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Module 12: Obesity and Lipid Storage Diseases

Obesity - It is a body condition characterized by the excessive accumulation of fat in the body, particularly in the adipose tissues beneath the skin and within other organs, including muscles.

Obese - A person can be categorized if he/she is overweight or has an abnormal increase in body weight beyond that is considered desirable with regards to age, height and bone structure.

Atherosclerosis – a form of Arteriosclerosis (“hardening of the arteries”) due to the formation of abnormal masses of fatty or lipid material (atheroma) within the intima or inside the lumen of arteries resulting to obstruction to the blood supply and eventual dysfunction of these blood vessels

Hypertension – persistently high pressure of the blood against the arterial walls

Myocardial infarction – commonly referred to as “heart attack”, it refers to the death or necrosis of the cells of an area of the heart muscle (myocardium) as a result of oxygen deprivation due to blood supply obstruction which can lead to death

Respiratory problems like shortness of breath that can lead to easy tiredness or exhaustion of the body thus can result to a deprived capacity or even the inability to be involved in physical activities like sports.

Diabetes mellitus (type II) – due to a decreased sensitivity of the body tissues to insulin

Osteoarthritis – frequent sensation of chronic back and joint pains from increased strain on joints and ligaments

Diaphoresis – excessive or profuse secretion of sweat

Halitosis – offensive odor of the breath due to rancidity of fats in the throat

Vaginal candidiasis (for obese females) and body odor – since a fatty environment can be accessible to culture microorganisms like fungi and bacteria

Amenorrhea (secondary) – absence of the onset of menstruation which may lead to sterility

Lipemia retinalis – manifestation of a milky appearance of the blood vessels due to excess fat in the blood which can result to blurredness of sight and eventual blindness

Lipomatosis / Liposis – condition characterized by abnormal localized or tumor – like accumulations of fat in the tissues

Immunosusceptibility – increased physical defenselessness or a greater tendency to contract infectious diseases

Intestinal bypass (Jejunoileal shunt) – the proximal jejunum and terminal ileum are bypassed in order to bring about malabsorption of digested food.

Jejunoileal shunt – other name for Intestinal bypass

Liposuction – aspiration of excess fat usually in the subcutaneous tissues

to help treat pain (including bone pain) for patients with Fabry disease - The drugs phenytoin and carbamazepine may be prescribed

Lipid storage diseases - are a group of inherited metabolic disorders in which harmful amounts of fatty materials called lipids accumulate in some of the body’s cells and tissues.

Lipidoses – other name for Lipid storage diseases

to help treat pain (including bone pain) for patients with Fabry disease - The drugs phenytoin and carbamazepine may be prescribed

Module 12: Obesity and Lipid Storage Diseases

Obesity - It is a body condition characterized by the excessive accumulation of fat in the body, particularly in the adipose tissues beneath the skin and within other organs, including muscles.

Obese - A person can be categorized if he/she is overweight or has an abnormal increase in body weight beyond that is considered desirable with regards to age, height and bone structure.

Atherosclerosis – a form of Arteriosclerosis (“hardening of the arteries”) due to the formation of abnormal masses of fatty or lipid material (atheroma) within the intima or inside the lumen of arteries resulting to obstruction to the blood supply and eventual dysfunction of these blood vessels

Hypertension – persistently high pressure of the blood against the arterial walls

Myocardial infarction – commonly referred to as “heart attack”, it refers to the death or necrosis of the cells of an area of the heart muscle (myocardium) as a result of oxygen deprivation due to blood supply obstruction which can lead to death

Respiratory problems like shortness of breath that can lead to easy tiredness or exhaustion of the body thus can result to a deprived capacity or even the inability to be involved in physical activities like sports.

Diabetes mellitus (type II) – due to a decreased sensitivity of the body tissues to insulin

Osteoarthritis – frequent sensation of chronic back and joint pains from increased strain on joints and ligaments

Diaphoresis – excessive or profuse secretion of sweat

Halitosis – offensive odor of the breath due to rancidity of fats in the throat

Vaginal candidiasis (for obese females) and body odor – since a fatty environment can be accessible to culture microorganisms like fungi and bacteria

Amenorrhea (secondary) – absence of the onset of menstruation which may lead to sterility

Lipemia retinalis – manifestation of a milky appearance of the blood vessels due to excess fat in the blood which can result to blurredness of sight and eventual blindness

Lipomatosis / Liposis – condition characterized by abnormal localized or tumor – like accumulations of fat in the tissues

Immunosusceptibility – increased physical defenselessness or a greater tendency to contract infectious diseases

Intestinal bypass (Jejunoileal shunt) – the proximal jejunum and terminal ileum are bypassed in order to bring about malabsorption of digested food.

Jejunoileal shunt – other name for Intestinal bypass

Liposuction – aspiration of excess fat usually in the subcutaneous tissues

to help treat pain (including bone pain) for patients with Fabry disease - The drugs phenytoin and carbamazepine may be prescribed

Lipid storage diseases - are a group of inherited metabolic disorders in which harmful amounts of fatty materials called lipids accumulate in some of the body’s cells and tissues.

Lipidoses – other name for Lipid storage diseases

to help treat pain (including bone pain) for patients with Fabry disease - The drugs phenytoin and carbamazepine may be prescribed