Cardiac problems remain the top cause of death in the US and globally.
Risk factors can include genetic predispositions, lifestyle, and underlying health conditions.
The venous system has structures (e.g., valves) that are absent in the arterial system due to its lower pressure.
Valves help maintain unidirectional blood flow back to the heart.
Proper muscle contraction during movement helps pump blood through the veins.
Extended bed rest increases the risk of venous complications such as blood clots (Deep Vein Thrombosis, DVT).
Lack of movement can lead to varicose veins, chronic swelling, and potential venous ulcers.
Primary Prevention: No existing issues but screening for potential risks.
Secondary Prevention: Early identification and intervention to prevent disease progression.
Tertiary Prevention: Management of existing complications through education, compression stockings, and physical activity to enhance venous return.
A thrombus is a stationary blood clot, while an embolus is a clot that has detached and is traveling through the blood.
Conditions contributing to thrombosis include venous stasis, endothelial damage, and hypercoagulability.
Result of a thrombus moving from the venous system to the pulmonary arteries, leading to impaired oxygenation in the lungs.
Symptoms may include shortness of breath and decreased oxygen levels.
Diagnosis involves understanding ventilation and perfusion mismatches in the lungs.
Primary hypertension is caused by intrinsic factors such as genetics, while secondary hypertension results from other conditions.
Systolic hypertension is a critical factor for target organ damage, particularly in the heart, kidneys, and brain.
Risk factors include obesity, high sodium intake, diabetes, and family history.
Activation of neurohormonal systems (renin-angiotensin-aldosterone system) leads to vasoconstriction and fluid retention, worsening hypertension.
Long-term hypertension can result in organ damage, atherosclerosis, and vascular remodeling.
Characterized by the heart's inability to pump effectively, leading to systemic issues.
Can be classified into:
Systolic Heart Failure: Poor contractility affecting ejection fraction (EF < 40%).
Diastolic Heart Failure: The heart muscles are stiff; EF may be normal.
As cardiac output decreases, compensatory mechanisms (e.g., fluid retention, vasoconstriction) are activated but often work against the patient.
Medications may include diuretics, ACE inhibitors, beta-blockers, and inotropic agents to manage heart failure.
Cardiac output (CO) is influenced by preload (volume entering the heart) and afterload (resistance against which the heart pumps).
High preload can increase blood volume and stress the heart, whereas high afterload makes it difficult for the heart to pump effectively.
Origin from disruptions in the electrical conduction system, which regulate heart rhythm and rate.
Conditions like atrial fibrillation and ventricular fibrillation significantly impact cardiac output and can lead to impaired perfusion.
Various heart defects can lead to abnormal blood flow patterns, exerting unique and potentially harmful effects on circulation.
Conditions like patent ductus arteriosus, coarctation of the aorta, and tetralogy of Fallot require careful management and may need surgical intervention.