Lecture: 1.1
Objectives / Summary:
Anatomy: Study of structure, structure without function is empty
Heart, leg, eyes, etc
Physiology: Study of function, function without structure is without mechanism
How the functions shape the structure.
What is a structure-function relationship?
The link between the structure of an anatomical feature and its function.
Scenario… Dehydration Sweat Example
Skin
Sweat glands
Sweat comes from the blood
The brain tells the body to sweat to cool itself down
The nervous systems signals the body to sweat
5 Characteristic of living systems
Metabolism: the sum of all chemical processes in the body
Two categories of:
Catabolism: the breakdown of larger molecules into smaller ones
Creates energy for vital processes
Anabolism: the construction of larger molecules from smaller ones
Synthesizes materials necessary for life (proteins)
Storages, example life fat or glucose for later
Responsiveness: the ability to detect and respond to changes in the internal or external environmental (Like the Sweat Scenario Example)
Movement
At any structural level (body, organ, cell, or cell component),
A change in the position of the limb , organ, cell, o
Growth and Differentiation
Growth= increase in number of size of cells or the material found between cells
Differentiation = specialization of cells for a specific function
Growth on cell size and or cell number differentiation of cells to become more specialized
Reproduction
Formation of new cells or new individuals
Levels of Biological Organization
Chemical level ( Does Not have the 5 characteristics of life, so it is not the smallest loi)
Atomic and molecular level, not alive, an oxygen cant respond or detect changes, or reproduce and grow.
Cellular level
Smallest living unit of the body
Tissue level
Group of cells and the materials surrounding them that work together on one task
Less tissue allows for more flexibility, lungs, the skin has many layers which keeps everything in and protected
Organ level
Grouping of two or more tissue types into a recognizable structure with a specific function
Organ System Level
Collection of related organs with a common function (sometimes an organ is part of more than one system)
Organisms Level
The living individual
Date: Jan. 22. 2025
Lecture 1.2
Science is not a collection of facts or concepts
Science is a way to:
Determine what is “fact”
Develop concepts
Use the Scientific method
FIve steps of the scientific method:
Observation
Ex: In the face of big changes in the environmental temperature, body temperature seems to be constant.
Can lead to a question but should be an answer to that question. Make it more specific and more testable.
Hypothesis and prediction
A question formed on the basis of observation.
The best hypotheses are specific and testable.
‘Core body temperature in an 18 year old sitting for one hour in a 200C (680F) room will remain constant at 37
Experimental testing
Gather data test your hypothesis
Analysis and Conclusion
Was body temperature truly constant with time?
It was fairly close to constant…
Development of a New Hypothesis
Rephrase and refine, then test again
Body temperature is one of many controlled conditions in our body's internal environment…
Examples of other controlled conditions in the body:
Glucose levels
Sodium levels
pH levels everywhere in the body
Homeostasis
Claude Bernard’s ‘relative constancy of the internal environment’
The physical and chemical parameters of living systems (e.g., temperature, pH, concentrations of im[portant molecules) tend to remain constant over time, and this keeps organisms alive.
The definition of homeostasis
“Homeostasis is the condition in which the body's internal environment remains relatively constant within physiological limits.”
Physiological Limits and vIability
Living systems exist within limits of heat, moisture, pressure, chemical composition, etc.
Picture drawn in notebook, an example of body temperatures max. and min. Physiological limit.
Maintenance of homeostasis
Negative feedback loop
Negative and Positive Feedback Loops
Negative feedback Loop:
Original stimulus reversed
Most feedback loops systems in the body are negative (reinforcing)
Used for conditions that need frequent adjustment
Result is the opposite of the stimulus
Body temperature, blood sugar levels, blood pressure, etc.
Positive feedback Loop
Seen during normal childbirth
Equilibrium vs. Steady-State
ISn't homeostasis just a fancy way of saying equilibrium?
“Homeostasis is the condition in which the body's internal environment remains relatively constant within physiological limits.”
Homeostasis is not equilibrium