PNEUMOTHORAX - Chapter 23 (RC122 Respiratory Care Pathophysiology)
Pneumothorax - Comprehensive Study Notes (Chapter 23)
Pneumothorax: General Concepts
- Definition: A pneumothorax exists when gas accumulates in the pleural space, causing separation of the visceral and parietal pleura.
- Key signs of pneumothorax:
- Hyperresonance on percussion on the affected side
- Decreased or absent breath sounds over the pneumothorax
- Tracheal deviation can occur in tension pneumothorax (away from the affected side)
- Pleural air may cause chest pain and dyspnea
- Pendelluft phenomenon: Paradoxical movement of air within the lungs/chest wall contributing to altered ventilation; linked to chest wall and lung dynamics (referenced with Flail Chest discussion)
- Initial emergency intervention (for tension/open pneumothorax): Needle decompression in the 2nd intercostal space at the midclavicular line, followed by chest tube thoracostomy
- Important clinical target: Restore lung expansion and prevent air entry or re-entry into the pleural space
Pneumothorax Classifications
- General terms:
- Closed pneumothorax: Gas in pleural space is not in direct contact with the atmosphere
- Open pneumothorax: Pleural space is in direct contact with the atmosphere; gas can move in and out
- Tension pneumothorax: A one-way valve effect of ruptured parietal pleura; gas enters during inspiration but cannot exit during expiration; most dangerous form
- Based on origin:
- Traumatic pneumothorax: Caused by penetrating wounds (knife, bullet, impaling object)
- Spontaneous pneumothorax: Occurs without an underlying cause; can be secondary to pneumonia, TB, COPD (blebs/bullae on lung surface can rupture); more common in tall, thin individuals aged roughly 15–35 years
- Iatrogenic pneumothorax: Occurs during diagnostic or therapeutic procedures
Iatrogenic Pneumothorax (examples)
- Pleural or liver biopsy
- Thoracentesis
- Intercostal nerve block
- Cannulation of a subclavian vein
- Tracheostomy (perforation of the posterior tracheal wall can lead to pneumomediastinum)
- Excessive pressure during mechanical ventilation can cause a pneumothorax
- Cannot be caused by an endotracheal tube (ET tube) per se
- Figure 22-1: Right-side pneumothorax with GA (gas accumulation) and CL (collapsed lung); inset shows atelectasis as a common secondary change
- Figure 22-2: Sucking chest wound with an open pneumothorax due to traumatic injury
- Figure 22-3: Closed (tension) pneumothorax produced by chest wall injury
- Figure 22-4: Right pneumothorax caused by visceral pleural rupture acting as a check valve; progressive enlargement with ipsilateral atelectasis
Pneumothorax Anatomical and Pathophysiological Alterations
- Lung collapse
- Atelectasis
- Asymmetrical chest wall expansion
- Compression of the great veins and decreased venous return to the heart
- General consequence: impairment of gas exchange and hemodynamics
Pneumothorax Classifications (Summary)
- Closed vs Open vs Tension; based on contact with atmosphere and one-way valve mechanism
- Based on origin: Traumatic, Spontaneous, Iatrogenic
Clinical Manifestations
- Systemic responses:
- Increased respiratory rate (RR) due to stimulation of peripheral chemoreceptors
- Tachycardia (increased HR) and elevated blood pressure (BP)
- Hypoxemia
- Pain and anxiety
- Cyanosis in more severe cases
- Chest findings:
- Hyperresonance to percussion on affected side
- Diminished or absent breath sounds over the affected hemithorax
- Tracheal shift away from the affected side in tension pneumothorax
- Possible displacement of heart sounds
- Pendelluft: paradoxical movement of air between lung regions during respiration; contributes to uneven ventilation
Venous Admixture and V/Q Effects
- Pendelluft leads to lung collapse and atelectasis, decreasing the V/Q ratio (reduced alveolar ventilation)
- Resultant intrapulmonary shunting and venous admixture worsen oxygenation
- PaO2 decreases and peripheral chemoreceptors may be stimulated to increase ventilatory rate
Pulmonary Function Test Findings (PFT)
- Pattern: Moderate to severe restrictive lung physiology indicated
- Lung volumes and capacities affected:
- VT (tidal volume)
- IRV (inspiratory reserve volume)
- ERV (expiratory reserve volume)
- RV (residual volume)
- VC (vital capacity)
- IC (inspiratory capacity)
- FRC (functional residual capacity)
- TLC (total lung capacity)
- RV/TLC ratio
- Overall: reductions across the above parameters consistent with restrictive physiology
Arterial Blood Gases (ABG) – Small Pneumothorax
- Pattern: Acute alveolar hyperventilation with hypoxemia (acute respiratory alkalosis)
- Expected trends:
- pH: ↑ (alkalosis)
- PaCO2: ↓
- HCO3-: approximately normal
- PaO2: ↓
- SaO2/SpO2: may be reduced or variable
Arterial Blood Gases (ABG) – Large Pneumothorax
- Pattern: Acute ventilatory failure with hypoxemia (acute respiratory acidosis)
- Expected trends:
- pH: ↓
- PaCO2: ↑
- HCO3-: ↑ (metabolic compensation over time may occur)
- PaO2: ↓
- SaO2/SpO2: ↓
Pneumothorax on Chest X-ray (CXR)
- Increased translucency (lucency) on the side of the pneumothorax
- In tension pneumothorax: mediastinal shift away from the affected side
- Depressed diaphragm on the affected side
- Associated atelectasis
Case Visuals and Scenarios
- Figure 22-9 (A and B): Small tension pneumothorax developing in the lower right lung; subsequent mediastinal and cardiac shift with progression
- Figure 22-10 (A and B): Tall, slender patient with spontaneous left pneumothorax; radiographs show heart mediastinal shift toward the unaffected side as the tension pneumothorax evolves
Pneumothorax – Treatment Thresholds and Options
- If lung collapse is 15% to 20%: bed rest or limited physical activity; intrapleural gas resorption usually within 30 ext{ days}
- If lung collapse is > 20%: chest tube insertion (thoracostomy) to evacuate air or needle aspiration
- Pleurodesis: chemical-induced inflammatory reaction between lung surface and inner chest wall to cause lung to adhere to chest cavity; reduces recurrence risk
- Oxygen therapy
- Lung expansion therapy
- Mechanical ventilation when indicated
Thoracostomy (Chest Tube Insertion) – Procedure and Management
- Purpose: Create an opening in the chest wall to place a chest tube (thoracic catheter) to allow air and fluid to escape the chest
- Chest tube is attached to an underwater seal to prevent air re-entry (entrainment) into the lung
- Suction may be applied; when used, negative pressure should be limited to -12 ext{ cmH}2 ext{O}; -5 ext{ cmH}2 ext{O} is often sufficient
- After lung re-expansion and cessation of bubbling, leave the tube in place without suction for an additional 24–48 hours
Underwater Seal System (With Chest Tube)
- Diagrammatic description:
- From patient -> water seal bottle -> open to air
- Water level in the seal (typically around 2 ext{ cm}) provides a barrier to entrainment
- When the patient inspires, the water seal prevents room air from entering the pleural space
Chest Tube – Post-Placement Imaging
- Chest X-ray confirms tube positioning and lung re-expansion
Pleurodesis (Therapeutic Adherence of Pleura)
- Talc pleurodesis: Talc is applied between the visceral and parietal pleura
- Mechanism: Talc induces inflammation and adhesions, sealing the pleural space and preventing recurrent pneumothorax
- Indicated for recurrent spontaneous pneumothorax or persistent air leaks
Quick Reference – Key Numerical Values (summary)
- Needle decompression site: 2nd intercostal space at the midclavicular line
- Chest tube suction limits: -12 ext{ cmH}2 ext{O} (maximum) or -5 ext{ cmH}2 ext{O} (commonly sufficient)
- Pleural space management thresholds: 15–20% collapse (conservative management) vs >20% collapse (drainage required)
- Pleurodesis agent: talc (as described)
- Water seal level in underwater seal: approximately 2 ext{ cm}
- Time to resorption for small pneumothorax: about 30 ext{ days}
- Common etiologies: Traumatic, Spontaneous (often in tall/thin individuals aged 15–35 ext{ years}), Iatrogenic
Connections to Practice and Real-World Relevance
- Recognition of tension pneumothorax requires rapid assessment for tracheal deviation, hypotension, tachycardia, and respiratory distress; immediate decompression is life-saving
- Differentiating between spontaneous, traumatic, and iatrogenic pneumothorax guides management and prevention of recurrence
- Understanding pleurodesis helps prevent recurrent pneumothorax in patients with high risk
- Imaging (CXR) findings guide timing of pleural drainage and monitor progression
Ethical, Philosophical, and Practical Implications
- Rapid, decisive intervention can be life-saving in tension pneumothorax, highlighting the balance between emergent care and definitive treatment
- Invasive procedures (chest tubes, pleurodesis) carry risks; patient consent and discussion of recurrence risk and alternatives are important
- Resource utilization considerations: decisions between observation vs intervention based on percentage collapse and clinical stability