The build up of fatty deposits in the arterial walls, forming hardened plaque. Over time this narrows the lumen and reduces the blood flow through the arteries
Increases the chance of blood clots forming as blood cannot move freely through the blood vessels
The walls become thick and hardened, which reduces their ability to vasodilate and constrict
Blood pressure increases as the walls cannot regulate appropriately and hypertension occurs
Build up of fatty plaque in the coronary arteries that supply the heart muscle with oxygenated blood
Reduced blood and oxygen flow which reduces the cardiac muscle’s ability to respire and work effectively
Often leads to a heart attack or development of angina
A piece of plaque breaks away from the artery wall and encourage a blood clot to form
Can totally or partially block a coronary artery, and will then block the floe of oxygenated blood to the cardiac muscle
Causes death of the cells and permanent damage to the heart
Ischaemic stroke - a blockage in the cerebral artery, cutting off the blood supply to the brain (85% of strokes)
Haemorrhagic stroke - a blood vessel bursts and causes a bleed on the brain (15% of strokes)
reduces blood lipids and cholesterol levels - slows the development of atherosclerosis
decrease in blood viscosity - prevents blood clots forming and reduces BP
prevents the hardening of artery walls and improves their elasticity - slows the development of atherosclerosis and hypertension
increased coronary circulation as arterioles increase in diameter and density - reduces risk of a heart attack
cardiac hypertrophy and increased stroke volume - increases efficiency of the heart, lowers resting HR, lowers BP, reduces strain on the heart
increases blood flow and O2 transport to muscle cells - easier to perform exercise, reduced onset of fatigue, reduces strain on heart, reduced BP
decreased body fat - reduces strain on the heart
reduced BP and weight maintenance - reduces chance of a stroke by 72%
Constriction of the bronchial airways and inflammation of mucus membranes which restricts and limits breathing
shortness of breath, wheezing, coughing
made worse by pollution, allergies, pollen/ dust, exercise (cold and dry air)
airways become inflamed and narrow
thickening of bronchiole walls
increased mucus production
damage to alveoli
decreased lung tissue elasticity
increased respiratory muscle strength - decreases respiratory symptoms and alleviates asthma symptoms
decreased resting breathing rate - reduces onset of fatigue
increases surface area of alveoli and pulmonary capillaries - maximises the efficiency of gaseous exchange and increases health of respiratory membranes
inspiratory muscles are more effective - increases airflow, reduces breathlessness, reduces need for medication
maintains full use of lung tissue and elasticity - decreases the risk of infection associated with COPD