MP

DSA Week 6: Nervous System

Topic 1: Divisions of the Nervous System

Topic 2: Central Nervous System

The Brain

  1. THE BRAIN STEM:

  • controls involuntary functions (breathing, heart rate, etc.)

  • connects cerebrum + cerebellum to the spinal chord

  • cranial nerves originate in brainstem

  1. Thalamus

    • relays info from the body to other areas of the brain

    • from sensory nerves in the skin to the cortex

    • mail room

  2. Hypothalamus

    • master cotrol of autonomic system

    • controls pituitary gland

    • hunger, thirst, sleep + sex

  3. Limbic System

    • emotional control

    • emotional behaviour from

      • amygdala (anger)

      • hippocampus (memories)

      • hypothalamus (regulates emotion)

  4. Cerebrum

    • contains the cerebrum

      • cerebral cortex: grey matter (nerve cell bodies) + white matter (nerve fibres)

    • conscious mind

      • aware of self + sensation

      • communicate

      • remember

      • understand

      • intitiate voluntary movement

  5. Cerebellum

    • coordinate muscle movement

    • coordination + balance

Cerebral Cortex + Lobes

  1. Frontal Lobe

    • movement

    • problem solving, reasoning

    • personality

    • language

  2. Parietal Lobe

    • processing somatosensory input

    • integrates visual + auditory information

  3. Temporal Lobe

    • hearing

    • language comprehension

    • memory

  4. Occipital Lobe

    • visual processing, perception, memory

Functional Areas of Cerebral Cortex

  1. Frontal Lobe

    • Primary motor cortex

      • relays motor commands to motor neurons → skeletal muscles

      • basically motor homunculus (weird looking guy diagram)

    • Premotor cortex

      • plans the movement

    • Broca’s area

      • language processing + speech

  2. Parietal Lobe

    • Primary somatosensory cortex

      • processes touch, temperature, pain, sensory info

      • sensory homunculus

    • Somatosensory association cortex

      • analyses sensory information + sends to understanding area

  3. Temporal Lobe

    • Primary auditory cortex

      • processes auditory information

    • Auditory association cortex

      • interprets auditory information

      • associates auditory input with other sensory input

    • Wernicke’s Area

      • comprehension of written + spoken language

  4. Occipital Lobe

    • Primary vision cortex

      • receives visual stimuli

    • Vision association cortex

      • interprets visual stimuli on past experiences

Spinal Chord

Train of nervous tissue + support cells that goes between brain + rest of body

Top: Medulla Oblongata

Bottom: Lumbar region of vertebral column

  • vertebrae protect the spinal chord

  • 26 vertebrae

  • vertebrae are disks made up of hyaline cartilage

Spinal Nerves:

  • pairs

  • spinal nerves come from the psinal chord

  • through spaces between vertebrae

  • named based on which section of the vertebral column

Spinal nerves are bunches of nerves (both motor + sensory)

  • ventral roots contain motor neurons

  • dorsal roots contain sensory neurons

  • dorsal rooot ganglion contain sensory neuron bodies

White matter in the spinal chord:

  • gray matter in the center is shaped like a butterfly

  • white matter made up of bundles of neuronal axons

  • white matter is where action potentials pass between different areas of grey matter

  • bundle of axons is called a column (dorsal column + ventral column)

Dorsal Column:

  • towards the back

Ventral Column:

  • towards the front

Lateral Column:

  • towards the side

Gray Matter in the spinal chord:

  • made up of cell bodies, axon terminals, dendrites

  • receives info + sorts info out

  • divided into horns (each horn is divided in 1/2)

Dorsal horn:

  • posterior

  • cell bodies of interneurons

  • sensory input

Ventral horn:

  • anterior

  • cell bodies of motor neurons

Lateral horn:

  • situated laterally

  • contain cell bodies of preganglionic neurons (contribute to autonomic system)

Neuronal pathways:

  • descending = motor

    • cerebral cortex to skeletal muscles

    • brainstem to automatic movement

  • ascending = sensory

    • from peripheral nerves to the cerebral cortex

Topic 3: Peripheral Nervous System + Reflexes

Receptors of the Sensory Nervous System

Types of Receptors:

  1. mechanoreceptor

    • touch + pressure + vibration + stretch

  2. thermoreceptor

    • temperature change

  3. chemoreceptor

    • respond to chemicals (smell, taste, changes in blood)

  4. nociceptor

    • pain receptor

  5. photoreceptor

    • light (eyes)

Mechanoreceptors:

  • embedded in the skin

  • touch changes the shape of the receptor

  • this triggers ion channels = action potentials

Tactile Sense Localisation:

  • precision of tactile stimuli is different for different parts of the body

  • assessed using the 2-point discrimination test

  • sensitivity is different based on parts of the body

Most sensitive = lips, fingers, palms, soles of feet

The greater receptor density = greater tactile precision

  • more neurons in the area

Receptive Feild:

  • area if stimulated leade to activity in the neuron

  • if receptive feild is small = high density of neurons

Autonomic Nervous System

Role of autonomic:

  • involuntary system

  • controls smooth muscles + organ funtions

Sympathetic: flight/flight responses

  • originates in lumbar + thoracic area

  • ganglia located close to spinal column

  • short preganglionic neuron

  • long postganglionic neuron

  • produce norepinephrine (neurotransmitter) for the adrenergenic receptors

Parasympathetic: rest/digest

  • originates in the brain + sacrum area

  • long preganglionic neuron

  • short postganglionic neuron

  • produce acetylcholine (ACh - neurotransmitters) for muscarinic receptors

Cranial Nerves

set of 12 paired nerves from the cerebrum

  • trigger different organs in head + neck

  • most are sensory fibres but some are motor neurons

Olafactory I:

  • receptors in nasal mucosa

  • sensory fibres synapse with olafactory bulb

  • doesnt enter brain stem

Optic II:

  • receptors in the retina form the optic nerve

  • nerves form the optic chiasma

  • synapse in the thalamus

Oculamotor III:

  • moves the eye

  • parasympathetic fibres dilate/constrict the pupil

  • focus lens

Trochlear IV:

  • pulley

  • motor fibres + sensory receptors connect to eye muscle

  • moves the eyeball up + down

Trigeminal V:

  • three branches

    • opthalmic

    • maxillary

    • mandibular

  • sensory: touch (temp + pain)

  • chewing muscles

Abducens VI:

  • moves eye from side to side

Facial VII:

  • facial muscles

  • sensory nerves for taste

  • stimulates glands: salivary, nasal, tears

Vestibulocochlear VIII:

  • sensory ibres from vibration receptors in the cochlear

  • equilibrium receptors canals and vestibule

Glossopharyngeal IX:

  • controls tongue + pharynx

  • motor fibres for swallowing

  • sensory fibres for taste + sensation

  • carotid body:

    • sensory fibres from chemoreceptors monitor oxygen + carbon dioxide levels

    • sensory fibres for baroreceptors monitor blood pressure

Vagus X:

  • wanderer - only cranial nerve beyond the head

  • contains sensory + parasympathetoc fibres

Spinal Accessory XI:

  • accessory part of the vagus nerve

  • motor + proprioreceptors signals from 2 large muscles in the neck

Hypoglossal XII:

  • below the tongue

  • controls tongue (chewing, speech, swallowing)

Reflexes

  • rapid motor response to stimulus

  • survival mechanisms

Simple Reflex Arc:

  • sensory brings info to spinal chord (interneuron in the spinal chord)

  • spinal chord sends out response to motor

Stretch reflex:

  • stimulus: tap stretches the tendons + muscles

  • spindles detect muscle length

  • effector: causes quadricep muscles to contract

Gag Reflex:

  • involuntary reaction clears up the airways

  • stimulus: oropharynx is touched (glossopharyngeal nerve)

  • effector: soft palate rises + contraction of palatal + pharyngeal muslces

Topic 4: Neural Pathways

Sensory + Neural Pathways

neural pathways are made up of chains of neurons

Sensory (ascending): from receptors in the periphery to the CNS

  • First order neurons: from receptors to CNS

    • cell body located in dorsal root ganglion/cranial nerve ganglion

  • Second order neurons: transmits signal from spinal chord to thalamus

    • many decussate

    • located in spinal chord/brainstem

  • Third order neurons: conduct impulses from thalamus to other area of the brain

Motor (descending) pathways: from the CNS to the periphery

  • Upper motor neurons

    • cell bodies + axons lie within CNS

    • controls LMN

  • Lower motor neurons (LMN)

    • cell bodies located in the ventral horn of the spinal chord

    • send axons to activate skeletal muscles

Characteristics:

  • decussation:

    • cross from one side of the CNS to the other (decussate) at some point

  • relay:

    • most consist of a chain of 2/3 neurons

  • somatopy:

    • Somatotopy is like a map in your brain that shows which parts of the brain control or feel different parts of your body

  • Symmetry:

    • all pathways are paired symmetrically