Connective Tissues
Connective tissue is one of the four main types of tissues in the body, along with nervous, muscle, and epithelial tissue.
Types of Connective Tissues
Connective tissues include:
Functions of Connective Tissues
- Provide support and bind other tissues together.
- Provide insulation and protection for other tissues.
- Transport substances.
General Characteristics of Connective Tissues
- All connective tissues originate from mesenchyme stem cells.
- Vary in vascularity (presence of blood vessels).
- Composed mainly of extracellular matrix.
The extracellular matrix is a major component of connective tissue and consists of:
- Ground substance: Watery or gel-like substance secreted by cells.
- Fibers or Threads:
Loose Connective Tissue
Types of loose connective tissue:
Areolar Connective Tissue
- Mostly open space.
- Holds water and salts for surrounding tissues.
- Found under epithelium and around organs.
Adipose Connective Tissue
- Composed of fat cells (adipocytes).
- Adipocytes have large vacuoles that contain fat/oil.
- Insulates and warms the body.
- Provides nutrients to other cells.
Reticular Connective Tissue
- Contains reticular fibers, which create a stiff framework.
- Supports other cells.
Dense Connective Tissue
Types of dense connective tissue:
Regular Dense Connective Tissue
- Collagen fibers are arranged in one direction.
- Provides tensile strength, like a rope.
- Found in tendons and ligaments.
Irregular Dense Connective Tissue
- Collagen fibers are arranged in many directions.
- Provides strength in multiple directions.
- Found in capsules around organs.
Elastic Dense Connective Tissue
- Provides flexible cushioning.
- Found between vertebrae and in arteries.
Cartilage
- Avascular and lacks nerves
Types of cartilage:
- Hyaline
- Fibrocartilage
- Elastic
Hyaline Cartilage
- Glassy looking.
- Firm ground substance with lacunae (spaces for cells).
- Few collagen fibers.
- Found in the larynx, bridge of nose, and ribs.
Fibrocartilage
- Contains lots of collagen, mostly running parallel.
- Found in intervertebral discs.
Elastic Cartilage
- Highly flexible.
- More elastic fibers.
- Found in the outer ear and tip of nose.
Bone
- Calcified ground substance
Types of Bone:
- Osteocytes secrete ground substance, fibers, collagen, and fluids.
- The ground substance eventually becomes calcified and hard.
Blood
- Vascular tissue with a connective tissue nature.
Components of Blood
- Ground substance = plasma (fluid).
- Fibers = platelets, which clot the blood.
Cells in Connective Tissue
- Mast Cells
- Macrophages
- Blood Cells
Mast cells
- Detect foreign substances.
- Contain granules that secrete inflammatory chemicals.
Macrophages
- Blob-like cells that engulf invading substances or organisms.
Blood Cells
- Red Blood Cells (erythrocytes): carry oxygen.
- White Blood Cells (leukocytes): provide immune response.
Ground Substance Variation
- Connective tissues can have different types of ground substances in the extracellular matrix.
- Cartilage has a flexible ground substance.
- Bone has a calcified ground substance.
- Blood has a fluid ground substance.