Skeletal Muscle Structure

Skeletal Muscle Structure

Overview of Muscular Tissue

  1. Three Types: skeletal, cardiac, & smooth.

Common Properties:

  1. Excitability - ability to send electric action potentials (skeletal muscles completely rely on this, cardiac and smooth respond to hormones and local stimuli as well)

  2. Contractility - shorten with force

  3. Extensibility - stretch or extend 

  4. Elasticity  - return to original length 

Differences: 

  1. Cell structure, body location, how they are stimulated to contract.

  2. Similarities: Skeletal & Smooth elongated and called fibers, shorten due to microfilaments, “myo”, “mys”, “sarco” reference

Skeletal Muscle

  1. Huge, cigar-shaped, multinucleate cells (multiple nuclei per cell)

  2. Largest of the muscle fiber cells “striated muscle” due to obvious stripes (arrangement of proteins)

  3. Voluntary muscles - as only type subject to conscious control (in addition to reflex action)

  4. Only respond to nervous system stimuli

  5. “Skeletal, striated, voluntary”

Skeletal Muscle Fiber Structure:

  1. Endomysium - connective tissue sheath around a muscle fiber (fiber = ~ cell)

  2. Fascicle - a bundle of muscle fibers

  3. Perimysium - coarser fibrous membrane sheath around a bundle of fibers

  4. Epimysium - an even ‘tougher’ overcoat of connective tissue which covers the entire muscle

  5. Tendon - strong cords that bind the muscle via fusing with periosteum 


Abduction is a movement away from the midline – just as abducting someone is to take them away. 


Adduction is a movement towards the midline. 


Extension refers to a movement that increases the angle between two body parts. 


Flexion refers to a movement that decreases the angle between two body parts. 


Lateral rotation is a rotating movement away from the midline. 


Medial rotation is a rotational movement towards the midline



Muscle Functions:

  1. Producing movement is a common function of all types of muscles

  2. Skeletal muscle provides three addition roles in addition to movement:

Maintaining posture 

Stabilizing joints 

Generating heat

Skeletal Muscle Structure

  1. Multinucleate

  2. Sarcolemma - plasma membrane that surrounds the muscle cells

  3. Myofibrils - long ribbon-like organelles that fill the cytoplasm

Skeletal Muscle Structure

  1. Sarcomeres - chains of tiny contractile units lined up end to end making up the myofibril (a portion of an organelle, not a cell)

  2. Creates the banding pattern

Sarcomere

  1. Alternating light and dark proteins/bands give a striated appearance

I Bands - “light” (no myosin)

A Bands - “dark” (both myosin/actin)

Z Disc - dark mid-line interruption of the light I Band (think end of sarcomere segment)

H Zone - lighter central area on the dark A Band (no actin)

M Line - tiny protein rods in the H zone that hold thick filaments together (middle of sarcomere)

Sarcomere Structure

  1. Myosin Filament - “thick filament” made of myosin protein. Contain ATPase which split ATP in order to generate energy for contraction

  2. Extend length of Dark A Band. Ends studded with projections called myosin heads heads or cross bridges which link to the thin filament during contraction. Actin Filament - “thin filament” made of actin protein. Anchored to z-disc (disc-like membrane). Light I bands made up of only the thin filaments from two adjacent sarcomeres. Overlap thick filaments but do not connect when muscle is relaxed allowing for a “bare zone”/H-zone which disappears during contraction

Sarcoplasmic Reticulum

  1. A specialized smooth endoplasmic reticulum that surrounds each myofibril

Major role is to store and release calcium during contraction stimulation.