The therapy-enhancement distinction is central in human genetics discussions.
Debate focuses on the morality of genetic interventions, with gene therapy seen as legitimate, while enhancement raises ethical concerns.
This essay examines the moral implications of this distinction, questioning if enhancement is inherently immoral.
Somatic Interventions: Modifies somatic (non-reproductive) cells.
Germline Interventions: Modifies germ (reproductive) cells, affecting future generations.
Four Types of Interventions:
Somatic Genetic Therapy (SGT)
Germline Genetic Therapy (GLGT)
Somatic Genetic Enhancement (SGE)
Germline Genetic Enhancement (GLGE)
Potential risks of SGT affecting germ cells complicate ethical considerations.
Morality of genetic interventions hinges on definitions of health and disease.
Value-Neutral Approach: Defines health and disease based on biological functions and capacities typical of the species (e.g., Boorse's statistical normality).
Value-Laden Approach: Defines health and disease based on social and cultural norms, allowing for subjectivity in interpretations of conditions like schizophrenia or homosexuality.
Implication: Neither approach alone can provide solid moral boundaries between therapy and enhancement.
Examination of what constitutes the goals of medicine:
Treatment and prevention of diseases.
Promotion of human health and well-being, and relief of suffering.
Enhancement procedures can serve medical goals similarly to therapeutic procedures, raising questions about ethical boundaries.
Arguments against enhancement: it changes human characteristics, while therapy preserves them.
Defining traits that constitute our humanity is complex; ethical concerns arise if such traits are altered.
Philosophical perspectives suggest:
Utilitarianism: Changes to humanness could be morally right or wrong based on outcomes.
Kantian Ethics: Changes may violate dignity and autonomy only under certain conditions.
Natural Law Theory: Argues that altering the human form is inherently wrong due to inherent moral worth.
Arguments against genetic enhancement often cite violation of unborn children's rights due to:
Experimental nature of interventions.
Rights to unmanipulated genomes or an open future.
Consideration of proxy consent and interests can complicate these assertions, suggesting that enhancement could benefit future choices.
Genetic interventions raise concerns of eugenics (manipulation of the gene pool).
Positive vs. Negative Eugenics:
Positive seeks favorable genes; negative aims to limit harmful genes.
State-sponsored eugenics raises significant moral concerns, while parental eugenics is often viewed as acceptable.
Rachels challenged moral distinctions within medical ethics.
The author stresses that both therapy and enhancement can be morally justified or unjustified based on circumstances and outcomes.
Implications for public policy should consider potential risks, benefits, and ethical considerations beyond mere classification.
The therapy-enhancement distinction may mostly address societal fears and hopes regarding genetic interventions rather than define strict moral boundaries.