO ACIDS: otherwise known as monoamino – monocarboxylic acids
AROMATIC AMINO ACIDS – possess the benzene ring (C6H6) in their side chains
HYDROXYAMINO ACIDS – possess the hydroxyl group (-OH) in their side chains
ACIDIC AMINO ACIDS – possess an additional carboxyl group (-COOH)
AMIDES OF ACIDIC AMINO ACIDS – possess an amide group (-CONH2) in their side chains
BASIC AMINO ACIDS – possess an additional amino group (-NH2) in their side chains
SULFUR-CONTAINING AMINO ACIDS – possess a thiol group (-SH) in their side chains
IMINO ACIDS – they have a cyclic imino group in their structure
NON – POLAR (HYDROPHOBIC) AMINO ACIDS - They prefer to contact with one another than water.
NON – POLAR (HYDROPHOBIC) AMINO ACIDS - Generally found buried in the interior of proteins, where they can associate with one another and remain isolated from water.
Polar, neutral amino acids: have R groups that have a high affinity for water but are not ionic.
Negatively charged amino acids: have ionized carboxyl group in their side chains. At pH 7, these amino acids have a net charge of -1
Positively charged amino acids: have a positive net charge of + 1 because their side chains contain a positive group
ESSENTIAL AMINO ACIDS – are those that cannot be synthesized by the body and are required in the diet.
NON – ESSENTIAL AMINO ACIDS – are those that can be synthesized by the body and need not be included in the
diet
Histidine: is an essential amino acid for infants but not for adults.
Cysteine and Tyrosine: are considered to be semi-essential amino acids.
Cysteine and Tyrosine: They are required by premature infants and adults who are ill.
Amino acids - are ter building blocks of proteins.
Amino acids - They belong to an important class of organic compounds that contain both the amino (-NH2) and carboxyl (-COOH) groups.
alpha – amino acids: what do you call the 20 most important amino acids?
the alpha – carbon atom: the amino and carboxyl groups are both attached to a single carbon atom, which is called?
D-(dextrorotatory) or L-(levorotatory): Amino acids may either be?
D-serine: present in the forebrain
D-aspartate: present both in brain and periphery
Amino acids: may have positive, negative or zero net charge.
ionic character: The solubility and melting points of amino acids reflect their?
polar solvents such as water and ethanol: Amino acids are soluble in
nonpolar such as benzene, hexane, or ether: Amino acids are insoluble in?
ALIPHATIC AMINO ACIDS – possess hydrocarbon side chains arranged in chain-like structures otherwise known as the monoamino – monocarboxylic acids
ALIPHATIC AMINO ACIDS: otherwise known as monoamino – monocarboxylic acids
AROMATIC AMINO ACIDS – possess the benzene ring (C6H6) in their side chains
HYDROXYAMINO ACIDS – possess the hydroxyl group (-OH) in their side chains
ACIDIC AMINO ACIDS – possess an additional carboxyl group (-COOH)
AMIDES OF ACIDIC AMINO ACIDS – possess an amide group (-CONH2) in their side chains
BASIC AMINO ACIDS – possess an additional amino group (-NH2) in their side chains
SULFUR-CONTAINING AMINO ACIDS – possess a thiol group (-SH) in their side chains
IMINO ACIDS – they have a cyclic imino group in their structure
NON – POLAR (HYDROPHOBIC) AMINO ACIDS - They prefer to contact with one another than water.
NON – POLAR (HYDROPHOBIC) AMINO ACIDS - Generally found buried in the interior of proteins, where they can associate with one another and remain isolated from water.
Polar, neutral amino acids: have R groups that have a high affinity for water but are not ionic.
Negatively charged amino acids: have ionized carboxyl group in their side chains. At pH 7, these amino acids have a net charge of -1
Positively charged amino acids: have a positive net charge of + 1 because their side chains contain a positive group
ESSENTIAL AMINO ACIDS – are those that cannot be synthesized by the body and are required in the diet.
NON – ESSENTIAL AMINO ACIDS – are those that can be synthesized by the body and need not be included in the
diet
Histidine: is an essential amino acid for infants but not for adults.
Cysteine and Tyrosine: are considered to be semi-essential amino acids.
Cysteine and Tyrosine: They are required by premature infants and adults who are ill.