fate of synthesized proteins

Fate of synthesized protein

The peptide obtained by the end of protein synthesis is not active and needs to undergo some

modifications in order to become active protein.

1. Indicate the importance of post-translation modifications.

The post-translation modifications make the synthesized peptide active.

2. Name the kinds of post-translation modifications?

- Combination of more than one peptide and folding them

- Decarboxylation: removal of carbon-dioxide

- Removal of certain peptides

- Addition of elements such as iron

- Addition of sugar or lipids

3. Name the site where post-translation modifications occur.

Rough endoplasmic reticulum (RER)

4. A concept map which summarizes the site of translation of functional and structural

proteins.

Ribosomes

Free Bound on rough endoplasmic reticulum

Produce functional

proteins that are

exported outside the

cell ex. Hormones,

enzymes, and

antibodies.

Produce structural

proteins that stay

inside the cell to

become part of

membrane or

structure of the

organelles or could

be a part of the cell

membrane

Produce structural

proteins that enter in the

structure of the cytoplasm

ex. Hb

There are 300 million Hb

evenly spread in RBC

2

5. Make a functional diagram showing the pathway of the synthesized functional protein

exported outside the cell.

Title: Functional diagram showing the pathway of the synthesized functional protein exported

outside the cell.

Ribosome RER golgi bodies secretory vesicle outside the cell by exocytosis

6. What is the role of golgi bodies?

Golgi bodies package proteins that are destined for export outside of the cell or to the cell

surface membrane. The proteins leave the golgi bodies packaged in secretory vesicles.

7. Define exocytosis.

Exocytosis: is the fusion of the membrane of the secretory vesicle with the cell membrane

to release the active synthesized protein outside the cell.

8. What is the role of mitochondria?

It is the power house of the cell that supplies the energy needed for the activity of the

cell.