1st year Pg

Introduction to 1st Year Subjects

• Importance of 1st Year Subjects: Anatomy, Physiology, and Biochemistry.

• Key determining factors for NEET PG and NICT examination ranks.

Biochemistry

• Considered the easiest subject to score in NEET PG.

• Recommended resources:

  • Marrow's revision video notes.

  • MCQ discussion videos.

• Focus areas:

  • Nutritional biochemistry and vitamins.

  • At least 2-3 questions from vitamins yearly.

  • Important vitamins include the B group (B1, B2, B3).

• Hot spots in Biochemistry:

  • Nutritional Aspects:

    • Macro and micronutrients, specific dynamic allowance, and thermogenic effects of macronutrients.

    • Micronutrients: zinc, copper (know diseases like Wilson's and Menkes).

  • Key Metabolism Areas:

    • Protein metabolism:

      • Classifications of amino acids (ketogenic vs glucogenic).

      • Important amino acids: phenylalanine, tyrosine, and their disorders (e.g., phenylketonuria).

      • Renowned for urine odor related to disorders.

      • Urea cycle and enzyme differentiation (CPS1 vs CPS2).

    • Carbohydrate metabolism:

      • Concentrate on glycogen storage disorders (keywords associated).

      • Main disorders: Von Gerkke's Disease, Pompe Disease, Corie's Disease, McArdle's Disease.

      • Be familiar with drug inhibitors affecting metabolic pathways.

      • Gluconeogenesis, sorbitol, fructose, and galactose pathways.

    • Lipid metabolism:

      • Understand alpha, beta, omega oxidation.

      • Diseases related to fatty acids (e.g., Refsum's disease).

      • Know glycosaminoglycans and their related diseases (Hurler's, Hunter's, Sanfilippo).

Anatomy

• Be prepared for straightforward questions and answers.

• Recommended resources:

  • Marrow's revision video notes.

  • Ashwini Kumar's live session on DBMCI YouTube.

• Study approach:

  • Start with embryology:

    • Focus on germ layers and derivatives.

    • Pharyngeal arches, their derivatives, and associated embryological conditions.

  • Understand general anatomy:

    • Types of joints, cartilage, collagen types.

  • Master neuroanatomy:

    • Cranial nerves and their pathways (GSE, SSV).

    • Important areas: Wernicke's, Broca's, various brain regions and their functions.

    • Know cranial foramina and their contents.

    • Understand brachial plexus and related clinical conditions.

  • Master gross anatomy:

    • Upper limb structures: clinical conditions associated with plexus injuries.

    • Thorax: mediastinal structures and associated diseases.

    • Abdomen/pelvis: key structures to know including blood supply and cross-sections.

Physiology

• Not a stand-alone subject; must integrate with other subjects (medicine, pharmacy, pathology).

• Start with general physiology:

  • Learn equations (Nernst, Goldman) and body fluid compartments.

  • Get familiar with receptor types and functions.

• Systemic physiology:

  • Study integrated with relevant topics in medicine. Know functions and pathways of key systems (renal, hematological, etc.).

  • Recommended resource: BTR integrated chapters.

• Important integration:

  • Learning the role of specific transporters, associated diseases, and their treatments.

Conclusion

• Mastering these first year subjects is essential for success in NEET PG and other competitive exams.

• Focus on high-yield topics, utilize proper study resources, and integrate knowledge for better understanding.