Renal System and Urinary Anatomy
Objectives of the Renal System Study
- Students will distinguish structures and functions of the urinary system
- Understand differences between male and female urinary tracts
- Describe the blood flow through the kidneys
- Understand nephron structures and their functions
- Learn fluid transportation through the urinary system
- Understand urine formation, composition, and qualities
- Recognize clinical implications of abnormal urinalysis and urinary tract infections (UTIs)
Key Terms and Definitions
Terminology
- Urine: Liquid waste produced by the kidneys.
- Urea: A component of urine, formed by the breakdown of proteins in food.
- Renal hilus: External anatomy with medial indentation of the kidney.
- Renal capsule: Fibrous external covering of the kidney.
- Adrenal gland: Endocrine gland on the kidney's superior surface.
- Cortex: Most superficial region of internal kidney anatomy.
- Medulla: Inner kidney region, deeper than the cortex.
- Renal pyramids: Triangular regions of the medulla, striped appearance due to urine-collecting tubules.
- Renal calyx: Cup-shaped area collecting urine from the renal pyramids.
- Renal artery: Vessel carrying blood into the kidneys from the descending aorta.
Nephron Functions
- Renal vein: Carries blood from the kidneys to the inferior vena cava.
- Nephron: Filtering unit of the kidneys; each kidney contains over 1 million nephrons.
- Glomerulus: A ball of capillaries in the nephron where blood filtration occurs.
- Renal tubule: Twisted, coiled tube of the nephron that connects to collecting ducts.
- Bowman's capsule: Cup-shaped end of the renal tubule surrounding the glomerulus.
- Filtration: Nonselective process where blood pressure pushes fluids and solutes out into the glomerular capsule.
- Filtrate: The fluid in the renal tubule post-filtration.
- Reabsorption: The process where useful substances like water, glucose, and ions are moved back into the blood.
- Secretion: Active transport of substances from blood into the tubule for urine formation.
- Afferent arteriole: Brings blood into the glomerulus.
- Efferent arteriole: Drains blood from the glomerulus into peritubular capillaries.
Urinary System Overview
- Kidneys: Filter blood, remove waste, convert filtrate into urine.
- Ureters: Transport urine from kidneys to urinary bladder.
- Bladder: Expandable muscular sac storing up to 1 L of urine.
- Urethra: Eliminates urine from the body; longer in males than in females.
- Functions: Elimination of metabolic wastes, regulation of ion levels and acid-base balance, regulation of blood pressure, and formation of erythropoietin.
Urinary System Anatomy
Kidney Structure
- Hilum: Vessels and nerves connect to the kidney.
- Renal artery: Transports blood to the kidney; renal vein filters and exits blood from the kidney.
- Renal cortex: Outer functional tissue; renal medulla: inner functional tissue.
Nephron Composition
- Components: Consists of renal corpuscle (glomerulus and Bowman's capsule) and renal tubule (PCT, nephron loop, DCT).
- Juxtaglomerular Apparatus: Regulates blood filtrate formation and blood pressure; contains granular cells that produce renin.
Urinary Tract Infections (UTIs)
- Urethritis: Infection begins in urethra.
- Cystitis: Infection spreads to the bladder.
- Pyelonephritis: Infection spreads to the kidneys.
- Symptoms: Painful urination, frequent urination, pressure, back pain, nausea.
Renin-Angiotensin-Aldosterone System
- Mechanisms: Activated by juxtaglomerular complex, leading to renin production.
- Renin activates angiotensin I, converted to angiotensin II, which constricts arterioles and increases aldosterone secretion, raising blood pressure and improving glomerular filtration rate (GFR).
Urine Transport and Storage
- Ureters: Conduct urine from kidneys to the bladder; their mucosa is distensible to store urine.
- Urinary bladder: Expandable container for urine.
- Urethra: Conducts urine out of the body; has internal (involuntary) and external (voluntary) sphincters.
- Male Urethra: Passageway for urine and semen, consists of three segments: prostatic, membranous, and spongy urethra.
Conclusion
- Understanding the urinary system's anatomy, functions, and clinical aspects is crucial for identifying and treating conditions related to renal health.