Urinary Anatomy & Histology

Urinary Anatomy & Histology Detailed Study Notes

Models of the Urinary System

  • Outline of significant structures modeled:

    1. Kidney

      • Right and Left kidneys distinguished.

    2. Fibrous Capsule

      • Protective outer layer of the kidney.

    3. Renal Pyramid

      • Cone-shaped tissues of the renal medulla.

    4. Renal Pelvis

      • Central cavity that collects urine.

    5. Minor Calyx

      • Collects urine from renal papillae; smaller cavities.

    6. Major Calyx

      • Formed by the convergence of minor calyces; leads to renal pelvis.

    7. Renal Papillae

      • Tips of the renal pyramids where urine drains.

    8. Renal Column

      • Tissue between renal pyramids; composed of cortical tissue.

    9. Renal Cortex

      • Outer region of the kidney containing renal corpuscles and tubules.

    10. Renal Medulla

      • Inner region containing renal pyramids.

    11. Renal Hilum

      • Entry and exit point for blood vessels, nerves, and ureter.

    12. Renal Corpuscle

      • Structural and functional unit of the kidney.

    13. Glomerulus

      • Network of capillaries within the renal corpuscle; site of filtration.

    14. Efferent Arteriole

      • Carries blood away from the glomerulus.

    15. Afferent Arteriole

      • Brings blood to the glomerulus.

    16. Glomerular Capsule

      • Encloses the glomerulus; also known as Bowman’s capsule.

    17. Bowman’s Space

      • Space between the glomerulus and the glomerular capsule where filtrate collects.

    18. Podocytes

      • Specialized cells in the glomerulus that form filtration slits.

    19. Juxtaglomerular Apparatus

      • Structure regulating blood pressure and glomerular filtration rate.

    20. Macula Densa

      • Specialized cells in the distal convoluted tubule sensing sodium concentration.

    21. Renal Tubule

      • Continues from glomerular capsule; includes various segments.

    22. Proximal Convoluted Tubule

      • First segment of renal tubule involved in reabsorption.

    23. Loop of Henle

      • Consists of descending and ascending limbs with thick and thin segments; plays crucial role in concentration of urine.

    24. Distal Convoluted Tubule

      • Final segment of the renal tubule; involved in secretion and further reabsorption.

    25. Collecting Duct

      • Receives urine from nephrons and helps in concentration.

    26. Juxtamedullary Nephron

      • Nephron type with long loops of Henle; essential for urine concentration.

    27. Cortical Nephron

      • Nephron type mostly located in the renal cortex.

    28. Renal Artery and Vein

      • Supplies blood to the kidney and returns it to the body, respectively.

    29. Segmental Artery

      • Branches of the renal artery; supply blood to the kidney.

    30. Interlobar Artery and Vein

      • Transition between segmental and arcuate vessels; travel between renal columns.

    31. Arcuate Artery and Vein

      • Arch over the bases of the pyramids.

    32. Cortical Radiate Artery and Vein

      • Supply blood to the renal cortex; branches of the arcuate vessels.

    33. Peritubular Capillaries

      • Surround nephron tubules; involved in reabsorption and secretion.

    34. Vasa Recta

      • Capillary loops in the medulla; associated with juxtamedullary nephrons.

    35. Ureters

      • Tubes carrying urine from kidneys to bladder.

Additional Structures

  • Further anatomical features:

    1. Internal Urethral Sphincter

      • Muscular structure; controls urine release in both males and females.

    2. Prostate Gland

      • Gland in males; produces seminal fluid and plays a role in urinary control.

    3. Male Urethra

      • Divided into prostatic and spongy urethra sections.

    4. Female Urethra

      • Single tube transporting urine from the bladder.

    5. Bladder

      • Muscular sac for urine storage.

    6. Detrusor Muscle

      • Smooth muscle layer of the bladder; contracts during urination.

    7. Rugae

      • Folds in the bladder lining; allow for expansion.

  • Additional Images:

    • Structures to visualize:

    • External Urethral Sphincter (male and female).

    • Membranous Urethra.

Kidney Dissection

  • Key dissection points for anatomical understanding:

    1. Renal Capsule

    2. Renal Pyramid

    3. Renal Pelvis

    4. Minor Calyx

    5. Major Calyx

    6. Renal Papillae

    7. Renal Column

    8. Renal Cortex

    9. Renal Medulla

    10. Renal Hilum

    11. Ureter

Functions of Urinary Structures

  • Detailed roles of key components:

    1. Kidney

      • Filters blood, regulates fluid and electrolyte balance.

    2. Nephron

      • Functional unit of the kidney; essential for filtration, reabsorption, and urine formation.

    3. Glomerulus

      • Site of primary filtration of blood.

    4. Glomerular Capsule

      • Collects filtrate from the glomerulus.

    5. Proximal Convoluted Tubule

      • Reabsorbs nutrients, ions, and water from filtrate.

    6. Podocytes

      • Regulate filtration through slits in the glomerular capsule.

    7. Juxtaglomerular Apparatus

      • Detects blood pressure changes; regulates renal blood flow.

    8. Loop of Henle

      • Concentrates urine; establishes medullary concentration gradient.

    9. Distal Convoluted Tubule

      • Further modifies filtrate; important for acid-base balance.

    10. Collecting Duct

      • Final concentration of urine occurs here before it exits the body.

    11. Afferent Arteriole

      • Supplies blood to the glomerulus.

    12. Efferent Arteriole

      • Drains blood from the glomerulus after filtration.

    13. Peritubular Capillaries

      • Aid in reabsorption during urine formation.

    14. Vasa Recta

      • Supply nutrients to the renal medulla and assist in counter-current exchange.

    15. Renal Artery and Vein

      • Ensure supply and drainage of blood in and out of the kidney.

    16. Ureter

      • Conducts urine to the bladder.

    17. Bladder

      • Stores urine until expulsion.

    18. Urethra

      • Conducts urine from bladder to the external environment.

Urine and Fluid Flow Summary

  • Pathway and mechanisms involved:

  • Blood flow through vessels: Glomerular filtration initiates urine formation.

  • Urine flow: From nephrons through collecting ducts into the renal pelvis, then to ureters.

  • Fluid flow through nephron: Involves filtration, reabsorption, and secretion processes.

Histology of the Kidney

  • Microscopic examination points:

    1. 4X Objective for Kidney: Identify the broad structures of cortex and medulla.

    2. 40X Objective for Kidney: Detailed examination of renal corpuscles, glomerulus, capsule, and Bowman’s space.

Histology of the Bladder

  • Microscopic examination points:

    1. 4X Objective for Bladder: General appearance of epithelium and detrusor muscle.

    2. 40X Objective for Bladder: Transitional epithelium, adaptive to stretching during bladder filling.