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Renal System and Urinary Anatomy

Objectives of the Renal System Study

  • Students will distinguish structures and functions of the urinary system
  • Understand differences between male and female urinary tracts
  • Describe the blood flow through the kidneys
  • Understand nephron structures and their functions
  • Learn fluid transportation through the urinary system
  • Understand urine formation, composition, and qualities
  • Recognize clinical implications of abnormal urinalysis and urinary tract infections (UTIs)

Key Terms and Definitions

Terminology

  • Urine: Liquid waste produced by the kidneys.
  • Urea: A component of urine, formed by the breakdown of proteins in food.
  • Renal hilus: External anatomy with medial indentation of the kidney.
  • Renal capsule: Fibrous external covering of the kidney.
  • Adrenal gland: Endocrine gland on the kidney's superior surface.
  • Cortex: Most superficial region of internal kidney anatomy.
  • Medulla: Inner kidney region, deeper than the cortex.
  • Renal pyramids: Triangular regions of the medulla, striped appearance due to urine-collecting tubules.
  • Renal calyx: Cup-shaped area collecting urine from the renal pyramids.
  • Renal artery: Vessel carrying blood into the kidneys from the descending aorta.

Nephron Functions

  • Renal vein: Carries blood from the kidneys to the inferior vena cava.
  • Nephron: Filtering unit of the kidneys; each kidney contains over 1 million nephrons.
  • Glomerulus: A ball of capillaries in the nephron where blood filtration occurs.
  • Renal tubule: Twisted, coiled tube of the nephron that connects to collecting ducts.
  • Bowman's capsule: Cup-shaped end of the renal tubule surrounding the glomerulus.
  • Filtration: Nonselective process where blood pressure pushes fluids and solutes out into the glomerular capsule.
  • Filtrate: The fluid in the renal tubule post-filtration.
  • Reabsorption: The process where useful substances like water, glucose, and ions are moved back into the blood.
  • Secretion: Active transport of substances from blood into the tubule for urine formation.
  • Afferent arteriole: Brings blood into the glomerulus.
  • Efferent arteriole: Drains blood from the glomerulus into peritubular capillaries.

Urinary System Overview

  • Kidneys: Filter blood, remove waste, convert filtrate into urine.
  • Ureters: Transport urine from kidneys to urinary bladder.
  • Bladder: Expandable muscular sac storing up to 1 L of urine.
  • Urethra: Eliminates urine from the body; longer in males than in females.
  • Functions: Elimination of metabolic wastes, regulation of ion levels and acid-base balance, regulation of blood pressure, and formation of erythropoietin.

Urinary System Anatomy

Kidney Structure

  • Hilum: Vessels and nerves connect to the kidney.
  • Renal artery: Transports blood to the kidney; renal vein filters and exits blood from the kidney.
  • Renal cortex: Outer functional tissue; renal medulla: inner functional tissue.

Nephron Composition

  • Components: Consists of renal corpuscle (glomerulus and Bowman's capsule) and renal tubule (PCT, nephron loop, DCT).
  • Juxtaglomerular Apparatus: Regulates blood filtrate formation and blood pressure; contains granular cells that produce renin.

Urinary Tract Infections (UTIs)

  • Urethritis: Infection begins in urethra.
  • Cystitis: Infection spreads to the bladder.
  • Pyelonephritis: Infection spreads to the kidneys.
  • Symptoms: Painful urination, frequent urination, pressure, back pain, nausea.

Renin-Angiotensin-Aldosterone System

  • Mechanisms: Activated by juxtaglomerular complex, leading to renin production.
  • Renin activates angiotensin I, converted to angiotensin II, which constricts arterioles and increases aldosterone secretion, raising blood pressure and improving glomerular filtration rate (GFR).

Urine Transport and Storage

  • Ureters: Conduct urine from kidneys to the bladder; their mucosa is distensible to store urine.
  • Urinary bladder: Expandable container for urine.
  • Urethra: Conducts urine out of the body; has internal (involuntary) and external (voluntary) sphincters.
  • Male Urethra: Passageway for urine and semen, consists of three segments: prostatic, membranous, and spongy urethra.

Conclusion

  • Understanding the urinary system's anatomy, functions, and clinical aspects is crucial for identifying and treating conditions related to renal health.