Delinquent Peer Group Formation: Evidence of a Gene × Environment Correlation

Abstract

  • Emergence of biosocial explanations for adolescent development. Variants of specific genes may influence youths to seek out or associate with antisocial peers.

  • Study uses genotypic data (N = 1,816) from Add Health to test whether the dopamine transporter gene DAT1 (particularly the 10R allele) is associated with delinquent peer affiliation.

  • Key finding: The 10R allele of DAT1 is associated with higher self-reported delinquent peer affiliation for male adolescents from high-risk environments, even after controlling for delinquent involvement, self-control, and drug/alcohol use. β-range for this effect: eta ext{ in } [0.13, 0.14].

  • Implication: Supports a biosocial, gene × environment correlation (rGE) framework for adolescent peer selection and antisocial development.

Key Concepts and Definitions

  • Homophily (Birds of a feather): tendency to associate with similar others (talents, beliefs, behaviors).

    • Evidence: associations by race/ethnicity, age/education, etc. (Giordano 2003; McPherson et al. 2001; others).

  • Delinquent peers: peers engaged in delinquency, drug use, and related antisocial behaviors; strong predictor of antisocial conduct.

    • Warr (2002) and Warr (1998, 2002) emphasize persistent link between delinquent peers and misconduct.

  • Gene × Environment Correlation (rGE): when an individual’s genotype is partially responsible for shaping the environment they experience.

    • Types of rGE:

    • Passive rGE: parents pass on genes and provide environment correlated with those genes.

    • Evocative rGE: an individual’s genetically influenced traits evoke specific responses from the environment.

    • Active rGE: individuals select environments compatible with their genotypes.

    • References: Caspi & Moffitt (1995); Scarr & McCartney (1983); Rutter (2006); Walsh (2002).

  • DAT1 (Dopamine transporter gene): genetic polymorphism with 40-base pair VNTR in the 3'-UTR, typically 9R or 10R alleles.

    • The 10R allele is considered the risk allele, associated with ADHD, externalizing problems, and related maladaptations (Comings et al. 2001; Rowe et al. 1998; Gill et al. 1997).

    • Genotype coding in Add Health: number of 10R alleles, values 0, 1, or 2 (0 = no 10R alleles, 1 = one, 2 = two).

  • Add Health (NSDUH Add Health): nationally representative longitudinal study of adolescents in grades 7–12 with genetic data available at Wave III.

    • Final analytic sample for this study: N = 1{,}816 (after removing one twin from each MZ pair and after data cleaning).

  • Family risk composites: combining maternal attachment, maternal involvement, and maternal disengagement into a single family risk factor; dichotomized into low (0) vs high (1) risk groups.

  • Delinquent peers measure: three-item scale at Wave 1 assessing friends’ smoking, drinking, and marijuana use; responses summed and standardized (α = .76).

  • Control variables: age, paternal criminal history, delinquency, low self-control, and drug/alcohol use.

Theoretical Background: Why rGE Matters for Delinquent Peers

  • Traditional debate: social causation (peers cause delinquent behavior) vs self-selection (individual differences lead to selection of delinquent peers).

  • Walsh (2002) highlights that people seek environments compatible with their genetic dispositions; this motivates testing for rGE in delinquent peer networks.

  • rGE provides a mechanism by which genotype may influence exposure to antisocial environments, potentially explaining part of the association between genes and delinquent outcomes.

  • Prior genetic research on peer context (Iervolino et al. 2002; Cleveland et al. 2005; Kendler et al. 2007) suggests genetic contributions to exposure to antisocial peers, though findings are mixed across samples and designs.

Present Study: DAT1 and Delinquent Peer Selection

  • Research question: Is there a gene × environment correlation between the DAT1 gene and assortative formation into delinquent peer networks?

  • Data source: Add Health Wave III genetic subsample (N = 1,816 after data cleaning).

  • Hypothesis: DAT1 variation, particularly the 10R allele, would be associated with delinquent peer affiliation, especially among males in high-risk family environments.

  • Rationale: Active rGE predicts that youths with certain genotypes may actively select into environments that maximize gene expression (e.g., antisocial peer groups).

  • Context: Previous research shows rGEs in other domains (ADHD, externalizing problems, substance use) and suggests gene × environment interplay in social contexts.

Methods

Sample and Genotyping

  • Add Health Wave III: includes genetic data; final analytic sample: N = 1{,}816.

  • Genotyped DAT1 locus focused on 40-bp VNTR with alleles 9R and 10R.

  • Allele distribution in this sample:

    • 0 copies of 10R: 5.3 ext{%},

    • 1 copy: 35.1 ext{%},

    • 2 copies: 59.6 ext{%}.

  • Hardy–Weinberg equilibrium: χ²(1, N = 1,816) = 0.0239, p > .05.

  • DAT1 variable recoded as ext{DAT1}_{10R} o ext{0,1,2}, representing the number of 10R alleles.

    • Coding: 0 = no 10R alleles, 1 = one 10R allele, 2 = two 10R alleles.

Measures

  • Delinquent peers (Wave 1): three items indicating whether close friends smoke ≥1 cigarette/day, drink alcohol once a month, or smoke marijuana ≥ once a month.

    • Scale: sum of three items; transformed to a standardized scale (higher values = more involvement with antisocial friends).

    • Reliability: ext{α} = .76.

  • DAT1: as described above (0, 1, 2 copies of 10R).

  • Family risk (Wave 1): three scales combined via factor analysis, then dichotomized at the mean into low-risk (0) vs high-risk (1) family environments.

    • Maternal attachment: two items; higher scores indicate less attachment after recoding (α = .64).

    • Maternal involvement: 10 activities with mother; coded 1 if engaged in activity, 0 otherwise (α = .55).

    • Maternal disengagement: five items indicating perceived maternal coldness/withdrawal (α = .84).

    • Result: a single factor captures global family risk; dichotomized as described.

  • Control variables:

    • Age (years at Wave 1).

    • Criminal father: whether the respondent’s biological father was ever incarcerated (dichotomous).

    • Delinquency: Wave 1 delinquency scale (15 items; 0,1,2,3 coding; α = .78).

    • Low self-control: five-item scale (α = .63).

    • Drug and alcohol use: composite of alcohol use and marijuana use in the past 12 months (Wave 1).

Analytic Strategy

  • Primary approach: Ordinary Least Squares (OLS) regression to predict delinquent peers from DAT1 while controlling for covariates.

  • Stratified analyses by gender and by race (non-Hispanic White and Black) to assess potential differential DAT1 effects.

  • Subgroup analyses by family risk level (low vs high) to test for moderation by environment.

  • Additional spuriousness checks: include delinquency, low self-control, and drug/alcohol use to test whether the DAT1 effect persists when controlling for related antisocial traits and tendencies.

  • Note on sample size: high-risk male subsample used for some robustness checks to preserve degrees of freedom (n ≈ 341 in Table 3 analyses).

Results: Direct Effects of DAT1 on Delinquent Peers

  • Overall model characteristics (Table 1, full sample and subgroups):

    • Full sample (N = 1,816):

    • DAT1: b = 0.05, ext{ } eta = 0.03, ext{ } SE = 0.04, ext{ } R^2 = 0.09, not significant overall.

    • Male adolescents (n = 849):

    • DAT1: b = 0.17, ext{ } eta = 0.10^{*}, ext{ } SE = 0.06, ext{ } R^2 = 0.10.

    • Age: b = 0.18, ext{ } eta = 0.29^{*}, ext{ } SE = 0.01.

    • Criminal father: b = 0.18, ext{ } eta = 0.07^{*}, ext{ } SE = 0.07.

    • Note: asterisk indicates p < .05.

    • Female adolescents (n = 967):

    • DAT1: b = -0.06, ext{ } eta = -0.03, ext{ } SE = 0.04, ext{ } R^2 = 0.09.

    • White adolescents (n = 1,464):

    • DAT1: b = 0.05, ext{ } eta = 0.03, ext{ } SE = 0.04, ext{ } R^2 = 0.09.

    • Black adolescents (n = 352):

    • DAT1: b = 0.12, ext{ } eta = 0.07, ext{ } SE = 0.09, ext{ } R^2 = 0.07.$

  • Key takeaway from Table 1: DAT1 is predictive of delinquent peers only for the subsample of male adolescents; for females and for most race groups, the direct DAT1 effect is non-significant in the full models.

  • Gender-specific interpretation: The DAT1 effect on delinquent peers is present for males (β ≈ .10; p < .05) but not for females.

Mediation/Moderation: DAT1 by Family Risk (Table 2)

  • Researchers tested whether the DAT1 effect is conditioned by family risk level (low vs high).

  • Findings for male adolescents (White and Black; combined) show:

    • Low-risk families (n for White and Black combined): age is the main predictor; DAT1 effect not significant.

    • High-risk families (n for White and Black combined): DAT1 is significantly related to delinquent peers across the models, indicating a robust gene × environment interaction for DA transporters in adverse family contexts.

  • Overall interpretation: For male adolescents, the DAT1 × family-risk interaction suggests that the genetic propensity (10R allele) to affiliate with delinquent peers is amplified in high-risk environments and attenuated or null in low-risk environments.

Robustness Checks: Spuriousness Tests (Table 3)

  • High-risk male adolescents (N ≈ 341) tested to ensure DAT1’s association with delinquent peers is not due to confounding by delinquency, self-control, or drug/alcohol use.

  • Model specifications incorporated additional controls (Delinquency, Low Self-Control, Drug/Alcohol use) in various combinations (Models 1–4):

    • DAT1 coefficients remain significant and positive across all four models when predicting delinquent peers in high-risk males.

    • Coefficients for DAT1 ranged approximately b ext{ around } 0.23 ext{ to } 0.25, with standardized effects eta ext{ around } 0.13 ext{ to } 0.14, and SEs around 0.08 ext{ to } 0.09.

    • Model comparison indicates incremental explanation of variance, with total R^2 values spanning roughly 0.23 to 0.32 across models (Model 4 R^2 ext{ around } 0.32).

  • Implication: The DAT1 effect on delinquent peers in high-risk males persists even after controlling for direct delinquency and other risk factors, suggesting a genuine rGE signal rather than a spurious correlation due to correlated behaviors.

Tables: Core Numerical Findings (Summary)

  • Table 1: Direct Effects of DAT1 on Delinquent Peers (N = 1,816)

    • Full sample: $b = 0.05$, $eta = 0.03$, $SE = 0.04$, $R^2 = 0.09$;

    • Male: $b = 0.17$, $eta = 0.10^{*}$, $SE = 0.06$, $R^2 = 0.10$;

    • Female: $b = -0.06$, $eta = -0.03$, $SE = 0.04$, $R^2 = 0.09$;

    • White: $b = 0.05$, $eta = 0.03$, $SE = 0.04$, $R^2 = 0.09$;

    • Black: $b = 0.12$, $eta = 0.07$, $SE = 0.09$, $R^2 = 0.07$.

  • Table 2: DAT1 Effects by Family Risk (Male Adolescents, White/Black; N = 814 for low-risk/ high-risk groups combined per subgroup)

    • Low-risk: DAT1 effect not statistically significant; age is the main predictor; other covariates non-dominant.

    • High-risk: DAT1 significantly related to delinquent peers; effect persists across models; pattern suggests environment moderates genetic effect.

  • Table 3: Spuriousness Tests (High-Risk Male Adolescents; N ≈ 341)

    • Model 1: $DAT1
      ightarrow ext{delinquent peers}$; $b = 0.23$, $eta = 0.13$, $SE = 0.09$;

    • Model 2: adding Age and Criminal father; $b = 0.25$, $eta = 0.14$, $SE = 0.09$;

    • Model 3: adding Delinquency; $b = 0.22$, $eta = 0.13$, $SE = 0.13$;

    • Model 4: adding Delinquency + Low self-control + Drug/Alcohol; $b = 0.21$, $eta = 0.13$, $SE = 0.08$; $R^2$ values: $0.23$, $0.10$, $0.26$, $0.32$ respectively.

  • Overall pattern: In high-risk males, DAT1’s association with delinquent peers is robust to multiple controls and remains statistically significant in all tested specifications.

Discussion and Interpretation

  • Main finding: An rGE exists between the DAT1 gene and delinquent peer affiliation, but it is not uniform across all groups.

    • Specifically, male adolescents with more DAT1 risk alleles (10R) are more likely to affiliate with delinquent peers, but primarily within high-family-risk environments.

    • In low-risk family contexts, the DAT1 effect on delinquent peer affiliation is not statistically significant.

    • Female adolescents show no significant DAT1 association with delinquent peers in any environ- mental context studied here.

  • The results support an active rGE mechanism: genetic propensities may lead some male youths to seek out delinquent peer groups, especially when the family environment provides fewer protective resources.

  • Theoretical implications:

    • Confirms the idea that genotype and environment are interwoven in complex ways, where genes influence the environments to which individuals are exposed, and environments may activate or mute genetic propensities.

    • Extends prior findings on MAOA and environmental risk to DAT1 and antisocial peer networks.

  • Explanations for gender differences:

    • Parental monitoring may be more effective for sons in low-risk families, potentially attenuating gene-driven selection into delinquent peers for males in low-risk environments.

    • In high-risk families, the 10R DAT1 allele may interact with contextual stressors to promote selection into antisocial peer groups.

  • Limitations and cautions:

    • The DAT1 effect did not generalize to females; results are strongest for male adolescents in high-risk contexts.

    • Delinquent peers measure at Wave 1 captured only drug-using behaviors of friends, not more serious violence or broader antisocial activities.

    • Genotyped subsample (1,816) is substantial but not fully representative; generalizability is limited.

    • Observational design cannot prove causality; however, the robust associations after controlling for multiple covariates strengthen the rGE interpretation.

  • Relation to prior work:

    • Aligns with Iervolino et al. (2002) and Kendler et al. (2007) suggesting genetic contributions to exposure to antisocial peers, while highlighting environmental moderation (family risk) as crucial.

    • Connects to a broader biosocial literature that emphasizes gene–environment interplay in antisocial and externalizing outcomes (Caspi et al. 2002; Moffitt 2005; Walsh 2002).

Implications, Applications, and Future Directions

  • Biosocial approach: the study supports integrating genetic data into criminological and developmental research to better understand how youths select or are exposed to antisocial environments.

  • Policy implications: interventions that bolster family environments (attachment, involvement, and reducing disengagement) may dampen genetic propensities to seek delinquent peers, particularly for at-risk males.

  • Future research directions:

    • Replication in independent samples with more diverse measures of peer delinquency (including violence) and objective behavioral outcomes.

    • Exploration of additional genes and polygenic risk scores to capture a broader genetic architecture of peer selection tendencies.

    • Longitudinal analyses to examine how rGE evolves across adolescence and into early adulthood.

Ethical and Practical Considerations

  • Use of genetic data in criminology requires careful handling to avoid determinism and stigma; emphasis should be on understanding mechanisms to inform prevention and intervention.

  • Findings should not be used to label individuals as “genetically predisposed criminals” but to recognize complex gene–environment interplay and identify protective factors.

  • Data privacy and consent for genetic data in minors are critical; analyses should ensure robust protection of participant information.

Connections to Foundational Principles

  • Differential association and social learning theory underpin the interpretation that peers shape delinquent behavior, while gene–environment interplay provides a mechanism for why some youths opt into or are exposed to these networks.

  • Self-control theory and general strain theory are consistent with the idea that family risk and environmental stressors interact with genetic predispositions to influence antisocial outcomes.

  • The findings reinforce Scarr & McCartney’s (1983) genotype–environment effects framework by demonstrating a measurable rGE in a real-world, nationally representative sample.

Key Formulas and Notation (LaTeX)

  • Allele counts for DAT1:

    • ext{DAT1}_{10R} o ext{number of 10R alleles} \ ext{Possible values: } 0,1,2

    • Distribution in Add Health sample: P(0)=0.053,\, P(1)=0.351,\, P(2)=0.596

  • Delinquent peers measure:

    • DP = x1 + x2 + x3, ext{ where } xi ext{ indicates peer behavior (0/1)}

  • Family risk construct:

    • Let FR^ ext{econ} o egin{cases} 0, & ext{low-risk} \ 1, & ext{high-risk} \ ext{(composite score from maternal attachment, involvement, disengagement)} \ ext{split at mean} \ ext{dichotomized} \ ext{(FR ∈ {0,1})} \ ext{Higher FR indicates higher family risk} \

  • Regression models (example):

    • Base model: DP = eta0 + eta1 ext{DAT1}{10R} + eta2 ext{Age} + eta_3 ext{CriminalFather} + oldsymbol{
      u}

  • Subgroup model for spuriousness check:

    • DP = eta0 + eta1 ext{DAT1}{10R} + eta2 ext{Age} + eta3 ext{CriminalFather} + eta4 ext{Delinquency} + eta5 ext{LowSelfControl} + eta6 ext{DrugAlcoholUse} + ext{error} $$

References (Selected from Article)

  • Iervolino, C. et al. (2002). Genetic and environmental influences in adolescent peer socialization. Child Development.

  • Cleveland, H. H., Wiebe, R. P., & Rowe, D. C. (2005). Sources of exposure to smoking and drinking friends among adolescents: A behavioral-genetic evaluation. The Journal of Genetic Psychology.

  • Kendler, K. S., et al. (2007). Creating a social world: A developmental twin study of peer-group deviance. Archives of General Psychiatry.

  • Caspi, A., & Moffitt, T. E. (1995, 2002). Gene–environment interplay and antisocial behavior literature cited in discussion.

  • Scarr, S., & McCartney, K. (1983). How people make their own environments: A theory of genotype–environment effects. Child Development.

  • Walsh, A. (2002). Essay review. Companions in crime: A biosocial perspective. Human Nature Review.

  • Udry, J. R. (1998, 2003). Add Health design and data files.

  • Warr, M. (1996, 1998, 2002). Works on delinquent peers and social structure in crime.

  • Moffitt, T. E. (2005). The new look of behavioral genetics in developmental psychopathology.

  • Caspi, A., et al. (2002). Role of genotype in the cycle of violence in maltreated children. Science.

Summary Takeaways

  • DAT1 10R allele is linked to higher delinquent peer affiliation, but primarily for male adolescents in high-risk family environments.

  • The effect persists after accounting for delinquency, self-control, and drug/alcohol use, supporting a genuine gene–environment correlation rather than a spurious association.

  • The results highlight the importance of examining interactions between genes and environment, and they demonstrate that genetic influences on social experiences can be conditional on context (family risk) and gender.

  • The study advances a biosocial framework in criminology and suggests avenues for prevention that bolster family environments to potentially mitigate genetic propensities toward delinquent peer networks.