Lymph - a clear fluid containing white blood cells, which bathes the tissues and drains through the lymphatic system into the bloodstream.
Lymphatic Vessels - a network of vessels that transport lymph throughout the body.
Lymphoid Organs - include lymph nodes, spleen, thymus, and tonsils, which play a role in immune responses.
Fluid Balance - collects excess interstitial fluid and returns it to the bloodstream.
Fat Absorption - absorbs fats and fat-soluble vitamins from the digestive system via lacteals.
Immune Response - houses lymphocytes that help the body fight infections.
Waste Removal - removes cellular waste and other foreign materials from tissues.
Thoracic Duct: drains lymph from the left side of the head, neck, chest, left arm, and both legs. It is located along the spine and empties into the left subclavian vein.
Right Lymphatic Duct: drains lymph from the right side of the head, neck, right arm, and part of the chest, located near the right subclavian vein.
Lymph is returned to the cardiovascular system without a pumping organ through:
Muscle Contractions: surrounding skeletal muscles compress lymphatic vessels to push lymph upwards.
Valves: ensure one-way flow of lymph and prevent backflow.
Respiratory Movements: changes in thoracic pressure assist with lymph flow.
Mini-valves are specialized structures in lymphatic capillaries that allow larger particles (like proteins and bacteria) to enter while preventing backflow, ensuring effective drainage and immune function.
A lymph node is characterized by an outer cortex and inner medulla that contains germinal centers, which are areas of active lymphocyte production and proliferation.
Germinal centers are comprised of B cells and helper T cells, crucial for the adaptive immune response.
Organ | Main Function | General Structure | Location | Unique Quality |
---|---|---|---|---|
Spleen | Filters blood, recycles iron, and produces lymphocytes | Lymphoid tissue with red and white pulp | Left upper quadrant of the abdomen | Largest lymphoid organ with filtering capability |
Thymus | Maturation of T cells | Lymphoid tissue compacted to form lobules | Located behind the sternum | Site of T cell maturation, decreases in size with age |
Tonsils | Protect against pathogens entering via the mouth and nose | Lymphoid tissue forming a ring around the pharynx | Throat region | First line of immune defense in respiratory tract |
Peyer’s patches | Monitoring intestinal bacteria and preventing growth of pathogenic bacteria | Aggregated lymphoid nodules | Located in the wall of the ileum (small intestine) | More numerous in distal ileum, part of gut-associated lymphoid tissue (GALT). |