Four Major Types:
Subtle Seizure:
Symptoms: sucking, blinking, pedaling of legs, eye deviation
Tonic Seizure:
Symptoms: extension of limbs, flexion of arms, extension of legs
Common in premature infants with intraventricular hemorrhage
Focal Clonic Seizure:
Symptoms: localized jerking
Can occur in term or premature infants
Myoclonic Seizure:
Symptoms: single or repetitive flexion jerks
Common Causes:
Hypoxic ischemic encephalopathy
Intracranial infections (e.g., meningitis)
Hypoglycemia
Metabolic disturbances
Epileptic syndromes
Intracranial hemorrhage
Developmental defects
Hypocalcemia
Normal Motor Activity:
Can be mistaken for seizures
Symptoms include myoclonic movements, dysconjugate eye movements, sucking movements
Importance of differential diagnosis
Overview:
Occurs secondary to perinatal asphyxia
Main cause of seizures in neonates
Typically manifests within the first 24 hours
Long-term developmental/cognitive delays possible
Motor impairments may develop over time
Basics:
Importance of balancing heat production and loss
Average normal temperature for newborns: 36.6 to 37.2°C
Heat Loss Implications:
Rapid heat loss can be life-threatening
Evaporation is the most significant source of heat loss
Core temperature can decrease rapidly
Non-shivering Thermogenesis:
Heat production through metabolism
Primary mechanism in neonates
Role of brown fat (thermogenic tissue unique to newborns):
Contains mitochondria, more capillaries
Stores around scapula, kidneys, adrenal glands, neck and axilla
Immediate Care Steps:
Dry newborn immediately after birth
Encourage skin-to-skin contact with parent; swaddle if needed
covering the heads and back (since the brown cells are stored around organs and areas near the back or the head)
Optimal room temperature: 23-24°C
Ensure environment is closed to minimize heat loss
Definition:
Rectal temperature greater than 38°C
Oral: 37.4°C; Axillary: 36.9°C
Concerns:
Neonates may exhibit hypothermia instead of fever
Potential for hypoglycemia and metabolic acidosis
Importance of identifying serious infections (e.g., UTI, meningitis, pneumonia)
Observation:
Monitor for rashes and vital signs
Remove extra clothing, improve ventilation
Assess last dose of fever management medication (e.g., acetaminophen, ibuprofen)
Definition:
Body temperature drop < 36°C
Risk Factors:
Higher risk in low birth weight infants
High sensitivity to environmental changes
Increased metabolic function can lead to hypoglycemia/hypoxemia
Symptoms:
NEONATES DO NOT SHIVER
Pale skin, cool to touch, acrocyanosis, respiratory distress, bradycardia
Initial irritability can progress to lethargy
Pre-hospital Care:
Ambulance temperature settings: 24-26°C
Dry and swaddled
rapid transport required
Definition:
Blood glucose < 2.6 mmol/l
Causes:
Limited glycogen stores (8-12 hours)
Often catastrophic for brain function; higher risks in specific populations (premature, low weight)
Typical Symptoms:
Cyanosis, irritability, apnea, poor feeding
Severe manifestations: lethargy, seizures, coma
Can also cause tachycardia, tachypnea, vomiting
Occurrence:
85% vomit in the first week, 10% by 6 weeks
Range from spitting up to projectile vomiting (fun…)
Clinical Implications:
Most episodes benign; however, persistent vomiting warrants attention
Blood presence may indicate serious conditions
Warning Signs of Severe Cases:
Poor general appearance
Vital sign abnormalities and extended capillary refill
Dry mucous membranes, weight loss, low urine output
Questions:
Encourage students to engage via discussion board or during synchronous sessions for further clarification on topics.