Skeletal Muscle Structure
Overview of Muscular Tissue
Three Types: skeletal, cardiac, & smooth.
Common Properties:
Excitability - ability to send electric action potentials (skeletal muscles completely rely on this, cardiac and smooth respond to hormones and local stimuli as well)
Contractility - shorten with force
Extensibility - stretch or extend
Elasticity - return to original length
Differences:
Cell structure, body location, how they are stimulated to contract.
Similarities: Skeletal & Smooth elongated and called fibers, shorten due to microfilaments, “myo”, “mys”, “sarco” reference
Skeletal Muscle
Huge, cigar-shaped, multinucleate cells (multiple nuclei per cell)
Largest of the muscle fiber cells “striated muscle” due to obvious stripes (arrangement of proteins)
Voluntary muscles - as only type subject to conscious control (in addition to reflex action)
Only respond to nervous system stimuli
“Skeletal, striated, voluntary”
Skeletal Muscle Fiber Structure:
Endomysium - connective tissue sheath around a muscle fiber (fiber = ~ cell)
Fascicle - a bundle of muscle fibers
Perimysium - coarser fibrous membrane sheath around a bundle of fibers
Epimysium - an even ‘tougher’ overcoat of connective tissue which covers the entire muscle
Tendon - strong cords that bind the muscle via fusing with periosteum
Abduction is a movement away from the midline – just as abducting someone is to take them away.
Adduction is a movement towards the midline.
Extension refers to a movement that increases the angle between two body parts.
Flexion refers to a movement that decreases the angle between two body parts.
Lateral rotation is a rotating movement away from the midline.
Medial rotation is a rotational movement towards the midline
Muscle Functions:
Producing movement is a common function of all types of muscles
Skeletal muscle provides three addition roles in addition to movement:
Maintaining posture
Stabilizing joints
Generating heat
Skeletal Muscle Structure
Multinucleate
Sarcolemma - plasma membrane that surrounds the muscle cells
Myofibrils - long ribbon-like organelles that fill the cytoplasm
Skeletal Muscle Structure
Sarcomeres - chains of tiny contractile units lined up end to end making up the myofibril (a portion of an organelle, not a cell)
Creates the banding pattern
Sarcomere
Alternating light and dark proteins/bands give a striated appearance
I Bands - “light” (no myosin)
A Bands - “dark” (both myosin/actin)
Z Disc - dark mid-line interruption of the light I Band (think end of sarcomere segment)
H Zone - lighter central area on the dark A Band (no actin)
M Line - tiny protein rods in the H zone that hold thick filaments together (middle of sarcomere)
Sarcomere Structure
Myosin Filament - “thick filament” made of myosin protein. Contain ATPase which split ATP in order to generate energy for contraction
Extend length of Dark A Band. Ends studded with projections called myosin heads heads or cross bridges which link to the thin filament during contraction. Actin Filament - “thin filament” made of actin protein. Anchored to z-disc (disc-like membrane). Light I bands made up of only the thin filaments from two adjacent sarcomeres. Overlap thick filaments but do not connect when muscle is relaxed allowing for a “bare zone”/H-zone which disappears during contraction
Sarcoplasmic Reticulum
A specialized smooth endoplasmic reticulum that surrounds each myofibril
Major role is to store and release calcium during contraction stimulation.