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Chapter 1: Evolution, the Themes of Biology, and Scientific Inquiry

Introduction to Biology

  • Biology is the scientific study of life.

  • Recognizes life through the activities of living organisms.

  • Biology is a subject of enormous scope.

  • Taxonomy: study of biological names

Unifying Themes in Biology

  • Five unifying themes:

    • Organization: Life is structured hierarchically.

    • Information: Genetic information guides development and functioning.

    • Energy and Matter: Life relies on energy transformation.

    • Interactions: Interactions shape ecosystems and biological processes.

    • Evolution: Explains the unity and diversity of life.

Properties of Life

  • Key characteristics include:

    • Order: Organized structures of living organisms.

    • Regulation: Homeostasis and regulation of internal environments.

    • Reproduction: Ability to reproduce and pass on genetic information.

    • Adaptation: Adjustments to environmental changes over generations.

    • Response to Environment: Organisms react to stimuli from their surroundings.

    • Energy Processing: Utilization of energy for growth and survival.

Biological Organization

  • Life can be studied at various levels:

    • Molecules, Cells, Tissues, Organs, Organisms, Populations, Communities, Ecosystems, Biosphere.

  • Reductionism: Breaking complex systems into simpler parts for study.

Emergent Properties

  • Result from the arrangement and interactions of components.

  • Nonbiological examples, like bicycles, illustrate emergent properties.

  • Systems biology examines interactions among biological system parts.

  • Can be used to study life at all levels.

Structure and Function

  • At each level of the biological hierarchy we find a correlation between structure and function.

The Cell

  • Basic unit of structure and function in life.

  • Smallest unit of organization that perform all activities required for life.

  • Cell Theory: All living organisms are composed of cells.

  • Two types:

    • Prokaryotic: Simple, no nucleus (e.g., bacteria and archaea).

    • Eukaryotic: Complex, membrane-enclosed organelles, with nucleus (e.g., plants, animals).

Genetic Information

  • Chromosomes contain DNA, the genetic material.

  • DNA (deoxyribonucleic acid)

  • DNA holds genes that encode for proteins and direct development.

  • Genes: the units of inheritance.

  • Made up of two long chains arranged in a double helix; each chain made up of four kinds of chemical building blocks called nucleotides and abbreviated A, C, G, T.

  • A: adenine

  • C: cytosine

  • G: guanine

  • T: thymine

  • (A+T) (G+C)

  • Gene expression: the process of converting information from gene to cellular product.

Genomics and Proteomics

  • Genomics: Study of entire genetic sequences.

  • Genome: entire “library” of genetic instructions.

  • Proteomics: Analysis of whole sets of proteins in organisms.

  • Proteome: the entire set of proteins expressed by a given cell, tissue, or organ.

  • Bioinformatics: the use of computational tools to process a large volume of data very rapidly.

Energy and Matter Transfer

  • Energy input from the sun drives life processes.

  • Photosynthetic organisms convert solar energy into chemical energy.

  • Energy flows through ecosystems; chemicals cycle among organisms.

Interactions in Biological Systems

  • Essential for organism function and ecosystem stability.

  • Feedback mechanisms (negative and positive) regulate biological processes.

  • Feedback regulation: the output, or product of a process, regulates that very process.

Ecosystem Interactions

  • Organisms interact with each other and their physical environment.

  • Human impacts contribute to climate change and habitat loss.

Core Theme: Evolution

  • Key unifying concept explaining diversity of life.

  • Understanding of evolution aids in comprehending biological relationships.

  • Natural Selection: Mechanism through which evolution occurs.

Classification of Life

  • Approximately 1.8 million species identified.

  • Each species is given a two-part name: The genus, to which the species belongs, and a species name unique to that species. (e.g., Homo sapiens)

  • Organisms classified into three domains:

    • Bacteria, Archaea, Eukarya.

  • Eukarya includes the four subgroups:

    • Plants; which produce their own food by photosynthesis.

    • Fungi; which absorb nutrients.

    • Animals; which ingest their food.

    • Protists; which can either consume or produce their foods.

Darwin and Evolution

  • On the Origin of Species by Means of Natural Selection (1859).

  • Introduced natural selection as a driving force behind adaptation.

  • He made two points:

    • Species showed evidence of “descent with modification” from common ancestors.

    • “Natural Selection” is the mechanism behind descent with modification.

  • Observed variations in traits and implications for species survival.

Scientific Inquiry

  • Science is a process of inquiry involving observation and hypothesis testing.

  • The word science is derived from Latin and means “to know”.

  • Methods include gathering data, forming and testing hypotheses, and utilizing inductive and deductive reasoning.

  • Controlled experiment: an experimental group is compared with a control group.

  • Independent variable: the one that is manipulated by the researchers.

  • Dependent variable: the one predicted to be affected in response.