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Homeostasis

Introduction

  • Size and shape affect the way an animal interacts with its environment

  • Rate of exchange is proportional to a cell’s surface area while amount of exchange material is proportional to a cell’s volume

  • More complex organisms have highly folded internal surfaces for exchanging materials

  • In vertebrates, the space between cells is filled with interstitial fluid, which allows for the movement of material into and out of cells

Organization of Animal Bodies

  • All animal cells share similarities in the ways in which they

    • Exchange materials with their surroundings

    • Obtain energy from organic nutrients

    • Synthesize complex molecules

    • Reproduce themselves

    • Detect and respond to signals in their immediate environment

Tissues are classified into four main categories: epithelial, connective, muscle, and nervous

Epithelial Tissue

  • Epithelial tissue: covers the outside of the body and lines the organs and cavities within the body

    • It contains cells that are closely joined

  • The shape of epithelial cells may be

    • cuboidal (like dice)

    • columnar (like bricks on end)

    • squamous (like floor tiles)

  • The arrangement of epithelial cells may be

    • simple (single cell layer)

    • stratified (multiple tiers of cells)

    • pseudostratified (a single layer of cells of varying length)

Connective Tissue

  • Connect, anchor, and support

  • Includes blood, adipose, bone, cartilage, loose and dense connective tissue

  • Form extracellular matrix around cells

    • provides scaffold for attachment

    • Protects and cushions

    • mechanical strength

    • Transmit information

Nervous Tissue

  • Nervous tissue: initiate and conduct electrical signals from one part of the animal’s body to another

  • Neuron: single nerve cell

  • Electrical signals produced in a nerve cell may stimulate or inhibit other cells to

    • Initiate new action potentials in other neurons

    • Stimulate muscle to contract

    • Stimulate glands to release chemicals

Vertebrates

  • In vertebrates, the fibers and foundation combine to form six major types of connective tissue:

    • Loose connective tissue: binds epithelia to underlying tissues and holds organs in place

    • Cartilage: a strong and flexible support material

    • Fibrous connective tissue: is found in tendons and ligaments

      • Tendons: attach muscles to bones

      • Ligaments: connect bones at joints

    • Adipose tissue: stores fat for insulation and fuel

    • Blood: composed of blood cells and cell fragments in blood plasma

    • Bone: mineralized and forms the skeleton

Coordination and Control

  • Control and coordination within a body depend on the endocrine system and the nervous system

    • Endocrine system: transmits chemical signals called hormones to receptive cells throughout the body via blood

      • A hormone may affect one or more regions throughout the body

      • Hormones are relatively slow acting, but can have long-lasting effects

    • Nervous system: transmits information between specific locations

      • The information conveyed depends on a signal’s pathway, not the type of signal

      • Nerve signal transmission is very fast

      • Nerve impulses can be received by neurons, muscle cells, endocrine cells, and exocrine cells

Feedback Control

  • Feedback control: maintains the internal environment in many animals

  • Animals manage their internal environment by regulating or conforming to the external environment

    • Regulator: uses internal control mechanisms to moderate internal change in the face of external, environmental fluctuation

    • Conformer: allows its internal condition to vary with certain external changes

    • Animals may regulate some environmental variables while conforming to others

Homeostatic Control Systems

  • Set point: normal value for controlled variable

  • Sensor: monitors particular variable

  • Integrator: compares signals from the sensor to set point

  • Effector: compensates for deviations between actual value and set point

  • Example: body temperature in mammals

  • Organisms use homeostasis to maintain a

    “steady state” or internal balance regardless

    of external environment

  • Acclimatization: homeostasis can adjust to changes in external environment

  • Thermoregulation: adaptation to the thermal environment

  • Osmoregulation: adaptation to the osmotic environment

  • Excretion: strategies for the elimination of waste products of protein catabolism

Thermoregulation

  • Homeostatic processes for thermoregulation involve form, function, and behavior

  • Thermoregulation: the process by which animals maintain an internal temperature within a tolerable range

    • Endothermic animals: generate heat by metabolism; birds and mammals are endotherms

    • Ectothermic animals: gain heat from external sources ectotherms include most invertebrates, fishes, amphibians, and nonavian reptiles

      • In general, ectotherms tolerate greater variation in internal temperature, while endotherms are active at a greater range of external temperatures

      • Endothermy is more energetically expensive than ectothermy

  • Heat regulation in mammals often involves the integumentary system: skin, hair, and nails

  • Five adaptations help animals thermoregulate:

    • insulation = skin, fur, feathers, blubber

    • circulatory adaptations= vasodilation and vasoconstriction

    • cooling by evaporative heat loss

    • behavioral responses

    • adjusting metabolic heat production

Behavioral Responses

  • In winter, many animals bask in the sun or on warm rocks.

  • In summer, many animals burrow or move to damp areas.

  • Some animals migrate to more suitable climates.

Physiological Thermostats and Fever

  • Thermoregulation is controlled by a region of the brain called the hypothalamus

  • The hypothalamus triggers heat loss or heat generating mechanisms

  • Fever is the result of a change to the set point for a biological thermostat

Negative Feedback

  • Negative feedback: the variable being regulated brings about responses that move the variable in the opposite direction

  • ex: Decrease in body temperature leads to responses that increase body temperature

  • May occur at cellular or molecular level

  • Also prevents homeostatic responses from overcompensating

Positive Feedback

  • Positive feedback: reinforces the direction of change

  • Far less common

  • Accelerates a process

    • Explosive system

  • ex: Birth in mammals

Feedforward Regulation

  • Feedforward regulation: animal’s body begins preparing for a change in some variable before it occurs

  • Anticipatory

  • Speeds up homeostatic responses and minimizes deviations from the set point

  • Many result from or are modified by learning

Homeostasis

Introduction

  • Size and shape affect the way an animal interacts with its environment

  • Rate of exchange is proportional to a cell’s surface area while amount of exchange material is proportional to a cell’s volume

  • More complex organisms have highly folded internal surfaces for exchanging materials

  • In vertebrates, the space between cells is filled with interstitial fluid, which allows for the movement of material into and out of cells

Organization of Animal Bodies

  • All animal cells share similarities in the ways in which they

    • Exchange materials with their surroundings

    • Obtain energy from organic nutrients

    • Synthesize complex molecules

    • Reproduce themselves

    • Detect and respond to signals in their immediate environment

Tissues are classified into four main categories: epithelial, connective, muscle, and nervous

Epithelial Tissue

  • Epithelial tissue: covers the outside of the body and lines the organs and cavities within the body

    • It contains cells that are closely joined

  • The shape of epithelial cells may be

    • cuboidal (like dice)

    • columnar (like bricks on end)

    • squamous (like floor tiles)

  • The arrangement of epithelial cells may be

    • simple (single cell layer)

    • stratified (multiple tiers of cells)

    • pseudostratified (a single layer of cells of varying length)

Connective Tissue

  • Connect, anchor, and support

  • Includes blood, adipose, bone, cartilage, loose and dense connective tissue

  • Form extracellular matrix around cells

    • provides scaffold for attachment

    • Protects and cushions

    • mechanical strength

    • Transmit information

Nervous Tissue

  • Nervous tissue: initiate and conduct electrical signals from one part of the animal’s body to another

  • Neuron: single nerve cell

  • Electrical signals produced in a nerve cell may stimulate or inhibit other cells to

    • Initiate new action potentials in other neurons

    • Stimulate muscle to contract

    • Stimulate glands to release chemicals

Vertebrates

  • In vertebrates, the fibers and foundation combine to form six major types of connective tissue:

    • Loose connective tissue: binds epithelia to underlying tissues and holds organs in place

    • Cartilage: a strong and flexible support material

    • Fibrous connective tissue: is found in tendons and ligaments

      • Tendons: attach muscles to bones

      • Ligaments: connect bones at joints

    • Adipose tissue: stores fat for insulation and fuel

    • Blood: composed of blood cells and cell fragments in blood plasma

    • Bone: mineralized and forms the skeleton

Coordination and Control

  • Control and coordination within a body depend on the endocrine system and the nervous system

    • Endocrine system: transmits chemical signals called hormones to receptive cells throughout the body via blood

      • A hormone may affect one or more regions throughout the body

      • Hormones are relatively slow acting, but can have long-lasting effects

    • Nervous system: transmits information between specific locations

      • The information conveyed depends on a signal’s pathway, not the type of signal

      • Nerve signal transmission is very fast

      • Nerve impulses can be received by neurons, muscle cells, endocrine cells, and exocrine cells

Feedback Control

  • Feedback control: maintains the internal environment in many animals

  • Animals manage their internal environment by regulating or conforming to the external environment

    • Regulator: uses internal control mechanisms to moderate internal change in the face of external, environmental fluctuation

    • Conformer: allows its internal condition to vary with certain external changes

    • Animals may regulate some environmental variables while conforming to others

Homeostatic Control Systems

  • Set point: normal value for controlled variable

  • Sensor: monitors particular variable

  • Integrator: compares signals from the sensor to set point

  • Effector: compensates for deviations between actual value and set point

  • Example: body temperature in mammals

  • Organisms use homeostasis to maintain a

    “steady state” or internal balance regardless

    of external environment

  • Acclimatization: homeostasis can adjust to changes in external environment

  • Thermoregulation: adaptation to the thermal environment

  • Osmoregulation: adaptation to the osmotic environment

  • Excretion: strategies for the elimination of waste products of protein catabolism

Thermoregulation

  • Homeostatic processes for thermoregulation involve form, function, and behavior

  • Thermoregulation: the process by which animals maintain an internal temperature within a tolerable range

    • Endothermic animals: generate heat by metabolism; birds and mammals are endotherms

    • Ectothermic animals: gain heat from external sources ectotherms include most invertebrates, fishes, amphibians, and nonavian reptiles

      • In general, ectotherms tolerate greater variation in internal temperature, while endotherms are active at a greater range of external temperatures

      • Endothermy is more energetically expensive than ectothermy

  • Heat regulation in mammals often involves the integumentary system: skin, hair, and nails

  • Five adaptations help animals thermoregulate:

    • insulation = skin, fur, feathers, blubber

    • circulatory adaptations= vasodilation and vasoconstriction

    • cooling by evaporative heat loss

    • behavioral responses

    • adjusting metabolic heat production

Behavioral Responses

  • In winter, many animals bask in the sun or on warm rocks.

  • In summer, many animals burrow or move to damp areas.

  • Some animals migrate to more suitable climates.

Physiological Thermostats and Fever

  • Thermoregulation is controlled by a region of the brain called the hypothalamus

  • The hypothalamus triggers heat loss or heat generating mechanisms

  • Fever is the result of a change to the set point for a biological thermostat

Negative Feedback

  • Negative feedback: the variable being regulated brings about responses that move the variable in the opposite direction

  • ex: Decrease in body temperature leads to responses that increase body temperature

  • May occur at cellular or molecular level

  • Also prevents homeostatic responses from overcompensating

Positive Feedback

  • Positive feedback: reinforces the direction of change

  • Far less common

  • Accelerates a process

    • Explosive system

  • ex: Birth in mammals

Feedforward Regulation

  • Feedforward regulation: animal’s body begins preparing for a change in some variable before it occurs

  • Anticipatory

  • Speeds up homeostatic responses and minimizes deviations from the set point

  • Many result from or are modified by learning

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