Cell part 2 vocabulary

General Terms

  1. Allele: A variant form of a gene found at a specific location on a chromosome.

  2. Cancer: A group of diseases characterized by uncontrolled growth and spread of abnormal cells.

  3. Chromosome: A thread-like structure made of DNA and proteins, containing genetic information.

  4. DNA (Deoxyribonucleic Acid): The molecule that carries genetic instructions for the development, functioning, growth, and reproduction of organisms.

  5. Gene: A segment of DNA that encodes for a specific protein or function.


Cellular and Genetic Processes

  1. Cell cycle: The series of events that a cell goes through as it grows and divides.

  2. Codon: A sequence of three nucleotides in DNA or RNA that corresponds to a specific amino acid or stop signal during protein synthesis.

  3. Differentiation: The process by which cells become specialized in structure and function.

  4. Disjunction: The separation of chromosomes or chromatids during cell division.

  5. Mutation: A change in the DNA sequence that can lead to altered protein function.

  6. Proliferation: The rapid reproduction of cells or organisms.

  7. Meiosis: A type of cell division that reduces the chromosome number by half, producing gametes (sperm and egg cells).

  8. Mitosis: The process of cell division that results in two identical daughter cells.

  9. Nondisjunction: The failure of chromosomes to separate properly during cell division.

  10. Cell density-dependent inhibition/contact inhibition: The process by which normal cells stop dividing when they come into contact with other cells.


Genetic Disorders and Inheritance

  1. Autosomal dominant disorder: A genetic condition where only one copy of a mutant gene on an autosome is sufficient to cause the disorder.

  2. Autosomal recessive disorder: A genetic condition where two copies of a mutant gene on an autosome are needed to cause the disorder.

  3. Autosome: Any chromosome that is not a sex chromosome.

  4. Dominant: An allele or trait that is expressed when only one copy is present.

  5. Recessive: An allele or trait that is only expressed when two copies are present.

  6. Heterozygous: Having two different alleles for a particular gene.

  7. Homozygous: Having two identical alleles for a particular gene.

  8. Single-gene disorder: A condition caused by a mutation in a single gene.

  9. Sex-linked disorder/X-linked disorder: A genetic disorder caused by mutations in genes on the sex chromosomes.


Specific Conditions

  1. Anemia: A condition in which the blood has a reduced capacity to carry oxygen, often due to low red blood cell count or hemoglobin levels.

  2. Anorexia: A condition characterized by a lack of appetite or an aversion to food.

  3. Benign: Referring to a condition, tumor, or growth that is not cancerous and does not spread to other parts of the body.

  4. Cachexia: A syndrome involving weight loss, muscle wasting, and fatigue, often seen in patients with chronic illnesses like cancer.

  5. Down syndrome/Trisomy 21: A genetic disorder caused by the presence of an extra copy of chromosome 21, leading to developmental and physical changes.

  6. Ectopic hormone production: The production of hormones by tissues or tumors outside their usual source.

  7. Malignant: Referring to a cancerous tumor that invades surrounding tissues and can spread to other parts of the body.

  8. Metastasis: The spread of cancer cells from the original site to other parts of the body.

  9. Monosomy: A genetic condition where one chromosome is missing in a pair.

  10. Trisomy: A genetic condition where there is an extra chromosome in a pair.

  11. Trisomy 21/Down syndrome: Another term for Down syndrome, caused by an extra copy of chromosome 21.


Medical Interventions

  1. Chemotherapy: The use of drugs to kill or slow the growth of cancer cells.

  2. Radiation therapy: The use of high-energy radiation to kill or damage cancer cells.

  3. Vascular endothelial cell growth factor (VEGF)/tumor-angiogenesis factor: A protein that stimulates the growth of new blood vessels, often used by tumors to ensure a blood supply.


Specific Proteins, Tests, and Concepts

  1. Antigen: A substance that triggers an immune response, often found on the surface of pathogens or cells.

  2. CEA (Carcinoembryonic antigen): A protein often found at elevated levels in certain cancers.

  3. Cytokine: A small protein released by cells that affects the behavior of other cells, especially in immune responses.

  4. Carrier: An individual who has one copy of a recessive allele that does not affect them but can pass it on to offspring.

  5. PSA (Prostate-specific antigen): A protein produced by the prostate gland, often measured to screen for prostate cancer.


Reproductive Cells and Concepts

  1. Germ cell: A reproductive cell (sperm or egg) that carries half the genetic information of the organism.

  2. Parent/progenitor cell: A cell that divides to produce daughter cells, contributing to growth or repair.

  3. Somatic cell: Any cell in the body that is not a reproductive cell.

  4. Stem cell: An undifferentiated cell that can give rise to specialized cell types.


Genetics and Heredity Tools

  1. Mendel’s laws: Principles of heredity, including the law of segregation and independent assortment, proposed by Gregor Mendel.

  2. Punnett squares: A diagram used to predict the genotypes and phenotypes of offspring from a genetic cross.

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