Physiological Role: Autonomous control of internal organs; involuntary control
Division: Sympathetic (fight or flight) and parasympathetic (rest and digest)
Sympathetic: Originates in thoracolumbar region; short preganglionic neuron, long postganglionic neuron.
Parasympathetic: Originates in brainstem/sacral region; long preganglionic neuron, short postganglionic neuron.
Efferent Neurons: Transmit signals from CNS to effectors like muscles and glands.
Somatic Neurons: Control voluntary movement; directly initiate muscle contractions.
Autonomic Neurons: Control involuntary functions; regulates heart rate, digestion, etc.
Sympathetic: Mostly norepinephrine (adrenergic receptors).
Parasympathetic: Acetylcholine (cholinergic receptors).
Two Neuron System: Preganglionic neuron -> Ganglion (first neuron) -> Postganglionic neuron.
Divergence: Preganglionic neurons can connect to multiple postganglionic neurons.
Neurotransmitter Synthesis: ACh and NE synthesized in the axon terminals. Reception via specific receptor types (nAChR, adrenergic).
Function: Releases catecholamines (epinephrine, norepinephrine) to enhance sympathetic responses during stress.
Role in Homeostasis: Regulates body systems, balances sympathetic and parasympathetic activity for optimal function (e.g., heart rate, digestive activity).
Tonic Control: Continuous regulation (e.g., blood vessels).
Antagonistic Control: Sympathetic and parasympathetic branches often have opposing effects on the same organ.
Varied Responses: Different receptors can cause different responses in different tissues (e.g., adrenergic receptors in blood vessels: vasoconstriction vs vasodilation).