Basal Metabolic Rate (BMR) β ~60β75% of TEE (Total Energy Expenditure)
Primary determinant: lean body mass (muscle)
Decline with age: ~1β2% per decade after age 30
Other factors affecting BMR: age, gender, genetics, hormones, body size, temperature, stress
Thermic Effect of Food (TEF) β ~5β10% of TEE
Energy used to digest, absorb, and store food
Physical Activity β ~15β35% of TEE (most variable)
Non-exercise Activity Thermogenesis (NEAT): minor but included in PA
Hunger: physiological drive to eat
Appetite: psychological desire for specific foods
Formula: weight (kg) / heightΒ² (mΒ²)
Classifications:
Underweight: <18.5
Normal: 18.5β24.9
Overweight: 25β29.9
Obese: β₯30
Limitations: Does not account for muscle mass, bone density, fat distribution
Body Composition: % fat vs. lean mass
Upper-body (android) obesity: more common in males; higher health risks
Lower-body (gynoid) obesity: more common in females; less risk
Safe loss: 1β2 lbs/week
Caloric deficit per pound of fat: 3,500 kcal
% of U.S. adults obese: ~42%
Risk factors: genetics, environment, behavior, metabolism
Anorexia Nervosa: severe caloric restriction, fear of weight gain, low body weight
Bulimia Nervosa: binge eating followed by purging (vomiting/laxatives); purging is not fully effective at preventing calorie absorption
RED-S (Relative Energy Deficiency in Sport): low energy availability affecting health/performance
Female Athlete Triad: low energy β menstrual dysfunction β low bone density
Deficiency: most common nutrient deficiency worldwide
Forms:
Heme iron: from animal sources; better absorbed
Non-heme iron: from plant sources
Enhancers: vitamin C, MFP factor (meat, fish, poultry)
Inhibitors: phytates, calcium, polyphenols, tannins
At-risk groups: women, infants, teens, vegetarians
Role: needed for thyroid hormone synthesis
Deficiency: goiter, cretinism (in infants)
Deficiency: can lead to heart disease (Keshan disease)
Function: strengthens enamel, prevents dental caries
Toxicity: fluorosis (mottled teeth)
Steps:
Initiation β DNA mutation
Promotion β altered cells divide
Progression β cells become malignant
Metastasize: spread to other tissues
Prevention guidelines: fruits, vegetables, fiber, limit red/processed meat, donβt smoke, healthy weight
Prevents neural tube defects
Need increases in early pregnancy
Normal BMI: gain 25β35 lbs
Varies based on prepregnancy weight
Avoid: raw fish/meat, unpasteurized cheese, deli meats (Listeria), high-mercury fish
For mother: bonding, reduced disease risk
Colostrum: first milk, rich in antibodies
Prevention: vitamin K injection at birth
Exclusive for 6 months; continue with food for 12+ months
Limit juice to 4β6 oz/day
Introduce reduced-fat milk at age 2
Start at ~6 months
Avoid choking hazards: grapes, hot dogs, nuts
Avoid honey (botulism risk)
BMI-for-age percentiles:
Overweight: 85thβ94th percentile
Obese: β₯95th percentile
Usual aging: normal decline
Successful aging: minimal disease, high function
Calories: decrease with age
Protein: needs may increase to prevent sarcopenia
Fat: moderate intake, focus on quality
Especially those 65+ living alone, low income, or with illness
Disease
Dysfunction
Dementia
Drugs
Dysphagia
Dysgeusia (taste loss)
Dentition (poor teeth)
Diarrhea
Depression