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Imperialism Rise in Nationalism • During the French and Industrial Revolution, nationalism continued to inspire nations to increase their political and economic power. • Nationalism became the ideal force in the political, economic, and cultural life in the world, becoming the first universal ideology-organizing all people into a nation state. Nationalism Defined • The strong belief that the interest of a particular nation-state is of primary importance. o Nation-State – a state where the vast majority shares the same culture and is conscious of it. It is an ideal in which cultural boundaries match up with political ones. • As an ideology, it is based on the idea that the individual’s loyalty and devotion to the nation-state surpass other individual/group interests. • Exalting one nation’s belief above all others and placing primary emphasis on promotion of its culture and interests, excluding the interests of others. Changing the World through a Nationalistic Vision • The French Revolution significantly changed the political world and how countries govern. • The Industrial Revolution significantly changed the economic world. • The Age of Imperialism (1870-1914) dramatically changed the political, economic, and social world. What is Imperialism? • Imperialism- The policy of extending the rule of authority of an empire or nation over foreign countries, or of acquiring and holding colonies and dependencies. Power and influence are done through diplomacy or military force. Reasons for Imperialism • There are 5 main motives for empires to seek to expand their rule over other countries or territories: 1. Exploratory • Imperial nations wanted to explore territory unknown to them. • The main purpose for this exploration of new lands was for resource acquisition, medical or scientific research. o Charles Darwin • Other reasons: o Cartography (map making) o Adventure 2. Ethnocentric • Europeans acted on the concept of ethnocentrism o Ethnocentrism- the belief that one race or nation is superior to others. • Ethnocentrism developed out of Charles Darwin’s “survival of the fittest” theory. Philosophers used the theory to explain why there were superior races and inferior races. o This became known as Social Darwinism. • Most imperial nations believed that their cultural values or beliefs were superior to other nations or groups. • Believed imperial conquest would bring successful culture to inferior people. 3. Religious • Imperial expansion promoted a religious movement of people setting out to convert new members of conquered territories. • With the belief that Christianity was superior, missionaries believed it was their duty to spread Christianity to the world. • Christian missionaries established churches, and in doing so, they spread Western culture values as well. • Typically, missionaries spread the imperial nation's language through education and religious interactions. 4. Political • Patriotism and Nationalism helped spur our imperial growth, thus creating competition against other supremacies. • It was a matter of national pride, respect, and security. • Furthermore, European rivalry spurred nations for imperial conquest. Since land equaled power, the more land a country could acquire the more prestige they could wield across the globe. • Empires wanted strategic territory to ensure access for their navies and armies around the world. • The empire believed they must expand, thus they needed to be defended. 5. Economic • With the Industrial Revolution taking place during the same time, governments and private companies contributed to find ways to maximize profits. • Imperialized countries provided European factories and markets with natural resources (old and new) to manufacture products. • Trading posts were strategically placed around imperialized countries to maximize and increase profits. o Such places as the Suez Canal in Egypt which was controlled by the British provided strategic choke hold over many European powers. o Imperial powers competed over the best potential locations for resources, markets, and trade. History of Imperialism • Ancient Imperialism 600 BCE-500 CE o Roman Empire, Ancient China, Greek Empire, Persian Empire, Babylonian Empire. • Middle Age Imperialism (Age of Colonialism-1400-1800s) o Great Britain, Spain, Portugal, France, Netherlands (Dutch), Russia. • Age of Imperialism 1870-1914 o Great Britain, Spain, Portugal, France, Germany, Belgium, Italy, Japan, United States, Ottoman Empire, Russia. • Current Imperialism...? o U.S. Military intervention (i.e. Middle East) o Russia’s Invasion of Ukraine. Imperialism Colonialism • Refers to political or economic control, either legally or illegally. • Refers to where one nation assumes control over the other. • Creating an empire, expanding into neighboring regions and expanding the dominance far outside its borders. • Where a country conquers and rules over other regions for exploiting resources from the conquered country for the conqueror's benefit. • Foreign government controls/governs a territory without significant settlement. • Foreign government controls/governs the territory from within the land being colonized. • Little to no new settlement established on fresh territory. • Movement to settle to fresh territory. Age of Colonialism WHEN? • Started around the late 1400s and ended around the late 1700s/early 1800s. WHY? • Primary Reason: European countries, wished to find a direct trade route to Asia (China & India) and the East Indies. o Quicker and relatively more effective than land routes over Asia. • Secondary Reason: Empire expansion (land power) WHO? • Countries involved: Great Britain, France, Spain, the Dutch & Portugal. • Individuals’ knowns as Mercantilists believed that maintaining imperialized territory and colonizing the region could serve as a source of wealth, while personal motives by rulers, explorers, and missionaries could therefore promote their own agenda. o This agenda being “Glory, God and Gold”. Mercantilism • Mercantilism was a popular and main economic system for many European nations during the 16th to 18th centuries. • The main goal was to increase a nation’s wealth by promoting government rule of a nation’s economy for the purpose of enhancing state power at the expense of rival national power. • It was the economic counterpart of political absolutism. Why did mercantilists want colonies? • Mercantilists believed that a country must have an excess of exports over imports. • By colonizing territory, it provided the nation with indispensable wealth of precious raw materials. • Therefore, the claimed territory served as a market and supplier of raw materials for the mother country. Which, in time, provided an excess of exports for the nation and thus created wealth. o Development of Trading Companies to support this economic system. Hudson Bay Company – (1670). Controlled primarily North America. o Dutch East Indie Trading Company (1682) o East Indian Trading Company (1600) o Royal African Trade Company (1672) WHERE? • European nations begun to colonize the America, India and the East Indies to create a direct trade route. • Great Britain was the leading power in India, Australia and North America, South Africa. • Spain colonized central and South America. • French held Louisiana, coastal land of Africa and French Guinea. • The Dutch built an empire in the East Indies. • The Portuguese was able to take control of present-day Brazil and the southern tip of South America and Japan. Age of Colonialism • As countries started to imperialize these regions, eventually the concept of colonization took hold: • This is what makes the Age of Colonialism extremely different! End of Colonialism • By 1800, colonialism became less popular • Why? o Revolutions (Spain, France & American) o The Napoleonic Wars o Struggle for nationalism and democracy. o Exhausted all money and energy to supervise their colonies. Waiting to wake again • Imperialism would stay quiet for close to 50 years before Great Britain and France’s economies revitalized. • The outbreak of the Industrial Revolution only encouraged and revitalized European nations to begin their conquest for new territory and resources. Age of Imperialism THE SCRAMBLE FOR AFRICA 1870-1914 Conditions Prior to Imperialism of Africa  European interest in exploiting Africa was minimal.  Their economic interests & profit in Africa primarily came through coastal trade that took place during the 1500-1700s.  The slave trade became the main source of European profit.  Furthermore, disease, political instability, lack of transportation and unpredictable climate all discouraged Europeans from seeking territory. Slave Trade & the Trans-Atlantic Slave Voyages  Forced labor was not uncommon during the 13-17th Centuries. Africans and Europeans had been trading goods and people across the Mediteranea for centuries.  This all changed from 1526 to 1867, as a new system of slavery was introduced that became highly “commercialized, racialized and inherited”  By 1690, the America and West Indies saw approximately 30,000 African people shipped from Africa. A century later, that number grew to 85,000 people per year.  By 1867, approximately 12.5 million people (about twice the population of Arizona) left Africa in a slave ship. What Changed? 1. End of the Slave Trade- Left a need for trade between Europe and Africa. 2. Innovation in technology- The steam engine and iron hulled boats allowed Europe 3. Discovery of new raw materials- Explorers located vast raw materials and resources and this only spurred imperialism with Europe in the wake of the Industrial Revolution. 4. Politics- Unification of Germany and Italy left little room to expand in Europe. Germany and Italy both needed raw materials to “catch up” with Britain and France so they looked to Africa. The Scramble for Africa  The scramble started in 1870.  Although some coastal land had previously been acquired before 1870, the need for territory quickly accelerated as European countries looked t get deeper into Africa.  Within 20 years, nearly all continents were placed under imperialistic rule. Who was Involved?  Great Britain  France  Germany  Italy  Portugal  Belgium  Spain (kind) Violent Affairs  Violence broke out multiple times when European nations looked to claim the same territory.  Germ Chancellor. Otto van Bismarck. Attempted to avert the possibility of violence against the European powers.  In 1884, Bismarck organized a conference in Berlin for the European nations. The Berlin Conference (1884-85)  The conference looked to set ground rules for future annexation of African territory by European Nations.  Annexation is the forcible acquisition and assertion of legal title over one state’s territory by another state, usually following military occupation of the territory.  From a distant perspective, it looked like it would reduce tensions among European nations and avert war.  At the heart of the meeting, these European countries negotiated their claims to African territory, made it official and then mapped their regions.  Furthermore, the leaders agreed to allow free trade among imperialized territory and some homework for negotiating future European claims in Africa was established. Further Path  After the conference, european powers continued to expand their claims in Africa so that by 1900. 90% of the African territory had been claimed. A Turn towards Colonization?  Upon the imperialization of African territory, European nations and little interest in African land unless it produced economic wealth.  Therefore, European governments put little effort and expertise into these imperialized regions.  In most cases, this emat a form of indirect rule. Thus, governing the natin without sufficient settlement and government from within the mother country. Some Exceptions  There were some exemptions through in Africa as colonization was a necessary for some regions i n Africa.  Some regions where diamonds and gold were present. Government looked to protectorate the regions and establish rule and settlement in the regions.  Protectorates: A state controlled and protected by another state for defense against aggression and other law violations. Would  Some examples include South Africa, Botswana, Zimbabwe and Congo. Conclusion  Although it may appear that the Berlin Conference averted war amid the African Scramble, imperialism eventually brought the world into worldwide conflict.  With the continued desire to create an empire by European nations. World War 1 would break out which can be linked to this quest at imperialism.
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Transcription, Translation, and Protein Processing

Chapter Overview

  • RNA polymerases and sigma factors.
  • Transcription: DNA is converted to RNA.
  • The genetic code, ribosomes, and tRNAs.
  • Translation: mRNA is converted to protein.
  • How proteins are modified and folded.
  • How proteins are degraded.
  • How proteins are secreted.

Key Steps

  • The cell accesses its vast store of data in its genome by:
    • Reading a DNA template to make an RNA copy (transcription).
    • Decoding the RNA to assemble protein (translation).
  • After translation, each polypeptide is properly folded and placed at the correct cellular or extracellular location.

RNA Polymerases and Sigma Factors

  • RNA polymerase is a complex enzyme that carries out transcription by making RNA copies (transcripts) of a DNA template strand.
  • In bacteria, the RNA polymerase is made up of:
    • Core polymerase: α2, β, β'.
      • Required for the elongation phase.
    • Sigma factor: σ.
      • Required for the initiation phase.
    • Together, the core polymerase and sigma factor = holoenzyme.

Sigma Factors - Details

  • The sigma factor helps the core enzyme detect the promoter, which signals the beginning of the gene.
  • Every cell has a “housekeeping” sigma factor.
    • In Escherichia coli, it is sigma-70.
      • Recognizes consensus sequences at the –10 and –35 positions, relative to the start of the RNA transcript (+1).
  • A single bacterial species can make several different sigma factors.

Transcription of DNA to RNA

  • Transcription occurs in three phases:
    1. Initiation: RNA pol holoenzyme binds to the promoter.
      • This is followed by melting of the helix and synthesis of the first nucleotide of the RNA.
    2. Elongation: The RNA chain is extended.
    3. Termination: RNA pol detaches from the DNA, after the transcript is made.

Initiation of Transcription

  • RNA polymerase holoenzyme forms a loosely bound, closed complex with DNA.
  • The closed complex must become an open complex through the unwinding of one helical turn.
  • RNA polymerase in the open complex becomes tightly bound to DNA and so begins transcription.
    • The first ribonucleoside triphosphate (rNTP) of the new RNA chain is usually a purine (A or G).

Transcription Elongation

  • Elongation is the sequential addition of ribonucleotides from nucleoside triphosphates.
  • The original RNA polymerase continues to move along the template, synthesizing RNA at ~45 bases/sec.
  • The unwinding of DNA ahead of the moving complex forms a 17-bp transcription bubble.
  • Positive supercoils ahead are removed by DNA topoisomerases.

Transcription Termination

  • All bacterial genes use one of two known transcription termination signals:
    1. Rho-dependent
      • Relies on a protein called Rho and a strong pause site at the 3′ end of the gene.
    2. Rho-independent
      • Requires a GC-rich region of RNA, as well as 4–8 consecutive U residues.

Antibiotics That Affect Transcription

  • Antibiotics must meet two fundamental criteria:
    • They must kill or retard the growth of a pathogen, and they must not harm the host.
  • Rifamycin B
    • Selectively binds to the bacterial RNA pol.
    • Inhibits transcription initiation.
  • Actinomycin D
    • Nonselectively binds to DNA.
    • Inhibits transcription elongation.

Different Classes of RNA = Different Functions

  • Messenger RNA (mRNA): encodes proteins.
  • Ribosomal RNA (rRNA): forms ribosomes.
  • Transfer RNA (tRNA): shuttles amino acids.
  • Small RNA (sRNA): regulates transcription or translation.
  • tmRNA: frees ribosomes stuck on damaged mRNA.
  • Catalytic RNA: carries out enzymatic reactions.

Transcription Comparison - Archaea and Eukarya

  • Across all three domains, transcription of DNA into RNA proceeds in a similar manner.
    • Multisubunit DNA-dependent RNA-polymerases.
  • Archaea and Eukaryotes differ significantly from Bacteria in the termination and initiation stages of transcription.
    • The TATA-binding protein (TBP) recognizes a motif in the promoter called the TATA box.
    • The initiator proteins remain at the promoter or are removed before elongation begins.
  • Archaea and Bacteria utilize operons.
  • Archaea and Eukarya RNAP exhibit homology.

Translation of RNA to Protein

  • An mRNA molecule can be thought of as a sentence in which triplets of nucleotides, called codons, represent individual words, or amino acids.
  • Ribosomes are the machines that read the language of mRNA and convert, or translate, it into protein via the genetic code.
  • The code is degenerate or redundant.
  • The code operates universally across species.
  • Can turn stop codons into sense codons.
  • Can introduce novel amino acids such as pyrrolysine and selenocysteine into proteins.

tRNA Molecules

  • tRNAs are decoder molecules that convert the language of RNA into that of proteins.
  • tRNAs are shaped like a clover leaf (in 2D) and a boomerang (in 3D).
  • A tRNA molecule has two functional regions:
    • Anticodon: hydrogen bonds with the mRNA codon specifying an amino acid.
    • 3′ (acceptor) end: binds the amino acid.
  • tRNAs contain a large number of unusual, modified bases.
  • The charging of tRNAs is carried out by a set of enzymes called aminoacyl-tRNA synthetases.

The Ribosome Translates mRNA to Amino Acid Sequences

  • Ribosomes are composed of two subunits, each of which includes rRNA and proteins.
    • In prokaryotes, the subunits are 30S and 50S and combine to form the 70S ribosome.
  • The 70S ribosome harbors three binding sites for tRNA:
    1. A (acceptor) site: binds incoming aminoacyl-tRNA.
    2. P (peptidyl-tRNA) site: harbors the tRNA with the growing polypeptide chain.
    3. E (exit) site: binds a tRNA recently stripped of its polypeptide.
  • The ribosome makes the peptide bonds that stitch amino acids together using peptidyltransferase.
    • Part of the 23S rRNA in the large subunit.
    • Functions as a ribozyme.
    • Functions as a molecular clock (Highly conserved, with differences in rRNA sequences that increase in relation to the evolutionary distance among species).

The Three Stages of Protein Synthesis – Require Protein Factors and GTP

  • Initiation: brings the two ribosomal subunits together, placing the first amino acid in position.
    • Shine-Dalgarno sequence (finding the start): upstream, untranslated leader RNA contains a purine-rich sequence with the consensus 5′-AGGAGGU-3′.
  • Elongation: sequentially adds amino acids as directed by mRNA transcript.
  • Termination: releases the completed protein and recycles ribosomal subunits.

Antibiotics That Affect Translation

  • Streptomycin: inhibits 70S ribosome formation.
  • Tetracycline: inhibits aminoacyl-tRNA binding to the A site.
  • Chloramphenicol: inhibits peptidyltransferase.
  • Puromycin: triggers peptidyltransferase prematurely.
  • Erythromycin: causes abortive translocation.
  • Fusidic acid: prevents translocation.

Bacterial Transcription and Translation Are Coupled

  • Different ribosomes can bind simultaneously to the start of each cistron within a polycistronic mRNA.
  • Before RNA polymerase has even finished making an mRNA molecule, ribosomes will bind to the 5′ end of the mRNA and begin translating protein.
    • This is called coupled transcription and translation.
  • Coupled transcription and translation occurs near the nucleoid.
  • Translation of fully transcribed mRNA occurs at the cell poles.

Polysomes – RNA Molecule with Many Ribosomes Moving Along Its Length at the Same Time

  • Ribosomes in a polysome are closely packed and arranged helically along the mRNA.
  • Polysomes help protect the message from degrading RNases and enable the speedy production of protein from just a single mRNA molecule.

Protein Modification, Folding, and Degradation

  • Protein typically must be modified after translation either to achieve an appropriate 3D structure or to regulate its activity.
  • Protein structure may be modified after translation:
    • N-formyl group may be removed by methionine deformylase.
    • The addition of phosphoryl or methyl groups can change the activity of signal transduction.
    • The attachment of acetyl groups can regulate protein activity.
    • Lipids and sugars can be attached to proteins.
  • Mass spectrometry is used to assess posttranslational modifications.
  • A healthy cell “cleans house” by degrading damaged or unneeded proteins.

Protein Folding

  • Folding of many proteins requires assistance from other proteins called chaperones.
    • GroEL and GroES chaperones
      • Form stacked ring with a hollow center.
      • The protein fits inside the open hole.
    • DnaK chaperones
      • Do not form rings.
      • Clamp down on a polypeptide to assist folding.

Protein Degradation: Cleaning House

  • Many normal proteins contain degradation signals called degrons.
    • The N-terminal rule suggests that the N-terminal amino acid of a protein directly correlates with its stability.
  • Proteasomes are protein-degrading machines found in eukaryotes and archaea.
  • Bacteria contain ATP-dependent proteases, such as Lon and ClpP.

E. coli Protein Folding Versus Degradation Triage Pathways

  • Damaged proteins randomly enter chaperone-based refolding pathways or degradation pathways until the protein is repaired or destroyed.

Secretion: Protein Traffic Control

  • Proteins destined for the bacterial cell membrane or envelope regions require special export systems.
  • Proteins meant for the cell membrane are tagged with hydrophobic N-terminal signal sequences of 15–30 amino acids and bound by the signal recognition particle (SRP) undergo cotranslational export.
  • Many periplasmic proteins, such as SOD and maltose-binding protein, are delivered to the periplasm by a common pathway called the SecA-dependent general secretion pathway.
  • Gram-positive bacteria must also export proteins across the cell membrane and then fold and process them once they are secreted.
  • Many streptococci cluster their secretion systems at the cell membrane in an anionic phospholipid microdomain called the ExPortal.
    • The ExPortal is located near the cell septum and appears linked to peptidoglycan synthesis.

Journeys to the Outer Membrane

  • Gram-negative bacteria need to export proteins completely out of the cell.
    • For example, digestive enzymes and toxins.
  • Seven elegant secretion systems have evolved.
    • Labeled Type I–VII.
  • ABC transporters are the simplest of the protein secretion systems and make up what is called the type I protein secretion.
  • Type I protein secretion moves certain proteins directly from the cytoplasm to the environment.
  • Type I systems all have three protein components:
    1. An outer membrane channel.
    2. An ABC protein at the inner membrane.
    3. A periplasmic protein lashed to the inner membrane.
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Imperialism Rise in Nationalism • During the French and Industrial Revolution, nationalism continued to inspire nations to increase their political and economic power. • Nationalism became the ideal force in the political, economic, and cultural life in the world, becoming the first universal ideology-organizing all people into a nation state. Nationalism Defined • The strong belief that the interest of a particular nation-state is of primary importance. o Nation-State – a state where the vast majority shares the same culture and is conscious of it. It is an ideal in which cultural boundaries match up with political ones. • As an ideology, it is based on the idea that the individual’s loyalty and devotion to the nation-state surpass other individual/group interests. • Exalting one nation’s belief above all others and placing primary emphasis on promotion of its culture and interests, excluding the interests of others. Changing the World through a Nationalistic Vision • The French Revolution significantly changed the political world and how countries govern. • The Industrial Revolution significantly changed the economic world. • The Age of Imperialism (1870-1914) dramatically changed the political, economic, and social world. What is Imperialism? • Imperialism- The policy of extending the rule of authority of an empire or nation over foreign countries, or of acquiring and holding colonies and dependencies. Power and influence are done through diplomacy or military force. Reasons for Imperialism • There are 5 main motives for empires to seek to expand their rule over other countries or territories: 1. Exploratory • Imperial nations wanted to explore territory unknown to them. • The main purpose for this exploration of new lands was for resource acquisition, medical or scientific research. o Charles Darwin • Other reasons: o Cartography (map making) o Adventure 2. Ethnocentric • Europeans acted on the concept of ethnocentrism o Ethnocentrism- the belief that one race or nation is superior to others. • Ethnocentrism developed out of Charles Darwin’s “survival of the fittest” theory. Philosophers used the theory to explain why there were superior races and inferior races. o This became known as Social Darwinism. • Most imperial nations believed that their cultural values or beliefs were superior to other nations or groups. • Believed imperial conquest would bring successful culture to inferior people. 3. Religious • Imperial expansion promoted a religious movement of people setting out to convert new members of conquered territories. • With the belief that Christianity was superior, missionaries believed it was their duty to spread Christianity to the world. • Christian missionaries established churches, and in doing so, they spread Western culture values as well. • Typically, missionaries spread the imperial nation's language through education and religious interactions. 4. Political • Patriotism and Nationalism helped spur our imperial growth, thus creating competition against other supremacies. • It was a matter of national pride, respect, and security. • Furthermore, European rivalry spurred nations for imperial conquest. Since land equaled power, the more land a country could acquire the more prestige they could wield across the globe. • Empires wanted strategic territory to ensure access for their navies and armies around the world. • The empire believed they must expand, thus they needed to be defended. 5. Economic • With the Industrial Revolution taking place during the same time, governments and private companies contributed to find ways to maximize profits. • Imperialized countries provided European factories and markets with natural resources (old and new) to manufacture products. • Trading posts were strategically placed around imperialized countries to maximize and increase profits. o Such places as the Suez Canal in Egypt which was controlled by the British provided strategic choke hold over many European powers. o Imperial powers competed over the best potential locations for resources, markets, and trade. History of Imperialism • Ancient Imperialism 600 BCE-500 CE o Roman Empire, Ancient China, Greek Empire, Persian Empire, Babylonian Empire. • Middle Age Imperialism (Age of Colonialism-1400-1800s) o Great Britain, Spain, Portugal, France, Netherlands (Dutch), Russia. • Age of Imperialism 1870-1914 o Great Britain, Spain, Portugal, France, Germany, Belgium, Italy, Japan, United States, Ottoman Empire, Russia. • Current Imperialism...? o U.S. Military intervention (i.e. Middle East) o Russia’s Invasion of Ukraine. Imperialism Colonialism • Refers to political or economic control, either legally or illegally. • Refers to where one nation assumes control over the other. • Creating an empire, expanding into neighboring regions and expanding the dominance far outside its borders. • Where a country conquers and rules over other regions for exploiting resources from the conquered country for the conqueror's benefit. • Foreign government controls/governs a territory without significant settlement. • Foreign government controls/governs the territory from within the land being colonized. • Little to no new settlement established on fresh territory. • Movement to settle to fresh territory. Age of Colonialism WHEN? • Started around the late 1400s and ended around the late 1700s/early 1800s. WHY? • Primary Reason: European countries, wished to find a direct trade route to Asia (China & India) and the East Indies. o Quicker and relatively more effective than land routes over Asia. • Secondary Reason: Empire expansion (land power) WHO? • Countries involved: Great Britain, France, Spain, the Dutch & Portugal. • Individuals’ knowns as Mercantilists believed that maintaining imperialized territory and colonizing the region could serve as a source of wealth, while personal motives by rulers, explorers, and missionaries could therefore promote their own agenda. o This agenda being “Glory, God and Gold”. Mercantilism • Mercantilism was a popular and main economic system for many European nations during the 16th to 18th centuries. • The main goal was to increase a nation’s wealth by promoting government rule of a nation’s economy for the purpose of enhancing state power at the expense of rival national power. • It was the economic counterpart of political absolutism. Why did mercantilists want colonies? • Mercantilists believed that a country must have an excess of exports over imports. • By colonizing territory, it provided the nation with indispensable wealth of precious raw materials. • Therefore, the claimed territory served as a market and supplier of raw materials for the mother country. Which, in time, provided an excess of exports for the nation and thus created wealth. o Development of Trading Companies to support this economic system. Hudson Bay Company – (1670). Controlled primarily North America. o Dutch East Indie Trading Company (1682) o East Indian Trading Company (1600) o Royal African Trade Company (1672) WHERE? • European nations begun to colonize the America, India and the East Indies to create a direct trade route. • Great Britain was the leading power in India, Australia and North America, South Africa. • Spain colonized central and South America. • French held Louisiana, coastal land of Africa and French Guinea. • The Dutch built an empire in the East Indies. • The Portuguese was able to take control of present-day Brazil and the southern tip of South America and Japan. Age of Colonialism • As countries started to imperialize these regions, eventually the concept of colonization took hold: • This is what makes the Age of Colonialism extremely different! End of Colonialism • By 1800, colonialism became less popular • Why? o Revolutions (Spain, France & American) o The Napoleonic Wars o Struggle for nationalism and democracy. o Exhausted all money and energy to supervise their colonies. Waiting to wake again • Imperialism would stay quiet for close to 50 years before Great Britain and France’s economies revitalized. • The outbreak of the Industrial Revolution only encouraged and revitalized European nations to begin their conquest for new territory and resources. Age of Imperialism THE SCRAMBLE FOR AFRICA 1870-1914 Conditions Prior to Imperialism of Africa  European interest in exploiting Africa was minimal.  Their economic interests & profit in Africa primarily came through coastal trade that took place during the 1500-1700s.  The slave trade became the main source of European profit.  Furthermore, disease, political instability, lack of transportation and unpredictable climate all discouraged Europeans from seeking territory. Slave Trade & the Trans-Atlantic Slave Voyages  Forced labor was not uncommon during the 13-17th Centuries. Africans and Europeans had been trading goods and people across the Mediteranea for centuries.  This all changed from 1526 to 1867, as a new system of slavery was introduced that became highly “commercialized, racialized and inherited”  By 1690, the America and West Indies saw approximately 30,000 African people shipped from Africa. A century later, that number grew to 85,000 people per year.  By 1867, approximately 12.5 million people (about twice the population of Arizona) left Africa in a slave ship. What Changed? 1. End of the Slave Trade- Left a need for trade between Europe and Africa. 2. Innovation in technology- The steam engine and iron hulled boats allowed Europe 3. Discovery of new raw materials- Explorers located vast raw materials and resources and this only spurred imperialism with Europe in the wake of the Industrial Revolution. 4. Politics- Unification of Germany and Italy left little room to expand in Europe. Germany and Italy both needed raw materials to “catch up” with Britain and France so they looked to Africa. The Scramble for Africa  The scramble started in 1870.  Although some coastal land had previously been acquired before 1870, the need for territory quickly accelerated as European countries looked t get deeper into Africa.  Within 20 years, nearly all continents were placed under imperialistic rule. Who was Involved?  Great Britain  France  Germany  Italy  Portugal  Belgium  Spain (kind) Violent Affairs  Violence broke out multiple times when European nations looked to claim the same territory.  Germ Chancellor. Otto van Bismarck. Attempted to avert the possibility of violence against the European powers.  In 1884, Bismarck organized a conference in Berlin for the European nations. The Berlin Conference (1884-85)  The conference looked to set ground rules for future annexation of African territory by European Nations.  Annexation is the forcible acquisition and assertion of legal title over one state’s territory by another state, usually following military occupation of the territory.  From a distant perspective, it looked like it would reduce tensions among European nations and avert war.  At the heart of the meeting, these European countries negotiated their claims to African territory, made it official and then mapped their regions.  Furthermore, the leaders agreed to allow free trade among imperialized territory and some homework for negotiating future European claims in Africa was established. Further Path  After the conference, european powers continued to expand their claims in Africa so that by 1900. 90% of the African territory had been claimed. A Turn towards Colonization?  Upon the imperialization of African territory, European nations and little interest in African land unless it produced economic wealth.  Therefore, European governments put little effort and expertise into these imperialized regions.  In most cases, this emat a form of indirect rule. Thus, governing the natin without sufficient settlement and government from within the mother country. Some Exceptions  There were some exemptions through in Africa as colonization was a necessary for some regions i n Africa.  Some regions where diamonds and gold were present. Government looked to protectorate the regions and establish rule and settlement in the regions.  Protectorates: A state controlled and protected by another state for defense against aggression and other law violations. Would  Some examples include South Africa, Botswana, Zimbabwe and Congo. Conclusion  Although it may appear that the Berlin Conference averted war amid the African Scramble, imperialism eventually brought the world into worldwide conflict.  With the continued desire to create an empire by European nations. World War 1 would break out which can be linked to this quest at imperialism.
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