RK

Study Notes on the Diversity of Bacteria and Archaea

Diversity of Bacteria and Archaea

Prokaryotic Classification

  • Estimated Species: Roughly 1 million species of prokaryotes; only 6000 described and classified.

  • Taxonomy: The scientific study that organizes living organisms into groups, or taxa, based on shared characteristics.

    • Identification: Involves characterizing organisms to group them together.

    • Nomenclature: The system for naming organisms.

    • Classification: The arrangement of organisms into similar or related groups.

Strategies for Identifying Microorganisms

  • Microscopic Examination: Observing the organism's structure visually under a microscope to gain insights into its morphology.

  • Culture Characteristics: Analyzing how microorganisms grow in controlled environments such as petri dishes.

  • Biochemical Tests: Evaluating biochemical properties of microorganisms, such as fermentation patterns or enzyme presence.

  • Nucleic Acid Analysis: Using genetic information (DNA/RNA sequencing) for more precise identification.

  • Disease Symptoms: Relating specific microorganism presence to symptoms manifested in disease.

Phylogeny

  • Refers to the evolutionary relationships among organisms. Determining phylogenetic relationships is more complex in prokaryotes due to:

    • Asexual Reproduction: Limits the markers typically used for evolutionary relationships since genetic recombination is less frequent.

    • Few Differences in Cell Morphology: Many prokaryotes appear morphologically similar.

  • Sequencing Genes: Helps assist in classifying and identifying species based on genetic relatedness.

Remember Your Domains

  • Three Domains of Life:

    • Bacteria

    • Archaea

    • Eucarya

  • Subcategories of Bacteria:

    • Filamentous Anoxygenic Phototrophic bacteria

    • Gram-positive bacteria (e.g., Methanosarcina, Spirochetes)

    • Halobacteria, Proteobacteria, Thermococcus, etc.

Prokaryotic Diversity

  • Prokaryotes grouped based on distinctive characteristics include:

    • Lactic Acid Bacteria

    • Anoxygenic Phototrophs

    • Endospore Formers

    • Sulfide Reducers

  • Note: Groups with similar phenotypic and physiological traits may not share genetic relations.

Energy and Carbon Sources of Prokaryotes

TABLE 4.5: Energy and Carbon Sources Used by Different Groups of Prokaryotes

  • Types of Prokaryotes:

    • Photoautotroph

    • Energy Source: Sunlight

    • Carbon Source: CO₂

    • Photoheterotroph

    • Energy Source: Sunlight

    • Carbon Source: Organic compounds

    • Chemolithoautotroph

    • Energy Source: Inorganic chemicals (H$2$, NH$3$, NO$2$, Fe²⁺, H$2$S)

    • Carbon Source: CO₂

    • Chemoorganoheterotroph

    • Energy Source: Organic compounds (e.g., sugars, amino acids)

    • Carbon Source: Organic compounds

Evolution of Prokaryotes

  • Prokaryotes have existed for billions of years, gaining adaptations to various environmental conditions.

Anaerobic Chemotrophs

  • Early prokaryotic life existed in anoxic (no O₂) conditions for approximately 1.5 million years.

  • Current anaerobic environments include:

    • Soil

    • Aquatic environments

    • Human body (e.g., gastrointestinal tract)

  • Types of Organisms:

    • Anaerobic Chemolithotrophs

    • Anaerobic Chemoorganotrophs

Anaerobic Chemolithotrophs

  • Utilize Anaerobic Respiration:

    • Energy Source: Inorganic chemicals

    • Terminal Electron Acceptors: CO₂ and S.

  • Typically belong to Archaea (e.g., Methanogens):

    • Use H₂ gas and CO₂, releasing methane.

    • Habitats include sewage, swamps, marine sediments, and mammalian digestive tracts.

    • Highly sensitive to O₂.

Anaerobic Chemoorganotrophs

  • Obtain energy primarily through fermentation:

    • Genus Clostridium:

    • Characteristics: Gram-positive bacilli, produce endospores.

    • Noteworthy species and diseases:

      • C. tetani (Tetanus)

      • C. perfringens (Gas gangrene)

      • C. botulinum (Botulism)

Lactic Acid Bacteria

  • Classification: Typically Gram-positive, often obligate fermentors that produce lactic acid:

    • Genus Streptococcus:

    • Characteristics: Cocci that form chains, common normal microbiota.

      • S. pyogenes: Causes beta-hemolytic strep throat.

    • Genus Lactococcus: Known for use in the dairy industry.

    • Genus Enterococcus: Present in animal intestinal tracts.

    • Genus Lactobacillus: Forms chains or exists as single cells; common in normal flora, especially vaginal flora, and in food production.

Anoxygenic Phototrophs

  • Photosynthesis type that uses hydrogen sulfide or organic molecules as the electron source:

    • Unlike oxygenic phototrophs that use water and produce oxygen.

    • Found in aquatic habitats like bogs and upper layers of mud.

    • Includes purple and green sulfur bacteria.

Oxygenic Phototrophs

  • Photosynthetic bacteria using water as the source of electrons:

    • Cyanobacteria:

    • Earliest photosynthetic organisms, Gram-negative.

    • Habitat: Soil, rocks, freshwater, marine environments.

    • Capable of nitrogen fixation; exist as unicellular or multicellular forms.

    • Can cause blooms, releasing toxins.

Aerobic Chemoorganotrophs

  • Utilize organic compounds for energy, employing oxygen as their terminal electron acceptor.

  • Can be classified into:

    • Obligate Aerobes:

    • Exclusively use aerobic respiration. Example genera include:

      • Genus Micrococcus: Gram-positive cocci, found in soil. Produces pigmented colonies, such as M. luteus.

      • Genus Mycobacterium: Gram-positive, acid-fast bacilli (e.g., M. tuberculosis).

      • Genus Pseudomonas: Gram-negative, motile ang pigmented, often found in water (e.g., P. aeruginosa).

Facultative Anaerobes

  • Includes many members in the family Enterobacteriaceae (Enterics):

    • Gram-negative bacilli residing in the intestinal tract, many as normal microbiota.

    • Notable medically significant species include:

    • E. coli

    • Shigella species

    • Salmonella enteric strains (e.g., Salmonella typhi leading to typhoid fever).

    • Coliforms are common intestinal Enteric bacteria that can ferment lactose, often assessed as indicators of fecal pollution.

Survival in Terrestrial Environments

  • Prokaryotes such as those from Bacillus and Clostridium species can form resting stages to endure dry conditions:

    • Structures include endospores, cysts, fruiting bodies, and mycelium.

  • Endospores specifically exhibit high resistance to environmental insults compared to other resting structures.

Survival in Aquatic Environments

  • Prokaryotic organisms develop mechanisms for nutrient acquisition, including:

    • Forming chains encased in tubes to help locate favorable habitats. Notable genera include Sphaerotilus and Leptothrix.

Animals as Habitats for Bacteria

  • Animal bodies harbor diverse ecological niches:

    • Skin: Inhabited by Staphylococcus species, key components of skin flora.

    • Mucous Membranes: Home to genera such as Bacteroides, Bifidobacterium, Campylobacter, Helicobacter, Neisseria, and Treponema.

    • Intracellular parasites such as Rickettsia, Orientia, and Ehrlichia dwell within blood-sucking arthropods like ticks or lice.

Medically Important Bacteria

TABLE 11.3: Medically Important Bacteria

  • Gram-Negative Rods:

    • Includes genera such as Escherichia, Salmonella, Shigella, and Yersinia, often associated with significant diseases (e.g., E. coli causing UTIs).

  • Gram-Positive Rods:

    • Example: Bacillus anthracis (causing anthrax, used in bioterrorism).

  • Gram-Positive Cocci:

    • Includes Staphylococcus and Streptococcus genera, causing a range of infections from skin to systemic diseases.

Archaea Thriving in Extreme Conditions

  • Extreme Halophiles: Adapted to high-salt environments (e.g., salt lakes), requiring around 9% salt concentration. Includes Halobacterium and others.

Understanding Microbial Diversity

  • Microorganisms are diverse, existing in various habitats and conditions. Their metabolism must support survival, influencing their ecological roles positively.

How to Study This Material

  • Familiarize yourself with key terms related to microbial classification and identification.

  • Understand major groups discussed: Anaerobic chemotrophs, Anoxygenic phototrophs, Oxygenic phototrophs, Aerobic chemolithotrophs, and Chemoorganotrophs.

  • Begin familiarization with discussed microbes.

Discussion Questions

  • Soil Characteristics: Consider how Clostridium species' characteristics allow them to thrive in areas with drastic environmental changes.

  • Lake Ecosystem Changes: Discuss factors contributing to algal blooms in polluted waters, analyzing underlying water composition and remediation strategies.