SOLVENTEN & REAGENTIA

SOLVENTEN

• Non-Polar Solvents

  • Hexane

  • Toluene

• Moderately Polar (Aprotic) Solvent = droge ethers

• altijd gebruiken bij Grignard reagens, want sterk basisch nucleofiel!!

  • (Diethyl) ether

  • Tetrahydrofuran (THF)

• Polar Aprotic Solvents

  • Dimethyl sulfoxide (DMSO)

  • N,N-Dimethylformamide (DMF)

• Polar Protic Solvents

  • Water

  • Methanol

  • Ethanol

  • Isopropanol

REAGENTIA

• Acids

  • Sulfuric acid (H₂SO₄)

  • Hydrochloric acid (HCl)

  • Nitric acid (HNO₃)

  • Acetic acid (CH₃COOH)

  • p-Toluenesulfonic acid (TsOH)

• Bases

  • Sodium hydroxide (NaOH)

  • Potassium hydroxide (KOH)

  • Pyridine

  • Sodium hydride (NaH)

• Oxidizing Agents

  • Potassium permanganate (KMnO₄)

  • Chromic acid (H₂CrO₄)

  • PCC (Pyridinium chlorochromate)

  • Jones reagent (CrO₃/H₂SO₄)

  • Oxalylchloride (COCl)₂

  • m-CPBA (meta-chloroperbenzoic acid)

• Reducing Agents

  • Lithium aluminum hydride (LiAlH₄)

  • Sodium borohydride (NaBH₄)

  • Hydrogen gas (H₂) with Pd/C

  • DIBAL-H = DIBAH (Diisobutylaluminum hydride)

  • BH₃·THF

• Halogenation and Substitution Reagents

  • Thionyl chloride (SOCl₂)

  • N-Bromosuccinimide (NBS)

• Grignard and Organometallic Reagents

  • Grignard reagents (RMgX)

  • Organolithium reagents (RLi)

  • Gilman reagents (R₂CuLi)

EXTRA