Material covers urinary, digestive, reproductive systems, and embryonic development.
Male Reproductive System
Spermatic Cord
A cord containing various structures, passing through the inguinal canal.
Composed of:
Vas deferens: Tube transporting sperm from the epididymis to the ejaculatory ducts.
Cremaster muscle: Involved in thermal regulation of the testes.
Dartos muscle: Surrounds the testes, aiding thermal regulation.
Testicular arteries: Supplies blood to the testes.
Pampiniform plexus: A network of veins draining blood from the testes. Organized as a plexus to cool blood, preventing the testes from overheating.
Nerves and Lymphatic vessels: Travel through the spermatic cord and inguinal canal.
Thermal Regulation of Testes
Testes need to be at 34 degrees Celsius for sperm production.
Dartos and cremaster muscles are crucial for thermal regulation.
Undescended Testes (Cryptorchidism)
Testes do not fully descend.
If not corrected, male will be infertile due to high body temperature.
Surgery can help testes descend and attach to the scrotum.
Inguinal Hernia
Organs or membranes protrude through the inguinal canal.
Small intestine or parietal peritoneum may peek through.
Caused by increased abdominal pressure (e.g., lifting heavy objects, straining during defecation).
Can occur during embryonic development if small intestine is dragged down with the testes.
Requires surgery to fix.
Testicular Torsion
Testes rotate, causing pain and blocking blood flow and sperm.
Can happen spontaneously or due to rapid temperature changes (e.g., alternating between hot tub and swimming pool).
Rapid changes in temperature cause the cremaster and dartos muscles to contract and relax rapidly, causing the testes to rotate.
Requires immediate medical attention.
Surgeons make an incision to rotate it back.
Varicocele
Varicose veins in the pampiniform plexus.
Blood pools, raising testes temperature, leading to infertility.
Often occurs in men in their 20s-40s.
Leading cause of infertility in men.
Testicular Cancer
Common in men in their 20s.
Treatment: Gonadectomy (removal of the testis) is required until medical technology improves.
No specific testicular cancer awareness day; men are assumed to do self-exams regularly.
*Self-examination: a cancerous lump feels like a frozen pea or peanut.
Epididymis
Contains simple columnar epithelium with stereocilia.
Functions include sperm storage, maturation, and nourishment.
Vas Deferens (Ductus Deferens)
Muscular tube that transports sperm to the ejaculatory ducts via peristalsis.
Loops around the urinary bladder.
Vasectomy
Incision on the posterior scrotum, cutting and tying off the vas deferens.
Prevents sperm from entering the ejaculatory ducts.
Most common birth control method in the US.
Reversible within a week; scar tissue makes reversal more difficult over time.
Rarely, spontaneous reattachment can occur (one in a million chance).
Sperm Pathway
Male
Seminiferous tubule (sperm production) → epididymis (maturation) → vas deferens → ejaculatory ducts → male urethra (prostatic, membranous, penile/spongy).
Membranous urethra (through the external urethral sphincter).
Penile or spongy urethra (through the penis).
Accessory Glands and Organs
Seminal vesicles.
Prostate gland.
Bulbo-urethral glands. Secrete seminal fluids that mix with the sperm cells.
Seminal Fluids Functions
Provide a fluid medium for sperm to swim in.
Nourish sperm with fructose (sugar) for ATP production.
Neutralize acidity in the male urethra and female vagina.
Bulbourethral Gland Added Function
Secretes lubricating mucus for ejaculation.
Prostate Gland
Contains the ejaculatory duct and prostatic urethra.
Contracts during ejaculation to release fluids.
Grows throughout life, potentially pinching the prosthetic urethra, causing urinary incontinence.
Medications can help loosen the prostate.
Prostate cancer is common due to continuous cell growth.
Detection: rectal exam where the medical person inserts a digit to search for nodules.
Often slow-growing; may be left untreated due to the prostate's vital functions.
Penis
Capable of expanding to five to six times its original size.
Parts include:
Roots: Located in the abdominal region.
Bulb: Underneath the bulbourethral gland.
Body/Shaft: Main region.
Glans: Head of the penis, covered by prepuce (foreskin).
Glans
The male equivalent of female clitoris.
Very sensitive and associated with orgasm, it is also covered in prepuce.
Circumcision
Surgical removal of the foreskin.
Most common surgical procedure in the United States.
Reasons include cultural, religious, and perceived health benefits (no strong medical evidence).
Erectile Tissue
Corpora cavernosa: Can be fully engorged with blood.
Corpus spongiosum: Cannot fully engorge to avoid pinching the urethra.
Process:
Vasodilation of arteries allows blood to enter erectile tissue.
Fibrous connective tissues form compartments where blood accumulates.
Venules constrict to maintain erection.
Viagra
Originally a blood pressure medication that vasodilates arteries.
Prolonged erection (over six hours) can cause blood clots and tissue damage.
Broken Penis
The capsule of erectile tissue breaks.
Caused by rigorous intercourse.
Review Questions and Concepts
Cardiac Sphincter: Located between the stomach and esophagus.
Proximal Convoluted Tubule (PCT): Secretes waste products into the nephron.
Neonatal Jaundice:
Caused by the breakdown of fetal hemoglobin into bilirubin.
Newborns have a special kind of hemoglobin to have higher affinity than the mom's hemoglobin.
Excess bilirubin accumulation leads to jaundice because of liver immaturity.
Urinary System (Blood Regulation):
Regulates water amount in blood to control blood pressure.
Kidneys produce erythropoietin (EPO), stimulating red blood cell production in response to low oxygen levels.
Colorectal Cancer:
Polyps (growths inward toward the lumen) can become cancerous.
Colonoscopies detect and remove polyps.
Diverticula are pouches in the colon wall.
Diverticulitis:
Inflammation of diverticula, potentially causing abdominal soreness.
Glomerular Ultrafiltrate:
v Fluid that comes out from the glomerulus and enters inside of the nephron.
Lithotripsy:
Uses ultrasound waves to break up kidney stones for easier passage.
Gubernaculum:
Dense regular connective tissue attached to the testes; shortens during development, pulling the testes down. Is not some thing pulling at the other end, rather that the structure just gets shorter.
Pulls down part of the Parietal Peritoneum.
Important Dates:
Histology quiz/Lecture Final: Twenty First.
Moral Data: The twenty Sixth.
Lab Practical at 10:10AM: The twenty Eighth.
Office Hours:
If a student wants to talk about the grades do so a week before finals.