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AAPC Med Term/Anatomy/PathoPhysio 3 #bf9eea

CHAPTER 8

Respiratory System

  • cellular respiration involves the breakdown glucose in the presence of oxygen to produce energy in the form of adenosine triphosphate (ATP), carbon dioxide, and water

  • respiration refers to the process of breathing

Roots, Suffixes and Prefixes

  • nas/o - nose

  • rhin/o - nose

  • pharyng/o - pharynx

  • laryng/o - larynx

  • trache/o - trachea

  • bronch/o - bronchus

  • broch/i - bronchus

  • bronchiol/o - bronchiole

  • phren/o - diaphragm

  • phrenic/o - phrenic nerve

  • pleur/o - pleura

  • pulm/o - lung

  • pulmon/o - lung

  • pneumon/o - lung

  • pneum/o - air, gas; respiration, lung

  • pneumat/o - air, gas; respiration, lung

  • spir/o - breathing

  • -pnea - breathing

  • -oxia - level of oxygen

  • -capnia - level of carbon dioxide

  • -phonia - voice

Vocabulary

  • bleb - small collection of air between the lung and the outer surface of the lung (visceral pleura) usually found in the upper lobe

  • commissure - a point or line of union or junction especially between two anatomical parts (oral cavity and nasal cavity in respiratory system)

  • cytology - diagnostic exam of a single cell type, often found in fluid specimens

  • decubitus - posture adopted by a person who is lying down

  • epiglottis - a leaf shaped cartilage that covers the larynx during swallowing to prevent food from entering trachea

  • glottis - below the epiglottis, opening between the vocal folds

  • infundibulum - a funnel shaped cavity or structure, seen between right ventricle that leads to pulmonary artery

  • innominate artery - an artery that supplies blood to the right arm, head and neck direct from the aorta

  • loculated - the process of being divided into compartments by septa

  • meatus - a passage or opening leading to the interior of the body

  • mediastinotomy - procedure in which a tube is inserted into the chest to view tissues and organs in the area between the lung and breastbone and heart

  • pleurodesis - procedure that sticks your lung to your chest wall, removing the space between your lung and pleural space so that fluid or air no longer builds up there

  • pneumothorax - when air leaks into the space between your lungs and chest wall, causing it collapse

  • polypectomy - surgical removal of a polyp

  • Reinke’s space - non-muscle part of the vocal cord, sometimes called the vocal fold, right under its surface

  • rhinosinusitis - inflammation of the nasal cavity and paranasal sinuses

  • sarcois - disease characterized by the growth of tine collections of inflammatory cells (granulomas)

  • VATS - video assisted thoracoscopic surgery, used to diagnose and treat problems in chest

Anatomy

  • upper respiratory

    • includes the nose, throat (pharynx), larynx

    • nose

      • air is taken in through nostrils, warmed, purified and dampened as it enters nasal cavity

      • dirt and foreign material are projected towards the pharynx for expulsion by the cilia (sputum)

      • mucous keeps nasal cavity moist, and blood flow underneath aid in warmth

    • paranasal sinuses

      • four sinuses that drain into each nasal cavity which produce mucus or the respiratory tract

        • frontal

        • maxillary

        • sphenoid

        • ethmoid

    • pharynx (throat)

      • inhaled air travels through mouth and pharynx

      • has 3 regions

        • nasopharynx

          • superior region

          • found behind nasal cavity

        • oropharynx

          • middle region

          • located behind mouth

        • laryngopharynx

          • inferior region

          • located behind larynx

      • houses the tonsils and lymphoid tissues

        • palatine tonsils on soft palate (oropharynx)

        • adenoids in nasopharynx

        • lingual tonsils at very back of tongue

    • larynx

      • voice box, houses vocal cords

      • located just below pharynx

      • made up of 9 pieces of cartilage

        • thyroid cartilage/Adam’s Apple is the largest

  • lower respiratory

    • includes trachea, bronchial tree and lungs

    • trachea

      • windpipe

      • allows the passage of air to travel from either the nose or mouth through the larynx to bronchi of lungs

      • c-shaped rings of cartilage reinforce trachea from collapse

    • bronchia tree

      • made up of trachea and two primary bronchi (resemble an upside down tree)

        • trachael bifurcation into left and right

        • the carina is located at bifurcation

        • right bronchus leading to right lung is shorter and wider

          • divides into 3 secondary bronchi

        • left bronchus leading to left lung

          • divides into 2 branches

        • bronchioles form as tubes decrease in size

        • alveolar ducts

          • miniscule pipes resembling a cluster of grapes that carry air into clusters or sacs where gas is traded between lungs and circulating blood

    • lungs

      • deep fissures or grooves partition each lung into lobes

        • right lung has 3 lobes

        • left lung has 2 lobes

      • each lobe is covered in double-layered membrane called pleura

        • parietal pleura layer

          • outermost, bound to the partition of thoracic cavity

        • visceral pleura layer

          • innermost, bound to the side of the lungs

      • pleural space

        • very slim space filled with fluid-like substance to allow for ease of expansion of the lungs during breathing

      • only organ that can float on water

      • contains about 300 million balloon-like structures called alveoli, which replace carbon dioxide waste in your blood with oxygen

Breathing

  • called pulmonary ventilation

  • inspiration = inhalation

  • expiration = exhalation

  • unconscious task that is regulated by the center of the brain stem

  • eupnea

    • normal RR

    • pt oblivious to their breathing pattern

    • meeting body needs

  • hyperventilation

    • rapid breathing patterns

  • hypoventilation

    • deep or slow and shallow respirations

    • technically doesn’t meet the body needs

    • carbon dioxide levels ride, causing a build up of acid

    • causes sleepiness

  • dyspnea

    • forced or difficult breathing, often connected to hypoventilation

  • inspiration

    • diaphragm contracts and moves in descending motion

    • at the same time, muscles between ribs contract and pull in ascending motion

  • expiration

    • (exhalation)

    • relaxation of diaphragm and elastic recoil of tissue lessening the thoracic volume

    • escalates pressure

Respiratory Diseases

  • Chronic Obstructive Pulmonary Disease (COPD)

    • chronic inflammatory lung disease that causes obstructed airflow from lungs

    • causes strain and labored breathing, especially when emptying lungs

    • irreversible

    • symptoms:

      • SOB

      • wheezing

      • chronic cough

  • Chronic Bronchitis

    • persistent inflammation of the lungs and bronchi

    • acute bronchitis occur temporarily and clears up

    • symptoms:

      • sputum

      • wheezing

      • chest pain

      • SOB

  • Emphysema

    • air sacs in lungs have become damaged, causing inner walls of air sacs to breakdown, erode and separate, reducing surface area of lungs

    • symptoms:

      • dyspnea

      • SOB

  • Influenza

    • viral respiratory infection causing fever, cough, headache, and malaise

    • mortality possible

    • vaccine available to everyone aged over 6 months who does not have a contraindication

  • lung cancer

    • symptoms do not appear until advanced stages

      • chest pain

      • SOB

      • bone pain

      • coughing up blood

      • headache

    • mostly caused by smoking or second hand smoke

      • believed that smoking causes lung cancer by mutilating the cells that actually line the lung

      • carcinogens in smoke cause immediate changes to the lung tissue

      • second hand smoke causes more than 7,300 lung cancer deaths among US nonsmokers each year

      • secondhand smoke increases the risk of breast cancer, nasal sinus cavity cancer, nasopharyngeal cancer in adults and leukemia, lymphoma and brain tumors in children

    • two types of lung cancer:

      • small cell lung cancer

        • commonly materializes exclusively in heavy smokers

        • less common

      • non-small cell lung cancer

        • umbrella term

        • (includes adenocarcinoma, large cell carcinoma, squamous cell carcinoma)

      • often metastasizes to other part of body such brain or bones

      • non curable when spread beyond lungs

  • pleural effusion

    • accumulation of fluid in the pleural space

    • classified as

      • transudates

        • require no treatment

      • exudates

        • require thoracentesis, chest tube drainage, pleurectomy or combination

  • pneumonia

    • infection affecting one or both lungs, causing air sacs to be inflamed and to fill with fluid or pus which will be coughed up as pus or phlegm

    • symptoms:

      • chest pain when breathing and/or coughing

      • fatigue

      • fever, sweats, chills

      • nausea, vomiting, diarrhea

      • cough with phlegm

    • mostly caused by bacteria and viruses in the air we breathe

    • arranged in 4 types of germ classifications that generate the infection

      • community-acquired pneumonia

        • most common type

        • may originate from bacteria, fungi or viruses

      • hospital-acquired pneumonia

        • may become resistant to antibiotics

      • healthcare-acquire pneumonia

        • occurs in pts in long-term care facilities

      • aspiration-acquired pneumonia

        • occurs when pt inhales food, drink, vomit or saliva into their lungs

        • more likely in something disturbs your gag reflex, such as brain injury, swallowing problem or excessive use of substances

  • respiratory failure

    • life threatening impairment of oxygenation, carbon dioxide elimination, or both

    • may occur because of

      • impaired gas exchange

      • decrease ventilation

      • both

    • common manifestations

      • dyspnea

      • use of accessory muscles of respiration

      • tachypnea

      • tachycardia

      • diaphoresis

      • cyanosis

      • altered consciousness

      • eventually, obtundation, respiratory arrest or death

    • treatment is in ICU and involves correction of underlying disorder, use of supplemental oxygen or ventilatory assistance

  • CHAPTER 8 (Respiratory System): Starts on page 1 and ends on page 6.

  • CHAPTER 9 (Digestive System): Starts on page 6 and ends on page 18.

  • CHAPTER 10 (Urinary System): Starts on page 18 and ends on page 25.

  • CHAPTER 10 (Male Reproductive System): Starts on page 25 and ends on page 28.

  • CHAPTER 11 (Female Reproductive System): Starts on page 28 and ends on page 29.

CHAPTER 9

Digestive System

  • consists of the alimentary tract (digestive tract) and it’s accesory organs

  • alimentary/digestive tract

    • long, hollow, muscular tube beginning at the mouth and ending at the anus

    • includes the mouth, pharynx, esophagus, stomach, small intestines and large intestines; and accessory organs like salivary glands, liver, pancreas and gallbladder

Roots, Suffixes and Prefixes

  • abdomin/o - abdomen, abdominal

  • an/o - anus

  • appendic/o - appendix

  • bil/i - bile

  • bilirubin/o - bilirubin, bile pigment

  • bucc/o - cheek

  • cec/o - cecum

  • celi/o - abdomen

  • cheil/o - lip

  • chole/o - gallbladder

  • choleangio/o - bile duct

  • cholecyst/o - gallbladder

  • choledoch/o - common bile duct

  • col/o - large intestine, colon

  • colon/o - large intestine, colon

  • dent/i - teeth

  • dent/o - teeth

  • odont/o - teeth

  • diverticul/o - diverticulum

  • duoden/o - duodenum

  • end/o - within, inner, containing

  • ent/o - with in, inner, containing

  • enter/o - small intestine

  • esophag/o - esophagus

  • gastr/o - stomach

  • gingiv/o - gingivae, gums of the mouth

  • gloss/o - tongue

  • hepat/o - liver

  • herni/o - hernia, rupture, protrusion of a part of a structure through containing tissue

  • ile/o - ileum

  • jujun/o - jejunum

  • labi/o - lips

  • lapar/o - abdominal wall

  • lingu/o - tongue

  • lith/o - stone

  • or/o - mouth

  • pancreat/o - pancreas

  • peritone/o - peritoneum

  • polyp/o - polyp

  • proct/o - rectum

  • pylor/o - pylorus

  • rect/o - rectum

  • sial/o - saliva, salivary gland, salivary duct

  • sialaden/o - salivary gland

  • sigmoid/o - sigmoid colon

  • splen/o - spleen

  • stomat/o - mouth

  • uvul/o - uvula

  • viscer/o - internal organs

  • -ase - enzyme

  • -cele - hernia

  • -chezia - defecation

  • dia- - through, throughout, completely

  • -ectasia - dilation, expansion, distension

  • -ectasis - dilation, expansion, distension

  • emesis - vomiting

  • -lysis - separation, loosening, dissolving, destructiono

  • -ostomy / -stomy - artificial surgical creation of an opening

  • -pepsia - digestion

  • -phagia - eating, swallowing

  • -plasty - plastic repair, plastic surgery, reconstruction

  • -rrhea - flow, discharge

  • -scope / -scopy - involving the use of an instrument for viewing

  • -tomy - incision into, cutting

Digestive Tract

  • primary function is to digest (break down) foods taken into the body using two methods

    • mechanic digestion (mastication / chewing)

      • stomach churns chewed food and small intestines aborbs the food

    • chemical digestion

      • stomach bile, acids and enzymes break up large carbohydrate, lipid, protein and nucleic acid molecules into subcomponents of nutrients

  • the long hollow organs have circular and longitudinal fibers running throughout which enable food to move from organ to organ when they contract; called peristalsis

Common Conditions

  • hernias

    • when the contents of a body cavity bulge out of the area where they usually are contained

    • can be congenital, acquired or recurrent

    • specified categories

      • inguinal hernia

        • occur in the groin and can be either direct or indirect

          • direct hernias arise because of the weakening of the abdominal wall, common in older adults

          • indirect hernias result from protrusion through the internal inguinal ring, often congenital

      • hiatal hernia

        • anatomical abnormalities of the stomach which protrude or herniate through the opening of the diaphragm into the chest

      • umbilical hernia

        • common

        • caused by an opening in the abdominal wall

      • ventral hernia

        • occur at the site of previous abdominal surgery and are called an incisional hernia

      • diaphragmatic hernia

        • occur when there is an abnormal opening in the diaphragm

        • can be acquired or congenital

      • parastomal hernia

        • happen when intestine press outward near a stoma

  • polyps

    • abnormal growth of tissue projecting from mucous membrane frequently occur in the lining of the large intestine, colon

    • shape can be flat, slightly raised or on a stalk (called pedunculated)

    • often benign but can become malignant over time if not removed

    • any PHx or FHx of neoplasm is clinically significant and should be noted in medical record

  • gastrointestinal (GI) bleeding

    • refers to every form of hemorrhage in the GI tract

    • can range from microscopic to massive bleeding

      • massive bleeding can result in hypovolemia, shock or even death

    • has many causes (not limited to)

      • esophageal varices

      • Mallory-Weiss tears

      • peptic ulcer disease

      • diverticular disease

      • hemorrhoids

      • fissures

  • gastroenteritis

    • infection or irritation of the digestive tract, particularly the stomach and intestines

    • most common symptoms

      • nausea

      • vomiting

      • diarrhea

      • abdominal cramps

      • weakness

      • fever

    • caused by either virus or bacteria

    • typically lasts about 3 days

    • children, elderly and vulnerable adults susceptible to dehydration

  • common conditions of small and large intestines:

    • Crohn’s disease

      • chronic inflammatory process of the bowel that often leads to fibrosis and obstructive symptoms

      • can affect any part of Gi tract

        • most involves small bowel, particularly terminal ileum

      • characteristic presentation is abdominal pain and diarrhea, possible complications including combinations of intestinal fistulization, obstruction, hemorrhage, abscess

    • congenital megacolon

      • abnormal dilation of the colon

      • often accompanied by paralysis of peristaltic movement

    • diverticulosis

      • pouches or projections (diverticula) causing muscle weakness in colon wall as it contracts and exerts pressure

      • most frequent in the sigmoid colon

      • can cause changes in bowel function, like discomfort, diarrhea or constipation

      • in advanced stages

        • lower colon may become very fixed, distorted or narrowed

        • thin or pellet-shaped stools may occur, or constipation, and occasional rush of diarrhea

    • diverticulitis

      • inflammation as bacteria in the colon cause infection of the diverticular pockets

      • can be mild with only slight discomfort in left lower abdomen or can be extreme with severe tenderness and fever, requiring treatment and dietary restrictions

      • can cause bleeding and perforation

    • inflammatory bowel disease

      • group of inflammatory conditions of colon and small intestines

      • includes Crohn’s disease and ulcerative colitis

    • irritable bowel syndrome

      • also known as

        • spastic colon

        • spastic colitis

        • nervous of function bowel

      • most often affects large intestine

      • colon does contract normally but in violent disorganized manner; may be exaggerated or sustained for prolonged periods; one area may contract with no regards to another

      • result in changing bowel patterns with constipation and pain being most common

    • Meckle’s diverticulum

      • congenital condition

      • remnant of the connection from yolk sac to small intestine present during embryonic development

      • sometimes contains gastric tissue, sometimes contains pancreatic tissue

      • asymptomatic

      • managed by surgical resection

    • redundant colon

      • congenital variation on the normal anatomy of a colon, longer than normal

      • asymptomatic

      • usually not found until x-ray or colonoscopy performed

    • ulcerative colitis

      • chronic inflammatory disorder

      • causes inflammation and sores in the lining of the rectum and colon

      • ulcers form where inflammation has killed the cells that usually line the colon

      • ulcers will bleed and produce pus

      • inflammation causes colon to empty frequently, resulting in diarrhea

  • common conditions of the rectum and anus

    • hemorrhoids

      • dilated or enlarged varicose veins in and around the anum and rectum

      • may be external (distal end of anal canal) or internal (in the rectum)

      • can slip out of anus (prolapsed)

      • can be complicated by

        • thrombosis

        • strangulation

        • prolapse

        • ulceration

    • rectal prolapse

      • can be

        • complete

          • when full thickness of bowel protrudes through the anus

        • partial

          • mucous membrane lining the anal canal protrudes through anus

      • abscess can occur in the perirectal and perianal areas

    • anal fissures

      • tears in the mucosa and skin of the anal canal due to passing a large stool, straining during childbirth, and laceration from passing a foreign body

    • anal fistulas

      • tiny channels or tracts that develop because of an infection, inflammation, or abscess

      • one opening in anal canal and one in perianal skin, rectum, bladder or vagina

Anatomy

  • mouth

    • associated structures

      • lips

      • soft and hard palates

      • teeth

      • gums

      • tongue

      • salivary glands

    • performs two main functions

      • speech

      • digestion

    • digestive process begins when food enters the mouth

      • teeth and tongue break up food into small particles

      • salivary glands secrete saliva and enzymes that aid in digestion

      • tongue mixes saliva with food and keeps food pressed against the teeth for chewing, pushing it backwards to swallow

    • categories of teeth

      • incisors

        • front of the mouth

        • shaped like chisels

        • use in biting off large pieces

        • 8 total, 4 top and 4 bottom

      • cuspids

        • point teeth immediately behind incisors, “canines”

        • used for grasping or tearing

        • 4 total, 2 top and 2 to bottom

      • molars

        • flattened teeth used for grinding food

        • farthest back in mouth'

        • number can vary

    • common conditions:

      • cleft lip and/or palate

        • congenital condition

        • resulting from abnormal facial development in gestation

        • causing fissure, gap or opening deformity

        • affecting lip, soft palate, hard palate, or nasal cavities

        • can be corrected with surgery

  • pharynx

    • 5” tube immediately behind the mouth

    • serves as an airway and passageway for food

    • aids in the closure of the nasopharynx and larynx when swallowing to keep food out of respiratory tract

    • common condition:

      • dysphagia (swallowing disorder)

        • causes impairment of the movement of solids or fluids from the mouth, down the throat, and into the stomach

        • can have sever effect on caloric intake and nutritional status

        • may affect ability to swallow liquids, solids or both

        • may make individual susceptible to pneumonia when swallowed substances are inhaled into lungs

  • esophagus

    • long, straight tube about 10” long

    • descends from pharynx, passes through diaphragm, continues into stomach

      • diaphragm

        • muscular and membranous partition that separates the chest cavity from abdominal cavity

    • peristalsis moves food to stomach

    • common conditions:

      • Barrett’s esophagus

        • abnormal growth of stomach or intestinal cells at the distal end of the esophagus

        • leads to cancer of lower esophagus

        • may develop because of chronic gastroesophageal reflux disease, exposing esophagus to stomach acids

      • esophagitis

        • inflammation of the lining of the esophagus

        • untreated, becomes very uncomfortable causing problems with swallowing, ulcers, and scarring

        • caused by infection or irritation

          • candida

          • herpes

          • meds like aspirin or NSAIDs

        • can cause the esophagus to constrict, causing esophageal stricture

      • esophageal varices

        • extremely dilated submucosal veins in the lower end of esophagus

        • mostly caused by portal hypertension (portal vein to the liver)

        • strong tendency to develop bleeding

      • Mallory-Weiss tear

        • occur in the mucous membrane of esophagus, where it connects to stomach

        • usually caused by forceful or long-term vomiting or coughing, or by epileptic convulsion

        • may be followed by vomiting bright red blood or by-passing blood in stool

  • stomach

    • large chamber that receives solids, semisolids and liquids from the esophagus

    • has four main parts

      • cardia

      • fundus

      • body (corpus gastricum)

      • antrum (pylorus)

    • digests food and passes the chyme (partially digested food) into the duodenum (upper part of the small intestine)

    • common condition:

      • gastritis

        • acute or chronic inflammation of the stomach

        • commonly caused by bacterium (helicobacter pylori, H. pylori)

        • can lead to ulcers or cancer

        • long-term use of NSAIDs or alcohol also a cause

      • peptic ulcer disease

        • may be referred to as gastric or stomach ulcers

        • sore or opening in the inner lining of the stomach or duodenum

        • ulcers develop when protective layer is broken down and digestive juices can damage esophagus

        • most common causes

          • H. pylori infections

          • prolonged use of NSAIDs

  • small intestines

    • coiled muscular tube that occupies the central and lower abdomen

    • divided into three portions

      • duodenum

        • first portion

        • connected to stomach

        • about 10” long

        • small ducts from pancreas, liver and gallbladder open into via hepatopancreatic ampulla (ampulla of Vater)

      • jejunum

        • middle portion

        • about 7.5 feet long

      • ileum

        • last and longest portion

        • about 12 feet long

        • fluid contents moved to it by vigorous peristaltic waves

        • most of the absorption of food happens here

        • connected to large intestines

  • large intestines

    • the colon, plus rectum and anal canal

    • about 5 feet long and 2.5 inches in diameter

    • water is reabsorbed as the food material travels through the large intestine and eventually is eliminated from the body

    • stores unabsorbed food material

    • begins just after the ileocecal valve at the cecum, with appendix attached at the bottom

    • four portions to the colon:

      • ascending

        • proceeds from ileocecal valve upward to hepatic flexure on right side of abdomen

      • transverse

        • turns downward at the splenic flexure

      • descending

        • gives way to sigmoid colon

        • ends at rectum

      • sigmoid pelvic

    • internal and external anal sphincters at the terminus of rectum control flow of fecal material leaving body

    • common conditions of small and large intestines:

      • Crohn’s disease

        • chronic inflammatory process of the bowel that often leads to fibrosis and obstructive symptoms

        • can affect any part of Gi tract

          • most involves small bowel, particularly terminal ileum

        • characteristic presentation is abdominal pain and diarrhea, possible complications including combinations of intestinal fistulization, obstruction, hemorrhage, abscess

      • congenital megacolon

        • abnormal dilation of the colon

        • often accompanied by paralysis of peristaltic movement

      • diverticulosis

        • pouches or projections (diverticula) causing muscle weakness in colon wall as it contracts and exerts pressure

        • most frequent in the sigmoid colon

        • can cause changes in bowel function, like discomfort, diarrhea or constipation

        • in advanced stages

          • lower colon may become very fixed, distorted or narrowed

          • thin or pellet-shaped stools may occur, or constipation, and occasional rush of diarrhea

      • diverticulitis

        • inflammation as bacteria in the colon cause infection of the diverticular pockets

        • can be mild with only slight discomfort in left lower abdomen or can be extreme with severe tenderness and fever, requiring treatment and dietary restrictions

        • can cause bleeding and perforation

      • inflammatory bowel disease

        • group of inflammatory conditions of colon and small intestines

        • includes Crohn’s disease and ulcerative colitis

      • irritable bowel syndrome

        • also known as

          • spastic colon

          • spastic colitis

          • nervous of function bowel

        • most often affects large intestine

        • colon does contract normally but in violent disorganized manner; may be exaggerated or sustained for prolonged periods; one area may contract with no regards to another

        • result in changing bowel patterns with constipation and pain being most common

      • Meckle’s diverticulum

        • congenital condition

        • remnant of the connection from yolk sac to small intestine present during embryonic development

        • sometimes contains gastric tissue, sometimes contains pancreatic tissue

        • asymptomatic

        • managed by surgical resection

      • redundant colon

        • congenital variation on the normal anatomy of a colon, longer than normal

        • asymptomatic

        • usually not found until x-ray or colonoscopy performed

      • ulcerative colitis

        • chronic inflammatory disorder

        • causes inflammation and sores in the lining of the rectum and colon

        • ulcers form where inflammation has killed the cells that usually line the colon

        • ulcers will bleed and produce pus

        • inflammation causes colon to empty frequently, resulting in diarrhea

    • common conditions of the rectum and anus

      • hemorrhoids

        • dilated or enlarged varicose veins in and around the anum and rectum

        • may be external (distal end of anal canal) or internal (in the rectum)

        • can slip out of anus (prolapsed)

        • can be complicated by

          • thrombosis

          • strangulation

          • prolapse

          • ulceration

      • rectal prolapse

        • can be

          • complete

            • when full thickness of bowel protrudes through the anus

          • partial

            • mucous membrane lining the anal canal protrudes through anus

        • abscess can occur in the perirectal and perianal areas

      • anal fissures

        • tears in the mucosa and skin of the anal canal due to passing a large stool, straining during childbirth, and laceration from passing a foreign body

      • anal fistulas

        • tiny channels or tracts that develop because of an infection, inflammation, or abscess

        • one opening in anal canal and one in perianal skin, rectum, bladder or vagina

  • liver

    • second largest organ in the body (after skin)

    • weighs about 4 pounds

    • lies in upper abdomen, right side, under diaphragm and above duodenum

    • has 4 lobes

      • right lobe

      • left lobe

      • quadrate lobe

      • caudate lobe

    • cannot live without liver due to numerous functions

      • proteins digested become amino acids, with by-product ammonia which is toxic to cells; liver converts ammonia into urea which is excreted

      • converts glucose into glycogen or fat

      • produces bile salts, aiding the emulsification of fat for absorption into intestines

    • only organ able to regenerate itself, which is why an adult can donate a portion to a child (usually regrowing within six weeks)

  • pancreas

    • soft, oblong gland about 6” long and 1” thick

    • beneath the great curvature of the stomach

    • has 5 parts

      • head

      • neck

      • body

      • tail

      • uncinate process

    • empties digestive fluid (mixture of enzymes) into duodenum and insulin into bloodstream

    • insulin is produced inside pancreas

      • in islets of Langerhans

      • by beta cells

      • allows muscle, fat, and liver cells to absorb sugar in blood stream

    • common conditions:

      • pancreatitis

        • inflammation of pancreas

        • acute or chronic

        • digestive enzymes get into tissue of organ (rather than staying within the duct) causing severe damage to pancreas

        • commonly caused by

          • binge drinking alcohol

          • gallbladder disease

          • certain drugs like diuretics

          • extreme high blood fat level (triglycerides)

  • gallbladder

    • sac-like structure attached to the inferior surface of the liver

    • serves as a reservoir for bile

    • periodically empties into the duodenum by way of cystic ducts

Vocabulary

  • alimentary limb - created during different GI surgeries, accepts incoming food

  • Ampulla of Vater - opening in duodenum where pancreatic and bile ducts release into intestines

  • anoscopy - procedure to scope the anus

  • antimesenteric - part of the intestine that lies opposite the mesenteric attachment

  • appendiceal orifice - opening of appendix which leads to cecum

  • bariatric surgery - gastric restrictive procedures to treat morbid obesity

  • barium enema - radiographic contract medium enhanced examination of the colon

  • biliary - gallbladder, bile or bile duct

  • biliopancreatic - bile and pancreatic fluids

  • biliopancreatic limb - created during gastric surgeries, located at beginning of small intestine

  • buccal - pertaining to cheek

  • calculus - concreating of mineral salts, also called a stone

  • cholangiogram - radiographic imaging of bile ducts

  • cholangiopancreatography - radiographic recording of biliary system and pancreas

  • colectomy - excision of part of colon

  • cholecystectomy - surgical removal of the gallbladder

  • cholelithiasis - gallstones

  • cholecystoenterostomy - creation of a connection between the gallbladder and intestine

  • Crohn’s disease - regional enteritis

  • dentate line - line which divides upper two-thirds and lower third of anal canal

  • duodenography - radiographic recording of the duodenum

  • enteroenterostomy - anastomosis between one part of small bowel and another part of small bowel, used to restore bowel continuity after resection of bowel segment

  • enterolysis - releasing of adhesions of intestine

  • epigastrium - part of the abdomen between the bottom of the rib cage and belly button

  • epiglottidectomy - excision of covering of larynx

  • esophageal - pertaining to esophagus

  • esophagogastroduodenoscopy - scoping of the esophagus, stomach and duodenum

  • eventration of intestines - protrusion of intestines through abdominal wall

  • evisceration - pulling the viscera outside of the body through incision

  • exenteration - major operation during which an organ and its adjacent structures are removed

  • exstrophy - condition in which the bladder is turned inside out

  • exteriorization - expose an internal structure outside the body for observation, surgery or experimentation, such as creating passage from bladder to abdominal wall

  • femoral hernia - intestines protrudes along femoral canal

  • fundoplasty - repair of the bottom of an organ or muscle

  • gastrojejunal anastomosis - surgical procedure in which a connection is mad between the stomach and the proximal loop of the jejunum

  • gastrostomy - surgical opening made between stomach and abdominal wall

  • hematemesis - vomiting blood

  • hemicolectomy - surgical removal of half the colon

  • ileocolic arcade - loops of arteries around the jejunum and ileum

  • ileostomy - artificial opening between ileum and abdominal wall

  • incarcerated - constricted irreducible hernia that maybe obstruct organ it is contained within

  • intussusception - slipping of one part of intestine into another part

  • jejunostomy - artificial opening between jejunum and abdominal wall

  • lumbar hernia - posterior abdominal wall or retroperitoneal outpouching occurring between 12th rib and iliac crest

  • marsupialization - produce that creates an exterior pouch from an internal abscess

  • mesenteric - fold of membrane that attaches intestine to abdominal wall

  • monitored anesthesia care (MAC) - conscious sedation, where patient remains aware of their surroundings yest still remains calm, constantly monitored by anesthesiologist

  • mucosal incision - incision into mucosal layer of hollow organ wall

  • nasogastric tube - feeding/medication tube to the stomach through the nose

  • peritoneal cavity - space within the abdomen that contains the intestines, stomach, and liver

  • pneumoperitoneum - presence of air in peritoneal cavity

  • proctitis - inflammation of the lining of the rectum

  • prolapse - internal hemorrhoid that descends past anal sphincter

  • rectocele - herniation of the rectum into the vagina

  • seromyotomy - incision in the wall of a hollow organ that involves the serosa and muscularis but mucosa

  • small bowel - long tube that carries digested food between stomach and large intestine

  • sphincter - muscular ring around a lumen, or hollwo structure

  • stoma - hole created for colostomy or ileostomy appliance

  • stomatitis - inflammation of the mucous membrane of the mouth

  • strangulation (hemorrhoidal) - condition that can happen to hemorrhoids in which the blood supply has become occluded by constricting action of the anal sphincter

  • terminal ileum - most distal segment of the small bowel, just before the small bowel connects to the colon

  • ulceration - inflammation or necrotic changes of the tissue

  • umbilical hernia - protrusion of internal organs through the abdominal wall around the umbilicus

  • uvulopalatopharyngoplasty - surgery to open upper airways by taking out extra tissue in the throat

  • Warthin’s tumor - tumor found in the salivary gland

Abbreviations

  • EGD - esophagogastroduodenoscopy

  • ERCP - endoscopic retrograde cholangiopancreatography

  • GERD - gastroesophageal reflux disease

  • GI - gastrointestinal

  • HJR - hepatojugular reflux

  • IBD - inflammatory bowel disease

  • IBS - irritable bowel syndrome

  • LLQ - left lower quadrant

  • LUQ - left upper quadrant

  • NG - nasogastric

  • PEG - percutaneous endoscopic gastrostomy (tube)

  • PEH - paraoesophageal hernia

  • PUD - peptic ulcer disease

  • RLQ - right lower quadrant

  • RUQ - right upper quadrant

CHAPTER 10

Urinary System

  • produces urine for excretion of metabolic waste, and fluid balance

  • plays an important role in blood pressure control within the body

  • four basic parts for females and five basic parts for males

    • two kidneys

    • two ureters

    • one bladder

    • one urethra

    • prostate gland (males only)

Roots, Suffixes and Prefixes

  • calic/o - calyx

  • cali/o - calyx

  • cyst/o - filled sac or pouch, cyst, bladder, urinary bladder

  • dips/o - thirst

  • glomerul/o - glomerulus

  • hydr/o - water, fluid

  • ket/o - ketone bodies

  • lith/o - calculus, stone

  • nephr/o - kidney

  • pyel/o - renal pelvis

  • ren/o - kidney

  • trig/o - trigone region, kidney

  • ur/o - urine, urinary tract

  • ureter/o - ureter

  • urethr/o - urethra

  • urin/o - urine

  • vesic/o - urinary bladder

  • -lysis - separation, loosening, dissolving, destruction

  • -uria - urination or urinary

Anatomy

  • kidneys

    • bean shaped organs, approximately the size of a fist

    • located near the middle of the back, bilateral to the spine

    • filter urea (waste) and excess fluid from blood

      • using tiny filter units called nephrons

      • nephron

        • consists of glomerulus (ball of capillaries) and a renal tubule

      • urea

        • produced when foods are broken down

        • carried in bloodstream to kidneys

        • combined with water, and other waste substances forms urine after passing through nephron

    • works with lungs, skin and intestine to keep chemicals and water balanced

  • ureters

    • muscular tube carrying urine from the kidneys to bladder

      • originate in renal pelvis and ends in bladder

    • receives urine through major calyces

    • approx. 12” long and 3-4 mm in diamter

    • muscles in wall constantly tight and relax (peristalsis) to force urine down

    • urine allowed to stand still or reflux can cause a kidney infection

    • ureterovesical junction

      • anatomical area where ureters join the bladder

      • has 3 major components

        • lower ureter

        • trigone muscle

        • adjacent bladder wall

  • urinary bladder

    • hollow, muscular, expandable organ collecting urine

    • held in place by ligaments attached to other organs and by pelvic bones

    • stores urine until nerves from bladder signal brain that bladder is full

      • brain signals bladder to tighten and sphincter muscles to relax

      • urine exits through urethra

  • urethra

    • tube connecting urinary bladder to outside of body

    • in males

      • is the conduit for fluid waste and semen

      • shaped like an S to follow line of the penis

      • prostatic urethra

        • portion of urethra passing along neck of urinary bladder, and through prostate gland

        • designed to accept drainage from tiny ducts within prostate

        • equipped with two ejaculatory tubes

        • due to this portion, males who have prostate issues tend to exhibit urinary dysfunction

    • in females

      • straight

      • approx. 4 cm long

      • leads out of body via urethral orifice

      • has no reproductive function

    • bladder muscles will tighten and squeeze urine into urethra

    • bladder neck

      • proximal opening of urethra

      • in men, adjacent from prostate gland

      • if it does not open and close properly may become obstructed

        • in men, caused by enlarged prostate

        • in women, caused by pelvic prolapse

Common Conditions

  • chronic kidney disease (CKD)

    • progressive disorder in which kidneys are damaged and not functioning properly

    • causes excess fluid and toxin build up

    • urine production decreases

    • hypertension begins to rise, meaning less filtering happens

    • 5 stages

      • CKD I - CKD V

        • CKD III has two substages

      • stages determined by glomerular filtration rate (GFR)

        • how much blood is being filtered by glomeruli, lower number signifies more severe disease development

    • irreversible

    • when kidneys stop functioning pt is in end stage renal disease (ESRD)

      • requires the start of dialysis

    • treatment:

      • diet

      • medication

      • control of disease processes (DM, HTN)

      • dialysis, when required

        • two types

          • hemodialysis

            • involves accessing pt’s blood stream through special surgical tunnel and passing blood into external machine to filter waste, toxins and excess fluid

            • typically done 3-4 times a week for a minimum of 4 hours

          • peritoneal dialysis

            • filling abdomen with fluid called dialysate

            • over 8 to 24 hours period, dialysate pulls toxins and waste from blood via osmosis before being drained from abdomen

  • acute renal failure and acute kidney injury

    • ARF and AKI

    • caused by injury, severe illness, heart attack and anaphylactic reactions

    • reversible

      • some meds can initially cause AKI that resolves after med adjustment

  • urinary incontinence

    • inability to control urine leakage form bladder

    • numerous causes, which vary depending on gender

    • 5 different types

      • stress

        • occurs within in activity such as coughing or sneezing

      • urge

        • sudden need to urinate followed by involuntary release of urine

      • mixed

      • overflow

      • functional

    • can be diagnosed symptomatically or by urodynamic testing

      • urodynamic testing

        • done by urologist or gynecologist

        • completed with a mix of tests

  • hydronephrosis

    • dilation of kidney and renal pelvis due to an obstruction causing excess fluid and urine accumulation

      • causes of obstruction include urinary reflux, stones or cancers

  • polyuria

    • excessive production and passage of urine, often occurring with polydipsia

    • often a symptom of other conditions like DM

  • hematocele

    • blood silled sac found within the body area

Surgical Approach Procedures

  • surgical roots, suffixes and prefixes

    • -centesis - to puncture

    • -clasis - surgical break or fracture

    • -desis - fixation, binding

    • -ectomy - surgical removal

    • -graphy - imaging

    • -lysis - to free up

    • -orraphy - surgical suture

    • -opexy - surgical fixation of an organ

    • -otomy - incision, to cut open

    • -scopy - observation, related to endoscope

    • -plasty - remodel or repair

  • through a natural opening or orifice

    • minimally invasive

    • ex: transurethral resection of prostate (TURP) or cystoscopy

  • percutaneous

    • through the skin

    • includes puncturing skin to gain access to body cavity or organ with a catheter or probe

  • endoscopic or laparoscopic

    • minimally invasive

    • uses endoscope (flexible tube with light and camera) to examine or treat internal organs

    • performed through natural openings or percutaneously

  • open surgical approach

    • use of scalpel to open area under treatment

    • often used to treat cancers, pelvic adhesions or elarged organ

    • in urological surgery, the direct and depth of dissection is important to note

      • laparotomy (vertical)

      • Pfannenstiel (horizontal)

      • was peritoneum, bladder or prostate opened?

      • did they repair or remove any of the reproductive organs?

    • inguinal incision typically made in groin for procedure involving testicles or spermatic cord

Diagnostic Procedures

  • cystoscopy

    • scope inserted into bladder through urethra to examine the inside

  • prostate specific antigen (PSA) blood test

    • measure the level of a specific protein made by prostate

    • the higher the PSA result the higher the possibility of infection or cancerous condition

  • digital rectal examination (DRE)

    • physician places a finger into patient’s rectum and checks for enlargement or masses

  • prostate biopsy

    • removal of tissue samples following continuous high PSA blood test levels or suspected enlarged or hardened prostate to determine diagnosis

    • completed either transrectally or transperineally

      • transrectal

        • most common

        • placing a needle through the wall of the rectum into the prostate

        • typically done with ultrasound guidance

        • completed in physician’s office

      • transperineal

        • needle place into prostate through the perineum

        • done in a hospital

        • usually done with CT or MRI guidance

    • if cancer cells are detected, a Gleason score is assigned by a pathologist to indicate how fast-growing it is and how likely it is to spread (higher score means more aggressive)

  • blood urea nitrogen (BUN) test

    • blood test to detect levels of urea nitrogen

    • urea nitrogen and creatinine levels from food break down increase when kidneys are not fully functioning

  • urodynamic testing

    • assesses the function of the bladder

    • comprised of several tests for

      • bladder capacity

      • pressure

      • bladder muscle activity

      • urine flow rate

    • post-void ultrasound maybe be performed to check for residual urine

Therapeutic Procedures

  • transurethral resection of a bladder tumor (TURBT)

    • a cystoscope placed through urethra into bladder for examination, and resection or removal of tumors found within

  • ureterolithotomy

    • surgical removal of stones lodged in the ureter by making an incision into ureter

  • nephrolithotomy

    • incision for the removal of kidney stones

  • nephrotomy

    • surgical incision into kidney

  • extracorporeal shock wave lithotripsy (ESWL)

    • surgical procedure to crush or break down calculi in kidney or ureter either externally (extracorporeal) or internally using (cystourethroscopy)

Vocabulary

  • albuminuria - presence of serum protein (albumin) in the urine can be a sign of kidney disease

  • bacteriuria - bacteria in the urine

  • chronic kidney disease (CKD) - a chronic diase in which the kidney’s ability to filter waster from the blood declines slowly

  • cystectomy - excision of all or part of the bladder, removal of a cyst

  • cystitis - inflammation of bladder

  • cystocele - hernia of the bladder protruding into the vagina

  • cystolithectomy - excision of a calculus (stone) from the bladder

  • cystopexy - surgical fixation of the bladder to abdominal wall

  • cystoplasty - surgical repair of the bladder

  • cystorrhagia - blood bursting forth from the bladder

  • dialysis - separation of waste material from blood to maintain fluid, electrolyte and acid-base balance in impaired kidney function

  • dysuria - difficult or painful urination

  • glomerulonephritis - inflammation of the glomeruli, tiny filters of the kidney

  • hematuria - blood in urine

  • hydronephrosis - condition caused by excess fluid or urine accumulated kidney and renal pelvis due to obstruction

  • incontinence - inability to control urine leakage from bladder

  • interstitial cystitis - condition of sever, chronic pain, pressure, or discomfort in the pelvic region and bladder

  • nephrectomy - remove of one or both kidneys

  • nephritis - inflammation of the kidney

  • nephrolithiasis - condition of having stones or calculi in the kidney

  • nephrologist - specialist in disease of the kidney

  • nephropathy - disease of the kidney

  • nephrosclerosis - hearing of the kidney

  • polycystic kidney disease - hereditary disorder developing numerous fluid filled cysts in the kidneys, causing enlargement and failure

  • polyuria - excessive urination

  • pyelocystitis - inflammation of the bladder and renal pelvis

  • pyelonephritis - inflammation of the kidney and renal pelvis

  • pyelostomy - procedure to form an artificial opening in the renal pelvis

  • pyuria - pus in the urine

  • renal calculi - kidney stone

  • renal agenesis - condition where one or both kidneys fail to form at birth

  • uremia - excess urea and other nitrogenous waste in blood

  • ureteroplasty - surgical repair of ureter

  • urethralgia - pain in the urethra (urethrodynia)

  • urinalysis - examination of the urine to detect abnormalities by various diagnostic methods

  • urologist - physician treating disease of the urinary system

  • vesicoureteral reflux (VUR) - vesicoureteral reflux is urine flow from the bladder back into the ureter and kidneys, which can lead to bacterial infection and an increase in hydrostatic pressure, causing kidney damage

Abbreviations

  • ARF - acute renal failure

  • BUN - blood urea nitrogen

  • CKD - chronic kidney disease

  • CMG - cystometrogram

  • CPP - chronic pelvic pain

  • CRF - chronic renal failure

  • ESRD - end stage renal disease

  • ESWL - extracorporeal shock wave lithotripsy

  • GFR - glomerular filtration rate

  • IC - interstitial cystitis

  • IVP - intravenous pyelogram

  • KUB - kidney ureter bladder

  • LUTS - lower urinary tract symptoms

  • PVR - post void residual

  • RCC - renal cell carcinoma

  • SUI - stress urinary incontinence

  • TURBT - transurethral resection of bladder tumor

  • UA - urinanlysis

  • UDS - urodynamics

  • UTI - urinary tract infection

  • VCUG - voiding cystourethrogram

  • VUR - vesicoureteral reflux

Male Reproductive System

Roots, Suffixes and Prefixes

  • andr/o - male

  • baln/o - head of penis

  • crpyt/o - hidden

  • epididym/o - epididymis

  • meat/o - meatus or opening

  • orchi/o - testes

  • orchid/o - testes

  • peni/o - penis

  • phallo/o - penis

  • osche/o - scrotum

  • prostat/o - prostate

  • semin/o - semen

  • sperm/o - sperm, spermatozoon

  • spermato/o - sperm, spermatozoon

  • test/o - testis, testicle

  • vas/o - vessel, duct, vas deferens

  • vasicul/o - seminal vesicle

Anatomy

  • testes

    • produce and store sperm cells

    • surround on front and sides by serous membrane (tunica vaginalis)

    • oval shaped

    • about 5 cm (2 in) in length, and 3 cm (1 in) in diameter in adult males

    • scrotum

      • holds testicles outside the body

      • shrinks to hold closer to body to conserve heat when cold, becomes larger to get rid of excess heat

    • need to be kept colder than body temperature to create sperm

    • spermatic cord

      • bundle of nerves and blood vessels that connect testicles to abdominal cavity

    • considered part of the endocrine system since they secrete hormones

    • during development, pituitary gland signals testicles to produce testosterone

      • causes cells to transform into sperm cells

    • seminiferous tubule

      • system of tiny tubes where sperm is developed

  • epididymis and vas deferens

    • epididymis

      • coiled tube within scrotum that connects testicles to vas deferens

      • where sperm cells complete their development

    • sperm cells uses their tails to push themselves from the seminiferous tubules into the epididymis

    • after maturing, sperm moves to vas deferens

    • vas deferens

      • muscular tube that transports semen from epididymis into pelvis, then connects to prostatic urethra

  • seminal vesicles

    • pair of tubular sac-like glands

    • located behind bladder and above prostate gland

    • about 5 cm (2 in) in length

    • secrete much of the fluid that creates semen

    • together with prostate gland (accessory sex glands) provide fluids that lubricate the duct system and nutrients to sustain sperm

  • ejaculatory duct

    • short tube formed by joining of vas deferens and excretory duct or seminal vesicles

    • passes through prostate gland and opens into prostatic urethra

    • as semen pass through, it receives fluids from both prostate gland and seminal vesicles

  • prostate gland

    • surrounds the neck of the bladder and urethra in males

    • approx. the size of a walnut

    • partly muscular, partly glandular

    • secretes the liquid portion of seminal fluid which carries sperm

    • during orgasm

      • muscles of the prostate propel prostate fluid and sperm into urethra

      • semen leaves through the tip of the penis

    • can be palpated by a physician during digital rectal examination

  • bulbourethral glands (Cowper’s glands)

    • two accessory glands located below the prostate

    • secrete pre-ejaculatory fluid which lubricates the urethra and neutralizes the acidity of remaining urine

  • penis

    • made up of two parts

      • shaft

        • made up of 3 columns of erectile tissue

          • two called corpus cavernose

          • one called corpus spongiosum

            • surrounds urethra

          • expand with increased blood flow causing erection

      • glans (head)

        • at the end is a small slit called meatus (where semen and urine exit the body)

    • foreskin or prepuce

      • loose skin covering the end of the penis

Common Conditions

  • spermatocele

    • noncancerous cyst-like, fluid and semen filled sac found within the testicle and/or epididymis

    • can be smalll and found incidentally on exam or large and causing pain or discomfort requiring treatment

  • orchitis

    • inflammation of the testicle

  • epididymitis

    • inflammation of epididymis

  • prostatitis

    • inflammation of the prostate gland causing painful or difficult urination and occasionally flu-like symptoms

    • usually due to an infection

    • can be acute or chronic

Procedures

  • orchiectomy

    • removal of a testicle

    • “radical” means removal of additional tissue and lymph nodes around testicle that could be cancerous

  • orchiopexy

    • surgical procedure that moves and secures testes to scrotum

    • may be performed to correct undescended testicle or to correct testicular torsion

  • circumcision

    • removal of the prepuce (foreskin) and glans (tip) of penis

    • may treat conditions like phumosis, too tight, or paraphimosis (becomes trapped behind the glans)

  • vasectomy

    • relatively permanent surgical form of male sterilization

    • cut, puncture or removal of part of vas deferens, thereby severing the tub that delivers sperm

    • vas deferens

      • 2 muscular tubes that moves sperm from the epididymis and testicles

    • may be performed unilaterally or bilaterally

    • reversal success not guaranteed but can be attempted using vasovasostomy or vasovasorrhaphy

Vocabulary

  • benign prostatic hyperplasia - prostate enlargement cause by an overgrowth or prostatic cells or tissue, tends to cause urinary symptoms

  • chordee - congenital condition of the penis which the head of the penis bends abnormally

  • circumcision - removal of foreskin

  • cryptorchidism - condition of one or both testes not descending into scrotum

  • epispadias - congenital deformity of the penis where the urethral opening (meatus) in found on the top or upper portion of penis rather than the usual through the tip

  • erectile dysfunction - inability to get or maintain an erection

  • gleason score - grade assigned by pathologists to indicate growth rate and aggressiveness of prostate cancer and how likely it is to spread (lower number, slower growing)

  • hypospadias - congenital deformity of the penis where the urethral opening (meatus) is on underside of penis or perineum rather that usual through the tip

  • orchiectomy - excision of a testicle

  • phimosis - condition of foreskin too tight to retract over glans, circumcision made be necessary

  • priapism - prolonged erection lasting more than 4 hours

  • prostatalgia - pain in the prostate

  • prostatectomy - surgical removal of part or all of prostate gland

  • prostatic hypertrophy - prostate enlargement due to increase in size of prostate cells rather than the growth of new prostate tissue

  • testicular torsion - twisting of the testicle inside of the scrotum, which may interfere with blood flow to the testicle causing the tissue to eb deprived of oxygen

  • vasectomy - form of male sterilization by which the vas deferens is cut or puncture to prevent sperm from being ejaculated

Abbreviations

  • BPH - benign prostatic hyperplasia

  • ED - erectile dysfunction

  • GG - Gleason grade

  • LUTS - lower urinary tract symptoms

  • PCa - prostate cancer

  • PIN - prostatic intraepithelial neoplasia

  • PSA - prostate specific antingen

  • TUMT - transurethral microwave thermotherapy

  • TUNA - transurethral needle ablation

  • TURP - transurethral resection of the prostate

CHAPTER 11

Female Reproductive System

Roots, Suffixes Prefixes

  • abort/i - abortion, miscarriage

  • amin/o - amniotic sac

  • cervic/o - cervic

  • chori/o - membrane or sac, sac enclosing a fetus

  • chroiod/o - membrane or sac, sac enclosing a fetus

  • colp/o - vagina

  • epis/o - vulva

  • fet/o - fetus

  • gamet/o - egg or sperm

  • gest/o - pregnancy

  • gonad/o - sex glands (ovaries, testes)

  • gyn/o - woman

  • gynec/o - woman

  • hyster/o - uterus, womb

  • labi/o - lips

  • lact/i - milk

  • lact/o - milk

  • mamm/o - breast

  • mast/o - breast, mammary gland

  • men/o - menstruation

  • mens/o - menstruation

  • metra/o - uterus

  • metr/o - uterus

  • metri/o - uterus

  • nat/o - birth

  • omphal/o - navel

  • o/o - ovum, egg cell

  • oophor/o - ovary

  • ov/o - ovum, egg cell

  • ov/i - ovum, egg cell

  • ovul/o - ovum, egg cell

  • ovari/o - ovary

  • pelv/i - pelvic

  • pelv/o - pelvic

  • pelvi/o - plevic

  • pub/o - pubis

  • salping/o - oviduct, fallopian tube

  • toc/o - childbirth

  • uter/o - uterus

  • vagin/o - vagina

  • vulv/o - vulva

Anatomy

Uterus and Cervix

  • comprised of 3 layers

    • endometrium

      • inner layer

      • thickens and slough each month during menstrual cycle

      • if pregnancy occurs, thickened lining provides home and nutrients for embryo

    • myometrium

      • middle layer

      • muscle fibers running horizontally, vertically and diagonally to provide strong contractions during labor and delivery

    • perimetrium

      • serous outer layer

      • secretes lubrication fluid to reduce friction

  • 3 distinct regions

    • uterine fundus

      • uppermost portion, closest to tube

    • corpus

      • body of uterus

      • middle portion

    • uterine isthmus

      • lower portion

      • narrows down and communicated with the uterine end of the cervix (cervix uteri)

  • cervix uteri

    • lower portion of the cervix that protrudes into vaginal canal

  • fornix (fornices)

    • anterior and posterior recess in upper vagina surrounding vaginal attachment to cervix

  • external os

    • opening in the cervix, near the vagina

    • communicates with the vagina

  • internal os

    • opening in the cervix, near the uterus

    • communicates with the corpus of the uterus

Uterine Adnexa

  • fallopian tubes

    • also called ovidcuts, uterine tubes, tubes, and salpinges (singular: salpinx)

    • one on either side of the uterus, arching over ovaries

    • infundibulum

      • distal end of fallopian tubes

    • fimbriae

      • (“fingers”)

      • help capture the ovum (egg, or oocyte) at ovulation as it travels into the tubes and uterus

    • ampulla

      • section of the tube at its widest and longest (7-8 cm in length)

      • fertilization often takes place at this section of the tube

      • narrows as it approaches the uterine horns

  • ovaries

    • actual egg producing reproductive organs

    • produce hormones related to female reproductive cycles

    • part of both endocrine and reproductive systems

  • broad ligament

    • thin sheet of peritoneum that drapes over uterus and fallopian tubes to connect them to later wall of pelvis

    • divided into 3 parts

      • mesosalpinx

        • over the fallopian tubes

      • mesovarium

        • over the ovaries

      • mesometrium

        • largest subsection

        • surrounds uterus

  • cardinal ligament

    • ligamentum transversum cervicis

    • supports the connection between the cervix and pelvic wall

  • round ligament

    • ligamentum teres

    • thickening of the broad ligament as it comes off the anterior surface of uterus, connecting the anterior uterine horns to the anterior abdominal wall

  • utero-ovarian (UO) ligament

    • “ovarian ligament”

    • connects the uterus to the ovary

  • uterosacral ligament

    • connects the back of uterus at the cervix level to the sacrum

    • integral to structural support of the uterus, preventing uterine prolapse into vagina

Vagina

  • tubular, muscular canal leading from the uterus to outside the body

    • top of vagina surrounds cervix

    • distal vagina opens to vulva and perineum

  • vaginal septum

    • congenital partition or septum of vaginal canal

      • longitudinal

        • creating a double vagina

      • transverse

        • may block menstrual flow

        • if incomplete, may cause dyspareunia (pain during intercourse) or obstruct vaginal delivery

Vulva (External Female Genitalia)

  • vulva

    • external structures that comprise the genitalia for females, collectively

  • mons pubis

    • pad of fat that is located on the anterior over pubic bone

    • becomes covered with hair in puberty

  • labia majora

    • folds of hair-covered skin that begin just posterior the mons pubis

  • labia minora

    • thinner and more pigmented

    • located on the inside of labia majora

  • clitoris

    • “glans clitoris”

    • encircled by the apex of the labia minora

    • originates from the same cells as the glans penis

    • has abundant nerves that make it important in sexual sensation, stimulation and orgasm

  • hymen

    • thin membrane located in the bottom portion of vagina

  • Bartholin’s glands

    • located on slightly inferior on either side of the vaginal introitus (opening)

    • secrete a fluid to lubricate the vagina

  • Skene’s glands

    • “lesser vestibular glands” or “paraurethral glands”

    • located on the anterior wall of vagina, near lower end of urethra

    • important in both urinary and sexual health

      • release fluids into the urethra to lubricate it

      • secrete mucous containing fluid when stimulated which helps lubricate vagina for intercourse

      • contain antimicrobial substances, which may help prevent UTI

      • sometimes referred to as female prostate

      • when aroused, there is increased blood flow resulting in swelling of Skene’s glands and clitoris

  • perineum

    • area between the legs, between the pubis symphysis and the anus

    • can be used for surgical access to vagina or rectum

Pregnancy

  • egg → zygote → blastocyst → gastrula → embryo → fetus →

  • zygote

    • travels to uterus and implants in uterine wall

    • divides by cleavage, to make more cells

    • does not grow in size

    • lasts 4 days

  • blastocyst

    • implants into endometrium and burrows into walls of uterus

  • embryo

    • lasts until week 8

  • fetus

    • organogenesis and formation of other germ layers takes place

  • placenta connects mother and fetus via umbilical cord

    • temporary organ

    • provides food and oxygen to the fetus and protects it, acting as barrier for infections experienced by mother

    • grows alongside fetus and is expelled after fetus is delivered

    • “after birth”

  • pregnancy is divided into 3periods

    • antepartum

      • conception → labor beginning

    • intrapartum

      • beginning of true labor → delivery of fetus

    • postpartum

      • delivery → 6 weeks

  • pregnancy is measured in weeks and has 3 trimesters

    • 1st trimester

      • upto 14 weeks

    • 2nd trimester

      • 14-28 weeks

    • 3rd trimester

      • 28-delivery

    • 37 weeks is considered full term, less than is pre-term

    • 40 weeks is considered normal gestation

    • 42+ weeks is considered post term

Gravidity and Parity

  • G_P_ or GTPAL

    • gravidity, term, preterm, abortion/miscarriage, live birth

  • gravidity

    • the number of pregnancies a woman has had

    • “G”

    • nulligravida

      • a woman who has never been pregnant

    • primigravida

      • a woman who is pregnant for the first time or who has been pregnant once

    • mutligravida or secundigravida

      • a woman who has been pregnant more than once

  • parity

    • the number of times a woman has given birth to a fetus more than 24 weeks gestation

    • can be live birth or not for parity count

    • “P”

Labor and Delivery

  • braxton hicks

    • practice contractions which feel very painful and real in the weeks leading up to the actual event

  • lightening

    • the sensation of feeling the fetus drop and head settle into pelvis

    • fetus not pressing on diaphragm anymore causes mothers to feel “lighter”

  • mucous plug

    • forms in cervix in early pregnancy to protect uterine opening

    • pushed into vagina when dilation begins in days leading to delivery

  • bloody show

    • increase in vaginal discharge that is clear, pink or slightly bloody

  • rupture of the membranes

    • when amniotic sac breaks

    • “water breaking”

    • a ferning test can determine if leaked fluid is amniotic

    • delivery should ideally occur within 24 hours to avoid amnionitis

      • serious in-womb infection

  • 6 stages of vaginal birth

    • prelabor

    • engagement (head in canal)

    • internal rotation

    • crowing (head showing)

    • extension of head (head out)

    • restitution (shoulders passing)

Abortion, Miscarriage

  • abortion

    • medically is the early loss of pregnancy

    • “spontaneous abortion”

      • miscarriage

      • causes bleeding, cramping, and expulsion of tissue

    • “missed abortion”

      • likely didn’t know they were pregnant

      • fetus stops developing and expires, retained inside uterus

      • surgical procedure used to remove fetus

    • “induced abortion”

      • intentional or deliberate termination of pregnancy for many reasons

Placental Problems    

  • placenta previa

    • when the placenta forms partially or completely toward the lower end of the uterus

    • sometimes will grow and move out of way

    • other cases require cesarean due to complete covering of the cervical os

  • placenta accreta

    • placenta digs too deep into uterine wall (without penetrating myometrium (uterine muscle) causing the placenta to not be expelled propely

    • leads to hemorrhage and shock

    • surgery needed to remove uterus is most cases

  • placenta increta

    • placenta develops in the uterine wall and penetrates myometrium (uterine muscle)

    • rare occurrence

    • usually requires cesarean section and subsequent hysterectomy

  • placenta pancreta

    • placenta latches all the way through uterine wall, maybe even growing on surrounding organs

    • extremely rare

    • requires cesarean section and subsequent hysterectomy

  • placental insufficiency

    • placenta unable to provide enough nourishment for fetus

    • has a variety of causes

    • treatments include better diet to medication

  • abruptio placenta

    • premature separation of placenta from uterine wall

    • obstetrical emergency

      • mother and fetus will hemorrhage to death

    • cesarean to deliver fetus and surgical intervention to stop in utero bleeding required

Ectopic and Pregnancy Loss

  • ectopic pregnancy

    • pregnancy occurring outside uterus

    • surgery may be necessary if body doesn’t naturally expel the tissue

  • blighted ovum

    • gestational sac that formed without an embryo within

  • molar pregnancy

    • hydatidiform mole

    • abnormal pregnancy with overgrowth of placenta and no viable fetus

    • surgery may be necessary if body doesn’t naturally expel the tissue

    • potentially becomes malignant, especially in cases where patient didn’t know they were pregnant

Common Conditions

  • gestational diabetes

    • diabetic symptoms caused by pregnancy

    • insulin receptors on cell membranes won’t let insulin in

    • usually resolves a few weeks after delivery

  • gestational hypertension

    • typically occurs during first pregnancy from 20 week mark to 6 weeks postpartum

    • can progress to preeclampsia or HELLP syndrome

      • hemolysis, elevated liver enzymes and low platelets syndrome

  • preeclampsia

    • formerly called toxemia

    • pregnancy-induced high blood pressure, accompanied by protein in the urine and swelling due to fluid retention

    • defined as new onset HTN of 140/90 after 20 weeks gestation

  • eclampsia

    • complication of preeclampsia

    • includes new onset of tonic-clonic (grand mal) seizure

  • toxoplasmosis

    • infection caused by single celled parasite (T. gondii) causing flu like symptoms including swollen lymph glands, muscle aches and pains (lasting days to weeks)

    • many people have had a toxoplasma infection but the immune system keeps parasite from causing illness

    • babies infected with toxoplasmosis before birth can be born with serious mental or physical problems

    • testing for antibodies or fetal testing including ultrasound and testing amniotic fluid or cord blood can be done

    • common ways to contract

      • food consumption

      • in many cases, while changing cat litter

  • chlamydia

    • most frequently reported bacterial infectious disease in the US

    • highest prevalence in 24 years and under

    • women experience multiple sequalae, including:

      • pelvic inflammatory disease (PID)

      • ectopic pregnancy

      • infertility

      • premature labor

      • rupture of the membranes

    • can be passed to fetus during birth causing eye inflammation or pneumonia in newborn

  • hepatitis

    • inflammation of the liver, which can cause cell damage and liver failur

    • most common cause of jaundice in pregnancy

    • most common forms are:

      • hepatitis A

        • single stranded RNA virus

        • most contracted through contact with contaminated feces or those with oral infections, also contracted through sexual contact

        • rarely transmitted intrauterine or perinatally

      • hepatitis B (HBV)

        • partially double stranded DNA virus

        • transmitted through intercourse, bodily fluid, blood transfusions

        • may be transmitted during childbirth

        • causing cirrhosis and hepatocellular carcinoma

      • hepatitis C (HCV)

        • partially doubled stranded plus-sense RNA virs

        • transmitted through parental transmission; IV drug users sharing needles, sexual contact and mother-to-child transmission

        • perinatal transmission is mostly during last month of pregnancy or delivery

        • risk for HCV increases with performing of invasive procedures (amniocentesis, chorionic villus sampling)

      • hepatitis D

        • caused by hepatitis delta virus (HDV)

        • single stranded, circular RNA virus

        • transmitted through the same routes as hep B

  • HIV/AIDS

    • human immunodeficiency virus (HIV)

    • kills or impairs the immune system and reduce the body’s ability to fight infections and certain cancers

    • mothers have a 1 in 4 chance of infecting their fetus if not on medication

    • advanced stage is acquired immunodeficiency syndrome (AIDS)

    • transmission:

      • sexual contact with infected partner or contact with infected blood

      • sharing needles, syringes and drug use equipement

      • maternal-fetal transmission during pregnancy, childbirth and breastfeeding (most cases reported is US)

  • genital herpes

    • caused by herpes simplex virus (HSV)

    • chronic infection with outbreaks

    • common signs and symptoms:

      • blisters and ulcers on the mouth

      • blisters and ulcers on the genital area

    • cesarean delivery for pregnant women with active infections as passage of the virus as fetus travels vaginal canal can cause blindness

Gynecological Conditions

  • endometriosis

    • when menstruation takes place, endometrium is not completely shed, and some tissue moves outside the uterus and reimplants (in places like the fallopian tube, ovaries, peritoneum, intestines or bladder)

    • this tissue follows the monthly cycle but as it as no exit route it is not expelled from body

    • untreated it usually causes infertility and the inability to sustain a pregnancy

    • symptoms:

      • extremely painful menstruation

      • bleeding between menstrual cycles

      • pelvic pain

  • adenomyosis

    • comparable to endometriosis except the endometrial tissue embeds itself deeper into the uterine muscle rather than escaping into the abdominal cavity

    • causes the uterus to enlarge with all the new tissue

    • responds to monthly cycle

    • symptoms:

      • severe pelvic pain

      • excessive bleeding

    • may respond to treatment but only cure is hysterectomy

  • genital prolapse

    • cystocele

      • happens when bladder falls into the vagina due to a weakness in the anterior vaginal wall

    • rectocele

      • happens when the rectum falls into vagina due to a weakness in the posterior vaginal wall

    • enterocele

      • happens when small intestine falls into the vagina due to weakness in the top apical portion of the vagina (the vaginal vault)

    • categorized by grade or degree of severity

    • treatments include insertion of pessary

      • pessary - prosthetic device that can be placed non-surgically in the vagina to support or lift prolapsed organs

      • if insufficient, surgical intervention may be needed

  • amenorrhea

    • loss of period

    • almost always related to another condition, including:

      • low body weight

      • excessive exercise

      • mental stress

      • eating problems

      • drugs and medications

      • pregnancy

      • hormonal imbalance

  • Bartholin’s gland cyst

    • exit from a gland gets backed up, forming these cysts

    • when cyst infected even walking can hurt

    • must be lanced, or opened and drained

  • cervical dysplasia

    • abnormal cells on a pap smear

  • dysmenorrhea

    • pain menstruation

  • dyspareunia

    • painful intercourse

  • leucorrhea

    • excessive white vaginal discharge

  • menopause

    • when menstrual cycle begins to cease

    • diagnosed 12 months after cycle stops

    • can occur anytime in 40s and 50s

    • ovaries making lower levels of estrogen, progesterone and testosterone

    • causes mood swings, hot flashes and difficulty sleeping

  • menorrhagia

    • abnormal uterine bleeding

    • heavier than normal

    • periods sometimes lasting more than 7 days

  • menometrorrhagia

    • excessive uterine bleeding, both during and between normal periods

    • longer lasting periods common

  • polycystic ovarian syndrome (PCOS)

    • hormonal disorder common among women of reproductive age

    • cause unknown

    • may cause irregular, prolonged periods

    • pt’s may have a higher level of male hormones called androgens

    • ovaries may develop several small follicles which may not mature properly to release eggs regularly

  • vaginitis

    • inflammation of the vagina the can result in discharge, itching and pain

    • etiology attributed to change in balance of vagina bacteria or infection

    • can be caused by reduced estrogen level in menopause or some skin conditions

    • most common types:

      • bacterial vaginosis

        • the result of an overgrowth of bacteria naturally found in vagina, which upsets balance

      • yeast infection

        • usually caused by naturally occurring fungus called candid albicans

      • trichomoniasis

        • caused by a parasite and is often sexually transmitted

  • fibroid tumors (myomas)

    • usually benign

    • tumors of the uterus

    • types:

      • intramural

        • within the walls of uterus

      • transmural

        • through the wall of the uterus

      • submucosal

        • reside just below the mucous lining and protrude into uterine cavity

      • subserosal

        • reside just below the serosal lining of uterus, (outer surface of uterus)

    • may cause excessive bleeding during mestruation and excessive pelvic pain, or affect fertility or ability to maintain pregnancy, pain during intercourse or chronic pressure felt in lower abdomen

    • can be treated symptomatically or with surgery

      • UAE

        • cutting into blood supply of fibroid to reduce size

Diagnostic Procedures

  • culdocentesis

    • procedure in which peritoneal fluid is obtained from the cul-de-sac of mother, using a spinal needle through the vaginal wall into the pouch of Douglas

    • finding blood during aspiration can indicate a ruptured ectopic pregnancy


  • dilatation and curettage (D&C)

    • cervix is dilated and the contents of the uterus is suctioned or scraped out using a a vacuum extractor or a sharp curette

    • common gynecological procedure

    • treats incomplete abortion or dysfunctional uterine bleeding

  • colposcopy

    • non-surgical procedure done to examine cervix, vagina and vulva more closely, usually following an abnormal pap smear

    • biopsy sample can be taken if anything concerning is found on the colposcope

  • hysteroscopy

    • procedure done to diagnose or treat uterine problems by using hysteroscope inserted through vagina to take pictures of uterus

    • sends pictures for further examination

    • might be used for:

      • removal of adhesions

      • locating an intrauterine device

      • determining cause of repeated miscarriage

  • hysterosalpingogram (HSG) or sonohysterography (saline sono)

    • done to evaluate the inside of the uterine cavity

    • HSG can also provide information regarding fallopian tubes

  • loop electrosurgical excision procedure (LEEP)

    • electrically charged, thin wire loop is inserted and used to cut away any abnormal tissue found on a pap smear

    • performed under local anesthesia

  • uterine biopsy

    • testing of endometrial tissue

    • method of evaluating:

      • uterine abnormalities

      • abnormal postmenopausal bleeding

      • presence of endometrial cancers or its precursors

    • done in an office with endometrial suction catheter

  • papanicolaou (Pap) test

    • collected cell specimens scraped from the cervix are examined under a microscope to check for abnormal, cancerous or pre-cancerous cells

    • can diagnose cervical intraepithelial neoplasia (CIN)

      • abnormal growth or premalignant cells

      • CIN grade I

        • mild dyslasia

        • “low-grade squamous intraepithelial lesion” (LGSIL)

      • CIN II

        • moderate dysplasia

      • CIN III

        • severe dysplasia

        • considered carcinoma in situ of cervix

        • “high-grade squamous intraepithelial lesion” (HGSIL)

  • human papillomavirus (HPV) test

    • sample from cervix is tested to determine whether HPV is present

    • HPV can lead to cervical cancer

      cold knife conization (cone biopsy)

      • removal of a cone or wedge of tissue from the cervix where abnormal cells were identified using pap smear

      • typically done in hospital

  • three hour GTT

    • follow up test for gestational diabetes performed after the mother has failed the initial glucose challenge test

    • done by drawing a sample of her initial fasting glucose level, then having her drink a special glucose-laden drink to draw the blood every hour for three hours to determine how her body is responding over time to the large surge of glucose

Hysterectomy Techniques

  • abdominal hysterectomy

    • uterus (or uterus and its adnexa) are removed through a 6-8 inch incision

    • reasons for procedure:

      • removal of ovaries and fallopian tubes

      • enlarged uterus

      • large fibroids

      • endometriosis, cancer or other diseases of the pelvic cavity

    • can either be vertical (laparotomy incision) or horizontal (Pfannenstiel incision) bikini cut (surgeon determines based on conditions)

  • vaginal hysterectomy

    • uterus is removed through vaginal opening

    • most often used when there is a vaginal prolapse or other vaginal repairs needed

    • not always possible due to size of removal contents

  • minimally invasive laparoscopic hysterectomy

    • the abdominal cavity is inflated with gas, and a laparoscope is used to remove the uterus through a tube or through the vagina

  • minimally invasive robotic hysterectomy

    • 3-d imaging is used to visualize the uterus as a surgeon uses a robotic device with miniature instruments to excise the uterus

  • colporrhaphy

    • surgical repair of a defect in the vaginal wall (like cystocele or rectocele)

    • performed through the vagina from anterior or posterior

      • anterior

        • used to treat a cystocele or urethrocele

      • posterior

        • used to fix a rectocele

    • accomplished by making incisions into the vaginal wall, and repairs are made in the fascia with sutures, removing any excess vaginal skin

Additional Vocab

  • cytogenetics - study of chromosome

  • erythematous - redness

  • external os - opening from cervix to vagina

  • fibroma - fibrous tumor

  • follicle - sac in ovary that contains an immature egg or oocyte

  • hydatidiform mole - a clump or mass of tissue that does not develop into a fetus

  • hypertrophic - increase in organ size due to enlargement of cells, not number of cells

  • inguinal adenopathy - swelling of lymph nodes in groin

  • introitus - vaginal opening

  • menarche - start of first period

  • missed abortion - loss of pregnancy before 20 weeks with retained tissue

  • oophorectomy - removal of one or both ovaries

  • perineum - area between the genitals and anus

  • salpingectomy - removal of fallopian tubes

  • spontaneous abortion - miscarriage

  • suprapubic - above pubic bone

Abbreviations

  • BC - birth control

  • BV - bacterial vaginosis

  • CIN - cervical intraepithelial neoplasia

  • CIS - carcinoma in situ

  • C/S - cesarean section

  • DNC - dilatation and curettage (D&C)

  • DUB - dysfunctional uterine bleeding

  • ECC - endocervical curettage

  • FLM - fetal lung maturity

  • HGSIL - high grade squamous intraepithelial lesion

  • HSG - hysterosalpingogram

  • hCG - human chorionic gonadotropin

  • IND - incision and drainage (I&D)

  • IVF - in vitro fertilization

  • LEEP - loop electrosurgical excision procedure

  • LGSIL - low grade squamous intraepithelial lesion

  • MLP - last menstrual period
    NST - nonstress test

  • PCOS - polycystic ovarian syndrome

  • PID - pelvic inflammatory disease

  • SROM - spontaneous rupture of membranes

  • TAH-BSO - total abdominal hysterectomy and bilateral salpingo-oophorectomy

  • TOLAC - trial of labor after cesarean section

  • VBAC - vaginal birth after cesarean

  • VIN - vulvar intraepithelial neoplasia