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Pharmacology exam 1 review

Chapter 1: Basics of Drug Use & Abuse

Q: What is psychopharmacology?

A: The study of how drugs affect the brain, body, and behavior.

Q: Difference between drug use and drug abuse?

A:

  • Use = Taking a drug, not always harmful.

  • Abuse = Causes harm (physical, mental, social, legal).

Q: 3 main factors that shape a person’s drug experience?

A: 1) Drug itself, 2) The person, 3) The setting/environment.

Q: Most common drugs used in the U.S.?

A: Alcohol, tobacco, marijuana.

Q: What is polydrug use?

A: Using more than one drug at the same time.

Q: What is tolerance?

A: Needing more of the drug to get the same effect.

Q: What is withdrawal?

A: Negative symptoms when stopping or reducing drug use.

Q: What does DSM-5 say about substance disorders?

A: Combines “abuse” and “dependence” → now called substance use disorder with 11 criteria.

Chapter 2: Drug Use Yesterday & Today

Q: Why study history of drug use?

A: Helps explain cultural attitudes, laws, and why drugs are used today.

Q: Example of historical use?

A: Opium used in ancient civilizations for pain relief.

Q: Trend in modern use?

A: High rates of alcohol, tobacco, marijuana; ongoing opioid crisis.

Chapter 3: Drugs & the Nervous System

Q: What’s the nervous system’s role in drug use?

A: Drugs affect how brain cells (neurons) communicate.

Q: What are neurotransmitters?

A: Brain chemicals that send messages (like dopamine, serotonin).

Q: How do drugs act on neurotransmitters?

A: They can increase, block, or mimic them.

Q: Main parts of the nervous system?

A: Central (brain & spinal cord) + Peripheral (nerves in body).

Chapter 4: Pharmacology Basics

Q: 4 steps of how drugs move through the body?

A: 1) Absorption, 2) Distribution, 3) Metabolism, 4) Excretion.

Q: What is a dose–response curve?

A: Graph showing how drug effect changes with dose.

Q: What is a half-life?

A: Time it takes for the drug level in body to drop by half.

Chapter 5: Psychopharmacology & New Drugs

Q: What is psychopharmacology?

A: Study of how drugs affect behavior, thinking, mood.

Q: What’s involved in new drug development?

A: Testing safety, effectiveness, side effects before approval.

Q: Why is placebo important in research?

A: Shows if effects are from the drug or just expectation.

Chapter 15: Treatment of Substance Use Disorders

Q: 3 psychological factors in recovery?

A: Motivation to change, self-confidence (self-efficacy), coping skills.

Q: 2 main types of treatment?

A: 1) Medication (e.g., methadone, buprenorphine)

2) Therapy (CBT, motivational interviewing).

Q: What is relapse?

A: Returning to drug use after a period of stopping.

Q: Is relapse failure?

A: No—common part of recovery process.

Q: What’s the Community Reinforcement Approach (CRA)?

A: Treatment that changes lifestyle and uses family/community support.

Q: DSM-5 criteria for substance use disorder?

A: 11 total → grouped as impaired control, social problems, risky use, physical dependence.