Chapter 1: Introduction to Biology
1. Science: A method for understanding the natural world through observation and experiments.
Biology: The study of living things and their interactions.
2. Importance of Biology: Helps us understand life, medicine, the environment, and genetics.
3. Characteristics of Life: Growth, reproduction, response to stimuli, metabolism, homeostasis, adaptation, organization.
4. Hierarchy of Life: Atoms → Molecules → Cells → Tissues → Organs → Organ Systems → Organism → Population → Community → Ecosystem → Biosphere.
5. Scientific Discovery Process: Observations → Questions → Hypothesis → Experiment → Data Analysis → Conclusion.
6. Hypothesis vs. Theory: A hypothesis is a testable statement; a theory is a well-supported explanation backed by evidence.
7. Variable: A factor that can change in an experiment.
• Independent: What you change.
• Dependent: What you measure.
• Controlled: Kept constant.
8. 4 Unifying Themes of Biology: Evolution, Energy Flow, Information Flow (DNA), Structure & Function Relationship.
Chapter 2: Chemistry of Life
1. Atom Structure: Made of protons (+), neutrons (0), and electrons (-).
2. Subatomic Particles:
• Protons: Positive, in nucleus.
• Neutrons: Neutral, in nucleus.
• Electrons: Negative, orbit nucleus.
3. Atomic Number vs. Atomic Mass:
• Atomic number = protons.
• Atomic mass = protons + neutrons.
4. Atoms vs. Isotopes: Isotopes have the same number of protons but different numbers of neutrons.
5. Importance of Isotopes: Used in medicine (e.g., radiation therapy, medical imaging).
6. Energy Levels: Electrons exist in shells around the nucleus, moving to higher shells requires energy.
7. Octet Rule: Atoms are stable with 8 outer electrons.
8. Ions: Atoms that gain or lose electrons to become charged.
9. Chemical Identity: Determined by the number of protons.
10. Redox Reactions:
• Oxidation = losing electrons.
• Reduction = gaining electrons.
11. How Molecules Form: Chemical bonds (ionic, covalent, hydrogen).
12. Bond Types:
• Ionic: Electrons transferred.
• Covalent: Electrons shared.
• Hydrogen: Weak bond between molecules.
13. Polar vs. Nonpolar Covalent Bonds:
• Polar: Unequal sharing (water).
• Nonpolar: Equal sharing (oxygen gas).
14. Electronegativity: An atom’s ability to attract electrons.
15. Water’s Importance: Essential for life due to cohesion, adhesion, and solvent abilities.
16. Water Ionization: Breaks into H+ and OH-.
17. Acids vs. Bases:
• Acids: Donate H+ (e.g., lemon juice).
• Bases: Accept H+ (e.g., baking soda).
18. pH Scale: 0-6 acidic, 7 neutral, 8-14 basic.
19. Buffers: Help maintain a stable pH in biological systems.
Chapter 3: Biological Molecules
1. Carbon Chemistry: Carbon can form four bonds, making complex molecules.
2. 4 Biological Macromolecules: Carbohydrates, lipids, proteins, nucleic acids.
3. Chemical Composition:
• Carbs: C, H, O
• Lipids: C, H, O
• Proteins: C, H, O, N
• Nucleic Acids: C, H, O, N, P
4. Functional Groups: Groups of atoms affecting molecule behavior (e.g., hydroxyl, carboxyl).
5. Monomers & Polymers:
• Carbs: Monosaccharides → Polysaccharides.
• Proteins: Amino acids → Polypeptides.
• Nucleic Acids: Nucleotides → DNA/RNA.
6. Dehydration vs. Hydrolysis:
• Dehydration: Removes water to build molecules.
• Hydrolysis: Adds water to break molecules.
7. Monosaccharides (simple sugars): Glucose, fructose.
8. Disaccharides (two sugars): Sucrose, lactose.
9. Polysaccharides (many sugars): Starch, cellulose, glycogen.
10. Isomers: Same formula, different structure (e.g., glucose vs. fructose).
11. Cellulose vs. Chitin: Both structural carbs, but cellulose is in plants and chitin in fungi/insects.
12. DNA vs. RNA: DNA stores genetic info, RNA helps make proteins.
13. Amino Acid Structure: Contains an R group that defines its properties.
14. Protein Structure:
• Primary: Amino acid sequence.
• Secondary: Helix or sheet.
• Tertiary: 3D shape.
• Quaternary: Multiple protein units.
15. Saturated vs. Unsaturated Fats:
• Saturated: Solid, single bonds.
• Unsaturated: Liquid, double bonds.
16. Lipids: Hydrophobic molecules like fats, oils, and phospholipids.
17. Lipids vs. Starches: Lipids store more energy per gram.
Chapter 4: Cells
1. Why Cells Are Small: Large surface area helps transport materials efficiently.
2. Plasma Membrane: Controls what enters/exits.
3. Cell Theory:
• All living things are made of cells.
• Cells are the basic unit of life.
• Cells come from existing cells.
4. Prokaryotic vs. Eukaryotic:
• Prokaryotic: Simple, no nucleus (bacteria).
• Eukaryotic: Complex, has nucleus (animals, plants).
5. Eukaryotic Organelles & Functions:
• Nucleus: DNA storage.
• Ribosomes: Make proteins.
• ER: Processes molecules.
• Golgi: Packages proteins.
• Mitochondria: Energy production.
• Lysosomes: Break down waste.
6. Cytoskeleton: Provides structure.
7. Plant vs. Animal Cells: Plants have cell walls, chloroplasts, and vacuoles.
8. Endosymbiotic Theory: Mitochondria and chloroplasts originated from bacteria.
Chapter 5: Membranes & Transport
1. Phospholipids: Make up cell membranes.
2. 4 Components of Membranes: Phospholipids, proteins, carbs, cholesterol.
3. Fluid Mosaic Model: Membrane is flexible with moving proteins.
4. Membrane Proteins: Transport, enzymes, receptors.
5. Passive Transport: No energy needed (diffusion, osmosis).
6. Active Transport: Requires energy (pumps, endocytosis).
7. Osmosis: Water moves to balance solute concentration.
8. Endocytosis: Cell takes in material (e.g., phagocytosis).
9. Exocytosis: Cell releases material.
10. Selective Permeability: Only some substances pass through membranes.