Chapter 10:
Depressants slow the central nervous system's activity, leading to relaxation and reduced inhibitions. This class of drugs can significantly affect judgment and coordination, and long-term use can lead to dependence. The three primary groups of depressants include:
Alcohol: Widely consumed worldwide with over 2 billion users; over half of U.S. adults drink occasionally. Sales in the U.S. exceed billions annually.
Sedative-hypnotic drugs: Initially barbiturates, now largely replaced by benzodiazepines due to their safety profile.
Opioids: Medications utilized for pain relief but carry a high risk of addiction.
Binge Drinking: Defined as consuming 5 or more drinks during a single occasion. Approximately 25% of U.S. adults binge drink at least monthly, while 6.5% are classified as heavy drinkers (5 or more times a month).
Demographics: heavy drinking is significantly more common in males versus females at a ratio of 2:1.
Effects of Ethyl Alcohol: Ethanol is quickly absorbed into the bloodstream, leading to its immediate effects on the central nervous system, particularly regarding the neurotransmitter GABA, which inhibits neural activity and induces relaxation.
Concentration Effects:
0.06%: Relaxed and comfortable
0.09%: Intoxication begins
0.55%: Risk of death
Metabolism: Alcohol can only be deactivated through metabolic processes, an average rate of approximately 25% of an ounce per hour.
Alcohol Use Disorder affects various demographics differently:
White Americans: 5.7%
Hispanic Americans: 5.3%
Black Americans: 4.5%
American Indians: 7.1% (highest prevalence)
Asians: 3.8% (many have a genetic aversion to alcohol due to a deficiency in alcohol dehydrogenase).
Treatment Options:
Aversion Therapy: Creates negative associations with alcohol consumption.
Cognitive Behavioral Therapy (CBT): Emphasizes planning and self-regulation to prevent relapses and patterns of drinking.
Alcoholism can lead to impairments in various cognitive functions, namely:
Memory and attention deficits
Speed of cognitive processing and reaction time.
Withdrawal from alcohol may yield severe psychological and physical symptoms:
Physical: Tremors, sweating, nausea, rapid heart rate.
Psychological: Increased anxiety and depressive symptoms may occur, leading to serious complications.
Delirium Tremens (DTs): A severe form of withdrawal that includes confusion, hallucinations, and seizures.
Alcoholism is implicated in 1/3rd of all suicides, homicides, assaults, and fatal accidents in the U.S.
It highly affects children of individuals with alcoholism, often leading to long-term issues of low self-esteem and marital problems.
Mechanism of Action: These drugs, also known as anxiolytics, produce calming effects, with low doses yielding relaxation and higher doses leading to sleep induction.
Historical Context: While barbiturates were once the go-to sedative, they have largely been replaced by benzodiazepines (e.g., Xanax, Ativan) due to a better safety profile.
Effects of Long-term Use: Chronic consumption can lead to dependence, impaired cognitive function, anxiety, and withdrawal symptoms upon cessation.
Opium Derivatives: Key drugs include heroin, morphine, and codeine, widely used for pain relief but consequently leading to high addiction potential.
Psychological Effects: Opioids attach to brain receptors for endorphins, producing significant pleasure and relaxation, which can lead users to prioritize drug use over basic needs.
Withdrawal Symptoms: Withdrawal can result in severe anxiety, muscle aches, nausea, and blood pressure spikes, severely impacting quality of life.
Epidemic Statistics: Opioid misuse has increased significantly, with recent data showing a rise in overdose deaths since COVID-19.
Main Types: Cocaine, amphetamines, and nicotine are primary stimulants, with widely varying effects and addiction potential.
Consequences of Misuse: Regular use may lead to stimulant use disorder, which dominates an individual's lifestyle and health.
Definition: Includes alcohol, cocaine, and gambling as significant focus areas in mental health and addiction discourse.
Identifying Characteristics: Involve problematic substance use leading to consequences across physical and mental health spectrums.
Consequences of Abuse: Relationships, employment, and day-to-day functioning become increasingly difficult due to substance-related behaviors.
CBT and Integrated Treatment: Incorporates both psychological and pharmacological strategies to treat substance use disorders effectively.
Importance of Community Support: Coordination among healthcare providers and community resources can significantly improve treatment outcomes.
Chapter 11:
Sexual Dysfunctions: Disorders that make it difficult or impossible to enjoy sexual intercourse, affecting 30% of men and 43% of women over their lifetimes.
Causes significant distress and interpersonal problems.
Phases of the Human Sexual Response Cycle:
Desire
Excitement
Orgasm
Resolution
Characteristics: Persistent lack of interest in sex; may experience normal sexual response when they do engage.
Checklist: For at least 6 months, few or no sexual thoughts, leading to significant distress.
Affects 10-15% of men globally, with increasing demand for therapy.
Overlap with Disorders: Considered one disorder due to overlap between desire and arousal in women.
Checklist: For at least 6 months, reduced or absent sexual interest, pleasure, and responses, leading to distress.
26-43% of women experience reduced sexual interest; significant distress qualifies for diagnosis.
Hormonal imbalances (elevated prolactin, low testosterone, estrogen fluctuations).
Certain medications, physical illnesses, and lifestyle factors may impair desire.
Increased anxiety, depression, or negative attitudes toward sex can lead to low desire.
Situational pressures (divorce, job stress) and relationship issues impact desire.
Trauma from sexual abuse can create aversion to sexual activity.
Definition: Persistent difficulty in achieving or maintaining an erection.
Checklist: For at least 6 months, difficulty with erectile function causing distress, affecting 16% of men worldwide.
Causes: Can stem from biological (vascular issues) or psychological factors (anxiety, relationship stress).
Definition: Ejaculation occurring within 1 minute of sexual activity, leading to distress.
Common in younger men, affecting a significant portion of the population.
Definition: Significant delay or absence of ejaculation during sexual activity for at least 6 months.
Affects 3-10% of men.
Characteristics: Persistent inability to achieve orgasm or very delayed orgasms for at least 6 months, leading to distress.
Affects about 21% of women, often linked to biological, psychological, and sociocultural factors.
Definition: Recurrent difficulties in vaginal penetration causing significant pain or fear.
Checklist: At least one of the following for 6 months: difficulty with penetration, significant pain, or muscle tension during intercourse.
Definition: Pain during intercourse without involuntary muscle contraction (14-16% of women).
Sex Therapy: Short-term, typically 15-20 sessions focusing on relationship dynamics, education, and sexual communication skills.
Incorporates CBT techniques and biological treatment options for various disorders.
Specific Treatments:
Erectile Disorder: Therapies emphasizing performance anxiety reduction, including medication like Viagra.
Premature Ejaculation: Behavioral techniques (stop-start method), SSRIs.
Female Orgasmic Disorder: CBT methods emphasizing body awareness and self-exploration, including directed masturbation training.
Genito-Pelvic Pain/Penetration Disorder: Behavioral therapy using gradual exposure and techniques to relieve muscle tension.
Focus on inclusivity and addressing the needs of diverse populations, including older adults, LGBTQ+ individuals, and those with disabilities.
Definition: Patterns of intense sexual urges or fantasies involving non-human objects or non-consenting partners.
Diagnosed only when they cause distress or impairment.
Characteristics: Sexual contact with children; often initiated by legal issues.
Checklist: Intense sexual urges or activities involving children for at least 6 months.
Characteristics: Sexual arousal from non-living objects or non-genital body parts. Common in men, often requires therapy for non-destructive coping.
Definition: Sexual arousal through dressing in clothing of a different gender, only a disorder if it causes distress.
Definition: Arousal from exposing one’s genitals to an unsuspecting person, generally begins in adolescence.
Therapeutic Options: Include cognitive-behavioral therapy, insight-oriented treatment, and sometimes pharmacological intervention (SSRIs, antiandrogens) to reduce sexual arousal.
Types and Causes: Characterized by long-term patterns of thoughts and behaviors. May involve genetic, psychological, and sociocultural factors. Biological and psychological treatments can be combined effectively.
Presents a spectrum of symptoms that often coalesce into distinctive features. It is believed to be multiple disorders with overlapping characteristics.
Characteristics: Excesses of thought, emotion, and behavior, including delusions and hallucinations.
Delusions: Firmly held false beliefs (persecution, reference, grandeur).
Disorganized Thinking: Tangential speech, loose associations may complicate communication.
Characteristics: Deficits of thought, emotion, and behavior, like lack of motivation and emotional flatness.
Symptoms include poverty of speech, social withdrawal, and blunted affect.
Cognitive Impairments: Difficulty with memory attention and processing, common in schizophrenia patients.
Psychomotor Symptoms: Abnormal movement patterns ranging from agitation to catatonia.
Typically emerges in late teens to mid-thirties with three phases:
Prodromal: Subtle changes and withdrawal.
Active Phase: Clear symptoms manifest.
Residual Phase: Symptoms decrease but some negative symptoms persist.
Genetic predisposition, neurotransmitter imbalances (particularly dopamine), and brain structure anomalies contribute to schizophrenia.
Historical theories suggest dysfunctional family environments or parenting styles may trigger symptoms in vulnerable individuals.
Antipsychotic Medications: Primarily dopamine antagonists, with both first and second-generation options available, offering relief from symptoms.
Psychotherapy: Cognitive-behavioral therapy, family interventions, and community-based approaches operate alongside pharmacological treatments to enhance functioning and reduce relapse risk.
Definition: Personality disorders involve long-standing patterns of thoughts and behaviors that deviate from cultural norms, causing distress and impaired functioning.
Types: Classified into three clusters based on shared characteristics.
Paranoid Personality Disorder: Characterized by pervasive distrust and suspicion of others, leading to social isolation.
Traits: Fear of harm, excessive trust in own beliefs, and reading hidden meanings into benign remarks.
Treatment: Limited effectiveness of therapy; some benefit from CBT.
Schizoid Personality Disorder: Characterized by a preference for solitude and lack of emotional expression.
Traits: Indifference to social relationships, limited emotional response, and preference for isolated jobs.
Treatment: Limited progress in therapy; CBT can help improve social interactions.
Schizotypal Personality Disorder: Features unusual thoughts, eccentric behavior, and discomfort in social relationships.
Traits: Odd speech patterns, magical thinking, and social anxiety.
Treatment: Therapy focuses on improving social skills and cognitive distortions. Medications may help with symptoms.
Antisocial Personality Disorder: Marked by patterns of manipulation and violation of others' rights; often associated with criminal behavior.
Traits: Lack of remorse, impulsivity, deceitfulness, and disregard for safety.
Treatment: Difficult due to lack of motivation for change; however, CBT may help individuals recognize moral issues.
Borderline Personality Disorder (BPD): Characterized by emotional instability, impulsive behaviors, and turbulent relationships.
Traits: Fear of abandonment, identity disturbances, and self-harming behaviors.
Treatment: Dialectical Behavior Therapy (DBT) is effective in reducing self-harm and improving emotional regulation.
Histrionic Personality Disorder: Excessive emotionality and attention-seeking behavior.
Traits: Constantly seeking approval, emotional outbursts, and dramatized expressions.
Treatment: CBT may help develop coping strategies and increase self-reliance.
Narcissistic Personality Disorder: Involves a pattern of grandiosity, need for admiration, and lack of empathy.
Traits: Belief in superiority, entitlement, and sensitivity to criticism.
Treatment: Difficult due to the tendency to dismiss weaknesses; psychodynamic therapy may help patients confront underlying insecurities.
Avoidant Personality Disorder: Characterized by social inhibition and feelings of inadequacy.
Traits: Sensitivity to negative evaluation, fear of rejection, and chronic feelings of inferiority.
Treatment: CBT aimed at improving social skills and addressing fears of criticism; may benefit from exposure therapy.
Dependent Personality Disorder: Involves excessive need to be taken care of, leading to submissiveness and clinging behaviors.
Traits: Difficulty making decisions without advice, fear of separation, and reliance on others for emotional support.
Treatment: CBT can help build independence and challenge feelings of helplessness.
Obsessive-Compulsive Personality Disorder (OCPD): Characterized by a preoccupation with orderliness, perfectionism, and control.
Traits: Rigidity, stubbornness, and reluctance to delegate tasks.
Treatment: Psychodynamic therapy and CBT can help individuals recognize and adjust their inflexibility and obsessive traits.
Diagnostic Considerations: Diagnosis should not be made until after age 18, as traits can develop and change during adolescence.
Current Research: Emphasizes the need for a dimensional approach to personality traits and their impact on functioning. The DSM-5 includes trait-specified personality disorders for individuals exhibiting significant impairment due to problematic traits.
Trait Categories:
Negative Affectivity: Emotional instability and anxiety.
Detachment: Social withdrawal and anhedonia.
Antagonism: Hostility and deceitfulness.
Disinhibition: Impulsivity and irresponsibility.
Psychoticism: Unusual beliefs and eccentric behaviors.
Understanding personality disorders is crucial for more effective treatment approaches.
Therapists need to tailor interventions to the individual’s specific traits and behaviors for optimal outcomes.