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NUR213: Comprehensive Study Notes

Unit Objectives

  • Etiologies of Chemical Dependency

  • Dual/Co-occurring Diagnoses and Nursing Care

  • Acute Withdrawal Process

  • Cannabis Use Across the Life Span

  • Evaluate the Effects of Addiction During the Child-bearing Period

  • Impact of Addiction on the Individual, Family, and/or Significant Others

  • Ethical and Legal Responsibilities When a Colleague is Chemically Impaired

  • Examine Family Issues, Enabling Behaviors, and Family Roles

  • Clinical Judgments Related to Patients with Substance Use Disorder

  • Teaching and Learning Principles for Patients and Family

  • Medication Treatment Options and Implications

    • Benzodiazepines

    • Central Nervous System Depressants

    • Antipsychotics

    • Vitamins

    • Narcotic Agonists

    • Narcotic Antagonists

    • Anticonvulsants

  • Multidisciplinary Treatment Planning and Collaborative Caring Interventions

  • Values and Challenges that a Nurse May Face in Caring for Patients with Substance Use Disorder

Substance Use and the Brain

  • Drugs of Abuse Target the Brain's Pleasure Center

    • Brain Reward Pathways

    • Drugs of abuse increase dopamine levels.

    • Dopamine Transporters and Receptors play critical roles.

    • Cocaine specifically affects areas such as the Frontal Cortex, Ventral Tegmental Area, and Nucleus Accumbens.

    • Natural Rewards vs. Drug-Induced Rewards

    • Normal increases in dopamine occur with natural rewards (e.g., food, music, sex).

    • Cocaine results in exaggerated dopamine increases and altered communication pathways.

Central Concepts of Substance Use Disorder

  • Definition: “A pathological use of a substance that leads to a disorder of use.” (American Psychiatric Association)

  • Key Terms:

    • Intoxication

    • Tolerance

    • Withdrawal

    • Abuse

    • Dependence

  • Substance Addiction Characterization:

    • Compulsive use and impaired control of use

    • Social impairment resulting from use

    • Physical effects including risky use

    • Un-treated addiction leads to cycles of chronic disease, disability, and death.

Common Use Disorder Drug Classes

  1. Alcohol

  2. Caffeine

  3. Cannabis

  4. Hallucinogens

  5. Inhalants

  6. Opioids

  7. Sedative/Hypnotics/Antianxiety

  8. Stimulants

  9. Tobacco

  • Process Addictions:

    • Gambling, Gaming, Shopping, Sex, Exercise, etc.

Drug Scheduling

  • Schedule I:

    • Drugs with no currently accepted medical use and a high potential for use disorder (e.g., heroin, LSD, marijuana).

  • Schedule II:

    • High potential for use disorder, leading to severe psychological or physical dependence (e.g., Vicodin, cocaine, methamphetamine).

  • Schedule III:

    • Moderate to low potential for dependence (e.g., Tylenol with codeine).

  • Schedule IV:

    • Low potential for use disorder (e.g., Xanax, Ativan).

  • Schedule V:

    • Lower potential for use disorder than Schedule IV (e.g., Robitussin AC).

Health Impacts

  • Short-term Use:

    • Temporary effects on brain function.

  • Long-term Use:

    • Permanent brain damage, increased risk of withdrawal, alterations in motivation, learning, and memory networks leading to loss of control and compulsive substance seeking.

Comorbidity

  • Psychiatric Comorbidity:

    • Co-occurring substance use disorders and mental disorders (6 out of 10 patients with substance use disorder have a co-occurring mental health disorder).

    • Importance of treating both disorders simultaneously.

  • Nursing Implications:

    • Diagnostic challenges require collaboration.

    • Increased crisis situations, longer treatment durations, and more severe medical, social, and emotional problems.

    • Greater risk of relapse and worsening psychiatric disorders.

Specific Substance Use Disorders

Caffeine Use Disorder

  • Overview:

    • Most widely used psychoactive substance globally.

    • Causes intoxication, overdose, and withdrawal symptoms.

    • Associated with psychiatric disorders (bipolar disorder, sleep disorders).

  • Intoxication Symptoms:

    • Restlessness, nervousness, flushed face, gastrointestinal disturbances, tachycardia, etc.

  • High Doses:

    • Severe effects such as fever, tachycardia, hypertension, seizures.

  • Treatment:

    • Hydration, gastric lavage, and medications to decrease symptoms.

Tobacco Use Disorder

  • Prevalence:

    • 13% of adults use tobacco; most begin before age 18.

  • Dependence Timeline:

    • Develops quickly.

  • Withdrawal Symptoms:

    • Irritability, anxiety, depression, insomnia, etc.

  • Treatment:

    • Replacement therapies, Bupropion (Zyban), Varenicline (Chantix).

  • Vaping Epidemic:

    • Rapid rise in use among adolescents.

    • Contains harmful substances leading to lung diseases.

Tobacco and Health

  • Conditions resulting from tobacco use include:

    • Cancers (e.g., lung, cervix)

    • Chronic Diseases (e.g., stroke, heart disease, COPD)

    • Reproductive effects in women (reduced fertility).

Stimulant Use Disorder

  • Overview:

    • Includes amphetamines and cocaine; second most widely used illicit substances in the US.

  • Intoxication Symptoms:

    • Hypervigilance, anger, chest pain, etc.

  • Withdrawal Symptoms:

    • Nightmares, insomnia, exhaustion, and depression.

  • Nursing Interventions:

    • Monitor vital signs and provide adequate fluids.

    • Group and individual therapy.

Cannabis Use Disorder

  • Legal Status:

    • Medical use legal in 38 states, recreational use in 24 states.

  • Terms and Effects:

    • Thc (tetrahydrocannabinol) is responsible for mind-altering effects.

    • Intoxication symptoms: tachycardia, red eyes, increased appetite, cognitive effects.

  • Withdrawal Symptoms:

    • Aggression, anxiety, decreased appetite, and sleep disturbances.

  • Assessment and Treatment:

    • Patient history & lab tests; stabilize and monitor symptoms focusing on safety.

Opioid Use Disorder

  • Historical Context:

    • Opium has been used historically for medical and recreational purposes; heroin proliferation in the late 19th century led to addiction crises.

  • Prescription Opioids:

    • Common prescriptions: oxycodone (OxyContin), hydrocodone (Vicodin), methadone.

  • Fentanyl:

    • Powerful synthetic opioid, significantly intensifying the overdose epidemic.

  • Statistics on Overdose:

    • Opioid use has significantly increased overdose death rates, with a notable part being due to synthetic opioids.

Alcohol Use Disorder

  • Prevalence and Epidemiology:

    • Most prevalent substance use disorder; disproportionately affects specific demographics (American Indians/Alaska Natives).

  • Risk Factors:

    • Genetic, neurobiological, social, and cultural influences on development of alcohol use disorders.

  • Intoxication Definition and Effects:

    • Person typically intoxicated over 80 mg/dL exhibits various effects like disinhibition and slurred speech.

  • Withdrawal Symptoms:

    • Autonomic hyperactivity, tremors, nausea, hallucinations, seizures.

    • Can lead to severe withdrawal symptoms known as Delirium Tremens.

Nursing Process in Substance Use Disorders

Assessment

  • Self, patient, family consideration. Key risks:

    • Injury

    • Fluid imbalance

    • Disturbed sensory perception.

Outcomes Identification

  • Goals focused on detoxification, motivation, and individual-centered treatment planning.

Implementation

  • Safety measures, anxiety reduction, nutrition, and educational interventions.

Evaluation

  • Assess overall treatment effectiveness and physical/behavioral changes related to goals set.

Treatment Modalities

  • Psychotherapy:

    • Cognitive Behavioral Therapy

    • Motivational Interviewing

  • Continuum of Care:

    • Detoxification, residential rehabilitation, partial hospitalization, intensive outpatient programs, and recovery groups focusing on relapse prevention strategies.

Substance Use and Childbearing

  • Impact of Substance Use Disorder During Pregnancy:

    • High rates of absent prenatal care, child behavioral difficulties, fetal alcohol syndrome.

Chemically-Impaired Nurse

  • Prevalence:

    • Significant occurrence in nursing; often goes unreported due to stigma and denial.

  • Risks and Outcomes:

    • Substance use leads to unsafe judgment and practice violations.

  • Action Steps for Addressing Impairment:

    • Prioritize patient safety, document incidents, seek support from peers and supervisors, and lead interventions on institutional policies.

Summary of Nursing Interventions

  • Engage in supportive discussions, offer treatment options, and maintain a compassionate yet firm stance on patient and institutional policies.