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Post-Traumatic Stress Disorder

Clinical Description

  • Trauma exposure

  • Continued re-experiencing

    • (e.g., memories, nightmares, flashbacks)

  • Avoidance

  • Emotional numbing

  • Reckless or self-destructive behavior

  • Interpersonal problems

  • Refers to problems that persist for more than one month after the trauma

    • Acute stress disorder assigned for posttraumatic symptoms lasting less than a month

  • Statistics

    • 6.8% (life); 3.5% (year)

    • Prevalence varies

      • Most people who undergo traumatic events do not develop PTSD

      • Type of trauma

        • E.g., experiencing repeated sexual assault makes an individual 2 to 3 times as likely to develop PTSD

      • Proximity – more likely to develop PTSD if closer to the trauma

Causes of PTSD

  • Trauma intensity – PTSD more likely with severe trauma

  • Generalized biological vulnerability

    • Twin studies

    • Reciprocal gene-environment interactions

  • Generalized psychological vulnerability

    • Beliefs about uncontrollability and unpredictability of threatening situations

  • Poor social support = greater risk

Diagnostic Criteria

  • Exposure to actual or threatened event

  • Presence of one or more intrusional symptoms

  • Persistent avoidance of stimuli associated with traumatic event

  • Negative alterations in cognitions and mood associated with traumatic event

  • Marked alterations in arousal and activity associated with the traumatic event

  • Sleep disturbance

  • Significant distress

  • Not attributable to substance use

Neurobiological Model

  • Threatening cues activate CRF system

  • CRF system activates fear and anxiety areas

    • Amygdala (central nucleus)

  • Increased HPA axis activation

    • Cortisol

Treatment

  • Cognitive-behavioral treatment

    • Imaginal exposure to memories of traumatic event

    • Graduated or massed

    • Increase positive coping skills

    • Increase social support

    • Highly effective

  • Psychoanalytic therapy: catharsis = reliving emotional trauma to relieve suffering

  • Medications

    • SSRIs can be helpful

      • Relieve heightened anxiety and panic attacks common to PTSD

Post-Traumatic Stress Disorder

Clinical Description

  • Trauma exposure

  • Continued re-experiencing

    • (e.g., memories, nightmares, flashbacks)

  • Avoidance

  • Emotional numbing

  • Reckless or self-destructive behavior

  • Interpersonal problems

  • Refers to problems that persist for more than one month after the trauma

    • Acute stress disorder assigned for posttraumatic symptoms lasting less than a month

  • Statistics

    • 6.8% (life); 3.5% (year)

    • Prevalence varies

      • Most people who undergo traumatic events do not develop PTSD

      • Type of trauma

        • E.g., experiencing repeated sexual assault makes an individual 2 to 3 times as likely to develop PTSD

      • Proximity – more likely to develop PTSD if closer to the trauma

Causes of PTSD

  • Trauma intensity – PTSD more likely with severe trauma

  • Generalized biological vulnerability

    • Twin studies

    • Reciprocal gene-environment interactions

  • Generalized psychological vulnerability

    • Beliefs about uncontrollability and unpredictability of threatening situations

  • Poor social support = greater risk

Diagnostic Criteria

  • Exposure to actual or threatened event

  • Presence of one or more intrusional symptoms

  • Persistent avoidance of stimuli associated with traumatic event

  • Negative alterations in cognitions and mood associated with traumatic event

  • Marked alterations in arousal and activity associated with the traumatic event

  • Sleep disturbance

  • Significant distress

  • Not attributable to substance use

Neurobiological Model

  • Threatening cues activate CRF system

  • CRF system activates fear and anxiety areas

    • Amygdala (central nucleus)

  • Increased HPA axis activation

    • Cortisol

Treatment

  • Cognitive-behavioral treatment

    • Imaginal exposure to memories of traumatic event

    • Graduated or massed

    • Increase positive coping skills

    • Increase social support

    • Highly effective

  • Psychoanalytic therapy: catharsis = reliving emotional trauma to relieve suffering

  • Medications

    • SSRIs can be helpful

      • Relieve heightened anxiety and panic attacks common to PTSD

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